CN100482801C - 用于在真菌细胞中表达基因的启动子 - Google Patents

用于在真菌细胞中表达基因的启动子 Download PDF

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Publication number
CN100482801C
CN100482801C CNB008053324A CN00805332A CN100482801C CN 100482801 C CN100482801 C CN 100482801C CN B008053324 A CNB008053324 A CN B008053324A CN 00805332 A CN00805332 A CN 00805332A CN 100482801 C CN100482801 C CN 100482801C
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nucleic acid
seq
acid sequence
promoter
polypeptide
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Expired - Fee Related
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Chinese (zh)
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CN1367838A (zh
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R·M·伯卡
M·W·雷伊
K·布朗
S·H·布朗
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Novozymes AS
Novozymes Inc
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Novozymes AS
Novozymes Biotech Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
CNB008053324A 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子 Expired - Fee Related CN100482801C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27444999A 1999-03-22 1999-03-22
US09/274,449 1999-03-22

Related Child Applications (4)

Application Number Title Priority Date Filing Date
CN 200410031492 Division CN1526820B (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子
CNB2004100314931A Division CN100532561C (zh) 1999-03-22 2000-03-22 新的葡糖淀粉酶及编码它的核酸序列
CNA2006100999266A Division CN1940067A (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子
CNB2004100314912A Division CN100510096C (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子

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CN1367838A CN1367838A (zh) 2002-09-04
CN100482801C true CN100482801C (zh) 2009-04-29

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CN 200410031492 Expired - Fee Related CN1526820B (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子
CNB2004100314931A Expired - Fee Related CN100532561C (zh) 1999-03-22 2000-03-22 新的葡糖淀粉酶及编码它的核酸序列
CNA2006100999266A Pending CN1940067A (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子
CNB008053324A Expired - Fee Related CN100482801C (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子
CNB2004100314912A Expired - Fee Related CN100510096C (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子

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CN 200410031492 Expired - Fee Related CN1526820B (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子
CNB2004100314931A Expired - Fee Related CN100532561C (zh) 1999-03-22 2000-03-22 新的葡糖淀粉酶及编码它的核酸序列
CNA2006100999266A Pending CN1940067A (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子

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CNB2004100314912A Expired - Fee Related CN100510096C (zh) 1999-03-22 2000-03-22 用于在真菌细胞中表达基因的启动子

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EP (2) EP2278016B1 (enExample)
JP (4) JP4620253B2 (enExample)
CN (5) CN1526820B (enExample)
AU (1) AU4025700A (enExample)
DK (1) DK2278016T3 (enExample)
WO (1) WO2000056900A2 (enExample)

Families Citing this family (489)

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Publication number Priority date Publication date Assignee Title
US7883872B2 (en) 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
AU771539C (en) 1998-10-06 2005-01-13 Dyadic International (Usa), Inc. Transformation system in the field of filamentous fungal hosts
DE10036491A1 (de) * 2000-07-25 2002-02-07 Roche Diagnostics Gmbh Expression von Alkalischer Phosphatase in Hefe
US7063962B2 (en) 2001-07-20 2006-06-20 Novozymes A/S DNA sequences for regulating transcription
AUPR945901A0 (en) 2001-12-13 2002-01-24 Macquarie University Gene promoters
JP4490284B2 (ja) 2002-11-18 2010-06-23 ノボザイムス，インコーポレイティド 菌類細胞において遺伝子を発現するためのプロモーター変異体
EP1613761B1 (en) 2003-03-31 2009-09-02 Novozymes Inc. Methods for producing biological substances in enzyme-deficient mutants of aspergillus niger
CN1902310B (zh) 2003-10-28 2011-09-21 诺维信股份有限公司 具有β-葡糖苷酶活性的多肽和编码所述多肽的多核苷酸
CN1980953B (zh) 2004-01-30 2014-12-24 诺维信股份有限公司 具有分解纤维增强活性的多肽及其编码多核苷酸
EP2322630B1 (en) 2004-02-12 2016-11-16 Novozymes Inc. Polypeptides having xylanase activity and polynucleotides encoding same
PL3219806T3 (pl) 2004-03-25 2020-11-02 Novozymes, Inc. Sposoby rozkładania lub przekształcania polisacharydów ściany komórkowej roślin
US9045748B2 (en) 2004-05-27 2015-06-02 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a DNA library
ES2545612T3 (es) 2004-06-29 2015-09-14 Novozymes Inc. Polipéptidos que tienen actividad de alfa-glucosidasa y polinucleótidos que los codifican
CN1308452C (zh) * 2004-09-14 2007-04-04 上海永业农科生物工程有限公司 一种含有改组乙醇氧化酶启动子的毕赤酵母植酸酶表达系统
US7666630B2 (en) 2004-09-30 2010-02-23 Novozymes, Inc. Polypeptides having lipase activity and polynucleotides encoding same
EP1809747B1 (en) 2004-10-04 2016-12-14 Novozymes A/S Polypeptides having phytase activity and polynucleotides encoding same
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
EP1814996A2 (en) 2004-11-19 2007-08-08 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
DK2365068T3 (en) 2004-12-22 2017-05-15 Novozymes As ENZYMER FOR PROCESSING STARCH
CN101194015B (zh) * 2004-12-22 2013-05-08 诺维信北美公司 具有葡糖淀粉酶活性的多肽以及编码该多肽的多核苷酸
JP2008532533A (ja) 2005-03-16 2008-08-21 ノボザイムス アクティーゼルスカブ 糸状菌におけるデフェンシンの組換え発現
US20090142802A1 (en) 2005-03-22 2009-06-04 Novozymes A/S Polypeptides and nucleic acids encoding same
CN101253263B (zh) 2005-04-27 2014-07-02 诺维信股份有限公司 具有内切葡聚糖酶活性的多肽和编码该多肽的多核苷酸
SI1922333T1 (sl) 2005-08-26 2010-06-30 Novozymes Adenium Biotech As Polipeptidi z antimikrobno aktivnostjo in polinukleotidi ki kodirajo le te
EP2385110A3 (en) 2005-09-30 2011-11-16 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
EP1941025B1 (en) 2005-10-17 2011-06-29 Novozymes A/S Use of fungal mutants for expression of antibodies
US8262646B2 (en) * 2006-01-20 2012-09-11 Lensar, Inc. System and method for providing the shaped structural weakening of the human lens with a laser
US8143482B2 (en) 2006-03-20 2012-03-27 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
EP2004817A2 (en) 2006-03-30 2008-12-24 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
JP2009543560A (ja) 2006-07-14 2009-12-10 ノボザイムス，インコーポレイティド 真菌細胞中の遺伝子発現を上昇させる方法
WO2008008950A2 (en) 2006-07-14 2008-01-17 Novozymes, Inc. Methods for producing secreted polypeptides having biological activity
DK2046819T3 (da) 2006-07-21 2015-06-22 Novozymes Inc Fremgangsmåder til forøgelse af secernering af polypeptider med biologisk aktivitet
EP2431470B1 (en) 2006-11-30 2017-11-29 Novozymes A/S Dnase expression in recombinant host cells
US8680252B2 (en) 2006-12-10 2014-03-25 Dyadic International (Usa), Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
WO2008080093A2 (en) 2006-12-21 2008-07-03 Verenium Corporation Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
WO2008116878A1 (en) 2007-03-26 2008-10-02 Novozymes A/S Hafnia phytase
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
WO2009019314A1 (en) 2007-08-08 2009-02-12 Novozymes A/S Transferrin variants and conjugates
JP5769142B2 (ja) * 2007-09-04 2015-08-26 独立行政法人酒類総合研究所 ピヒア属酵母において異種タンパク質を高分泌させる方法
WO2009033071A2 (en) 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
WO2009037253A2 (en) 2007-09-18 2009-03-26 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
US7867745B2 (en) 2007-11-27 2011-01-11 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
DK2224822T3 (da) 2007-12-06 2014-08-25 Novozymes As Polypeptider med acetylxylanesterase-aktivitet og polynukleotider, der koder for disse
BRPI0821230A2 (pt) 2007-12-19 2019-09-24 Novozymes As "constructo de ácido nucleico, cédula microbiana hospedeira recombinante, métodos para priduzir um polipeptídeo tendo atividade intensificadora celulolítica, para produzir um mutante de uma cédula precursora, para inibir a expressão de um polipeptídeo com atividade de intensificação celulolítica em uma célula, para produzir uma proteína, para degradar ou converter um material celulósico, e, para fermentar um material celulósico"
CN102292444A (zh) 2008-11-20 2011-12-21 诺维信股份有限公司 具有淀粉分解增强活性的多肽和编码该多肽的多核苷酸
WO2010065830A1 (en) 2008-12-04 2010-06-10 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
US20110296557A1 (en) 2008-12-12 2011-12-01 Novozymes, Inc. Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
US20110269206A1 (en) 2008-12-15 2011-11-03 Novozymes, Inc Polypeptides Having Catalase Activity And Polynucleotides Encoding Same
US8633030B2 (en) 2008-12-16 2014-01-21 Novozymes, Inc. Polypeptides having carboxypeptidase activity and polynucleotides encoding same
US20110271407A1 (en) 2008-12-16 2011-11-03 Novozymes, Inc. Polypeptides Having Alpha-Mannosidase Activity And Polynucleotides Encoding Same
US8337663B2 (en) 2008-12-19 2012-12-25 Novozymes, Inc. Methods for increasing hydrolysis of cellulosic material
EP2379732A2 (en) 2008-12-19 2011-10-26 Novozymes Inc. Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase
BRPI0923026A2 (pt) 2008-12-19 2017-03-28 Novozymes Inc métodos para degradar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico.
