DK1628685T3 - Antivirale phosphonatanaloge - Google Patents

Antivirale phosphonatanaloge

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Publication number
DK1628685T3
DK1628685T3 DK04750807.2T DK04750807T DK1628685T3 DK 1628685 T3 DK1628685 T3 DK 1628685T3 DK 04750807 T DK04750807 T DK 04750807T DK 1628685 T3 DK1628685 T3 DK 1628685T3
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DK
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Prior art keywords
compounds
phosphonate analogues
antiviral phosphonate
antiviral
analogues
Prior art date
Application number
DK04750807.2T
Other languages
English (en)
Inventor
Carina E Cannizzaro
James M Chen
Xiaowu Chen
Aesop Cho
Lee S Chong
Maria Fardis
Haolun Jin
Ralph F Hirschmann
Alan X Huang
Choung U Kim
William A Lee
Constantine G Boojamra
Thorsten A Kirschberg
Christopher P Lee
Richard L Mackman
David Y Markevitch
Vidya K Prasad
Hyung-Jung Pyun
Adrian S Ray
Rosemarie Sherlock
Sundaramoorthi Swaminathan
Will Watkins
Jennifer R Zhang
David Oare
Original Assignee
Gilead Sciences Inc
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Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
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Publication of DK1628685T3 publication Critical patent/DK1628685T3/da

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    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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DK04750807.2T 2003-04-25 2004-04-26 Antivirale phosphonatanaloge DK1628685T3 (da)

Applications Claiming Priority (92)

Application Number Priority Date Filing Date Title
US46554803P 2003-04-25 2003-04-25
US46553703P 2003-04-25 2003-04-25
US46568703P 2003-04-25 2003-04-25
US46575903P 2003-04-25 2003-04-25
US46555903P 2003-04-25 2003-04-25
US46540003P 2003-04-25 2003-04-25
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