JP4620253B2 - 菌類細胞中で遺伝子を発現させるためのプロモーター - Google Patents
菌類細胞中で遺伝子を発現させるためのプロモーター Download PDFInfo
- Publication number
- JP4620253B2 JP4620253B2 JP2000606759A JP2000606759A JP4620253B2 JP 4620253 B2 JP4620253 B2 JP 4620253B2 JP 2000606759 A JP2000606759 A JP 2000606759A JP 2000606759 A JP2000606759 A JP 2000606759A JP 4620253 B2 JP4620253 B2 JP 4620253B2
- Authority
- JP
- Japan
- Prior art keywords
- seq
- promoter
- nucleic acid
- polypeptide
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 125000003729 nucleotide group Chemical group 0.000 claims 10
- 150000007523 nucleic acids Chemical group 0.000 claims 9
- 239000002773 nucleotide Substances 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 230000037430 deletion Effects 0.000 claims 3
- 238000012217 deletion Methods 0.000 claims 3
- 238000006467 substitution reaction Methods 0.000 claims 3
- 108020004414 DNA Proteins 0.000 claims 2
- 241000588724 Escherichia coli Species 0.000 claims 2
- 230000002538 fungal effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000013612 plasmid Substances 0.000 claims 2
- 230000003796 beauty Effects 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 238000003259 recombinant expression Methods 0.000 claims 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27444999A | 1999-03-22 | 1999-03-22 | |
| US09/274,449 | 1999-03-22 | ||
| PCT/US2000/007815 WO2000056900A2 (en) | 1999-03-22 | 2000-03-22 | Promoter sequences derived from fusarium venenatum and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010109995A Division JP5264825B2 (ja) | 1999-03-22 | 2010-05-12 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002539793A JP2002539793A (ja) | 2002-11-26 |
| JP2002539793A5 JP2002539793A5 (enExample) | 2007-05-17 |
| JP4620253B2 true JP4620253B2 (ja) | 2011-01-26 |
Family
ID=23048245
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000606759A Expired - Fee Related JP4620253B2 (ja) | 1999-03-22 | 2000-03-22 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
| JP2010109995A Expired - Fee Related JP5264825B2 (ja) | 1999-03-22 | 2010-05-12 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
| JP2013021124A Pending JP2013121360A (ja) | 1999-03-22 | 2013-02-06 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
| JP2013021169A Ceased JP2013121361A (ja) | 1999-03-22 | 2013-02-06 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010109995A Expired - Fee Related JP5264825B2 (ja) | 1999-03-22 | 2010-05-12 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
| JP2013021124A Pending JP2013121360A (ja) | 1999-03-22 | 2013-02-06 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
| JP2013021169A Ceased JP2013121361A (ja) | 1999-03-22 | 2013-02-06 | 菌類細胞中で遺伝子を発現させるためのプロモーター |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP1194572A2 (enExample) |
| JP (4) | JP4620253B2 (enExample) |
| CN (5) | CN100532561C (enExample) |
| AU (1) | AU4025700A (enExample) |
| DK (1) | DK2278016T3 (enExample) |
| WO (1) | WO2000056900A2 (enExample) |
Families Citing this family (493)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7883872B2 (en) | 1996-10-10 | 2011-02-08 | Dyadic International (Usa), Inc. | Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose |
| ATE286136T1 (de) | 1998-10-06 | 2005-01-15 | Mark Aaron Emalfarb | Transformationsystem in filamentösen fungiziden chrysosporium-wirtszellen |
| DE10036491A1 (de) * | 2000-07-25 | 2002-02-07 | Roche Diagnostics Gmbh | Expression von Alkalischer Phosphatase in Hefe |
| US7063962B2 (en) * | 2001-07-20 | 2006-06-20 | Novozymes A/S | DNA sequences for regulating transcription |
| AUPR945901A0 (en) | 2001-12-13 | 2002-01-24 | Macquarie University | Gene promoters |
| ATE542913T1 (de) | 2002-11-18 | 2012-02-15 | Novozymes Inc | Promotorvarianten zur expression von genen in einer pilzzelle |
| DK1613761T3 (da) | 2003-03-31 | 2009-12-14 | Novozymes Inc | Fremgangsmåder til fremstilling af biologiske stoffer i enzymdefekte mutanter af Aspergillus niger |
| DK1682656T3 (da) | 2003-10-28 | 2013-11-18 | Novozymes Inc | Polypeptider med beta-glucosidaseaktivitet og polynukleotider, der koder for dem |
| DK1713825T3 (da) | 2004-01-30 | 2012-11-05 | Novozymes Inc | Polypeptider med cellulolytisk forøgende aktivitet og polynukleotider der koder for samme |
| WO2006078256A2 (en) | 2004-02-12 | 2006-07-27 | Novozymes, Inc. | Polypeptides having xylanase activity and polynucleotides encoding same |
| PT3219806T (pt) | 2004-03-25 | 2020-06-30 | Novozymes Inc | Métodos para degradar ou converter polissacarídeos da parede celular de plantas |
| WO2005121351A2 (en) | 2004-05-27 | 2005-12-22 | Novozymes, Inc. | Methods for transforming and expression screening of filamentous fungal cells with a dna library |
| WO2006005032A2 (en) | 2004-06-29 | 2006-01-12 | Novozymes, Inc. | Polypeptides having alpha-glucosidase activity and polynucleotides encoding same |
| CN1308452C (zh) * | 2004-09-14 | 2007-04-04 | 上海永业农科生物工程有限公司 | 一种含有改组乙醇氧化酶启动子的毕赤酵母植酸酶表达系统 |
| US7666630B2 (en) | 2004-09-30 | 2010-02-23 | Novozymes, Inc. | Polypeptides having lipase activity and polynucleotides encoding same |
| EP1809747B1 (en) | 2004-10-04 | 2016-12-14 | Novozymes A/S | Polypeptides having phytase activity and polynucleotides encoding same |
| AR050895A1 (es) | 2004-10-04 | 2006-11-29 | Novozymes As | Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican |
| EP1814996A2 (en) | 2004-11-19 | 2007-08-08 | Novozymes A/S | Polypeptides having antimicrobial activity and polynucleotides encoding same |
| MX2007007107A (es) | 2004-12-22 | 2007-08-08 | Novozymes North America Inc | Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que los codifican. |
| CN106397601A (zh) * | 2004-12-22 | 2017-02-15 | 诺维信公司 | 用于淀粉加工的酶 |
| EP1861421B1 (en) | 2005-03-16 | 2011-10-19 | Novozymes Adenium Biotech A/S | Recombinant expression of insect defensins in Aspergillus |
| AU2006226729B2 (en) | 2005-03-22 | 2012-02-16 | Novozymes A/S | Polypeptides and nucleic acids encoding same |
| CA2606475C (en) | 2005-04-27 | 2015-06-16 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| AU2006283904B2 (en) | 2005-08-26 | 2012-07-12 | Novozymes Adenium Biotech A/S | Polypeptides having antimicrobial activity and polynucleotides encoding same |
| EP1941023B1 (en) | 2005-09-30 | 2017-04-05 | Novozymes Inc. | Methods for enhancing the degradation or conversion of cellulosic material |
| DK1941025T3 (da) | 2005-10-17 | 2011-09-26 | Novozymes As | Brug af svampemutanter til ekspression af antistoffer |
| US8262646B2 (en) * | 2006-01-20 | 2012-09-11 | Lensar, Inc. | System and method for providing the shaped structural weakening of the human lens with a laser |
| EP1999257B1 (en) | 2006-03-20 | 2011-06-22 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| EP2004817A2 (en) | 2006-03-30 | 2008-12-24 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| CN101512001A (zh) | 2006-07-14 | 2009-08-19 | 诺维信股份有限公司 | 提高真菌细胞中基因表达的方法 |
| WO2008008950A2 (en) | 2006-07-14 | 2008-01-17 | Novozymes, Inc. | Methods for producing secreted polypeptides having biological activity |
| WO2008057637A2 (en) | 2006-07-21 | 2008-05-15 | Novozymes, Inc. | Methods of increasing secretion of polypeptides having biological activity |
| EP2431470B1 (en) | 2006-11-30 | 2017-11-29 | Novozymes A/S | Dnase expression in recombinant host cells |
| EP2505651A3 (en) | 2006-12-10 | 2013-01-09 | Dyadic International, Inc. | Isolated fungus with reduced protease activity |
| PL3101128T3 (pl) | 2006-12-21 | 2019-09-30 | Basf Enzymes Llc | Amylazy i glukoamylazy, kwasy nukleinowe kodujące te związki oraz sposoby wytwarzania tych związków oraz stosowania ich |
| DK2129781T3 (da) | 2007-03-26 | 2014-03-31 | Novozymes As | Hafnia-phytase |
| DE102007016139A1 (de) | 2007-03-30 | 2008-10-02 | Jenabios Gmbh | Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen |
| EP2594583A1 (en) | 2007-08-08 | 2013-05-22 | Novozymes Biopharma DK A/S | Transferrin variants and conugates |
| JP5769142B2 (ja) * | 2007-09-04 | 2015-08-26 | 独立行政法人酒類総合研究所 | ピヒア属酵母において異種タンパク質を高分泌させる方法 |
| WO2009033071A2 (en) | 2007-09-07 | 2009-03-12 | Dyadic International, Inc. | Novel fungal enzymes |
| EP2193195B1 (en) | 2007-09-18 | 2014-12-17 | Novozymes A/S | Polypeptides having tyrosinase activity and polynucleotides encoding same |
| US7867745B2 (en) | 2007-11-27 | 2011-01-11 | Novozymes A/S | Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same |
| ES2490608T3 (es) | 2007-12-06 | 2014-09-04 | Novozymes A/S | Polipéptidos con actividad de esterasa de acetilxilano y polinucleótidos que codifican los mismos |