WO2010080527A1 (en) 2008-12-19 2010-07-15 Novozymes, Inc. Methods for determining cellulolytic enhancing activity of a polypeptide
CN104293747A (zh) 2008-12-23 2015-01-21 杜邦营养生物科学有限公司 具有木聚糖酶活性的多肽
WO2010084086A1 (en) 2009-01-21 2010-07-29 Novozymes A/S Polypeptides having esterase activity and nucleic acids encoding the same
US8604277B2 (en) 2009-01-28 2013-12-10 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
US8629324B2 (en) 2009-01-30 2014-01-14 Novozymes, Inc. Polypeptides having expansin activity and polynucleotides encoding same
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010089385A1 (en) 2009-02-06 2010-08-12 Novozymes Biopharma Dk A/S Purification process
KR101722961B1 (ko) 2009-02-11 2017-04-04 알부메딕스 에이/에스 알부민 변이체 및 접합체
EP2408314A1 (en) 2009-03-17 2012-01-25 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
DK2411511T3 (en) 2009-03-24 2018-11-26 Novozymes As POLYPEPTIDES WITH ACETYLXYLANESTERASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
EP2248893A1 (en) 2009-05-06 2010-11-10 Novozymes A/S DFPase Enzymes from Octopus Vulgaris
WO2010138754A1 (en) 2009-05-29 2010-12-02 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
CN104480088A (zh) 2009-06-02 2015-04-01 诺维信股份有限公司 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸
EP2446029B1 (en) 2009-06-26 2016-08-10 Novozymes North America, Inc. Heat-stable carbonic anhydrases and their use
EP2451957B1 (en) 2009-07-07 2017-11-15 Novozymes Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN102625833A (zh) 2009-07-24 2012-08-01 诺维信公司 糖氧化酶
WO2011014458A1 (en) 2009-07-28 2011-02-03 Novozymes, Inc. Polypeptides having phytase activity and polynucleotides encoding same
WO2011015633A1 (en) 2009-08-07 2011-02-10 Novozymes A/S Method of producing a sweet protein
EP2467476A1 (en) 2009-08-21 2012-06-27 Novozymes A/S Polypeptides having isoamylase activity and polynucleotides encoding same
US8741611B2 (en) 2009-09-01 2014-06-03 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
BR112012006032A2 (pt) 2009-09-17 2015-09-08 Novozymes Inc polipetídeo isolado, composição, célula hospedeira recombinante, métodos para produzir o polipetídeo, um polipetídeo tendo atividade realçadora celulolítica, um mutante de uma célula precursora, uma proteína e um produto de fermentação, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo(rsrna), e, métodos para inibir a expressão de um polipetídeo tendo atividade realçadora celulolítica em uma célula, degradar ou converter um polipetídeo isolado, composição, célula hospedeira recombinante, métodos para produzir o polipetídeo, um polipetídeo tendo atividade realçadora celulolítica, um mutante de uma célula precursora, uma proteína e um produto de fermentação, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo (dsrna), e, métodos para inibir a expressão de um polipetídeo tendo atividade realçadora celulolítica em uma célula, degradar ou converter um material celulósico e fermentar um material celulósico.
EP2478095A1 (en) 2009-09-18 2012-07-25 Novozymes Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
CN104946427A (zh) 2009-09-25 2015-09-30 诺维信公司 蛋白酶变体的用途
EP2480650B1 (en) 2009-09-25 2017-03-22 Novozymes A/S Subtilase variants
WO2011041397A1 (en) 2009-09-29 2011-04-07 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US8211665B2 (en) 2009-09-29 2012-07-03 Novozymes, Inc. Polypeptides having xylanase activity and polynucleotides encoding same
EP2977382A3 (en) 2009-09-30 2016-05-11 Novozymes Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US8586829B2 (en) 2009-09-30 2013-11-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2491122A1 (en) 2009-10-23 2012-08-29 Novozymes Inc. Cellobiohydrolase variants and polynucleotides encoding same
BR112012006847A2 (pt) 2009-10-29 2015-09-08 Novozymes As polipeptídeo polinucleotídeo, célula hospedeira recombinante, métodos para produzir o polipeptídeo para produzir um mutante de uma célula parental, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação, para produzir um produto de fermentação e pra fermentar um material celulósico, planta transgênica, parte da planta ou célula da planta, molécula de rna inibitória de filamento duplo, e, composição.
ES2574054T3 (es) 2009-11-06 2016-06-14 Novozymes, Inc. Polipéptidos con actividad de xilanasa y polinucleótidos que los codifican
BR112012008260A2 (pt) 2009-11-06 2015-09-15 Novozymes Inc E Novozymes As polipeptídeo, polinucleotídeo, métodos para produzir o polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação, para fermentar um material celulósico, planta transgênica, parte da planta ou célula da planta,e, molécula de rna inibitória de filamento duplo.
WO2011057140A1 (en) 2009-11-06 2011-05-12 Novozymes, Inc. Compositions for saccharification of cellulosic material
US8916359B2 (en) * 2009-11-30 2014-12-23 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
CN102869770B (zh) 2009-11-30 2015-12-16 诺维信公司 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸
WO2011068803A1 (en) 2009-12-01 2011-06-09 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
WO2011067349A1 (en) 2009-12-03 2011-06-09 Novozymes A/S Variants of a polypeptide with lipolytic activity and improved stability
WO2011070101A1 (en) 2009-12-09 2011-06-16 Novozymes A/S Methods of producing gh8 xylanase variants
BR112012013205B1 (pt) 2009-12-18 2020-11-03 Novozymes, Inc. mutante de uma cepa parental de trichoderma reesei, e, métodos para produzir um polipeptídeo de interesse e para obter um mutante de uma cepa parental de trichoderma
US20120220513A1 (en) 2009-12-29 2012-08-30 Novozymes A/S Polypeptides Having Detergency Enhancing Effect
US9416355B2 (en) 2010-01-04 2016-08-16 Novozymes North America, Inc. Alpha-amylase variants and polynucleotides encoding same
WO2011104284A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Polypeptides having antimicrobial activity
CN102884182A (zh) 2010-03-03 2013-01-16 诺维信股份有限公司 木聚糖酶变体及编码其的多核苷酸
US8828701B2 (en) 2010-03-31 2014-09-09 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
ES2565060T3 (es) 2010-04-14 2016-03-31 Novozymes A/S Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos
CN103003298B (zh) 2010-06-04 2016-02-10 诺维信股份有限公司 在丝状真菌中产生c4二羧酸
US8835604B2 (en) 2010-06-12 2014-09-16 Adenium Biotech Aos Antimicrobial peptide variants and polynucleotides encoding same
BR112012028031A2 (pt) 2010-06-21 2019-09-24 Novozymes Inc célula hospedeira, e , métodos para produzir um ácido dicarboxílico c4 e para aumentar a produção de ácido dicarboxílico c4.
