ITRM20050391A1 - Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione. - Google Patents

Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione.

Info

Publication number
ITRM20050391A1
ITRM20050391A1 IT000391A ITRM20050391A ITRM20050391A1 IT RM20050391 A1 ITRM20050391 A1 IT RM20050391A1 IT 000391 A IT000391 A IT 000391A IT RM20050391 A ITRM20050391 A IT RM20050391A IT RM20050391 A1 ITRM20050391 A1 IT RM20050391A1
Authority
IT
Italy
Prior art keywords
thiophouanosine
triposphate
procedure
preparation
medical area
Prior art date
Application number
IT000391A
Other languages
English (en)
Inventor
Sergio Baroni
Giancarlo Naccari
Original Assignee
Giuliani Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani Spa filed Critical Giuliani Spa
Priority to IT000391A priority Critical patent/ITRM20050391A1/it
Priority to IE2006/0448A priority patent/IE84917B1/en
Priority to US11/989,054 priority patent/US8114986B2/en
Priority to JP2008522169A priority patent/JP5184351B2/ja
Priority to KR1020087003951A priority patent/KR20080034947A/ko
Priority to PCT/IE2006/000077 priority patent/WO2007010515A1/en
Priority to EA200800373A priority patent/EA014186B1/ru
Priority to AU2006271164A priority patent/AU2006271164A1/en
Priority to BRPI0613668A priority patent/BRPI0613668A2/pt
Priority to CA002615980A priority patent/CA2615980A1/en
Priority to EP06766084A priority patent/EP1907407A1/en
Priority to CNA2006800302293A priority patent/CN101243102A/zh
Publication of ITRM20050391A1 publication Critical patent/ITRM20050391A1/it
Priority to IL188877A priority patent/IL188877A0/en
Priority to NO20080326A priority patent/NO20080326L/no
Priority to TNP2008000019A priority patent/TNSN08019A1/en
Priority to MA30641A priority patent/MA29696B1/fr
Priority to US13/331,805 priority patent/US8440812B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT000391A 2005-07-22 2005-07-22 Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione. ITRM20050391A1 (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IT000391A ITRM20050391A1 (it) 2005-07-22 2005-07-22 Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione.
IE2006/0448A IE84917B1 (en) 2006-06-14 Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
AU2006271164A AU2006271164A1 (en) 2005-07-22 2006-07-24 Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
CA002615980A CA2615980A1 (en) 2005-07-22 2006-07-24 Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
KR1020087003951A KR20080034947A (ko) 2005-07-22 2006-07-24 개선된 6-티오구아노신 트리포스페이트의 유사 화합물,의학 분야에 있어서의 이들의 용도 및 이들의 제조 방법
PCT/IE2006/000077 WO2007010515A1 (en) 2005-07-22 2006-07-24 Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
EA200800373A EA014186B1 (ru) 2005-07-22 2006-07-24 Усовершенствования для аналоговых соединений трифосфата 6-тиогуанозина, их применение в областях медицины и способы их получения
US11/989,054 US8114986B2 (en) 2005-07-22 2006-07-24 Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
BRPI0613668A BRPI0613668A2 (pt) 2005-07-22 2006-07-24 composto, composição farmacêutica, uso de um composto ou de uma composição farmacêutica, processo para a preparação de um composto, método de terapia e/ou tratamento
JP2008522169A JP5184351B2 (ja) 2005-07-22 2006-07-24 ６−チオグアノシン三リン酸の類縁化合物、医療分野におけるその使用、及びその調製方法に対する改良
EP06766084A EP1907407A1 (en) 2005-07-22 2006-07-24 Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
CNA2006800302293A CN101243102A (zh) 2005-07-22 2006-07-24 6-硫鸟苷三磷酸的类似化合物的改进、它们在医药领域中的用途及其制备方法
IL188877A IL188877A0 (en) 2005-07-22 2008-01-17 Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
NO20080326A NO20080326L (no) 2005-07-22 2008-01-18 Forbedringer av analoge forbindelser av 6-tioguanosintrifosfat, anvendelse av dem innen medisin, samt fremstilling av dem.
TNP2008000019A TNSN08019A1 (en) 2005-07-22 2008-01-18 Improvements to analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation
MA30641A MA29696B1 (fr) 2005-07-22 2008-02-12 Ameliorations apportees a des composes analogues de 6-thioguanosine triphosphate, leur utilisation dans les champs medicaux et procedes destines a leur preparation.
US13/331,805 US8440812B2 (en) 2005-07-22 2011-12-20 Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000391A ITRM20050391A1 (it) 2005-07-22 2005-07-22 Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione.