| EP2235173A2 (en) | 2007-12-19 | 2010-10-06 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2010059413A2 (en) | 2008-11-20 | 2010-05-27 | Novozymes, Inc. | Polypeptides having amylolytic enhancing activity and polynucleotides encoding same |
| US7771983B2 (en) | 2008-12-04 | 2010-08-10 | Novozymos, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2010068800A1 (en) | 2008-12-12 | 2010-06-17 | Novozymes, Inc. | Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same |
| US20110296557A1 (en) | 2008-12-12 | 2011-12-01 | Novozymes, Inc. | Polypeptides Having Lipase Activity And Polynucleotides Encoding Same |
| WO2010074972A1 (en) | 2008-12-15 | 2010-07-01 | Novozymes, Inc. | Polypeptides having catalase activity and polynucleotides encoding same |
| WO2010074955A1 (en) | 2008-12-16 | 2010-07-01 | Novozymes, Inc. | Polypeptides having carboxypeptidase activity and polynucleotides encoding same |
| US20110271407A1 (en) | 2008-12-16 | 2011-11-03 | Novozymes, Inc. | Polypeptides Having Alpha-Mannosidase Activity And Polynucleotides Encoding Same |
| CN107190030A (zh) | 2008-12-19 | 2017-09-22 | 诺维信股份有限公司 | 在纤维二糖脱氢酶存在下增加纤维素材料水解的方法 |
| US8338121B2 (en) | 2008-12-19 | 2012-12-25 | Novozymes, Inc. | Methods for determining cellulolytic enhancing activity of a polypeptide |
| CA2747056A1 (en) | 2008-12-19 | 2010-07-15 | Novozymes, Inc. | Methods for increasing enzymatic hydrolysis of cellulosic material in the presence of a peroxidase |
| EP2379733A2 (en) | 2008-12-19 | 2011-10-26 | Novozymes Inc. | Methods for increasing hydrolysis of cellulosic material |
| EP3444343B1 (en) | 2008-12-23 | 2020-10-28 | DuPont Nutrition Biosciences ApS | Polypeptides |
| CN102361973B (zh) | 2009-01-21 | 2015-09-02 | 诺维信公司 | 具有酯酶活性的多肽和编码该多肽的核酸 |
| WO2010088387A1 (en) | 2009-01-28 | 2010-08-05 | Novozymes, Inc. | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| WO2010088463A2 (en) | 2009-01-30 | 2010-08-05 | Novozymes, Inc. | Polypeptides having expansin activity and polynucleotides encoding same |
| WO2010088447A1 (en) | 2009-01-30 | 2010-08-05 | Novozymes A/S | Polypeptides having alpha-amylase activity and polynucleotides encoding same |
| WO2010091221A1 (en) | 2009-02-06 | 2010-08-12 | Novozymes A/S | Polypeptides having alpha-amylase activity and polynucleotides encoding same |
| US20110294988A1 (en) | 2009-02-06 | 2011-12-01 | Novozymes Bio Pharma DK A/S | Purification Process |
| SG172789A1 (en) | 2009-02-11 | 2011-08-29 | Novozymes Biopharma Dk As | Albumin variants and conjugates |
| EP2408314A1 (en) | 2009-03-17 | 2012-01-25 | Novozymes A/S | Polypeptides having tyrosinase activity and polynucleotides encoding same |
| CN102365360A (zh) | 2009-03-24 | 2012-02-29 | 诺维信公司 | 具有乙酰木聚糖酯酶活性的多肽和编码该多肽的多核苷酸 |
| EP2248893A1 (en) | 2009-05-06 | 2010-11-10 | Novozymes A/S | DFPase Enzymes from Octopus Vulgaris |
| EP2435561B1 (en) | 2009-05-29 | 2018-08-08 | Novozymes Inc. | Methods for enhancing the degradation or conversion of cellulosic material |
| ES2534078T3 (es) | 2009-06-02 | 2015-04-17 | Novozymes Inc. | Polipéptidos con actividad de celobiohidrolasa y polinucleótidos que codifican los mismos |
| WO2010151787A1 (en) | 2009-06-26 | 2010-12-29 | Novozymes North America, Inc. | Heat-stable carbonic anhydrases and their use |
| CA2767169A1 (en) | 2009-07-07 | 2011-01-13 | Novozymes, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| MX2012001060A (es) | 2009-07-24 | 2012-03-14 | Novozymes As | Carbohidrato-oxidasas. |
| WO2011014458A1 (en) | 2009-07-28 | 2011-02-03 | Novozymes, Inc. | Polypeptides having phytase activity and polynucleotides encoding same |
| CN102498126A (zh) | 2009-08-07 | 2012-06-13 | 诺维信公司 | 用于产生甜蛋白的方法 |
| US8409830B2 (en) | 2009-08-21 | 2013-04-02 | Novozymes A/S | Polypeptides having isoamylase activity and methods of use |
| US8741611B2 (en) | 2009-09-01 | 2014-06-03 | Novozymes, Inc. | Methods for improving malic acid production in filamentous fungi |
| DK3269804T3 (da) | 2009-09-17 | 2020-11-23 | Novozymes Inc | Polypeptider med cellulolyseforbedrende aktivitet og polynukleotider, som koder for dem |
| EP2478095A1 (en) | 2009-09-18 | 2012-07-25 | Novozymes Inc. | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| EP2480650B1 (en) | 2009-09-25 | 2017-03-22 | Novozymes A/S | Subtilase variants |
| CN102648277B (zh) | 2009-09-25 | 2015-05-20 | 诺维信公司 | 蛋白酶变体的用途 |
| WO2011041397A1 (en) | 2009-09-29 | 2011-04-07 | Novozymes, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| CA2775347A1 (en) | 2009-09-29 | 2011-04-07 | Novozymes A/S | Polypeptides having xylanase activity and polynucleotides encoding same |
| BR112012007375A2 (pt) | 2009-09-30 | 2016-11-22 | Novozymes As | polipeptídeo isolado, polinucleotídeo isolado, métodos para produzir um polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação e para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta transformada, molécula de rna inibitória de filamento duplo, e, composição detergente |
| WO2011039319A1 (en) | 2009-09-30 | 2011-04-07 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2011050037A1 (en) | 2009-10-23 | 2011-04-28 | Novozymes, Inc. | Cellobiohydrolase variants and polynucleotides encoding same |
| WO2011059740A1 (en) | 2009-10-29 | 2011-05-19 | Novozymes, Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| DK2496692T3 (en) | 2009-11-06 | 2016-06-27 | Novozymes Inc | POLYPEPTIDES WITH xylanase AND POLYNUCLEOTIDES ENCODING THEM |
| DK3222716T3 (da) | 2009-11-06 | 2020-11-16 | Novozymes Inc | Sammensætninger til saccharificering af cellulosemateriale |
| CN103068976A (zh) | 2009-11-06 | 2013-04-24 | 诺维信股份有限公司 | 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸 |
| CA2782154C (en) * | 2009-11-30 | 2018-10-16 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| CN102869770B (zh) | 2009-11-30 | 2015-12-16 | 诺维信公司 | 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸 |
| CA2782036C (en) | 2009-12-01 | 2019-01-15 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| WO2011067349A1 (en) | 2009-12-03 | 2011-06-09 | Novozymes A/S | Variants of a polypeptide with lipolytic activity and improved stability |
| US8951770B2 (en) | 2009-12-09 | 2015-02-10 | Novozymes A/S | GH8 xylanase variants |
| MX350399B (es) | 2009-12-18 | 2017-09-06 | Novozymes Inc | Metodos para producir polipeptidos en mutantes de trichoderma deficientes en proteasa. |
| US20120220513A1 (en) | 2009-12-29 | 2012-08-30 | Novozymes A/S | Polypeptides Having Detergency Enhancing Effect |
| CN102884183B (zh) | 2010-01-04 | 2015-09-16 | 诺维信公司 | 趋于钙耗竭和酸性pH的α-淀粉酶的稳定化 |
| WO2011104284A1 (en) | 2010-02-25 | 2011-09-01 | Novozymes A/S | Polypeptides having antimicrobial activity |
| WO2011109524A2 (en) | 2010-03-03 | 2011-09-09 | Novozymes, Inc. | Xylanase variants and polynucleotides encoding same |
| WO2011123450A1 (en) | 2010-03-31 | 2011-10-06 | Novozymes, Inc. | Cellobiohydrolase variants and polynucleotides encoding same |
| CA2795806C (en) | 2010-04-14 | 2019-01-08 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| WO2011153317A1 (en) | 2010-06-04 | 2011-12-08 | Novozymes, Inc. | C4 dicarboxylic acid production in filamentous fungi |
| US8835604B2 (en) | 2010-06-12 | 2014-09-16 | Adenium Biotech Aos | Antimicrobial peptide variants and polynucleotides encoding same |
| IN2013CN00459A (enExample) | 2010-06-21 | 2015-07-03 | Novozymes Inc | |
| AU2011271094B2 (en) | 2010-06-21 | 2015-01-22 | Novozymes, Inc. | Aspergillus aculeatus derived polypeptides having C4-dicarboxylic acid transporter activity and polynucleotides encoding same |
| WO2011161206A1 (en) | 2010-06-25 | 2011-12-29 | Novozymes A/S | Polynucleotides having leader sequence function |
| EP2588604B1 (en) | 2010-06-30 | 2016-06-29 | Novozymes, Inc. | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| CA2803222A1 (en) | 2010-07-01 | 2012-01-05 | Dsm Ip Assets B.V. | A method for the production of a compound of interest |
| WO2012021401A1 (en) | 2010-08-12 | 2012-02-16 | Novozymes, Inc. | Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicyclic compound and uses thereof |
| CN107299095B (zh) | 2010-08-24 | 2021-05-11 | 诺维信公司 | 热稳定性Persephonella碳酸酐酶及其用途 |
| US8629325B2 (en) | 2010-08-30 | 2014-01-14 | Novozymes A/S | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| WO2012030811A1 (en) | 2010-08-30 | 2012-03-08 | Novozymes A/S | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| US9267126B2 (en) | 2010-08-30 | 2016-02-23 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| WO2012030849A1 (en) | 2010-08-30 | 2012-03-08 | Novozymes A/S | Polypeptides having xylanase activity and polynucleotides encoding same |