BR112012029891A2 (pt) 2010-06-21 2021-07-06 Novozymes Inc polipeptídeo isolado, uso do mesmo, composição, polinucleotídeo isolado, construção de ácido nucleico ou vetor de expressão, célula hospedeira, e, métodos para produzir e para aumentar a produção de um ácido dicarboxílico c4.
US9222095B2 (en) 2010-06-25 2015-12-29 Novozymes A/S Polynucleotides having leader sequence function
US8581042B2 (en) 2010-06-30 2013-11-12 Novozymes A/S Polypeptides having beta-glucosidase activity and polynucleotides encoding same
US8945898B2 (en) 2010-07-01 2015-02-03 Dsm Ip Assets B.V. Recombinant host cell with deficiency in non-ribosomal peptide synthase production
MX2013001540A (es) 2010-08-12 2013-04-24 Novozymes Inc Composiciones que comprende un polipeptido que tiene actividad de incremento celulolititico y un compuesto de quinona, y uso de las mismas.
CN103180438A (zh) 2010-08-24 2013-06-26 诺维信公司 热稳定性Persephonella碳酸酐酶及其用途
WO2012030858A2 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having hemicellulolytic activity and polynucleotides encoding same
WO2012030799A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US8624082B2 (en) 2010-08-30 2014-01-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
WO2012030844A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2012030845A2 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
US9187742B2 (en) 2010-08-30 2015-11-17 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
BR112013007699B1 (pt) 2010-09-30 2021-12-21 Novozymes, Inc. Variante, polinucleotídeo isolado, célula hospedeira microbiana recombinante, métodos para produzir uma variante, para degradar um material celulósico, para produzir um produto de fermentação, para fermentar um material celulósico, e, composição enzimática, formulação do caldo completo ou composição de cultura de células
ES2594528T3 (es) 2010-09-30 2016-12-20 Novozymes, Inc. Variantes de polipéptidos con actividad de mejora celulolítica y polinucleótidos que las codifican
DK2622069T3 (en) 2010-10-01 2016-02-22 Novozymes Inc Beta-glucosidasevarianter and polynucleotides encoding them
JP5944908B2 (ja) 2010-10-01 2016-07-05 ノボザイムス アクティーゼルスカブ エンドペプチダーゼ活性を有するポリペプチド及びそれをコードするポリヌクレオチド
WO2012058293A1 (en) 2010-10-26 2012-05-03 Novozymes North America, Inc. Methods of saccharifying sugarcane trash
WO2012058566A1 (en) 2010-10-29 2012-05-03 Novozymes A/S Polypeptides having succinyl-coa:aceto acetate transferase activity and polynucleotides encoding same
BR112013010353A2 (pt) 2010-10-29 2016-07-05 Novozymes As célula hospedeira recombinante de lactobacillus, e, métodos para produzir isopropanol, isopropanol e n-propanol, e propileno
EP2635689B1 (en) 2010-11-02 2015-04-15 Novozymes, Inc. Methods of pretreating cellulosic material with a gh61 polypeptide
US9212354B2 (en) 2010-11-04 2015-12-15 Novozymes Inc. Polypeptides having cellobiohydrolase activitiy and polynucleotides encoding same
CA2815804A1 (en) 2010-11-08 2012-05-18 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
CA2822856A1 (en) 2010-11-08 2012-05-18 Novozymes North America, Inc. Polypeptides having glucoamylase activity and polynucleotides encoding same
WO2012062220A1 (en) 2010-11-12 2012-05-18 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2012062817A1 (en) 2010-11-12 2012-05-18 Novozymes A/S Polypeptides having phospholipase c activity and polynucleotides encoding same
WO2012068509A1 (en) 2010-11-18 2012-05-24 Novozymes, Inc. Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US9359630B2 (en) 2010-11-30 2016-06-07 Novozymes, Inc. Promoters for expressing genes in a fungal cell
EP2649188A1 (en) 2010-12-06 2013-10-16 Novozymes North America, Inc. Methods of hydrolyzing oligomers in hemicellulosic liquor
AU2011338504B2 (en) 2010-12-07 2015-01-22 Vnomics Corp. System and method for measuring and reducing vehicle fuel waste
DK2652138T3 (en) 2010-12-16 2018-01-22 Novozymes Inc Promoters for expression of genes in a fungal cell
EP3235903B1 (en) 2011-01-26 2021-07-07 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2012103350A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
BR112013018695B1 (pt) 2011-01-26 2021-03-30 Novozymes A / S Célula hospedeira microbiana recombinante, processos para produzir um polipeptídeo, para produzir uma proteína, para degradar um material celulósico, e, construto de ácido nucleico ou vetor de expressão
DK2668266T3 (en) 2011-01-26 2018-03-26 Novozymes Inc POLYPEPTIDES WITH CELLOBIO HYDROASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
WO2012103322A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
BR112013019324B1 (pt) 2011-01-31 2021-06-08 Novozymes North America, Inc processos para refinamento enzimático de um material celulósico pré-tratado
EP2678352B1 (en) 2011-02-23 2017-12-06 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN103797114A (zh) 2011-02-23 2014-05-14 杜邦营养生物科学有限公司 生产能够水解叶绿素或叶绿素衍生物的重组酶的方法
CN103492551A (zh) 2011-02-28 2014-01-01 诺维信股份有限公司 用于生产c4-二羧酸的微生物
DK3339442T3 (da) 2011-03-09 2022-06-20 Novozymes Inc Fremgangsmåder til forøgelse af den cellulolyseforbedrende aktivitet af et polypeptid
US9409958B2 (en) 2011-03-10 2016-08-09 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2683732B1 (en) 2011-03-11 2016-08-24 DSM IP Assets B.V. Vector-host system
WO2012130120A1 (en) 2011-03-25 2012-10-04 Novozymes A/S Method for degrading or converting cellulosic material
US9410136B2 (en) 2011-03-31 2016-08-09 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
US20140080182A1 (en) 2011-03-31 2014-03-20 Novozymes, Inc. Cellulose Binding Domain Variants and Polynucleotides Encoding Same
DK2702153T3 (en) 2011-04-28 2019-03-18 Novozymes Inc Polypeptides with endoglucanase activity and polynucleotides encoding them
CN103797126A (zh) 2011-04-29 2014-05-14 诺维信股份有限公司 用于增强纤维素材料的降解或转化的方法
EP2710132A1 (en) 2011-05-19 2014-03-26 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
US8993286B2 (en) 2011-05-19 2015-03-31 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
EP2527432A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Bi-directional cytosine deaminase-encoding selection marker
CN103620029B (zh) 2011-06-24 2017-06-09 诺维信公司 具有蛋白酶活性的多肽和编码它们的多核苷酸
KR20140041801A (ko) 2011-06-30 2014-04-04 노보자임스 에이/에스 알파-아밀라제 스크리닝 방법
JP6204352B2 (ja) 2011-06-30 2017-09-27 ノボザイムス アクティーゼルスカブ α−アミラーゼ変異体
CN103781910B (zh) 2011-07-06 2019-04-23 诺维信公司 α淀粉酶变体及其编码多核苷酸
EP2732033A1 (en) 2011-07-15 2014-05-21 Novozymes A/S Lipase variants and polynucleotides encoding same
US20140147895A1 (en) 2011-07-22 2014-05-29 Novozymes A/S Processes for Pretreating Cellulosic Material and Improving Hydrolysis Thereof
