DK2769985T3 - Polypeptider fra Aspergillus aculeatus med C4-dicarboxylsyre-transportøraktivitet samt polynukleotider, som koder for samme - Google Patents
Polypeptider fra Aspergillus aculeatus med C4-dicarboxylsyre-transportøraktivitet samt polynukleotider, som koder for sammeInfo
- Publication number
- DK2769985T3 DK2769985T3 DK14162246.4T DK14162246T DK2769985T3 DK 2769985 T3 DK2769985 T3 DK 2769985T3 DK 14162246 T DK14162246 T DK 14162246T DK 2769985 T3 DK2769985 T3 DK 2769985T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptides
- same
- dicarboxylic acid
- polynucleotides encoding
- acid transporter
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
- C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
- C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
- C12Y604/01001—Pyruvate carboxylase (6.4.1.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35686810P | 2010-06-21 | 2010-06-21 | |
| EP11728506.4A EP2582716A1 (en) | 2010-06-21 | 2011-06-21 | Aspergillus aculeatus derived polypeptides having c4-dicarboxylic acid transporter activity and polynucleotides encoding same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2769985T3 true DK2769985T3 (da) | 2018-01-29 |
Family
ID=44314352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14162246.4T DK2769985T3 (da) | 2010-06-21 | 2011-06-21 | Polypeptider fra Aspergillus aculeatus med C4-dicarboxylsyre-transportøraktivitet samt polynukleotider, som koder for samme |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8158395B2 (da) |
| EP (2) | EP2582716A1 (da) |
| JP (1) | JP5912111B2 (da) |
| KR (1) | KR20130113937A (da) |
| CN (1) | CN103080126B (da) |
| AU (1) | AU2011271094B2 (da) |
| BR (1) | BR112012029891A2 (da) |
| CA (1) | CA2803343C (da) |
| DK (1) | DK2769985T3 (da) |
| MX (1) | MX2012014627A (da) |
| WO (1) | WO2011163269A1 (da) |
| ZA (1) | ZA201209441B (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011028643A1 (en) * | 2009-09-01 | 2011-03-10 | Novozymes, Inc. | Methods for improving malic acid production in filamentous fungi |
| CN106148209B (zh) * | 2015-03-23 | 2020-11-20 | 中国科学院天津工业生物技术研究所 | 新的二元有机酸生产菌株及其制备和应用 |
| CN106148208B (zh) * | 2015-03-23 | 2020-12-18 | 中国科学院天津工业生物技术研究所 | 新的二元有机酸生产菌株及其制备和应用 |
| JP6944748B2 (ja) * | 2016-06-29 | 2021-10-06 | 花王株式会社 | Ｃ４ジカルボン酸の製造方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1047002A (en) | 1911-04-03 | 1912-12-10 | James S Diehl | Scissors. |
| US3063910A (en) | 1960-02-03 | 1962-11-13 | Kyowa Hakko Kogyo Kk | Method of producing l-malic acid by fermentation |
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| US5536661A (en) | 1987-03-10 | 1996-07-16 | Novo Nordisk A/S | Process for the production of protein products in aspergillus |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IL97645A (en) | 1990-03-23 | 1997-03-18 | Gist Brocades Nv | Production of enzymes in seeds and their use |
| US6395966B1 (en) | 1990-08-09 | 2002-05-28 | Dekalb Genetics Corp. | Fertile transgenic maize plants containing a gene encoding the pat protein |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| CN1192108C (zh) | 1994-06-03 | 2005-03-09 | 诺沃奇梅兹生物技术有限公司 | 纯化的毁丝霉属漆酶及编码该酶的核酸 |
| ATE294871T1 (de) | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
| US5766439A (en) | 1996-10-10 | 1998-06-16 | A. E. Staley Manufacturing Co. | Production and recovery of organic acids |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| US7504490B1 (en) | 1998-10-16 | 2009-03-17 | Oscient Pharmaceuticals Corporation | Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics |
| AU6188599A (en) | 1998-10-26 | 2000-05-15 | Novozymes A/S | Constructing and screening a dna library of interest in filamentous fungal cells |
| US6511824B1 (en) | 1999-03-17 | 2003-01-28 | Exelixis, Inc. | Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use |