| US9303074B2 (en) | 2010-08-30 | 2016-04-05 | Novoyzmes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2012030858A2 (en) | 2010-08-30 | 2012-03-08 | Novozymes A/S | Polypeptides having hemicellulolytic activity and polynucleotides encoding same |
| EP2622070B1 (en) | 2010-09-30 | 2016-08-03 | Novozymes, Inc. | Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| EP2622068B1 (en) | 2010-09-30 | 2016-07-20 | Novozymes, Inc. | Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| RU2583293C2 (ru) | 2010-10-01 | 2016-05-10 | Новозимс А/С | Полипептиды, обладающие эндопептидазной активностью, и кодирующие их полинуклеотиды |
| MX2013002586A (es) | 2010-10-01 | 2013-03-21 | Novozymes Inc | Variantes de beta-glucosidasa y polinucleotidos que codifican las mismas. |
| WO2012058293A1 (en) | 2010-10-26 | 2012-05-03 | Novozymes North America, Inc. | Methods of saccharifying sugarcane trash |
| EP2632943A1 (en) | 2010-10-29 | 2013-09-04 | Novozymes A/S | Polypeptides having succinyl-coa:aceto acetate transferase activity and polynucleotides encoding same |
| MX2013004353A (es) | 2010-10-29 | 2013-06-28 | Novozymes Inc | Produccion recombinante de n-propanol e isopropanol. |
| DK2635689T3 (en) | 2010-11-02 | 2015-07-06 | Novozymes Inc | METHODS OF PREPARATION OF cellulosic material WITH A GH61-POLYPEPTIDE |
| EP2635594B1 (en) | 2010-11-04 | 2017-01-11 | Novozymes Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| EP2637515B1 (en) | 2010-11-08 | 2017-09-06 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| DK2638154T3 (da) | 2010-11-08 | 2017-01-02 | Novozymes As | Polypeptider med glucoamylaseaktivitet og polynukleotider, der koder for dem |
| BR112013009026A2 (pt) | 2010-11-12 | 2016-07-12 | Novozymes Inc | polipeptídeo isolado, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, uma proteína, e um produto de fermentação, para inibir a expressão de um polipeptídeo, para degradar ou converter um material celulósico, e método para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo, polinucleotídeo isolado, e, formulação de caldo integral ou composição de cultura de célula |
| BR112013011442A2 (pt) | 2010-11-12 | 2020-08-11 | Novozymes A/S | polipeptídeo isolado, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, método de produção do polipeptídeo, composição, uso do polipeptídeo ou da composição, métodos de redução do teor de componentes contendo fósforo em um óleo comestível, e para desengomagem de uma composição de óleo |
| WO2012068509A1 (en) | 2010-11-18 | 2012-05-24 | Novozymes, Inc. | Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| DK2646558T3 (en) | 2010-11-30 | 2016-10-03 | Novozymes Inc | Promoters for expression of genes in a fungal cell |
| US8927235B2 (en) | 2010-12-06 | 2015-01-06 | Novozymes A/S | Methods of hydrolyzing oligomers in hemicellulosic liquor |
| AU2011338504B2 (en) | 2010-12-07 | 2015-01-22 | Vnomics Corp. | System and method for measuring and reducing vehicle fuel waste |
| WO2012083081A1 (en) | 2010-12-16 | 2012-06-21 | Novozymes, Inc. | Promoters for expressing genes in a fungal cell |
| DK2668270T3 (en) | 2011-01-26 | 2019-01-07 | Novozymes Inc | Polypeptides with cellobiohydrolase activity and polynucleotides encoding them |
| MX2013007720A (es) | 2011-01-26 | 2013-08-09 | Novozymes As | Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos. |
| WO2012103322A1 (en) | 2011-01-26 | 2012-08-02 | Novozymes A/S | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| EP2668266B1 (en) | 2011-01-26 | 2018-01-03 | Novozymes A/S | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| US9157075B2 (en) | 2011-01-26 | 2015-10-13 | Novozymes, Inc. | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| DK2670853T3 (en) | 2011-01-31 | 2017-08-28 | Novozymes North America Inc | Process for enzymatic refining of pretreated cellulosic material for sugars |
| CN103797114A (zh) | 2011-02-23 | 2014-05-14 | 杜邦营养生物科学有限公司 | 生产能够水解叶绿素或叶绿素衍生物的重组酶的方法 |
| EP2678352B1 (en) | 2011-02-23 | 2017-12-06 | Novozymes, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2012118848A1 (en) | 2011-02-28 | 2012-09-07 | Novozymes, Inc. | Microorganism for c4-dicarboxylic acid production |
| CN103608461B (zh) | 2011-03-09 | 2016-08-03 | 诺维信公司 | 增加多肽的纤维素分解增强活性的方法 |
| WO2012122477A1 (en) | 2011-03-10 | 2012-09-13 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2012123429A1 (en) | 2011-03-11 | 2012-09-20 | Dsm Ip Assets B.V. | Vector-host system |
| US9879294B2 (en) | 2011-03-25 | 2018-01-30 | Novozymes A/S | Methods for degrading or converting cellulosic material |
| WO2012135719A1 (en) | 2011-03-31 | 2012-10-04 | Novozymes, Inc. | Cellulose binding domain variants and polynucleotides encoding same |
| WO2012135659A2 (en) | 2011-03-31 | 2012-10-04 | Novozymes A/S | Methods for enhancing the degradation or conversion of cellulosic material |
| DK2702153T3 (en) | 2011-04-28 | 2019-03-18 | Novozymes Inc | Polypeptides with endoglucanase activity and polynucleotides encoding them |
| DK2702162T3 (da) | 2011-04-29 | 2020-05-18 | Novozymes Inc | Fremgangsmåder til forbedring af nedbrydningen eller omdannelsen af celluloseholdigt materiale |
| EP2710132A1 (en) | 2011-05-19 | 2014-03-26 | Novozymes, Inc. | Methods for enhancing the degradation of cellulosic material with chitin binding proteins |
| EP2710133A1 (en) | 2011-05-19 | 2014-03-26 | Novozymes, Inc. | Methods for enhancing the degradation of cellulosic material with chitin binding proteins |
| EP2527448A1 (en) | 2011-05-23 | 2012-11-28 | Novozymes A/S | Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi |
| EP2527432A1 (en) | 2011-05-23 | 2012-11-28 | Novozymes A/S | Bi-directional cytosine deaminase-encoding selection marker |
| CN103620029B (zh) | 2011-06-24 | 2017-06-09 | 诺维信公司 | 具有蛋白酶活性的多肽和编码它们的多核苷酸 |
| EP3421595B1 (en) | 2011-06-30 | 2020-10-07 | Novozymes A/S | Alpha-amylase-variants |
| EP2726500B1 (en) | 2011-06-30 | 2019-03-20 | Novozymes A/S | Method for screening alpha-amylases |
| MX337984B (es) | 2011-07-06 | 2016-03-30 | Novozymes As | Variantes de alfa amilasa y polinucleotidos que codifican la misma. |
| CN103827298A (zh) | 2011-07-15 | 2014-05-28 | 诺维信公司 | 脂肪酶变体及其编码多核苷酸 |
| CN109022518A (zh) | 2011-07-22 | 2018-12-18 | 诺维信北美公司 | 用于预处理纤维素材料和改进其水解的方法 |
| EP2739728B1 (en) | 2011-08-04 | 2017-07-12 | Novozymes A/S | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| BR112014002401B1 (pt) | 2011-08-04 | 2021-08-03 | Novozymes A/S | Célula hospedeira transgênica de fungo filamentoso, métodos para produzir um polipeptídeo e uma proteína, e, construto de ácido nucleico ou um vetor de expressão |
| WO2013021062A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021065A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021059A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| EP2742129B1 (en) | 2011-08-10 | 2017-08-02 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9487761B2 (en) | 2011-08-10 | 2016-11-08 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9506044B2 (en) | 2011-08-10 | 2016-11-29 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013021064A1 (en) | 2011-08-10 | 2013-02-14 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| EP2744898A1 (en) | 2011-08-15 | 2014-06-25 | Novozymes A/S | Polypeptides having cellulase activity and polynucleotides encoding same |
| BR112014003444A2 (pt) | 2011-08-19 | 2017-03-14 | Novozymes Inc | célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico |
| US20140295027A1 (en) | 2011-08-19 | 2014-10-02 | Novozymes A/S | Polypeptides Having Protease Activity |
| DK2748305T3 (en) | 2011-08-24 | 2017-02-06 | Novozymes Inc | CELLULOLYTIC ENZYME COMPOSITIONS AND APPLICATIONS THEREOF |
| BR112014004188A2 (pt) | 2011-08-24 | 2017-03-21 | Novozymes Inc | método para obter transformantes positivos de uma célula hospedeira fúngica filamentosa, célula hospedeira fúngica filamentosa, método para produzir múltiplos polipeptídeos recombinantes, e, construto em tandem |
| WO2013028912A2 (en) | 2011-08-24 | 2013-02-28 | Novozymes, Inc. | Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell |
| EP2748314B1 (en) | 2011-08-24 | 2016-12-28 | Novozymes, Inc. | Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof |
| CA2846690A1 (en) | 2011-08-26 | 2013-03-07 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| CN103930543B (zh) | 2011-09-06 | 2020-11-27 | 诺维信公司 | 葡糖淀粉酶变体和编码它们的多核苷酸 |