WO2013019827A2 (en) 2011-08-04 2013-02-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
EP2739728B1 (en) 2011-08-04 2017-07-12 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2013021060A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021059A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9487761B2 (en) 2011-08-10 2016-11-08 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021065A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021064A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9382559B2 (en) 2011-08-10 2016-07-05 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021062A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP2744898A1 (en) 2011-08-15 2014-06-25 Novozymes A/S Polypeptides having cellulase activity and polynucleotides encoding same
DK2744904T3 (en) 2011-08-19 2016-07-25 Novozymes Inc Recombinant microorganisms for the preparation of C4 dicarboxylic acids
US20140295027A1 (en) 2011-08-19 2014-10-02 Novozymes A/S Polypeptides Having Protease Activity
IN2014CN02136A (enExample) 2011-08-24 2015-05-29 Novozymes Inc
WO2013028928A1 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Cellulolytic enzyme compositions and uses thereof
US9404101B2 (en) 2011-08-24 2016-08-02 Novozymes, Inc. Methods for obtaining positive transformants of a filamentous fungal host cell
US9663772B2 (en) 2011-08-24 2017-05-30 Novozymes, Inc. Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof
CA2846690A1 (en) 2011-08-26 2013-03-07 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
US9534239B2 (en) 2011-09-06 2017-01-03 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
US9994834B2 (en) 2011-09-09 2018-06-12 Novozymes A/S Polynucleotides encoding polypeptides having alpha-amylase activity and methods of making the same
US9670510B2 (en) 2011-09-13 2017-06-06 Novozymes A/S Methods of hydrolyzing and fermenting cellulosic material
WO2013043910A1 (en) 2011-09-20 2013-03-28 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
ES2628190T3 (es) 2011-09-22 2017-08-02 Novozymes A/S Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos
DK2760885T3 (en) 2011-09-30 2017-10-30 Novozymes Inc CHEMICAL POLYPEPTIDES WITH BETA-GLUCOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
CA2850070A1 (en) 2011-09-30 2013-04-04 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2751261B1 (en) 2011-09-30 2018-08-29 Novozymes, Inc. Dehydrogenase variants and polynucleotides encoding same
CN103946378B (zh) 2011-10-11 2018-04-24 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
WO2013057143A2 (en) 2011-10-17 2013-04-25 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
EP2768957B1 (en) 2011-10-17 2018-05-09 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
DK2773656T3 (da) 2011-10-31 2019-09-09 Novozymes Inc Polypeptider med cellulolyseforbedrende aktivitet og polynukleotider, som koder for dem
US9562222B2 (en) 2011-11-18 2017-02-07 Novozymes A/S Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
EP3219794B1 (en) 2011-11-21 2019-09-11 Novozymes A/S Gh61 polypeptide variants and polynucleotides encoding same
WO2013075644A1 (en) 2011-11-22 2013-05-30 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
WO2013076253A1 (en) 2011-11-25 2013-05-30 Novozymes A/S Polypeptides having lysozyme activity and polynucleotides encoding same
US9624481B2 (en) 2011-12-01 2017-04-18 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
WO2013079531A2 (en) 2011-12-02 2013-06-06 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9404093B2 (en) 2011-12-02 2016-08-02 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP3272862A1 (en) 2011-12-16 2018-01-24 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
EP2794870A4 (en) 2011-12-19 2015-06-17 Novozymes Inc POLYPEPTIDES WITH XYLANASE ACTIVITY AND POLYNUCLEOTIDES THAT CODE
DK2794869T3 (en) 2011-12-20 2018-01-02 Novozymes Inc CELLOBIO HYDROLASE VARIABLES AND POLYNUCLEOTIDES CODING THEM
CN104024408B (zh) 2011-12-28 2019-04-19 诺维信公司 具有蛋白酶活性的多肽
ES2644007T3 (es) 2012-01-26 2017-11-27 Novozymes A/S Uso de polipéptidos con actividad de proteasa en piensos para animales y en detergentes
WO2013113622A1 (en) 2012-02-03 2013-08-08 Novozymes A/S Lipase variants and polynucleotides encoding same
PL2623586T3 (pl) 2012-02-03 2018-01-31 Procter & Gamble Kompozycje i sposoby dla obróbki powierzchniowej za pomocą lipaz
BR112014018876A2 (pt) 2012-02-20 2017-07-04 Novozymes As polipeptídeo isolado com atividade endoglicanase, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, método de produção de um polipeptídeo
CN104204198B (zh) 2012-04-02 2018-09-25 诺维信公司 脂肪酶变体以及编码其的多核苷酸
BR112014024804A2 (pt) 2012-04-23 2017-07-11 Novozymes As polipeptídeo isolado tendo atividade de glucuronil esterase, composição, polinucleotídeo isolado, construção de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, métodos para a produção de um polipeptídeo, para a degradação ou conversão de um material celulósico e para a produção de um produto de fermentação
BR112014026268A2 (pt) 2012-04-23 2017-07-18 Novozymes As polipeptídeo isolado, composição, polinucleotídeo isolado, construção de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, métodos de produção de um polipeptídeo e de degradação ou conversão de um material celulósico
CN113234695A (zh) 2012-04-27 2021-08-10 诺维信股份有限公司 Gh61多肽变体以及编码其的多核苷酸
AR090971A1 (es) 2012-05-07 2014-12-17 Novozymes As Polipeptidos que tienen actividad de degradacion de xantano y polinucleotidos que los codifican
EP2855670A2 (en) 2012-05-31 2015-04-08 Novozymes A/S Polypeptides having organophosphorous hydrolase activity
DK3327113T3 (da) 2012-05-31 2021-09-13 Novozymes As Forbedret svampeselektion
CN104394708A (zh) 2012-06-20 2015-03-04 诺维信公司 具有蛋白酶活性的多肽在动物饲料和洗涤剂中的用途
MX2015000312A (es) 2012-07-12 2015-04-10 Novozymes As Polipeptidos que tienen actividad lipasa y polinucleotidos que los codifican.
JP6468561B2 (ja) 2012-07-19 2019-02-13 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． ＡｇｓＥ欠損株
EP2885409A1 (en) 2012-08-17 2015-06-24 Novozymes A/S Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof
BR112015003257A2 (pt) 2012-08-17 2017-11-14 Novozymes As variante de asparaginase, métodos para produção de um produto alimentar a partir de um material alimentar, para produção de uma variante de asparaginase e para obtenção de uma variante de asparaginase, polinucleotídeo isolado, constructo de ácido nucleico, vetor de expressão, e, célula hospedeira
MX357022B (es) 2012-08-22 2018-06-25 Novozymes As Metaloproteasas de alicyclobacillus sp.