| EP2278016B1 (en) | 1999-03-22 | 2012-09-26 | Novozymes Inc. | Promoter sequences derived from Fusarium Venenatum and uses thereof |
| US6531644B1 (en) | 2000-01-14 | 2003-03-11 | Exelixis, Inc. | Methods for identifying anti-cancer drug targets |
| CA2425671A1 (en) | 2000-10-12 | 2002-04-18 | Exelixis, Inc. | Human ect2 and methods of use |
| US7151204B2 (en) | 2001-01-09 | 2006-12-19 | Monsanto Technology Llc | Maize chloroplast aldolase promoter compositions and methods for use thereof |
| CN1938257A (zh) | 2004-01-29 | 2007-03-28 | 齐凯姆公司 | 有机酸的回收 |
| US20080090273A1 (en) | 2005-11-21 | 2008-04-17 | Aaron Adriaan Winkler | Malic Acid Production in Recombinant Yeast |
| EP2155885A4 (en) * | 2007-05-18 | 2010-12-01 | Microbia Prec Engineering Inc | ACIDIC ACID PRODUCTION IN RECOMBINANT YEAST |
| US20110039327A1 (en) * | 2007-05-18 | 2011-02-17 | Aaron Adriaan Winkler | Organic acid production by fungal cells |
| ES2522622T3 (es) | 2007-11-20 | 2014-11-17 | Dsm Ip Assets B.V. | Producción de ácido succínico en una célula eucariota |
| US8129154B2 (en) | 2008-06-17 | 2012-03-06 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
| CA2730595C (en) | 2008-07-08 | 2014-12-16 | Dsm Ip Assets B.V. | Low ph dicarboxylic acid production |
| WO2010111344A2 (en) | 2009-03-24 | 2010-09-30 | Microbia, Inc. | Methods and microorganisms for production of c4-dicarboxylic acids |
| JP2012223091A (ja) | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| WO2011028643A1 (en) * | 2009-09-01 | 2011-03-10 | Novozymes, Inc. | Methods for improving malic acid production in filamentous fungi |
| CA2780179A1 (en) | 2009-11-06 | 2011-05-12 | Novozymes, Inc. | Compositions for saccharification of cellulosic material |
| WO2011066304A2 (en) | 2009-11-25 | 2011-06-03 | Codexis, Inc. | Engineered beta-class carbonic anhydrase polypeptides and uses thereof |
-
2011
- 2011-06-21 CN CN201180040520.XA patent/CN103080126B/zh active Active
- 2011-06-21 MX MX2012014627A patent/MX2012014627A/es active IP Right Grant
- 2011-06-21 JP JP2013516699A patent/JP5912111B2/ja active Active
- 2011-06-21 DK DK14162246.4T patent/DK2769985T3/da active
- 2011-06-21 BR BR112012029891A patent/BR112012029891A2/pt not_active Application Discontinuation
- 2011-06-21 CA CA2803343A patent/CA2803343C/en not_active Expired - Fee Related
- 2011-06-21 KR KR1020127032159A patent/KR20130113937A/ko not_active Application Discontinuation
- 2011-06-21 WO PCT/US2011/041300 patent/WO2011163269A1/en active Application Filing
- 2011-06-21 EP EP11728506.4A patent/EP2582716A1/en not_active Withdrawn
- 2011-06-21 US US13/165,696 patent/US8158395B2/en not_active Expired - Fee Related
- 2011-06-21 EP EP14162246.4A patent/EP2769985B1/en not_active Not-in-force
- 2011-06-21 AU AU2011271094A patent/AU2011271094B2/en not_active Ceased
-
2012
- 2012-02-24 US US13/404,258 patent/US8518676B2/en not_active Expired - Fee Related
- 2012-12-12 ZA ZA2012/09441A patent/ZA201209441B/en unknown
-
2013
- 2013-07-23 US US13/948,945 patent/US9303275B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012029891A2 (pt) | 2021-07-06 |
| WO2011163269A1 (en) | 2011-12-29 |
| US8158395B2 (en) | 2012-04-17 |
| US20120149079A1 (en) | 2012-06-14 |
| ZA201209441B (en) | 2013-08-28 |
| US9303275B2 (en) | 2016-04-05 |
| AU2011271094A1 (en) | 2012-11-29 |
| CN103080126A (zh) | 2013-05-01 |
| US8518676B2 (en) | 2013-08-27 |
| KR20130113937A (ko) | 2013-10-16 |
| EP2769985B1 (en) | 2017-12-06 |
| CA2803343C (en) | 2018-08-07 |
| JP2013534825A (ja) | 2013-09-09 |
| AU2011271094B2 (en) | 2015-01-22 |
| US20110312047A1 (en) | 2011-12-22 |
| JP5912111B2 (ja) | 2016-04-27 |
| CA2803343A1 (en) | 2011-12-29 |
| MX2012014627A (es) | 2013-02-21 |
| CN103080126B (zh) | 2016-05-11 |
| EP2769985A1 (en) | 2014-08-27 |
| EP2582716A1 (en) | 2013-04-24 |
| US20130302865A1 (en) | 2013-11-14 |
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