| CA2847236A1 (en) | 2011-09-09 | 2013-03-14 | Novozymes A/S | Polypeptides having alpha-amylase activity and polynucleotides encoding same |
| EP2756091A1 (en) | 2011-09-13 | 2014-07-23 | Novozymes North America, Inc. | Methods of hydrolyzing and fermenting cellulosic material |
| US20140308705A1 (en) | 2011-09-20 | 2014-10-16 | Novozymes A/S | Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same |
| ES2628190T3 (es) | 2011-09-22 | 2017-08-02 | Novozymes A/S | Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos |
| EP2751261B1 (en) | 2011-09-30 | 2018-08-29 | Novozymes, Inc. | Dehydrogenase variants and polynucleotides encoding same |
| WO2013044867A1 (en) | 2011-09-30 | 2013-04-04 | Novozymes A/S | Polypeptides having alpha-amylase activity and polynucleotides encoding same |
| DK2760885T3 (en) | 2011-09-30 | 2017-10-30 | Novozymes Inc | CHEMICAL POLYPEPTIDES WITH BETA-GLUCOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM |
| US9353362B2 (en) | 2011-10-11 | 2016-05-31 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| HUE039835T2 (hu) | 2011-10-17 | 2019-02-28 | Novozymes As | Alfa-amiláz variánsok és az azokat kódoló polinukleotidok |
| CA3253390A1 (en) | 2011-10-17 | 2025-06-17 | Novozymes A/S | Variants of alpha-amylase and the polynucleotides encoding them |
| US10308921B2 (en) | 2011-10-31 | 2019-06-04 | Novozymes, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| EP2780449B1 (en) | 2011-11-18 | 2018-04-11 | Novozymes, Inc. | Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same |
| CN103958672A (zh) | 2011-11-21 | 2014-07-30 | 诺维信股份有限公司 | Gh61多肽变体以及编码所述变体的多核苷酸 |
| DK2782998T3 (en) | 2011-11-22 | 2018-04-16 | Novozymes Inc | POLYPEPTIDES WITH BETA-XYLOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM |
| JP6105615B2 (ja) | 2011-11-25 | 2017-03-29 | ノボザイムス アクティーゼルスカブ | リゾチーム活性を有するポリペプチドおよびそれをコードするポリヌクレオチド |
| US9624481B2 (en) | 2011-12-01 | 2017-04-18 | Novozymes, Inc. | Polypeptides having beta-xylosidase activity and polynucleotides encoding same |
| US9169469B2 (en) | 2011-12-02 | 2015-10-27 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| US9404093B2 (en) | 2011-12-02 | 2016-08-02 | Novozymes A/S | Polypeptides having peroxygenase activity and polynucleotides encoding same |
| WO2013087027A1 (en) | 2011-12-16 | 2013-06-20 | Novozymes, Inc. | Polypeptides having laccase activity and polynucleotides encoding same |
| WO2013091547A1 (en) | 2011-12-19 | 2013-06-27 | Novozymes, Inc. | Polypeptides having catalase activity and polynucleotides encoding same |
| DK2794869T3 (en) | 2011-12-20 | 2018-01-02 | Novozymes Inc | CELLOBIO HYDROLASE VARIABLES AND POLYNUCLEOTIDES CODING THEM |
| ES2667318T3 (es) | 2011-12-28 | 2018-05-10 | Novozymes A/S | Polipéptidos con actividad de proteasa |
| US9801398B2 (en) | 2012-01-26 | 2017-10-31 | Novozymes A/S | Use of polypeptides having protease activity in animal feed and detergents |
| DK2623586T3 (da) | 2012-02-03 | 2017-11-13 | Procter & Gamble | Sammensætninger og fremgangsmåder til overfladebehandling med lipaser |
| EP4570895A3 (en) | 2012-02-03 | 2026-01-14 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
| PT2817325T (pt) | 2012-02-20 | 2019-10-01 | Novozymes As | Polipéptidos que têm atividade da endoglucanase e polinucleotídeos codificando mesmos |
| EP2834353B1 (en) | 2012-04-02 | 2017-07-19 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
| US9446102B2 (en) | 2012-04-23 | 2016-09-20 | Novozymes A/S | Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same |
| EP2841570B1 (en) | 2012-04-23 | 2017-12-20 | Novozymes A/S | Polypeptides having glucuronyl esterase activity and polynucleotides encoding same |
| CN104245926B (zh) | 2012-04-27 | 2021-05-07 | 诺维信股份有限公司 | Gh61多肽变体以及编码其的多核苷酸 |
| CN113201519A (zh) | 2012-05-07 | 2021-08-03 | 诺维信公司 | 具有黄原胶降解活性的多肽以及编码其的核苷酸 |
| EP2855670A2 (en) | 2012-05-31 | 2015-04-08 | Novozymes A/S | Polypeptides having organophosphorous hydrolase activity |
| EP2855659A1 (en) | 2012-05-31 | 2015-04-08 | Novozymes A/S | Improved selection in fungi |
| MX364390B (es) | 2012-06-20 | 2019-04-25 | Novozymes As | Uso de polipeptidos que tienen actividad proteasa en alimentos para animales y detergentes. |
| CN104471048B (zh) | 2012-07-12 | 2018-11-16 | 诺维信公司 | 具有脂肪酶活性的多肽及编码它的多核苷酸 |
| EP3327112B1 (en) | 2012-07-19 | 2020-02-12 | DSM IP Assets B.V. | Agse-deficient strain |
| US9828595B2 (en) | 2012-08-17 | 2017-11-28 | Novozymes A/S | Thermostable asparaginase variants and polynucleotides encoding same |
| WO2014028833A1 (en) | 2012-08-17 | 2014-02-20 | Novozymes A/S | Methods for co-silencing expression of genes in filamentous fungal strains and uses thereof |
| US9315791B2 (en) | 2012-08-22 | 2016-04-19 | Novozymes A/S | Metalloproteases from alicyclobacillus |
| MX2015002211A (es) | 2012-08-22 | 2015-05-08 | Novozymes As | Metaloproteasa de exiguobacterium. |
| AU2013311668B2 (en) | 2012-09-05 | 2019-02-28 | Novozymes A/S | Polypeptides having protease activity |
| JP5971661B2 (ja) * | 2012-09-19 | 2016-08-17 | 国立大学法人 東京大学 | 神経活動依存的プロモータ活性を有するdna、及びこれを含むベクター |
| BR112015005884A2 (pt) | 2012-09-19 | 2017-08-08 | Novozymes Inc E Novozymes As | processos para degradação de um material celulósico, para produção de um produto da fermentação, e de fermentação de um material celulósico, composição, e, formulação de caldo inteiro ou composição de cultura de células |
| EP3586610B1 (en) | 2012-10-08 | 2024-09-25 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| EP2906686B1 (en) | 2012-10-12 | 2018-08-29 | Novozymes A/S | Polypeptides having peroxygenase activity |
| WO2014056916A2 (en) | 2012-10-12 | 2014-04-17 | Novozymes A/S | Polypeptides having peroxygenase activity |
| EP2906689B1 (en) | 2012-10-12 | 2018-12-12 | Novozymes A/S | Polypeptides having peroxygenase activity |
| EP2906685B1 (en) | 2012-10-12 | 2018-08-15 | Novozymes A/S | Polypeptides having peroxygenase activity |
| US9453207B2 (en) | 2012-10-12 | 2016-09-27 | Novozymes A/S | Polypeptides having peroxygenase activity |
| US9404094B2 (en) | 2012-10-12 | 2016-08-02 | Novozymes A/S | Polypeptides having peroxygenase activity |
| CN104718287B (zh) | 2012-10-12 | 2018-02-06 | 诺维信公司 | 具有过氧合酶活性的多肽 |
| WO2014066141A2 (en) | 2012-10-24 | 2014-05-01 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2014076232A2 (en) | 2012-11-19 | 2014-05-22 | Novozymes A/S | Isopropanol production by recombinant hosts using an hmg-coa intermediate |
| US20150307871A1 (en) | 2012-12-07 | 2015-10-29 | Novozymes A/S | Method for generating site-specific mutations in filamentous fungi |
| US20150368627A1 (en) | 2012-12-11 | 2015-12-24 | Novozymes A/S | Polypeptides Having Phospholipase C Activity and Polynucleotides Encoding Same |
| US9765373B2 (en) | 2012-12-14 | 2017-09-19 | Novozymes A/S | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| ES2772032T3 (es) | 2012-12-17 | 2020-07-07 | Novozymes As | Alfa-amilasas y polinucleótidos que las codifican |
| WO2014099798A1 (en) | 2012-12-19 | 2014-06-26 | Novozymes A/S | Polypeptides having cellulolytic enhancinc activity and polynucleotides encoding same |
| US9551042B2 (en) | 2012-12-21 | 2017-01-24 | Novozymes A/S | Polypeptides having protease activity and polynucleotides encoding same |
| EP2938628A4 (en) | 2012-12-24 | 2016-10-19 | Novozymes As | POLYPEPTIDES WITH ENDOGLUCANASE ACTIVITY AND POLYNUCLEOTIDES FOR CODING THEREOF |
| EP3321360A3 (en) | 2013-01-03 | 2018-06-06 | Novozymes A/S | Alpha-amylase variants and polynucleotides encoding same |
| EP3686280B1 (en) | 2013-02-04 | 2022-06-22 | DSM IP Assets B.V. | Carbohydrate degrading polypeptide and uses thereof |
| MX2015010078A (es) | 2013-02-06 | 2016-01-25 | Novozymes As | Uso de polipeptidos con actividad proteasa en alimentos para animales. |
| CN105164254B (zh) | 2013-03-08 | 2019-06-28 | 诺维信公司 | 纤维二糖水解酶变体和编码它们的多核苷酸 |
| WO2014145768A2 (en) | 2013-03-15 | 2014-09-18 | Bp Corporation North America Inc. | Use of non-fungal 5' utrs in filamentous fungi |
| EP3533866A1 (en) | 2013-03-21 | 2019-09-04 | Novozymes A/S | Polypeptides having phospholipase a activity and polynucleotides encoding same |
| US9631164B2 (en) | 2013-03-21 | 2017-04-25 | Novozymes A/S | Polypeptides with lipase activity and polynucleotides encoding same |
| WO2014170218A1 (en) | 2013-04-18 | 2014-10-23 | Novozymes A/S | Polypeptides having protease activity and polynucleotides encoding same |