US20150203793A1 (en) 2012-08-22 2015-07-23 Novozymes A/S Metalloprotease from Exiguobacterium
AU2013311668B2 (en) 2012-09-05 2019-02-28 Novozymes A/S Polypeptides having protease activity
WO2014092832A2 (en) 2012-09-19 2014-06-19 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
JP5971661B2 (ja) * 2012-09-19 2016-08-17 国立大学法人 東京大学 神経活動依存的プロモータ活性を有するｄｎａ、及びこれを含むベクター
WO2014058896A1 (en) 2012-10-08 2014-04-17 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2906685B1 (en) 2012-10-12 2018-08-15 Novozymes A/S Polypeptides having peroxygenase activity
CN104718287B (zh) 2012-10-12 2018-02-06 诺维信公司 具有过氧合酶活性的多肽
WO2014056922A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056920A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056927A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
CN104704116B (zh) 2012-10-12 2018-09-28 诺维信公司 具有过氧合酶活性的多肽
US9458435B2 (en) 2012-10-12 2016-10-04 Novozymes A/S Polypeptides having peroxygenase activity
US20150275194A1 (en) 2012-10-24 2015-10-01 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
WO2014086706A1 (en) 2012-12-07 2014-06-12 Novozymes A/S Method for generating site-specific mutations in filamentous fungi
CN104884464B (zh) 2012-12-11 2021-02-02 诺维信公司 具有磷脂酶c活性的多肽以及对其进行编码的多核苷酸
WO2014093835A1 (en) 2012-12-14 2014-06-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2014099653A1 (en) 2012-12-17 2014-06-26 Novozymes A/S Alpha-amylases and polynucleotides encoding same
US20150337280A1 (en) 2012-12-19 2015-11-26 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
EP2934177B1 (en) 2012-12-21 2017-10-25 Novozymes A/S Polypeptides having protease activiy and polynucleotides encoding same
BR112015014624A2 (pt) 2012-12-24 2017-10-10 Novozymes As polipeptídeo isolado, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, método para tratamento de têxtil
CN104903443A (zh) 2013-01-03 2015-09-09 诺维信公司 α-淀粉酶变体以及对其进行编码的多核苷酸
EP3447136B1 (en) 2013-02-04 2020-05-13 DSM IP Assets B.V. Carbohydrate degrading polypeptide and uses thereof
US9441215B2 (en) 2013-02-06 2016-09-13 Novozymes A/S Polypeptides having protease activity
CN105164254B (zh) 2013-03-08 2019-06-28 诺维信公司 纤维二糖水解酶变体和编码它们的多核苷酸
WO2014145768A2 (en) 2013-03-15 2014-09-18 Bp Corporation North America Inc. Use of non-fungal 5' utrs in filamentous fungi
EP3533866A1 (en) 2013-03-21 2019-09-04 Novozymes A/S Polypeptides having phospholipase a activity and polynucleotides encoding same
MX360759B (es) 2013-03-21 2018-11-15 Novozymes As Polipeptidos con actividades lipasa y polinucleotidos que los codifican.
DK2986701T3 (en) 2013-04-18 2019-01-14 Novozymes As Polypeptides with protease activity and polynucleotides encoding them
WO2014177541A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
WO2014177546A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
US9556465B2 (en) 2013-05-10 2017-01-31 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
MX392247B (es) 2013-05-14 2025-03-24 Novozymes As Composiciones detergentes.
WO2014183921A1 (en) 2013-05-17 2014-11-20 Novozymes A/S Polypeptides having alpha amylase activity
CN118813589A (zh) 2013-06-06 2024-10-22 诺维信公司 α-淀粉酶变体以及对其进行编码的多核苷酸
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
US20160152925A1 (en) 2013-07-04 2016-06-02 Novozymes A/S Polypeptides Having Anti-Redeposition Effect and Polynucleotides Encoding Same
US20160160196A1 (en) 2013-07-09 2016-06-09 Novozymes A/S Polypeptides with Lipase Activity And Polynucleotides Encoding Same
CA2915336C (en) 2013-07-17 2024-03-12 Novozymes A/S Pullulanase chimeras and polynucleotides encoding same
BR112016001704A2 (pt) 2013-07-26 2017-09-19 Biomethodes Variante de endoglucanase i, ácido nucleico, vetor ou cassete de expressão, célula hospedeira, método de produção de uma variante de endoglucanase i, método de conversão de biomassa celulósica a açúcares monoméricos, e, método de produção de um produto de fermentação a partir da biomassa celulósica
CN104342419B (zh) * 2013-08-06 2017-03-08 上海康地恩生物科技有限公司 一种来源于黑葡萄穗霉的葡糖淀粉酶
EP3033420B1 (en) 2013-08-15 2018-02-21 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
WO2015059133A1 (en) 2013-10-22 2015-04-30 Novozymes A/S Cellobiose dehydrogenase variants and polynucleotides encoding same
EP3060666B1 (en) 2013-10-25 2020-09-30 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
EP3074513A1 (en) 2013-11-26 2016-10-05 Novozymes A/S Enzyme compositions and uses thereof
EP2876156A1 (en) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
US10465172B2 (en) 2013-11-29 2019-11-05 Novozymes A/S Peroxygenase variants
ES2706742T3 (es) 2013-12-02 2019-04-01 Dsm Ip Assets Bv Proteína estructuradora del hielo
CN105934514A (zh) 2013-12-11 2016-09-07 诺维信公司 角质酶变体以及对其进行编码的多核苷酸
EP2886656A1 (en) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzyme and method for preparing 4-hydroxyl benzyl alcohol and derivatives thereof
EP3453757B1 (en) 2013-12-20 2020-06-17 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
US10030237B2 (en) 2014-01-22 2018-07-24 Novozymes A/S Pullulanase variants and polynucleotides encoding same
CN106062271A (zh) 2014-03-05 2016-10-26 诺维信公司 用于改进具有木葡聚糖内糖基转移酶的纤维素纺织材料的性质的组合物和方法
EP3113609B1 (en) 2014-03-05 2019-07-31 Novozymes A/S Methods for improving post-harvest properties of agricultural crops
US20160348035A1 (en) 2014-03-05 2016-12-01 Novozymes A/S Compositions and Methods for Improving Properties of Non-Cellulosic Textile Materials with Xyloglucan Endotransglycosylase
EP3113611A1 (en) 2014-03-05 2017-01-11 Novozymes A/S Formulations comprising polymeric xyloglucan as a carrier for agriculturally beneficial agents
US20170073890A1 (en) 2014-03-05 2017-03-16 Novozymes A/S Compositions and Methods for Functionalizing and Linking Materials
EP3521434A1 (en) 2014-03-12 2019-08-07 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
EP3126479A1 (en) 2014-04-01 2017-02-08 Novozymes A/S Polypeptides having alpha amylase activity
EP3550015B1 (en) 2014-04-10 2021-11-10 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
DK3129457T3 (en) 2014-04-11 2018-09-17 Novozymes As detergent
CN106715465B (zh) 2014-04-15 2021-10-08 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
WO2015177153A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
WO2015177152A1 (en) 2014-05-19 2015-11-26 Dsm Ip Assets B.V. Proline-specific endoprotease
MX375798B (es) 2014-05-19 2025-03-07 Dsm Ip Assets Bv Endoproteasa específica para prolina.
AR100606A1 (es) 2014-05-27 2016-10-19 Novozymes As Variantes de lipasas y polinucleótidos que las codifican
WO2015183710A1 (en) 2014-05-30 2015-12-03 Novozymes A/S Variants of gh family 11 xylanase and polynucleotides encoding same
DK3152315T3 (en) 2014-06-06 2018-11-26 Novozymes As ENZYME COMPOSITIONS AND APPLICATIONS THEREOF
ES2712402T3 (es) 2014-06-25 2019-05-13 Novozymes As Variantes de xilanasa y polinucleótidos que las codifican
EP3183339A1 (en) 2014-08-20 2017-06-28 Novozymes A/S Xyloglucan endotransglycosylase variants and polynucleotides encoding same
WO2016037096A1 (en) 2014-09-05 2016-03-10 Novozymes A/S Carbohydrate binding module variants and polynucleotides encoding same
CN106795505A (zh) 2014-10-23 2017-05-31 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
DK3215615T3 (da) 2014-11-04 2025-08-25 Novozymes As Polypeptider med serinproteaseaktivitet og polynukleotider, der koder for samme, og deres anvendelse i dyrefoder
US10287562B2 (en) 2014-11-20 2019-05-14 Novoszymes A/S Alicyclobacillus variants and polynucleotides encoding same
EP3227438B1 (en) 2014-12-02 2024-03-27 Novozymes A/S Laccase variants and polynucleotides encoding same
EP3227442B1 (en) 2014-12-05 2022-02-16 Novozymes A/S Lipase variants and polynucleotides encoding same
CN107002049A (zh) 2014-12-16 2017-08-01 诺维信公司 具有n‑乙酰基葡萄糖胺氧化酶活性的多肽
US20170362613A1 (en) 2014-12-19 2017-12-21 Novozymes A/S Recombinant Host Cells For The Production Of 3-Hydroxypropionic Acid
AU2015366380B2 (en) 2014-12-19 2021-07-22 Novozymes A/S Compositions comprising polypeptides having xylanase activity and polypeptides having arabinofuranosidase activity
DK3262165T3 (da) 2015-02-24 2020-08-24 Novozymes As Cellobiohydrolasevarianter og polynukleotider, som koder for dem
WO2016138303A1 (en) 2015-02-27 2016-09-01 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
US10385352B2 (en) 2015-03-09 2019-08-20 Novozymes A/S Methods of introducing multiple expression constructs into a eukaryotic cell
EP3280818A2 (en) 2015-04-07 2018-02-14 Novozymes A/S Methods for selecting enzymes having lipase activity
WO2016164583A2 (en) 2015-04-07 2016-10-13 Novozymes A/S Methods for selecting enzymes having enhanced activity
AR104205A1 (es) 2015-04-09 2017-07-05 Dsm Ip Assets Bv Fosfolipasa c
US10519520B2 (en) 2015-05-27 2019-12-31 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
AU2016273208B2 (en) 2015-06-02 2021-01-21 Dsm Ip Assets B.V. Use of ice structuring protein AFP19 expressed in filamentous fungal strains for preparing food
CN108012543B (zh) 2015-06-16 2022-01-04 诺维信公司 具有脂肪酶活性的多肽和编码它们的多核苷酸
CA2981342A1 (en) 2015-06-18 2016-12-22 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
CA2987164C (en) 2015-06-26 2023-09-19 Novozymes A/S Method for producing a coffee extract
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
US10392742B2 (en) 2015-06-26 2019-08-27 Novozymes A/S Biofinishing system
US10945449B2 (en) 2015-07-02 2021-03-16 Novozymes A/S Animal feed compositions and uses thereof
CN114292829A (zh) 2015-07-06 2022-04-08 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
BR112018001041A2 (pt) 2015-07-24 2018-09-11 Novozymes Inc polipeptídeo isolado, composição, formulação de caldo inteiro ou composição de cultura de células, célula hospedeira recombinante, métodos para produção de um polipeptídeo e para produção de uma proteína, planta, parte de planta ou célula de planta transgênica, e, processos para degradação de um material celulósico ou hemicelulósico, para produção de um produto de fermentação e para fermentação de um material celulósico ou hemicelulósico.