Publications (1)

Publication Number Publication Date
ITRM20050391A1 true ITRM20050391A1 (it) 2007-01-23

Family

ID=38157753

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000391A ITRM20050391A1 (it) 2005-07-22 2005-07-22 Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione.

Country Status (10)

Country Link
US (2) US8114986B2 (it)
JP (1) JP5184351B2 (it)
CN (1) CN101243102A (it)
BR (1) BRPI0613668A2 (it)
EA (1) EA014186B1 (it)
IL (1) IL188877A0 (it)
IT (1) ITRM20050391A1 (it)
MA (1) MA29696B1 (it)
NO (1) NO20080326L (it)
TN (1) TNSN08019A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014170712A1 (en) * 2013-04-15 2014-10-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Rac-1 inhibitors or pi3k inhibitors for preventing intestinal barrier dysfunction
WO2018013606A1 (en) 2016-07-12 2018-01-18 California Institute Of Technology Substrates for high-density cell growth and metabolite exchange

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386585A (en) 1970-11-16 1975-03-12 Wellcome Found Purine sugar derivatives
DE4418690A1 (de) * 1994-05-28 1996-01-11 Boehringer Mannheim Gmbh Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
US5733915A (en) 1995-03-30 1998-03-31 Glaxo Wellcome Inc. Use of azathioprine to treat crohn's disease
US5801159A (en) 1996-02-23 1998-09-01 Galileo Laboratories, Inc. Method and composition for inhibiting cellular irreversible changes due to stress
CZ126799A3 (cs) 1996-10-16 1999-07-14 Icn Pharmaceuticals Purinové L-nukleosidy a jejich analogy a farmaceutické prostředky, které je obsahují
US6355623B2 (en) 1998-09-24 2002-03-12 Hopital-Sainte-Justine Method of treating IBD/Crohn's disease and related conditions wherein drug metabolite levels in host blood cells determine subsequent dosage
US7018985B1 (en) 2000-08-21 2006-03-28 Inspire Pharmaceuticals, Inc. Composition and method for inhibiting platelet aggregation
ATE408593T1 (de) * 2001-05-03 2008-10-15 Galileo Lab Inc Pyruvatderivate
US7109181B2 (en) 2001-06-25 2006-09-19 Inspire Pharmaceuticals, Inc. Joint lubrication with P2Y purinergic receptor agonists
AU2002335824A1 (en) 2001-10-12 2003-04-22 Case Western Reserve University Neuronal regeneration
US7037718B2 (en) * 2001-10-26 2006-05-02 Cornell Research Foundation, Inc. Mutant purine nucleoside phosphorylase proteins and cellular delivery thereof
US7084128B2 (en) 2002-01-18 2006-08-01 Inspire Pharmaceuticals, Inc. Method for reducing intraocular pressure
EP1348466A3 (en) 2002-02-01 2003-10-29 Inspire Pharmaceuticals, Inc. Method for treating pain with adenosine-tetraphosphates
US7452901B2 (en) 2003-04-25 2008-11-18 Gilead Sciences, Inc. Anti-cancer phosphonate analogs
EA014685B1 (ru) 2003-04-25 2010-12-30 Джилид Сайэнс, Инк. Фосфонатсодержащие антивирусные соединения (варианты) и фармацевтическая композиция на их основе
WO2005020885A2 (en) * 2003-05-21 2005-03-10 Isis Pharmaceuticals, Inc. Compositions and methods for the treatment of severe acute respiratory syndrome (sars)
EP1656156A2 (en) 2003-08-13 2006-05-17 Children's Hospital Medical Center Mobilization of hematopoietic cells
US7524851B2 (en) 2003-12-05 2009-04-28 Robert Bosch Gesellschaft Fur Medizinische Forschung (Rbmf) Diagnostic methods for therapeutic compounds and methods for monitoring azathioprine therapy
GB0410105D0 (en) 2004-05-06 2004-06-09 Amersham Biosciences Uk Ltd Method for characterising compounds