| WO2014177541A2 (en) | 2013-04-30 | 2014-11-06 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| EP3372680B1 (en) | 2013-04-30 | 2020-11-11 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| US9556465B2 (en) | 2013-05-10 | 2017-01-31 | Novozymes A/S | Polypeptides having xylanase activity and polynucleotides encoding same |
| MX392247B (es) | 2013-05-14 | 2025-03-24 | Novozymes As | Composiciones detergentes. |
| US20160083703A1 (en) | 2013-05-17 | 2016-03-24 | Novozymes A/S | Polypeptides having alpha amylase activity |
| CN114634921B (zh) | 2013-06-06 | 2024-09-10 | 诺维信公司 | α-淀粉酶变体以及对其进行编码的多核苷酸 |
| WO2014202624A2 (en) | 2013-06-19 | 2014-12-24 | Dsm Ip Assets B.V. | Rasamsonia gene and use thereof |
| WO2014202622A2 (en) | 2013-06-19 | 2014-12-24 | Dsm Ip Assets B.V. | Rasamsonia gene and use thereof |
| WO2014202620A2 (en) | 2013-06-19 | 2014-12-24 | Dsm Ip Assets B.V. | Rasamsonia gene and use thereof |
| WO2014202621A1 (en) | 2013-06-20 | 2014-12-24 | Dsm Ip Assets B.V. | Carbohydrate degrading polypeptide and uses thereof |
| JP2016523098A (ja) | 2013-07-04 | 2016-08-08 | ノボザイムス アクティーゼルスカブ | 再付着防止効果を有するポリペプチドおよびそれをコードするポリヌクレオチド |
| WO2015004102A1 (en) | 2013-07-09 | 2015-01-15 | Novozymes A/S | Polypeptides with lipase activity and polynucleotides encoding same |
| DK3022300T3 (en) | 2013-07-17 | 2018-10-22 | Novozymes As | : Pullulan chimeras and polynucleotides encoding them |
| CA2917690A1 (en) | 2013-07-26 | 2015-01-29 | Biomethodes | Novel variant trichoderma reesei endoglucanases |
| CN104342419B (zh) * | 2013-08-06 | 2017-03-08 | 上海康地恩生物科技有限公司 | 一种来源于黑葡萄穗霉的葡糖淀粉酶 |
| US10010094B2 (en) | 2013-08-15 | 2018-07-03 | Novozymes A/S | Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same |
| WO2015059133A1 (en) | 2013-10-22 | 2015-04-30 | Novozymes A/S | Cellobiose dehydrogenase variants and polynucleotides encoding same |
| CN105518142B (zh) | 2013-10-25 | 2020-07-28 | 诺维信公司 | 具有内切葡聚糖酶活性的多肽以及对其进行编码的多核苷酸 |
| EP2876156A1 (en) | 2013-11-26 | 2015-05-27 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof |
| EP3074513A1 (en) | 2013-11-26 | 2016-10-05 | Novozymes A/S | Enzyme compositions and uses thereof |
| WO2015079064A2 (en) | 2013-11-29 | 2015-06-04 | Novozymes A/S | Peroxygenase variants |
| EP3077517B1 (en) | 2013-12-02 | 2018-10-17 | DSM IP Assets B.V. | Ice structuring protein |
| CN122012456A (zh) | 2013-12-11 | 2026-05-12 | 诺维信公司 | 角质酶变体以及对其进行编码的多核苷酸 |
| EP2886656A1 (en) | 2013-12-18 | 2015-06-24 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | New enzyme and method for preparing 4-hydroxyl benzyl alcohol and derivatives thereof |
| EP3453757B1 (en) | 2013-12-20 | 2020-06-17 | Novozymes A/S | Polypeptides having protease activity and polynucleotides encoding same |
| EP3097192B1 (en) | 2014-01-22 | 2018-07-25 | Novozymes A/S | Pullulanase variants and polynucleotides encoding same |
| CN106062270A (zh) | 2014-03-05 | 2016-10-26 | 诺维信公司 | 使用木葡聚糖内糖基转移酶改进非纤维素纺织材料的性质的组合物和方法 |
| CN106062271A (zh) | 2014-03-05 | 2016-10-26 | 诺维信公司 | 用于改进具有木葡聚糖内糖基转移酶的纤维素纺织材料的性质的组合物和方法 |
| EP3114276B1 (en) | 2014-03-05 | 2019-01-16 | Novozymes A/S | Compositions and methods for functionalizing and linking materials |
| EP3113609B1 (en) | 2014-03-05 | 2019-07-31 | Novozymes A/S | Methods for improving post-harvest properties of agricultural crops |
| EP3113611A1 (en) | 2014-03-05 | 2017-01-11 | Novozymes A/S | Formulations comprising polymeric xyloglucan as a carrier for agriculturally beneficial agents |
| US10155935B2 (en) | 2014-03-12 | 2018-12-18 | Novozymes A/S | Polypeptides with lipase activity and polynucleotides encoding same |
| WO2015150457A1 (en) | 2014-04-01 | 2015-10-08 | Novozymes A/S | Polypeptides having alpha amylase activity |
| WO2015157656A1 (en) | 2014-04-10 | 2015-10-15 | Novozymes A/S | Alpha-amylase variants and polynucleotides encoding same |
| CN106164236B (zh) | 2014-04-11 | 2021-02-02 | 诺维信公司 | 洗涤剂组合物 |
| US10030215B2 (en) | 2014-04-15 | 2018-07-24 | Novozymes A/S | Polypeptides with lipase activity and polynucleotides encoding same |
| WO2015177153A1 (en) | 2014-05-19 | 2015-11-26 | Dsm Ip Assets B.V. | Proline-specific endoprotease |
| MX375798B (es) | 2014-05-19 | 2025-03-07 | Dsm Ip Assets Bv | Endoproteasa específica para prolina. |
| WO2015177152A1 (en) | 2014-05-19 | 2015-11-26 | Dsm Ip Assets B.V. | Proline-specific endoprotease |
| EP3149178B1 (en) | 2014-05-27 | 2020-07-15 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
| CA2950273C (en) | 2014-05-30 | 2022-06-21 | Novozymes A/S | Variants of gh family 11 xylanase and polynucleotides encoding same |
| EP3152315B1 (en) | 2014-06-06 | 2018-08-15 | Novozymes A/S | Enzyme compositions and uses thereof |
| ES2712402T3 (es) | 2014-06-25 | 2019-05-13 | Novozymes As | Variantes de xilanasa y polinucleótidos que las codifican |
| US20170267980A1 (en) | 2014-08-20 | 2017-09-21 | Novozymes A/S | Xyloglucan Endotransglycosylase variants and Polynucleotides Encoding Same |
| EP3189137A1 (en) | 2014-09-05 | 2017-07-12 | Novozymes A/S | Carbohydrate binding module variants and polynucleotides encoding same |
| WO2016062875A2 (en) | 2014-10-23 | 2016-04-28 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| US10619145B2 (en) | 2014-11-04 | 2020-04-14 | Novozymes A/S | Polypeptides having serine protease activity and polynucleotides encoding same and their application in animal feed |
| WO2016079305A1 (en) | 2014-11-20 | 2016-05-26 | Novozymes A/S | Alicyclobacillus variants and polynucleotides encoding same |
| WO2016090059A1 (en) | 2014-12-02 | 2016-06-09 | Novozymes A/S | Laccase variants and polynucleotides encoding same |
| EP3227442B1 (en) | 2014-12-05 | 2022-02-16 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
| US20180000076A1 (en) | 2014-12-16 | 2018-01-04 | Novozymes A/S | Polypeptides Having N-Acetyl Glucosamine Oxidase Activity |
| MX383142B (es) | 2014-12-19 | 2025-03-13 | Novozymes As | Composiciones que comprenden polipéptidos que tienen actividad xilanasa y polipéptidos que tienen actividad arabinofuranosidasa. |
| WO2016100910A1 (en) | 2014-12-19 | 2016-06-23 | Novozymes A/S | Recombinant host cells for the production of 3-hydroxypropionic acid |
| FI3739045T3 (fi) | 2015-02-24 | 2024-11-13 | Novozymes As | Sellobiohydrolaasivariantteja ja niitä koodittavia polynukleotideja |
| EP3262161B1 (en) | 2015-02-27 | 2021-06-30 | Novozymes A/S | Mutant host cells for the production of 3-hydroxypropionic acid |
| US10385352B2 (en) | 2015-03-09 | 2019-08-20 | Novozymes A/S | Methods of introducing multiple expression constructs into a eukaryotic cell |
| US20180073017A1 (en) | 2015-04-07 | 2018-03-15 | Novozymes A/S | Methods for selecting enzymes having enhanced activity |
| US20180355404A1 (en) | 2015-04-07 | 2018-12-13 | Novozymes A/S | Methods for selecting enzymes having lipase activity |
| AR104205A1 (es) | 2015-04-09 | 2017-07-05 | Dsm Ip Assets Bv | Fosfolipasa c |
| CN107532154B (zh) | 2015-05-27 | 2022-09-27 | 国投生物科技投资有限公司 | 具有纤维二糖水解酶活性的多肽以及对其进行编码的多核苷酸 |
| AU2016273208B2 (en) | 2015-06-02 | 2021-01-21 | Dsm Ip Assets B.V. | Use of ice structuring protein AFP19 expressed in filamentous fungal strains for preparing food |
| EP3310908B1 (en) | 2015-06-16 | 2020-08-05 | Novozymes A/S | Polypeptides with lipase activity and polynucleotides encoding same |
| US10676727B2 (en) | 2015-06-18 | 2020-06-09 | Novozymes A/S | Polypeptides having trehalase activity and the use thereof in process of producing fermentation products |
| WO2016207373A1 (en) | 2015-06-26 | 2016-12-29 | Novozymes A/S | Polypeptides having peroxygenase activity |
| AU2016282355B2 (en) | 2015-06-26 | 2020-04-09 | Novozymes A/S | Method for producing a coffee extract |
| EP3313990A4 (en) | 2015-06-26 | 2019-01-23 | Novozymes A/S | BIO-finishing system |
| AU2016286612B2 (en) | 2015-07-02 | 2021-01-28 | Novozymes A/S | Animal feed compositions and uses thereof |
| CN114292829A (zh) | 2015-07-06 | 2022-04-08 | 诺维信公司 | 脂肪酶变体以及编码它们的多核苷酸 |
| WO2017019491A1 (en) | 2015-07-24 | 2017-02-02 | Novozymes Inc. | Polypeptides having beta-xylosidase activity and polynucleotides encoding same |
| CN108138153A (zh) | 2015-07-24 | 2018-06-08 | 诺维信股份有限公司 | 具有阿拉伯呋喃糖苷酶活性的多肽以及编码它们的多核苷酸 |
| WO2017017292A1 (es) | 2015-07-29 | 2017-02-02 | Abengoa Bioenergía Nuevas Tecnologías, S. A. | Expresión de enzimas beta-xilosidasas recombinantes |
| WO2017035270A1 (en) | 2015-08-24 | 2017-03-02 | Novozymes A/S | Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid |
| CA2991114A1 (en) | 2015-09-17 | 2017-03-23 | Novozymes A/S | Polypeptides having xanthan degrading activity and polynucleotides encoding same |