US20180216089A1 (en) 2015-07-24 2018-08-02 Novozymes, Inc. Polypeptides Having Beta-Xylosidase Activity And Polynucleotides Encoding Same
US20180230446A1 (en) 2015-07-29 2018-08-16 Abengoa Bioenergía Nuevas Tecnologías, S.A. Expression of recombinant beta-xylosidase enzymes
WO2017035270A1 (en) 2015-08-24 2017-03-02 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
US20180171315A1 (en) 2015-09-17 2018-06-21 Novozymes A/S Polypeptides having xanthan degrading activity and polynucleotides encoding same
EP3353195B1 (en) 2015-09-22 2021-11-10 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
EP3708660A3 (en) 2015-10-07 2020-12-30 Novozymes A/S Polypeptides
ES2891339T3 (es) 2015-10-14 2022-01-27 Novozymes As Variantes de glucoamilasa y polinucleótidos que codifican las mismas
US10479981B2 (en) 2015-10-14 2019-11-19 Novozymes A/S DNase variants
CN108291215A (zh) 2015-10-14 2018-07-17 诺维信公司 具有蛋白酶活性的多肽以及编码它们的多核苷酸
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
WO2017075426A1 (en) 2015-10-30 2017-05-04 Novozymes A/S Polynucleotide constructs for in vitro and in vivo expression
CN108473974A (zh) 2015-11-24 2018-08-31 诺维信公司 具有蛋白酶活性的多肽以及编码其的多核苷酸
WO2017093318A1 (en) 2015-12-01 2017-06-08 Novozymes A/S Methods for producing lipases
US10981957B2 (en) 2015-12-02 2021-04-20 Institut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement Peptides having antimicrobial activity and new enzyme capable of converting L-configured residue in D-configured amino acid in a peptide
CA3005953A1 (en) 2015-12-22 2017-06-29 Albumedix Ltd Improved protein expression strains
JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
CA3006607A1 (en) 2015-12-30 2017-07-06 Novozymes A/S Enzyme variants and polynucleotides encoding the same
MX2018008051A (es) 2016-01-29 2018-08-23 Novozymes As Variantes de beta-glucanasa y polinucleotidos que las codifican.
WO2017140807A1 (en) 2016-02-16 2017-08-24 Monaghan Mushrooms Group Fungal polypeptides having lysozyme activity
CN108699600A (zh) 2016-02-23 2018-10-23 诺维信公司 改进的新一代测序
US10738293B2 (en) 2016-03-02 2020-08-11 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
EP3433358B1 (en) 2016-03-24 2022-07-06 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
CN109312333A (zh) 2016-04-07 2019-02-05 诺维信公司 选择具有蛋白酶活性的酶的方法
US10550398B2 (en) 2016-04-19 2020-02-04 Novozymes A/S RlmA-inactivated filamentous fungal host cell
MX391044B (es) 2016-04-29 2025-03-21 Novozymes As Composiciones detergentes y sus usos.
US20240218340A1 (en) 2016-05-03 2024-07-04 Novozymes A/S Enzyme Variants and Polynucleotides Encoding Same
EP3455352A1 (en) 2016-05-09 2019-03-20 Novozymes A/S Variant polypeptides with improved performance and use of the same
EP3246401A1 (en) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives New fatty acid decarboxylase and its uses
WO2017202979A1 (en) 2016-05-24 2017-11-30 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
MX2018014434A (es) 2016-05-24 2019-03-28 Novozymes As Composiciones que comprenden polipeptidos que tienen actividad galactanasa y polipeptidos que tienen actividad beta-galactosidasa.
WO2017202966A1 (en) 2016-05-24 2017-11-30 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
WO2017202997A1 (en) 2016-05-24 2017-11-30 Novozymes A/S Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2017211803A1 (en) 2016-06-07 2017-12-14 Novozymes A/S Co-expression of heterologous polypeptides to increase yield
EP3469076B1 (en) 2016-06-10 2020-09-02 DSM IP Assets B.V. Mutant lipase and use thereof
EP3263699B1 (en) 2016-06-30 2020-07-01 Fornia BioSolutions, Inc. Novel phytases and uses thereof
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
CN109715794A (zh) 2016-07-05 2019-05-03 诺维信公司 果胶裂解酶变体以及编码它们的多核苷酸
CN109312353A (zh) 2016-07-06 2019-02-05 诺维信公司 通过crispr-抑制来改善微生物
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
BR112019000125A2 (pt) 2016-07-08 2019-07-09 Novozymes As grânulo, polipeptídeo isolado, composição, aditivo de ração animal, ração animal peletizada, métodos de aprimoramento de um ou mais parâmetros de desempenho de um animal, de preparação de uma ração animal, para aprimorar o valor nutricional de uma ração animal, de solubilização de xilana a partir do material à base de planta e de produção do polipeptídeo, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, uso do grânulo
CA3029113A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Xylanase variants and polynucleotides encoding same
PL3485010T3 (pl) 2016-07-13 2025-01-27 The Procter & Gamble Company Warianty dnazy bacillus cibi i ich zastosowania
WO2018015295A1 (en) 2016-07-18 2018-01-25 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
CN109477083B (zh) 2016-07-20 2023-06-06 诺维信公司 热稳定性宏基因组碳酸酐酶及其用途
MX2019000743A (es) 2016-07-21 2019-05-20 Novozymes As Variantes de serinproteasa y polinucleotidos que las codifican.