Also Published As

Publication number Publication date
CN101243102A (zh) 2008-08-13
US20120094948A1 (en) 2012-04-19
TNSN08019A1 (en) 2009-07-14
MA29696B1 (fr) 2008-08-01
EA200800373A1 (ru) 2008-06-30
NO20080326L (no) 2008-04-15
US20090258837A1 (en) 2009-10-15
IE20060448A1 (en) 2007-05-16
US8440812B2 (en) 2013-05-14
EA014186B1 (ru) 2010-10-29
US20100323980A9 (en) 2010-12-23
JP5184351B2 (ja) 2013-04-17
IL188877A0 (en) 2008-04-13
BRPI0613668A2 (pt) 2017-05-02
US8114986B2 (en) 2012-02-14
JP2009502776A (ja) 2009-01-29

Similar Documents

Publication Publication Date Title
BRPI0806531A2 (pt) Composto, composição farmacêutica, agente terapêutico, e, uso do composto.
BRPI0618904A2 (pt) composto, composição farmacêutica, e, uso do composto
BRPI0614205A2 (pt) composto, composição farmacêutica, e, uso de composto
CL2007002017A1 (es) Compuestos derivados de [4,5']-bipirimidinil-6,4'-diamina; composicion farmaceutica; y uso como inhibidor de la actividad de cinasa en cancer de vejiga, cancer cervical y mieloma multiple.
BRPI0818690A2 (pt) Derivados de quinazolinediona, sua preparação e seus usos terapêuticos.
BRPI0812766A2 (pt) 4-cloro-4-alcóxi-1,1,1-triflúor-2-butanonas, preparação das mesmas e uso das mesmas no preparo de 4-alcóxi-1,1,1-triflúor-3-buten-2-onas
ITMI20031570A1 (it) Composizione per uso dietetico, farmaceutico o cosmetico
NO20080412L (no) Ny fysiologisk forbindelse Nesfatin, forbindelse relevant dertil og anvendelse av forbindelsene
BRPI0720323A2 (pt) composto, método de tratamento, composição farmacêutica e uso do composto
BRPI0619911A2 (pt) composto, pró-droga, agente farmacêutico, e, uso do composto
ITRM20050393A1 (it) Sistema di rilascio controllato di sostanze farmacologicamente attive, processo di preparazione e impieghi in campo medico.
BRPI0813587A2 (pt) Composto, uso do mesmo, e, composição farmacêutica
DE502007005902D1 (de) -methyl-19-nor-20- spirox-4-en-3-one), sowie diese enthaltende pharmazeutische präparate
BRPI0911772A2 (pt) composto, composição farmacêutica, e, uso do composto.
DE602004016877D1 (de) Untersuchungsstuhl
BRPI0615630A2 (pt) composição farmacêutica, e, uso de sertindol
DK1940840T3 (da) 6-heteroarylpyridoindolon-derivater, fremstilling deraf og terapeutisk anvendelse deraf
CL2007003348A1 (es) Procedimiento de preparacion de 4,4'-(1-metil-1,2-etandiil)-bis-(2,6-piperazindiona); compuesto intermediario; procedimiento de preparacion y uso.
DE602004030564D1 (de) 2-substituierte phenyl-5,7-dialkyl-3,7-dihydropyrrolä2,3-dü pyrimidin-4-onderivate, deren herstellung und pharmazeutische verwendung
BRPI1012325A2 (pt) uso de microrna-199b-5p no campo médico e diagnóstico."
WO2007117572A3 (en) Optical coherence tomographic detection of cells and killing of the same
ITMI20051155A1 (it) Nuovi composti fluorurati, loro sintesi e uso.
ITRM20050391A1 (it) Composti analoghi della 6-tioguanosina trifosfato, loro uso in campo medico e procedimento per la loro preparazione.
ITRM20060688A1 (it) 2-6-difenil-4,8diazoadamantan-1-one e suoi derivati suo procedimento di preparazione e suo uso per la formulazione di soluzioni ad azione sterilizzante e disinfettante
ITTO20030850A1 (it) Procedimento per la preparazione di 4-ammino-3,5-dicloro-benzotrifloruro.