| US10479984B2 (en) | 2015-09-22 | 2019-11-19 | Novozymes A/S | Polypeptides having cellobiohydrolase activity and polynucleotides encoding same |
| WO2017050652A1 (en) | 2015-09-25 | 2017-03-30 | Dsm Ip Assets B.V. | Asparaginase |
| WO2017060475A2 (en) | 2015-10-07 | 2017-04-13 | Novozymes A/S | Polypeptides |
| CN108291212A (zh) | 2015-10-14 | 2018-07-17 | 诺维信公司 | 多肽变体 |
| US20180171318A1 (en) | 2015-10-14 | 2018-06-21 | Novozymes A/S | Polypeptides Having Protease Activity and Polynucleotides Encoding Same |
| EP3362574B1 (en) | 2015-10-14 | 2021-07-07 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| WO2017070219A1 (en) | 2015-10-20 | 2017-04-27 | Novozymes A/S | Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same |
| WO2017075426A1 (en) | 2015-10-30 | 2017-05-04 | Novozymes A/S | Polynucleotide constructs for in vitro and in vivo expression |
| US11001821B2 (en) | 2015-11-24 | 2021-05-11 | Novozymes A/S | Polypeptides having protease activity and polynucleotides encoding same |
| EP3384019B1 (en) | 2015-12-01 | 2020-06-24 | Novozymes A/S | Methods for producing lipases |
| BR112018011096A2 (pt) | 2015-12-02 | 2018-12-04 | Inst Nat De La Rech Agronomique Inra | novos peptídeos que têm atividade antimicrobiana e nova enzima capaz de converter resíduo de configuração l em aminoácido de configuração d em um peptídeo |
| JP7146637B2 (ja) | 2015-12-22 | 2022-10-04 | アルブミディクス リミティド | 改善されたタンパク質発現株 |
| WO2017112847A1 (en) | 2015-12-22 | 2017-06-29 | Albumedix A/S | Improved protein expression strains |
| CN108603185B (zh) | 2015-12-30 | 2022-05-17 | 诺维信公司 | 酶变体以及编码它们的多核苷酸 |
| US20210171927A1 (en) | 2016-01-29 | 2021-06-10 | Novozymes A/S | Beta-glucanase variants and polynucleotides encoding same |
| US11685911B2 (en) | 2016-02-16 | 2023-06-27 | Monaghan Mushroom S Group | Fungal polypeptides having lysozyme activity |
| US20190048413A1 (en) | 2016-02-23 | 2019-02-14 | Novozymes A/S | Improved next-generation sequencing |
| BR112018067371A2 (pt) | 2016-03-02 | 2019-01-15 | Novozymes As | variante de celobio-hidrolase, composição de enzimas, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo, célula hospedeira recombinante, planta, parte de planta ou célula de planta transgênica, métodos para produção e para obtenção de uma variante de celobio-hidrolase, planta trangênica, e, processos para degradação de um material celulósico, para produção de um produto de fermentação e para fermentação de um material celulósico |
| CN109072209A (zh) | 2016-03-24 | 2018-12-21 | 诺维信公司 | 纤维二糖水解酶变体和编码其的多核苷酸 |
| WO2017177153A1 (en) | 2016-04-07 | 2017-10-12 | Novozymes A/S | Methods for selecting enzymes having protease activity |
| DK3445776T3 (da) | 2016-04-19 | 2021-04-19 | Novozymes As | RLMA-inaktiveret filamentøs svampeværtscelle |
| US10626354B2 (en) | 2016-04-29 | 2020-04-21 | Novozymes A/S | Detergent compositions and uses thereof |
| US20240218340A1 (en) | 2016-05-03 | 2024-07-04 | Novozymes A/S | Enzyme Variants and Polynucleotides Encoding Same |
| JP6985295B2 (ja) | 2016-05-09 | 2021-12-22 | ノボザイムス アクティーゼルスカブ | 向上した性能を有する変異体ポリペプチドおよびその使用 |
| EP3246401A1 (en) | 2016-05-20 | 2017-11-22 | Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives | New fatty acid decarboxylase and its uses |
| AU2017270269A1 (en) | 2016-05-24 | 2018-11-15 | Novozymes A/S | Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity |
| CN109312321A (zh) | 2016-05-24 | 2019-02-05 | 诺维信公司 | 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物 |
| AU2017269498A1 (en) | 2016-05-24 | 2018-11-08 | Novozymes A/S | Polypeptides having alpha-galactosidase activity and polynucleotides encoding same |
| ES3014057T3 (en) | 2016-05-24 | 2025-04-16 | Novozymes As | Gastric stable polypeptides having alpha-galactosidase activity and polynucleotides encoding same |
| WO2017205535A1 (en) | 2016-05-27 | 2017-11-30 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| WO2017211803A1 (en) | 2016-06-07 | 2017-12-14 | Novozymes A/S | Co-expression of heterologous polypeptides to increase yield |
| US10829748B2 (en) | 2016-06-10 | 2020-11-10 | Dsm Ip Assets B.V. | Mutant lipase and use thereof |
| ES2807212T3 (es) | 2016-06-30 | 2021-02-22 | Fornia Biosolutions Inc | Nuevas fitasas y usos de las mismas |
| WO2018002261A1 (en) | 2016-07-01 | 2018-01-04 | Novozymes A/S | Detergent compositions |
| CN109715794A (zh) | 2016-07-05 | 2019-05-03 | 诺维信公司 | 果胶裂解酶变体以及编码它们的多核苷酸 |
| EP3481959A1 (en) | 2016-07-06 | 2019-05-15 | Novozymes A/S | Improving a microorganism by crispr-inhibition |
| MX2019000139A (es) | 2016-07-08 | 2019-06-10 | Novozymes As | Polipeptidos que tienen actividad xilanasa y polinucleotidos que los codifican. |
| WO2018007573A1 (en) | 2016-07-08 | 2018-01-11 | Novozymes A/S | Detergent compositions with galactanase |
| RU2752204C2 (ru) | 2016-07-08 | 2021-07-23 | Новозимс А/С | Варианты ксиланазы и кодирующие их полинуклеотиды |
| CN109415708A (zh) | 2016-07-13 | 2019-03-01 | 宝洁公司 | 食物芽孢杆菌脱氧核糖核酸酶变体及其用途 |
| CN109790525A (zh) | 2016-07-18 | 2019-05-21 | 诺维信公司 | 脂肪酶变体、编码其的多核苷酸及其用途 |
| WO2018017792A1 (en) | 2016-07-20 | 2018-01-25 | Novozymes A/S | Heat-stable metagenomic carbonic anhydrases and their use |
| CN109661465A (zh) | 2016-07-21 | 2019-04-19 | 诺维信公司 | 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸 |
| FI3487996T3 (fi) | 2016-07-21 | 2024-07-10 | Novozymes As | Seriiniproteaasivariantteja ja niitä koodittavia polynukleotideja |
| WO2018015444A1 (en) | 2016-07-22 | 2018-01-25 | Novozymes A/S | Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi |
| WO2018015443A1 (en) | 2016-07-22 | 2018-01-25 | Novozymes A/S | Improved filamentous fungal host |
| WO2018026868A1 (en) | 2016-08-01 | 2018-02-08 | Novozymes, Inc. | Polypeptides having endoglucanase activity and polynucleotides encoding same |
| US11512300B2 (en) | 2016-08-24 | 2022-11-29 | Novozymes A/S | Xanthan lyase variants and polynucleotides encoding same |
| EP3504330A1 (en) | 2016-08-24 | 2019-07-03 | Novozymes A/S | Gh9 endoglucanase variants and polynucleotides encoding same |
| WO2018037064A1 (en) | 2016-08-24 | 2018-03-01 | Henkel Ag & Co. Kgaa | Detergent compositions comprising xanthan lyase variants i |
| AU2017317564B2 (en) | 2016-08-24 | 2021-09-30 | Henkel Ag & Co. Kgaa | Detergent composition comprising GH9 endoglucanase variants I |
| CN109563522A (zh) | 2016-09-15 | 2019-04-02 | 诺维信公司 | 真菌宿主细胞中dna片段的基因组整合 |
| US20210284933A1 (en) | 2016-10-25 | 2021-09-16 | Novozymes A/S | Detergent compositions |
| EP3541954A1 (en) | 2016-11-21 | 2019-09-25 | Novozymes A/S | Yeast cell extract assisted construction of dna molecules |
| AU2017380488B2 (en) | 2016-12-21 | 2023-09-14 | Novozymes A/S | Polypeptides having lysozyme activity, polynucleotides encoding same and uses and compositions thereof |
| EP3577219B1 (en) | 2017-02-01 | 2023-08-23 | Novozymes A/S | Alpha-amylase variants |
| RU2019123965A (ru) | 2017-02-01 | 2021-02-01 | Дзе Проктер Энд Гэмбл Компани | Очищающие композиции, содержащие варианты амилазы |
| EP3596199A1 (en) | 2017-03-13 | 2020-01-22 | DSM IP Assets B.V. | Zinc binuclear cluster transcriptional regulator-deficient strain |
| WO2018167153A1 (en) | 2017-03-17 | 2018-09-20 | Novozymes A/S | Improved filamentous fungal host cell |
| WO2018172155A1 (en) | 2017-03-23 | 2018-09-27 | Novozymes A/S | Improved filamentous fungal host cells |
| EP3601549B1 (en) | 2017-03-31 | 2026-07-01 | Novozymes A/S | POLYPEPTIDES WITH DNASE ACTIVITY |
| CN110651041A (zh) | 2017-03-31 | 2020-01-03 | 诺维信公司 | 具有dna酶活性的多肽 |
| CN110651040A (zh) | 2017-03-31 | 2020-01-03 | 诺维信公司 | 具有dna酶活性的多肽 |
| US11149233B2 (en) | 2017-03-31 | 2021-10-19 | Novozymes A/S | Polypeptides having RNase activity |
| CN110651029B (zh) | 2017-04-04 | 2022-02-15 | 诺维信公司 | 糖基水解酶 |
| EP3607039A1 (en) | 2017-04-04 | 2020-02-12 | Novozymes A/S | Polypeptides |
| WO2018185152A1 (en) | 2017-04-04 | 2018-10-11 | Novozymes A/S | Polypeptide compositions and uses thereof |
| BR112019021223A2 (pt) | 2017-04-11 | 2020-04-28 | Novozymes A/S | variante de glucoamilase, métodos para aumentar a atividade de hidrólise de amido em bruto de uma glucoamilase e para produzir uma variante de glucoamilase, composição, uso de uma variante de glucoamilase, processos para produzir um produto de fermentação e para produzir um produto de xarope, polinucleotídeo codificando a variante de glucoamilase, construto de ácido nucleico, vetor de expressão, e, célula hospedeira. |