CN109642225A (zh) 2016-07-21 2019-04-16 诺维信公司 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸
WO2018015444A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi
US11046736B2 (en) 2016-07-22 2021-06-29 Novozymes A/S Filamentous fungal host
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
EP3504313A1 (en) 2016-08-24 2019-07-03 Henkel AG & Co. KGaA Detergent composition comprising gh9 endoglucanase variants i
CN109563498A (zh) 2016-08-24 2019-04-02 汉高股份有限及两合公司 包含黄原胶裂解酶变体i的洗涤剂组合物
CN109844110B (zh) 2016-08-24 2023-06-06 诺维信公司 黄原胶裂解酶变体以及编码它们的多核苷酸
EP3504330A1 (en) 2016-08-24 2019-07-03 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
US20190225988A1 (en) 2016-09-15 2019-07-25 Novozymes A/S Genomic integration of DNA fragments in fungal host cells
US20210284933A1 (en) 2016-10-25 2021-09-16 Novozymes A/S Detergent compositions
CN110100011A (zh) 2016-11-21 2019-08-06 诺维信公司 Dna分子的酵母细胞提取物辅助构建
JP6899912B2 (ja) 2017-02-01 2021-07-07 ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ アミラーゼ変異体を含む洗浄組成物
BR112019015943A2 (pt) 2017-02-01 2020-04-07 Novozymes A/S variantes de alfa-amilase
EP3596199A1 (en) 2017-03-13 2020-01-22 DSM IP Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
WO2018167153A1 (en) 2017-03-17 2018-09-20 Novozymes A/S Improved filamentous fungal host cell
WO2018172155A1 (en) 2017-03-23 2018-09-27 Novozymes A/S Improved filamentous fungal host cells
WO2018177203A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
WO2018177938A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
CN110651039A (zh) 2017-03-31 2020-01-03 诺维信公司 具有rna酶活性的多肽
WO2018177936A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
US11339355B2 (en) 2017-04-04 2022-05-24 Novozymes A/S Glycosyl hydrolases
WO2018185150A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Polypeptides
WO2018185152A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Polypeptide compositions and uses thereof
CN110651048A (zh) 2017-04-11 2020-01-03 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
US11078445B2 (en) 2017-05-05 2021-08-03 Novozymes A/S Compositions comprising lipase and sulfite
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
EP3401385A1 (en) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Detergent composition comprising polypeptide comprising carbohydrate-binding domain
US11130979B2 (en) 2017-06-20 2021-09-28 Albumedix Ltd Protein expression strains
EP4650452A2 (en) 2017-06-22 2025-11-19 Novozymes A/S Xylanase variants and polynucleotides encoding same
MX2019014889A (es) 2017-06-28 2020-02-13 Novozymes As Polipeptidos que tienen actividad trehalasa y polinucleotidos que los codifican.
ES2971299T3 (es) 2017-07-24 2024-06-04 Novozymes As GH5 y GH30 en la molienda húmeda
US10081800B1 (en) 2017-08-03 2018-09-25 Fornia Biosolutions, Inc. Lactonase enzymes and methods of using same
CN111094562A (zh) 2017-08-08 2020-05-01 诺维信公司 具有海藻糖酶活性的多肽及其在产生发酵产物的方法中的用途
EP3673058A1 (en) 2017-08-24 2020-07-01 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
US20210130744A1 (en) 2017-08-24 2021-05-06 Henkel Ag & Co. Kgaa Detergent composition comprising xanthan lyase variants ii
EP3673057A1 (en) 2017-08-24 2020-07-01 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
WO2019038059A1 (en) 2017-08-24 2019-02-28 Henkel Ag & Co. Kgaa DETERGENT COMPOSITIONS COMPRISING GH9 ENDOGLUCANASE VARIANTS II
WO2019046703A1 (en) 2017-09-01 2019-03-07 Novozymes A/S METHODS OF ENHANCING GENOME EDITION IN FUNGI
WO2019043189A1 (en) 2017-09-01 2019-03-07 Novozymes A/S ANIMAL FOOD ADDITIVES COMPRISING A POLYPEPTIDE HAVING PROTEASE ACTIVITY AND USES THEREOF
PL3675647T3 (pl) 2017-09-01 2025-02-24 Novozymes A/S Dodatki paszowe dla zwierząt zawierające polipeptyd o aktywności proteazy i ich zastosowania
WO2019063613A1 (en) 2017-09-26 2019-04-04 Dsm Ip Assets B.V. ENZYMATIC ELIMINATION OF CHLOROPHYLL SUBSTRATES FROM TRIACYLGLYCEROL OILS
BR112020006224A2 (pt) 2017-09-27 2020-10-13 Novozymes A/S variantes de lipase e composições de microcápsulas compreendendo tais variantes de lipase
US11634673B2 (en) * 2017-09-29 2023-04-25 Dupont Nutrition Biosciences Aps Production of brewer's wort having increase fermentable sugars for fermentation
EP3692148A1 (en) 2017-10-02 2020-08-12 Novozymes A/S Polypeptides having mannanase activity and polynucleotides encoding same
CN111417725A (zh) 2017-10-02 2020-07-14 诺维信公司 具有甘露聚糖酶活性的多肽和编码它们的多核苷酸
EP3701016A1 (en) 2017-10-27 2020-09-02 Novozymes A/S Dnase variants
PL3476935T3 (pl) 2017-10-27 2022-03-28 The Procter & Gamble Company Kompozycje detergentowe zawierające odmiany polipeptydowe
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
US20200318086A1 (en) 2017-11-10 2020-10-08 Novozymes A/S Temperature-sensitive cas9 protein
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
EP3485734A1 (en) 2017-11-21 2019-05-22 Technische Universität München Method for preparing food products comprising rye
EP3488854A1 (en) 2017-11-22 2019-05-29 Technische Universität München Method for preparing xyloglucan-oligosaccharides
EP3720954A1 (en) 2017-12-04 2020-10-14 Novozymes A/S Lipase variants and polynucleotides encoding same
EP3502242A1 (en) 2017-12-20 2019-06-26 Technische Universität München New xylanase with improved thermostability and increased enzyme activity on arabinoxylan
US20210017544A1 (en) 2017-12-22 2021-01-21 Novozymes A/S Counter-Selection by Inhibition of Conditionally Essential Genes
KR101992345B1 (ko) * 2017-12-29 2019-09-27 (주)메디톡스 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도
WO2019154951A1 (en) 2018-02-08 2019-08-15 Novozymes A/S Lipases, lipase variants and compositions thereof
US20210071157A1 (en) 2018-02-08 2021-03-11 Novozymes A/S Lipase Variants and Compositions Thereof
US11667922B2 (en) 2018-03-26 2023-06-06 Novozymes A/S Fungal chaperone proteins
CN112105729B (zh) 2018-04-09 2024-05-14 诺维信公司 具有α-淀粉酶活性的多肽以及编码它们的多核苷酸
EP3781679A1 (en) 2018-04-19 2021-02-24 Novozymes A/S Stabilized cellulase variants
WO2019201785A1 (en) 2018-04-19 2019-10-24 Novozymes A/S Stabilized cellulase variants
CN112135903A (zh) 2018-05-18 2020-12-25 帝斯曼知识产权资产管理有限公司 突变体脂肪酶及其用途
WO2019219904A2 (en) 2018-05-18 2019-11-21 Dsm Ip Assets B.V. Mutant lipase and use thereof
WO2020002575A1 (en) 2018-06-28 2020-01-02 Novozymes A/S Polypeptides having pectin lyase activity and polynucleotides encoding same
CN112585267B (zh) 2018-08-02 2024-07-12 诺维信公司 使用内含子制备dna构建体的组合文库
WO2020043836A1 (en) 2018-08-31 2020-03-05 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP3861008A1 (en) 2018-10-03 2021-08-11 Novozymes A/S Polypeptides having alpha-mannan degrading activity and polynucleotides encoding same
CN113056552A (zh) 2018-10-09 2021-06-29 诺维信公司 经修饰的丝状真菌宿主细胞
US20220010305A1 (en) 2018-10-31 2022-01-13 Novozymes A/S Genome Editing by Guided Endonuclease and Single-stranded Oligonucleotide
BR112021010338A2 (pt) 2018-11-28 2021-11-16 Novozymes As Células hospedeiras fúngicas filamentosas modificadas
CN113166211A (zh) 2018-11-28 2021-07-23 诺维信公司 改善的丝状真菌宿主细胞
EP3894551A1 (en) 2018-12-12 2021-10-20 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
CN109652417B (zh) * 2018-12-17 2021-07-27 江南大学 一种构建高效枯草芽孢杆菌启动子的方法
CN113366103A (zh) 2018-12-21 2021-09-07 诺维信公司 具有肽聚糖降解活性的多肽以及编码其的多核苷酸
FI3898985T3 (fi) 2018-12-21 2023-05-05 Novozymes As Proteiinien tandemekspressio
US12371722B2 (en) 2019-01-11 2025-07-29 River Stone Biotech Aps Recombinant host cells with improved production of L-DOPA, dopamine, S-noroclaurine or derivatives thereof
WO2020161354A1 (en) 2019-02-08 2020-08-13 Pili Recombinant host cells to produce anthraquinone derivatives
WO2020173817A1 (en) 2019-02-28 2020-09-03 Novozymes A/S Calcite binding proteins
US10995325B2 (en) 2019-03-21 2021-05-04 Fornia Biosolutions, Inc. Additional phytase variants and methods
EP3946720A1 (en) 2019-03-27 2022-02-09 Bunge Global Innovation, LLC. Silica adsorbent treatment for removal of chlorophyll derivatives from triacylglycerol-based oils
BR112021019809A2 (pt) 2019-04-03 2021-12-07 Novozymes As Polipeptídeos que têm atividade de beta-glucanase, polinucleotídeos que codificam os mesmos e seus usos em composições de limpeza e de detergentes
CN113874499B (zh) 2019-04-10 2025-01-14 诺维信公司 多肽变体
EP3953463B1 (en) 2019-04-12 2025-08-06 Novozymes A/S Stabilized glycoside hydrolase variants
CN113939588A (zh) 2019-05-15 2022-01-14 诺维信公司 温度敏感性的rna指导的内切核酸酶
EP3976769A1 (en) 2019-05-27 2022-04-06 Octarine Bio IVS Genetically modified host cells producing glycosylated cannabinoids
US20220251528A1 (en) 2019-06-24 2022-08-11 Novozymes A/S Alpha-Amylase Variants
WO2020264552A1 (en) 2019-06-24 2020-12-30 The Procter & Gamble Company Cleaning compositions comprising amylase variants
WO2020260061A1 (en) 2019-06-25 2020-12-30 Novozymes A/S Counter-selection by inhibition of conditionally essential genes
WO2021001400A1 (en) 2019-07-02 2021-01-07 Novozymes A/S Lipase variants and compositions thereof
US20220267783A1 (en) 2019-07-25 2022-08-25 Novozymes A/S Filamentous fungal expression system
US20220251581A1 (en) 2019-07-26 2022-08-11 Novozymes A/S Modified filamentous fungal host cell
US20220331377A1 (en) 2019-09-09 2022-10-20 River Stone Biotech Isg Aps Delivery vehicle for in situ delivering of pharmaceutical agents
MX2022002834A (es) 2019-09-16 2022-04-06 Novozymes As Polipeptidos con actividad beta-glucanasa y polinucleotidos que los codifican.
WO2021064068A1 (en) 2019-10-03 2021-04-08 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
CN114761551B (zh) 2019-12-19 2025-09-12 诺维信公司 木聚糖酶变体和编码其的多核苷酸
WO2021123307A2 (en) 2019-12-20 2021-06-24 Novozymes A/S Polypeptides having proteolytic activity and use thereof
WO2021148278A1 (en) 2020-01-24 2021-07-29 Novozymes A/S Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide
EP4097227A1 (en) 2020-01-31 2022-12-07 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2021152120A1 (en) 2020-01-31 2021-08-05 Novozymes A/S Mannanase variants and polynucleotides encoding same
US20230235367A1 (en) 2020-02-10 2023-07-27 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
EP4103709A2 (en) 2020-02-10 2022-12-21 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
MX2022009515A (es) 2020-02-10 2022-09-02 Novozymes As Variantes de alfa-amilasa y polinucleotidos que las codifican.
EP4110909A1 (en) 2020-02-26 2023-01-04 Novozymes A/S Polypeptide variants
WO2021183622A1 (en) 2020-03-12 2021-09-16 Novozymes A/S Crispr-aid using catalytically inactive rna-guided endonuclease
EP3892708A1 (en) 2020-04-06 2021-10-13 Henkel AG & Co. KGaA Cleaning compositions comprising dispersin variants
CN115210371A (zh) 2020-04-08 2022-10-18 诺维信公司 碳水化合物结合模块变体
US20230167384A1 (en) 2020-04-21 2023-06-01 Novozymes A/S Cleaning compositions comprising polypeptides having fructan degrading activity
MX2023001888A (es) 2020-08-25 2023-03-10 Novozymes As Variantes de una xiloglucanasa de la familia 44.
EP4204548A1 (en) 2020-08-28 2023-07-05 Novozymes A/S Polyester degrading protease variants
US20230407273A1 (en) 2020-10-13 2023-12-21 Novozymes A/S Glycosyltransferase variants for improved protein production
US20240035005A1 (en) 2020-10-29 2024-02-01 Novozymes A/S Lipase variants and compositions comprising such lipase variants
EP4237555A1 (en) 2020-11-02 2023-09-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
CN116583534A (zh) 2020-11-02 2023-08-11 诺维信公司 前导肽和编码其的多核苷酸
US12071644B2 (en) 2020-12-17 2024-08-27 Fornia Biosolutions, Inc. Xylanase variants and methods
AR124921A1 (es) 2021-02-18 2023-05-17 Novozymes As Polipéptidos inactivos que contienen hemo
US20240301328A1 (en) 2021-03-12 2024-09-12 Novozymes A/S Polypeptide variants
WO2022197512A1 (en) 2021-03-15 2022-09-22 The Procter & Gamble Company Cleaning compositions containing polypeptide variants
EP4060036A1 (en) 2021-03-15 2022-09-21 Novozymes A/S Polypeptide variants
US20240060061A1 (en) 2021-03-15 2024-02-22 Novozymes A/S Dnase variants
AU2022270929A1 (en) 2021-05-07 2023-10-19 River Stone Biotech Aps Glycosylated opioids
EP4347813A1 (en) 2021-05-27 2024-04-10 Novozymes A/S Transcriptional regulators and polynucleotides encoding the same
WO2022268885A1 (en) 2021-06-23 2022-12-29 Novozymes A/S Alpha-amylase polypeptides
WO2023006699A1 (en) 2021-07-30 2023-02-02 Københavns Universitet Cells and method for producing isoprenoid molecules with canonical and non-canonical structures
EP4615963A1 (en) 2022-11-08 2025-09-17 River Stone Biotech ApS Genetically modified benzylisoquinoline alkaloid-producing host cells with modified efflux transporter gene expression

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
EP0305216B1 (en) 1987-08-28 1995-08-02 Novo Nordisk A/S Recombinant Humicola lipase and process for the production of recombinant humicola lipases
BR9106839A (pt) 1990-09-13 1993-07-20 Novo Nordisk As Variante de lipase,construcao de dna,vetor de expressao de recombinante,celula,planta,processo para produzir uma variante de lipase,aditivo e composicao de detergente
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
GB9316883D0 (en) * 1993-08-13 1993-09-29 Univ Leeds Production of heterologous peptices
CN1192108C (zh) 1994-06-03 2005-03-09 诺沃奇梅兹生物技术有限公司 纯化的毁丝霉属漆酶及编码该酶的核酸
WO1996000787A1 (en) * 1994-06-30 1996-01-11 Novo Nordisk Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
EP0877801B1 (en) 1996-01-19 2005-04-27 Novozymes Biotech, Inc. Morphological mutants of filamentous fungi
CN1190673A (zh) * 1996-04-29 1998-08-19 中国科学院微生物研究所 丝状真菌中独立复制的表达载体及表达系统
EP0966521A1 (en) 1996-09-13 1999-12-29 Novo Nordisk Biotech, Inc. Cells having dna insertion mutations which produce altered amounts of a polypeptide
AU5309698A (en) 1996-12-20 1998-07-17 Novo Nordisk A/S Peniophora phytase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
WO,A,9505474 1995.02.23
WO,A,9600787 1996.01.11

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