| WO2018202846A1 (en) | 2017-05-05 | 2018-11-08 | Novozymes A/S | Compositions comprising lipase and sulfite |
| WO2018206535A1 (en) | 2017-05-08 | 2018-11-15 | Novozymes A/S | Carbohydrate-binding domain and polynucleotides encoding the same |
| EP3401385A1 (en) | 2017-05-08 | 2018-11-14 | Henkel AG & Co. KGaA | Detergent composition comprising polypeptide comprising carbohydrate-binding domain |
| WO2018224035A1 (en) | 2017-06-09 | 2018-12-13 | Novozymes A/S | Polypeptide, use and method for hydrolysing protein |
| EP4026908A1 (en) | 2017-06-20 | 2022-07-13 | Albumedix Ltd | Improved protein expression strains |
| EP3642339B1 (en) | 2017-06-22 | 2025-09-10 | Novozymes A/S | Xylanase variants and polynucleotides encoding same |
| DK3645555T3 (da) | 2017-06-28 | 2022-03-07 | Novozymes As | Polypeptider med trehalaseaktivitet og polynukleotider, der koder for disse |
| KR102683528B1 (ko) | 2017-07-24 | 2024-07-10 | 노보자임스 에이/에스 | 습식 제분에서의 gh5 및 gh30 |
| US10081800B1 (en) | 2017-08-03 | 2018-09-25 | Fornia Biosolutions, Inc. | Lactonase enzymes and methods of using same |
| CA3070281A1 (en) | 2017-08-08 | 2019-02-14 | Novozymes A/S | Polypeptides having trehalase activity and the use thereof in process of producing fermentation products |
| EP3673056A1 (en) | 2017-08-24 | 2020-07-01 | Henkel AG & Co. KGaA | Detergent compositions comprising gh9 endoglucanase variants ii |
| CN111344404A (zh) | 2017-08-24 | 2020-06-26 | 诺维信公司 | 黄原胶裂解酶变体以及编码其的多核苷酸 |
| US20210130744A1 (en) | 2017-08-24 | 2021-05-06 | Henkel Ag & Co. Kgaa | Detergent composition comprising xanthan lyase variants ii |
| WO2019038058A1 (en) | 2017-08-24 | 2019-02-28 | Novozymes A/S | GH9 ENDOGLUCANASE VARIANTS AND POLYNUCLEOTIDES ENCODING SUCH VARIANTS |
| CN111050566A (zh) | 2017-09-01 | 2020-04-21 | 诺维信公司 | 包含具有蛋白酶活性的多肽的动物饲料添加剂及其用途 |
| WO2019046703A1 (en) | 2017-09-01 | 2019-03-07 | Novozymes A/S | METHODS OF ENHANCING GENOME EDITION IN FUNGI |
| US20200196633A1 (en) | 2017-09-01 | 2020-06-25 | Novozymes A/S | Animal Feed Additives Comprising Polypeptide Having Protease Activity and Uses Thereof |
| PL3688149T3 (pl) | 2017-09-26 | 2025-03-24 | Bunge Global Innovation, Llc. | Enzymatyczne usuwanie substratów chlorofilowych z olejów na bazie triacyloglicerolu |
| CN118910005A (zh) | 2017-09-27 | 2024-11-08 | 诺维信公司 | 脂肪酶变体和包含此类脂肪酶变体的微囊组合物 |
| EP3673039B1 (en) * | 2017-09-29 | 2025-03-19 | International N&H Denmark ApS | Production of brewer's wort having increased fermentable sugars |
| CN111373036A (zh) | 2017-10-02 | 2020-07-03 | 诺维信公司 | 具有甘露聚糖酶活性的多肽和编码它们的多核苷酸 |
| US11746310B2 (en) | 2017-10-02 | 2023-09-05 | Novozymes A/S | Polypeptides having mannanase activity and polynucleotides encoding same |
| WO2019081724A1 (en) | 2017-10-27 | 2019-05-02 | Novozymes A/S | VARIANTS OF DNASE |
| PL3476936T3 (pl) | 2017-10-27 | 2022-04-11 | The Procter & Gamble Company | Kompozycje detergentu zawierające odmiany polipeptydowe |
| DE102017125560A1 (de) | 2017-11-01 | 2019-05-02 | Henkel Ag & Co. Kgaa | Reinigungszusammensetzungen, die dispersine iii enthalten |
| DE102017125559A1 (de) | 2017-11-01 | 2019-05-02 | Henkel Ag & Co. Kgaa | Reinigungszusammensetzungen, die dispersine ii enthalten |
| DE102017125558A1 (de) | 2017-11-01 | 2019-05-02 | Henkel Ag & Co. Kgaa | Reinigungszusammensetzungen, die dispersine i enthalten |
| EP3707252A1 (en) | 2017-11-10 | 2020-09-16 | Novozymes A/S | Temperature-sensitive cas9 protein |
| WO2019096903A1 (en) | 2017-11-20 | 2019-05-23 | Novozymes A/S | New galactanases (ec 3.2.1.89) for use in soy processing |
| EP3485734A1 (en) | 2017-11-21 | 2019-05-22 | Technische Universität München | Method for preparing food products comprising rye |
| EP3488854A1 (en) | 2017-11-22 | 2019-05-29 | Technische Universität München | Method for preparing xyloglucan-oligosaccharides |
| US11725197B2 (en) | 2017-12-04 | 2023-08-15 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
| EP3502242A1 (en) | 2017-12-20 | 2019-06-26 | Technische Universität München | New xylanase with improved thermostability and increased enzyme activity on arabinoxylan |
| US20210017544A1 (en) | 2017-12-22 | 2021-01-21 | Novozymes A/S | Counter-Selection by Inhibition of Conditionally Essential Genes |
| KR101992345B1 (ko) * | 2017-12-29 | 2019-09-27 | (주)메디톡스 | 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도 |
| US20210123033A1 (en) | 2018-02-08 | 2021-04-29 | Novozymes A/S | Lipases, Lipase Variants and Compositions Thereof |
| US20210071155A1 (en) | 2018-02-08 | 2021-03-11 | Novozymes A/S | Lipase Variants and Compositions Thereof |
| CN112004931A (zh) | 2018-03-26 | 2020-11-27 | 诺维信公司 | 真菌伴侣蛋白 |
| CN112105729B (zh) | 2018-04-09 | 2024-05-14 | 诺维信公司 | 具有α-淀粉酶活性的多肽以及编码它们的多核苷酸 |
| US11566239B2 (en) | 2018-04-19 | 2023-01-31 | Novozymes A/S | Stabilized cellulase variants |
| CN112272701B (zh) | 2018-04-19 | 2024-05-14 | 诺维信公司 | 稳定化的纤维素酶变体 |
| US20230080079A1 (en) | 2018-05-18 | 2023-03-16 | Dsm Ip Assets B.V. | Mutant lipase and use thereof |
| WO2019219904A2 (en) | 2018-05-18 | 2019-11-21 | Dsm Ip Assets B.V. | Mutant lipase and use thereof |
| WO2020002575A1 (en) | 2018-06-28 | 2020-01-02 | Novozymes A/S | Polypeptides having pectin lyase activity and polynucleotides encoding same |
| WO2020025357A1 (en) | 2018-08-02 | 2020-02-06 | Novozymes A/S | Preparation of combinatorial libraries of dna constructs using introns |
| US11473076B2 (en) | 2018-08-31 | 2022-10-18 | Novozymes A/S | Animal feed additives and compositions comprising an S8 serine protease |
| CN113056476A (zh) | 2018-10-03 | 2021-06-29 | 诺维信公司 | 具有α-甘露聚糖降解活性的多肽以及编码它们的多核苷酸 |
| EP3864136A1 (en) | 2018-10-09 | 2021-08-18 | Novozymes A/S | Modified filamentous fungal host cell |
| EP3874051A1 (en) | 2018-10-31 | 2021-09-08 | Novozymes A/S | Genome editing by guided endonuclease and single-stranded oligonucleotide |
| WO2020112911A1 (en) | 2018-11-28 | 2020-06-04 | Novozymes A/S | Improved filamentous fungal host cells |
| US20220025423A1 (en) | 2018-11-28 | 2022-01-27 | Novozymes A/S | Modified Filamentous Fungal Host Cells |
| WO2020123463A1 (en) | 2018-12-12 | 2020-06-18 | Novozymes A/S | Polypeptides having xylanase activity and polynucleotides encoding same |
| CN109652417B (zh) * | 2018-12-17 | 2021-07-27 | 江南大学 | 一种构建高效枯草芽孢杆菌启动子的方法 |
| EP3898962A2 (en) | 2018-12-21 | 2021-10-27 | Novozymes A/S | Polypeptides having peptidoglycan degrading activity and polynucleotides encoding same |
| WO2020127198A1 (en) | 2018-12-21 | 2020-06-25 | Novozymes A/S | Tandem protein expression |
| CA3126184A1 (en) | 2019-01-11 | 2020-07-16 | River Stone Biotech Aps | Recombinant host cells with improved production of l-dopa, dopamine, (s)-norcoclaurine or derivatives thereof |
| WO2020161354A1 (en) | 2019-02-08 | 2020-08-13 | Pili | Recombinant host cells to produce anthraquinone derivatives |
| WO2020173817A1 (en) | 2019-02-28 | 2020-09-03 | Novozymes A/S | Calcite binding proteins |
| EP3737751B1 (en) | 2019-03-21 | 2026-08-12 | Fornia BioSolutions, Inc. | Additional phytase variants and methods |
| EP3946720A1 (en) | 2019-03-27 | 2022-02-09 | Bunge Global Innovation, LLC. | Silica adsorbent treatment for removal of chlorophyll derivatives from triacylglycerol-based oils |
| CN113785039B (zh) | 2019-04-03 | 2024-06-18 | 诺维信公司 | 具有β-葡聚糖酶活性的多肽、编码其的多核苷酸及其在清洁和洗涤剂组合物中的用途 |
| US12247237B2 (en) | 2019-04-10 | 2025-03-11 | Novozymes A/S | Polypeptide variants |
| MX2021012289A (es) | 2019-04-12 | 2021-11-12 | Novozymes As | Variantes de glucosido hidrolasa estabilizadas. |
| WO2020229191A1 (en) | 2019-05-15 | 2020-11-19 | Novozymes A/S | Temperature-sensitive rna-guided endonuclease |
| CN114207108A (zh) | 2019-05-27 | 2022-03-18 | 奥克塔林生物制剂公司 | 产生糖基化大麻素的基因修饰的宿主细胞 |
| US20220251528A1 (en) | 2019-06-24 | 2022-08-11 | Novozymes A/S | Alpha-Amylase Variants |
| EP3986996A1 (en) | 2019-06-24 | 2022-04-27 | The Procter & Gamble Company | Cleaning compositions comprising amylase variants |
| EP3990629A1 (en) | 2019-06-25 | 2022-05-04 | Novozymes A/S | Counter-selection by inhibition of conditionally essential genes |
| EP3994255A1 (en) | 2019-07-02 | 2022-05-11 | Novozymes A/S | Lipase variants and compositions thereof |
| EP4004211A1 (en) | 2019-07-25 | 2022-06-01 | Novozymes A/S | Filamentous fungal expression system |
| US20220251581A1 (en) | 2019-07-26 | 2022-08-11 | Novozymes A/S | Modified filamentous fungal host cell |
| WO2021048172A2 (en) | 2019-09-09 | 2021-03-18 | River Stone Biotech Aps | Delivery vehicle for in situ delivering of pharmaceutical agents |
| EP4031661A1 (en) | 2019-09-16 | 2022-07-27 | Novozymes A/S | Polypeptides having beta-glucanase activity and polynucleotides encoding same |
| EP4038170A1 (en) | 2019-10-03 | 2022-08-10 | Novozymes A/S | Polypeptides comprising at least two carbohydrate binding domains |
| CN114761551B (zh) | 2019-12-19 | 2025-09-12 | 诺维信公司 | 木聚糖酶变体和编码其的多核苷酸 |
| EP4077656A2 (en) | 2019-12-20 | 2022-10-26 | Novozymes A/S | Polypeptides having proteolytic activity and use thereof |
| WO2021148278A1 (en) | 2020-01-24 | 2021-07-29 | Novozymes A/S | Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide |
| EP4097226A1 (en) | 2020-01-31 | 2022-12-07 | Novozymes A/S | Mannanase variants and polynucleotides encoding same |
| WO2021152123A1 (en) | 2020-01-31 | 2021-08-05 | Novozymes A/S | Mannanase variants and polynucleotides encoding same |
| WO2021163030A2 (en) | 2020-02-10 | 2021-08-19 | Novozymes A/S | Polypeptides having alpha-amylase activity and polynucleotides encoding same |
| MX2022009515A (es) | 2020-02-10 | 2022-09-02 | Novozymes As | Variantes de alfa-amilasa y polinucleotidos que las codifican. |
| WO2021163015A1 (en) | 2020-02-10 | 2021-08-19 | Novozymes A/S | Process for producing ethanol from raw starch using alpha-amylase variants |
| EP4110909A1 (en) | 2020-02-26 | 2023-01-04 | Novozymes A/S | Polypeptide variants |
| CN115427560A (zh) | 2020-03-12 | 2022-12-02 | 诺维信公司 | 使用无催化活性rna指导的内切核酸酶的crispr-aid |
| EP3892708A1 (en) | 2020-04-06 | 2021-10-13 | Henkel AG & Co. KGaA | Cleaning compositions comprising dispersin variants |
| EP4133066A1 (en) | 2020-04-08 | 2023-02-15 | Novozymes A/S | Carbohydrate binding module variants |
| CN115516071A (zh) | 2020-04-21 | 2022-12-23 | 诺维信公司 | 包含具有果聚糖降解活性的多肽的清洁组合物 |
| JP7885201B2 (ja) | 2020-08-25 | 2026-07-06 | ノボザイムス アクティーゼルスカブ | ファミリー44キシログルカナーゼの変異体 |
| EP4204548A1 (en) | 2020-08-28 | 2023-07-05 | Novozymes A/S | Polyester degrading protease variants |
| US20230407273A1 (en) | 2020-10-13 | 2023-12-21 | Novozymes A/S | Glycosyltransferase variants for improved protein production |
| WO2022090361A2 (en) | 2020-10-29 | 2022-05-05 | Novozymes A/S | Lipase variants and compositions comprising such lipase variants |
| US20240271175A1 (en) | 2020-11-02 | 2024-08-15 | Novozymes A/S | Leader peptides and polynucleotides encoding the same |
| AU2021370998A1 (en) | 2020-11-02 | 2023-05-25 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| EP4026900A3 (en) | 2020-12-17 | 2022-10-05 | Fornia BioSolutions, Inc. | Xylanase variants and methods |
| WO2022175440A1 (en) | 2021-02-18 | 2022-08-25 | Novozymes A/S | Inactive heme polypeptides |
| EP4305146A1 (en) | 2021-03-12 | 2024-01-17 | Novozymes A/S | Polypeptide variants |
| MX2023005793A (es) | 2021-03-15 | 2023-05-29 | Procter & Gamble | Composiciones de limpieza que contienen variantes de polipeptido. |
| EP4060036A1 (en) | 2021-03-15 | 2022-09-21 | Novozymes A/S | Polypeptide variants |
| US20240060061A1 (en) | 2021-03-15 | 2024-02-22 | Novozymes A/S | Dnase variants |
| AU2022270929A1 (en) | 2021-05-07 | 2023-10-19 | River Stone Biotech Aps | Glycosylated opioids |
| CN117355608A (zh) | 2021-05-27 | 2024-01-05 | 诺维信公司 | 转录调节物和编码其的多核苷酸 |
| EP4359518A1 (en) | 2021-06-23 | 2024-05-01 | Novozymes A/S | Alpha-amylase polypeptides |
| WO2023006699A1 (en) | 2021-07-30 | 2023-02-02 | Københavns Universitet | Cells and method for producing isoprenoid molecules with canonical and non-canonical structures |
| US20260168000A1 (en) | 2022-11-08 | 2026-06-18 | River Stone Biotech Aps | Genetically modified benzylisoquinoline alkaloid-producing host cells with modified efflux transporter gene expression |
| CN116675748A (zh) * | 2023-04-28 | 2023-09-01 | 河南农业大学 | 一种假禾谷镰孢分泌的植物免疫激活蛋白FpCDP1及其应用 |
| WO2026017657A1 (fr) | 2024-07-15 | 2026-01-22 | Pili | Production d'acide p-aminobenzoïque par un microorganisme recombinant |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| EP0305216B1 (en) | 1987-08-28 | 1995-08-02 | Novo Nordisk A/S | Recombinant Humicola lipase and process for the production of recombinant humicola lipases |
| ES2121786T3 (es) | 1990-09-13 | 1998-12-16 | Novo Nordisk As | Variantes de lipasa. |
| US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| GB9316883D0 (en) * | 1993-08-13 | 1993-09-29 | Univ Leeds | Production of heterologous peptices |
| CA2191718A1 (en) | 1994-06-03 | 1995-12-14 | Randy M. Berka | Phosphonyldipeptides useful in the treatment of cardiovascular diseases |
| ATE294871T1 (de) * | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
| AU1750697A (en) | 1996-01-19 | 1997-08-11 | Novo Nordisk Biotech, Inc. | Morphological mutants of filamentous fungi |
| CN1190673A (zh) * | 1996-04-29 | 1998-08-19 | 中国科学院微生物研究所 | 丝状真菌中独立复制的表达载体及表达系统 |
| JP4436934B2 (ja) | 1996-09-13 | 2010-03-24 | ノボザイムス,インコーポレイティド | 変更された量のポリペプチドを生成するdna挿入突然変異を有する細胞 |
| WO1998028408A1 (en) | 1996-12-20 | 1998-07-02 | Novo Nordisk A/S | Peniophora phytase |
-
2000
- 2000-03-22 EP EP00919596A patent/EP1194572A2/en not_active Withdrawn
- 2000-03-22 CN CNB2004100314931A patent/CN100532561C/zh not_active Expired - Fee Related
- 2000-03-22 DK DK10180302.1T patent/DK2278016T3/da active
- 2000-03-22 CN CNB2004100314912A patent/CN100510096C/zh not_active Expired - Fee Related
- 2000-03-22 WO PCT/US2000/007815 patent/WO2000056900A2/en not_active Ceased
- 2000-03-22 CN CNB008053324A patent/CN100482801C/zh not_active Expired - Fee Related
- 2000-03-22 JP JP2000606759A patent/JP4620253B2/ja not_active Expired - Fee Related
- 2000-03-22 CN CNA2006100999266A patent/CN1940067A/zh active Pending
- 2000-03-22 EP EP10180302A patent/EP2278016B1/en not_active Expired - Lifetime
- 2000-03-22 CN CN 200410031492 patent/CN1526820B/zh not_active Expired - Fee Related
- 2000-03-22 AU AU40257/00A patent/AU4025700A/en not_active Abandoned
-
2010
- 2010-05-12 JP JP2010109995A patent/JP5264825B2/ja not_active Expired - Fee Related
-
2013
- 2013-02-06 JP JP2013021124A patent/JP2013121360A/ja active Pending
- 2013-02-06 JP JP2013021169A patent/JP2013121361A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN1536089A (zh) | 2004-10-13 |
| EP2278016B1 (en) | 2012-09-26 |
| CN1526820B (zh) | 2010-05-26 |
| CN1526821A (zh) | 2004-09-08 |
| CN1526820A (zh) | 2004-09-08 |
| JP2010227108A (ja) | 2010-10-14 |
| WO2000056900A3 (en) | 2002-01-31 |
| DK2278016T3 (da) | 2012-11-26 |
| JP2002539793A (ja) | 2002-11-26 |
| CN1367838A (zh) | 2002-09-04 |
| AU4025700A (en) | 2000-10-09 |
| JP2013121361A (ja) | 2013-06-20 |
| JP5264825B2 (ja) | 2013-08-14 |
| CN100482801C (zh) | 2009-04-29 |
| CN1940067A (zh) | 2007-04-04 |
| EP2278016A1 (en) | 2011-01-26 |
| JP2013121360A (ja) | 2013-06-20 |
| CN100510096C (zh) | 2009-07-08 |
| CN100532561C (zh) | 2009-08-26 |
| WO2000056900A2 (en) | 2000-09-28 |
| EP1194572A2 (en) | 2002-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5264825B2 (ja) | 菌類細胞中で遺伝子を発現させるためのプロモーター | |
| CN1425068B (zh) | 在制备多肽的方法中有效的真菌转录激活因子 | |
| US7919275B2 (en) | Oxaloacetate hydrolase deficient fungal host cells | |
| JP4563585B2 (ja) | ポリペプチドの生成方法において有用な菌類転写活性化因子 | |
| JP2011101651A (ja) | オキサロ酢酸ヒドロラーゼ欠陥真菌宿主細胞 | |
| JP2009543560A (ja) | 真菌細胞中の遺伝子発現を上昇させる方法 | |
| EP1078081B1 (en) | Methods for producing heterologous polypeptides in trichothecene-deficient filamentous fungal mutant cells | |
| US8426164B2 (en) | Fungal transcriptional activator useful in methods for producing polypeptides | |
| EP1616580B1 (en) | Alpha-amylase transcription factor | |
| JP4927281B2 (ja) | 共通翻訳開始配列を用いるポリペプチドの産生方法 | |
| EP1078080A1 (en) | Methods for producing polypeptides in filamentous fungal mutant cells | |
| US6692940B2 (en) | Promoters for expressing genes in a fungal cell | |
| CN1969041B (zh) | 用于生产多肽的信号肽 | |
| EP1032683B1 (en) | Polypeptides having 5-aminolevulinic acid synthase activity and nucleic acids encoding same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070314 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070314 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20091117 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100216 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100223 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100512 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100810 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100830 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100928 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20101028 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20131105 Year of fee payment: 3 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |