BRPI0917573A2 - - Google Patents

Info

Publication number
BRPI0917573A2
BRPI0917573A2 BRPI0917573A BRPI0917573A2 BR PI0917573 A2 BRPI0917573 A2 BR PI0917573A2 BR PI0917573 A BRPI0917573 A BR PI0917573A BR PI0917573 A2 BRPI0917573 A2 BR PI0917573A2
Authority
BR
Brazil
Application number
Other languages
Portuguese (pt)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41608613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0917573(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of BRPI0917573A2 publication Critical patent/BRPI0917573A2/pt
Publication of BRPI0917573B1 publication Critical patent/BRPI0917573B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08Radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/001Preparations for care of the lips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0917573-3A 2008-08-04 2009-03-02 Método de preparação de uma composição de enchimento de tecido mole; e método de preparação de uma composição de enchimento com base em HA coesiva BRPI0917573B1 (pt)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US8595608P 2008-08-04 2008-08-04
US61/085,956 2008-08-04
US8793408P 2008-08-11 2008-08-11
US61/087,934 2008-08-11
US9627808P 2008-09-11 2008-09-11
US61/096,278 2008-09-11
US12/393,884 2009-02-26
US12/393,768 2009-02-26
US12/393,768 US8450475B2 (en) 2008-08-04 2009-02-26 Hyaluronic acid-based gels including lidocaine
US12/393,884 US8357795B2 (en) 2008-08-04 2009-02-26 Hyaluronic acid-based gels including lidocaine
PCT/IB2009/005048 WO2010015901A1 (en) 2008-08-04 2009-03-02 Hyaluronic acid-based gels including anesthetic agents

Publications (2)

Publication Number Publication Date
BRPI0917573A2 true BRPI0917573A2 (https=) 2017-07-11
BRPI0917573B1 BRPI0917573B1 (pt) 2018-03-13

Family

ID=41608613

Family Applications (3)

Application Number Title Priority Date Filing Date
BRPI0917588-1A BRPI0917588B1 (pt) 2008-08-04 2009-03-02 Método de preparação de uma composição de enchimento de tecido mole
BRPI0917573-3A BRPI0917573B1 (pt) 2008-08-04 2009-03-02 Método de preparação de uma composição de enchimento de tecido mole; e método de preparação de uma composição de enchimento com base em HA coesiva
BRPI0917588D BRPI0917588A2 (pt) 2008-08-04 2009-03-02 Método de preparação de uma composição de enchimento de tecido mole

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0917588-1A BRPI0917588B1 (pt) 2008-08-04 2009-03-02 Método de preparação de uma composição de enchimento de tecido mole

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0917588D BRPI0917588A2 (pt) 2008-08-04 2009-03-02 Método de preparação de uma composição de enchimento de tecido mole

Country Status (19)

Country Link
US (22) US8357795B2 (https=)
EP (6) EP3662889A1 (https=)
JP (5) JP5670899B2 (https=)
KR (2) KR101747441B1 (https=)
CN (3) CN102170855B (https=)
AU (2) AU2009278884B2 (https=)
BR (3) BRPI0917588B1 (https=)
CA (6) CA3209175A1 (https=)
CY (2) CY1118281T1 (https=)
DK (3) DK2323617T3 (https=)
ES (3) ES2622708T3 (https=)
HU (3) HUE031483T2 (https=)
MX (3) MX342613B (https=)
PL (3) PL2323617T3 (https=)
PT (2) PT2326302T (https=)
RU (2) RU2496473C2 (https=)
SG (2) SG10202104803SA (https=)
SI (2) SI2323617T1 (https=)
WO (2) WO2010015900A1 (https=)

Families Citing this family (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US20080293637A1 (en) * 2007-05-23 2008-11-27 Allergan, Inc. Cross-linked collagen and uses thereof
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US20120071437A1 (en) 2007-07-30 2012-03-22 Allergan, Inc. Tunable crosslinked polysaccharide compositions
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
JP5670196B2 (ja) 2007-11-16 2015-02-18 バイセプト セラピューティクス、インク. 紫斑を治療する組成物および方法
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
US20130102563A1 (en) * 2008-08-04 2013-04-25 Allergan, Inc. Dermal filler with lidocaine
ES2658609T3 (es) 2008-09-02 2018-03-12 Tautona Group Lp Hilos de ácido hialurónico y/o derivados de los mismos, métodos para fabricar los mismos, y usos de los mismos
RU2514896C2 (ru) 2008-12-02 2014-05-10 Аллерган, Инк. Устройство для инъекций
IT1395392B1 (it) * 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110171310A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
AU2015234293B2 (en) * 2010-01-13 2017-04-27 Allergan Industrie Sas Stable hydrogel compositions including additives
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
KR101764451B1 (ko) 2010-03-12 2017-08-02 알러간 인더스트리 에스에이에스 피부 상태 개선을 위한 히알루론안 폴리머 및 만니톨을 포함하는 유체 조성물
EP3078388B1 (en) 2010-03-22 2019-02-20 Allergan, Inc. Cross-linked hydrogels for soft tissue augmentation
CA2805008C (en) * 2010-07-12 2015-05-12 Shin Poong Pharmaceutical Co., Ltd. Filler composition for tissue augmentation comprising a hydrogel of hyaluronic acid cross-linked with alkylene diamine
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
EP4616907A3 (en) * 2010-11-08 2025-11-12 Allergan Industries, SAS Soft tissue filler
FR2968305B1 (fr) 2010-12-06 2014-02-28 Teoxane Procede de preparation d'un gel reticule
ES2813498T3 (es) * 2011-01-06 2021-03-24 C Lowell Parsons Método para fabricar una composición que comprende un anestésico local, heparinoide y tampón
EP2663342B1 (en) * 2011-01-13 2020-03-25 Allergan, Inc. Stable hydrogel compositions including phenylephrine
EP2484387A1 (en) 2011-02-03 2012-08-08 Q-Med AB Hyaluronic acid composition
KR102073027B1 (ko) * 2011-04-05 2020-02-04 삼성전자 주식회사 반송파 집적 기술을 사용하는 무선통신시스템에서 복수 개의 타임 정렬 타이머 운용 방법 및 장치
EP2675491A2 (en) 2011-02-17 2013-12-25 Allergan, Inc. Compositions and improved soft tissue replacement methods
EP2606828B1 (en) * 2011-12-20 2018-04-11 Angioclinic AG Hyaluronic acid and its use for treating venous insufficiency and varicose veins
US20130096081A1 (en) * 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
KR102238406B1 (ko) 2011-06-03 2021-04-08 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
RU2613887C2 (ru) * 2011-08-10 2017-03-21 Гликорес 2000 С.Р.Л. Устойчивый к расщеплению сшитый низкомолекулярный гиалуронат
EP3590495A1 (en) 2011-08-25 2020-01-08 Allergan, Inc. Dermal filler compositions including antioxidants
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
CN108379112A (zh) 2011-09-14 2018-08-10 阿勒根公司 用于细纹治疗的真皮填充剂组合物
MX353955B (es) * 2011-10-11 2018-02-07 Allergan Holdings France Sas Hebras de acido hialuronico reticulado y metodos de uso de las mismas.
EP2581079B1 (en) * 2011-10-11 2016-12-07 BioPolymer GmbH & Co. KG Combination of hyaluronic acid and prilocaine
KR20210071106A (ko) 2011-12-08 2021-06-15 알러간 인더스트리 에스에이에스 진피 필러 조성물
CN102552974A (zh) * 2012-02-17 2012-07-11 上海白衣缘生物工程有限公司 皮肤注射填充用凝胶组合物及其制备
BR112014031412B1 (pt) * 2012-06-15 2021-01-05 Merz Pharma Gmbh & Co. Kgaa método de preparação de uma composição
DK2874598T3 (en) * 2012-07-18 2018-03-05 Allergan Ind Sas HYALURONIC ACID FORMULATION CONTAINING PYRUVATE
CH705713B1 (de) * 2012-09-21 2013-05-15 Labo Cosprophar Ag Dermokosmetische Zusammensetzung zur topischen Anwendung.
CA2886115A1 (en) 2012-10-02 2014-04-10 Allergan, Inc. Dermal filler hydrogels with vitamin a/cyclodextrin inclusion complexes
WO2014055895A1 (en) 2012-10-05 2014-04-10 Allergan, Inc. Injectable device and method for sculpting, augmenting or correcting facial features such as the chin
US20140124514A1 (en) * 2012-11-08 2014-05-08 Onpharma, Inc. Method and apparatus for adding buffers and other substances to medical cartridges
US9907740B2 (en) 2013-01-17 2018-03-06 Jeffrey Hagel Increasing muscular volume in a human using hyaluronic acid
SG11201505853RA (en) * 2013-01-28 2015-08-28 C Lowell Parsons Stable compositions comprising heparinoid, acute-acting anesthetic, and buffer
CN105377183B (zh) 2013-03-08 2020-07-07 厄耳他拉登脱产品股份有限公司 蜡基组合物,其制品及制造和使用方法
FR3006689A1 (fr) * 2013-06-11 2014-12-12 Benedicte Vincente Tauzin Procede de reticulation de l'acide hyaluronique; procede de preparation d'un hydrogel injectable; hydrogel obtenu; utilisation de l'hydroget obtenu
CN104225677B (zh) * 2013-06-13 2016-09-21 山东省生物药物研究院 交联透明质酸细胞支架材料及其制备方法和应用
EP3007708A2 (en) * 2013-06-14 2016-04-20 Galderma S.A. Ha with cyclodextrins
WO2015005345A1 (ja) * 2013-07-08 2015-01-15 電気化学工業株式会社 コアシェル型架橋ヒアルロン酸ゲル粒子、その製造方法及び医用材料
US9421198B2 (en) 2013-07-30 2016-08-23 Teoxane Composition comprising hyaluronic acid and mepivacaine
LT3049055T (lt) * 2013-09-27 2018-07-25 Anteis S.A. Injekcinio hidrogelio, sterilizuoto karščiu, sudaryto iš hialurono rūgšties, turinčio miltelių pavidalo lidokaino ir šarminio agento, gamybos būdas
US10047172B2 (en) 2013-09-30 2018-08-14 Galderma S.A. Single step functionalization and cross-linking of hyaluronic acid
AU2014332534B2 (en) 2013-10-11 2019-08-08 Ultradent Products, Inc. Wax-based compositions, articles made therefrom, and methods of manufacture and use
KR102133526B1 (ko) * 2013-10-31 2020-07-13 삼성전자주식회사 USB 어플리케이션 데이터의 QoS를 고려한 무선 전송 지원 기법
US20150141910A1 (en) * 2013-11-14 2015-05-21 University Medical Pharmaceuticals Corporation Microneedles for therapeutic agent delivery with improved mechanical properties
FR3015290B1 (fr) * 2013-12-23 2017-01-13 Lab Vivacy Compositions d'acide hyaluronique compreant de la mepivacaine
WO2015112907A1 (en) * 2014-01-27 2015-07-30 Allergan Holdings France S.A.S. Spherical forms of cross-linked hyaluronic acid and methods of use thereof
CA2944201A1 (en) 2014-04-01 2015-10-08 Klox Technologies Inc. Tissue filler compositions and methods of use
AR099900A1 (es) * 2014-04-01 2016-08-24 Merz Pharma Gmbh & Co Kgaa Rellenos para tejidos blandos con polisacáridos con persistencia mejorada, kit, procedimiento, uso
EP3126008B1 (en) * 2014-04-02 2020-08-05 Merz Pharma GmbH & Co. KGaA In vivo degradation of polysaccharide-containing fillers
US20150297492A1 (en) * 2014-04-22 2015-10-22 Allergan, Inc. Dry dermal filler compositions and methods of reconstitution
EP3200838B1 (en) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stable hydrogel compositions including additives
EP3203990A4 (en) * 2014-10-08 2018-09-05 Andreas Voigt Cross-linked biopolymer macroscopic systems and method of making same
EP3204017A4 (en) * 2014-10-08 2018-06-27 Andreas Voigt Micronized hydrophilic cross-linked biopolymer systems and method of making same
TWI716365B (zh) * 2014-11-13 2021-01-21 德商梅茲製藥有限兩合公司 注射型真皮填充劑組合物及其套組、製備方法、與使用
EA035551B1 (ru) 2014-12-02 2020-07-06 Силк Терапьютикс, Инк. Изделие
FR3029928B1 (fr) 2014-12-15 2018-03-09 Teoxane Gel reticule
CN107427604B (zh) * 2015-01-16 2021-07-09 脊柱康健公司 治疗椎间盘的方法
CN105878051B (zh) * 2015-01-26 2019-02-26 华熙福瑞达生物医药有限公司 蜂巢状透明质酸及其制备方法
CN107427584A (zh) 2015-01-28 2017-12-01 阿勒根公司 关节脂肪垫制剂及其使用方法
WO2016128783A1 (en) * 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
HUE047971T2 (hu) * 2015-02-13 2020-05-28 Allergan Ind Sas Az arcelemek - például az áll - formázására, megnagyobbítására vagy korrekciójára szolgáló implantátumok
WO2016132167A1 (en) * 2015-02-16 2016-08-25 Allergan Industrie, Sas Implants for sculpting, augmenting or correcting facial features such as the chin
ES2902978T3 (es) 2015-02-13 2022-03-30 Endo Derma Co Ltd Microestructura que usa un hidrogel de ácido hialurónico reticulado y método para producir la misma
US10004824B2 (en) 2015-05-11 2018-06-26 Laboratoires Vivacy Compositions comprising at least one polyol and at least one anesthetic
FR3036035B1 (fr) 2015-05-11 2018-10-05 Laboratoires Vivacy Compositions comprenant au moins un polyol et au moins un anesthesique
FR3037797B1 (fr) 2015-06-24 2018-08-17 Kylane Laboratoires Sa Procede de preparation d'un hydrogel reticule injectable; hydrogel obtenu; utilisation de l'hydrogel obtenu
US10836840B2 (en) * 2015-06-30 2020-11-17 Merz Pharma Gmbh & Co. Kgaa Method for producing crosslinked hyaluronic acid
EP3316911B1 (en) 2015-06-30 2020-11-04 Merz Pharma GmbH & Co. KGaA Method of preparing a composition based on hyaluronic acid
AU2016294611B2 (en) 2015-07-14 2022-08-11 Evolved By Nature, Inc. Silk performance apparel and products and methods of preparing the same
EP3328351A1 (en) 2015-07-27 2018-06-06 Galderma S.A. A process for efficient cross-linking of hyaluronic acid
CN105131348B (zh) * 2015-08-19 2018-01-16 李媚 一种无菌可注射材料
CN105107018B (zh) * 2015-08-19 2018-08-24 李媚 一种无菌可注射材料的制备方法
KR101720426B1 (ko) 2015-09-01 2017-04-14 (주)시지바이오 히알루론산 조성물 및 그의 제조방법
EP3162813A1 (en) 2015-11-02 2017-05-03 Merz Pharma GmbH & Co. KGaA Process for depleting epoxide species in crosslinked poly-saccharide gel compositions and compositions obtained thereby
MX2018005846A (es) 2015-11-10 2019-07-18 E Perito Paul Sistema y metodo para el aumento no quirurgico de la circunferencia peniana.
US10456347B2 (en) 2015-11-24 2019-10-29 Bmi Korea Co., Ltd Composition for injection of hyaluronic acid, containing hyaluronic acid derivative and DNA fraction, and use thereof
FR3044557B1 (fr) 2015-12-07 2017-12-01 Benedicte Vincente Gavard Molliard Tauzin Nouvelle composition injectable; procede de preparation de ladite composition; utilisation de ladite composition
KR102139337B1 (ko) 2016-03-17 2020-07-29 주식회사 엘지생활건강 미세바늘패치를 이용한 히알루론산 필러
TWI727014B (zh) * 2016-03-24 2021-05-11 德商梅茲製藥有限兩合公司 修飾透明質酸與其製造方法及其用途
KR101660211B1 (ko) * 2016-06-07 2016-09-26 동국제약 주식회사 단일상과 이성상의 특성을 동시에 갖는 히알루론산 가교체, 이의 제조 방법 및 이의 용도
US20200054786A1 (en) 2016-10-13 2020-02-20 Allergan, Inc. Coacervate hyaluronan hydrogels for dermal filler applications
FR3058064B1 (fr) 2016-10-28 2020-08-07 Lab Vivacy Composition a base d'acide hyaluronique comprenant de la mepivacaine
EP3538066B1 (en) * 2016-11-11 2021-12-29 Anteis SA Hyaluronic acid dermal fillers crosslinked with citric acid, method for making same and uses thereof
KR101879065B1 (ko) * 2016-12-12 2018-07-17 구태훈 구형 입자를 갖는 연조직용 필러 및, 그 제조방법
KR101922711B1 (ko) * 2016-12-28 2018-11-27 주식회사 유영제약 가교된 히알루론산겔의 정제 방법
KR102363007B1 (ko) * 2017-01-18 2022-02-14 구태훈 모노-페이직 ha 필러의 특성과 바이-페이직 ha 필러의 특성을 함께 갖는 ha 필러, 필러 주입에 사용되는 주사기 및, 필러의 제조방법
EP3590546B1 (en) * 2017-02-28 2024-08-21 CG Bio Co., Ltd. Composition for skin injection
BR112019017793B1 (pt) * 2017-02-28 2022-12-06 Cg Bio Co., Ltd. Composição para injeção dérmica
US11123455B2 (en) 2017-02-28 2021-09-21 Cg Bio Co., Ltd. Composition for dermal injection
SG10202107829YA (en) 2017-03-22 2021-08-30 Genentech Inc Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
KR101917026B1 (ko) 2017-03-24 2019-01-24 박원진 피부 주름 개선 또는 예방용 화장료 조성물
JP2020516695A (ja) 2017-04-12 2020-06-11 ウリゲン ファーマシューティカルズ、インコーポレイテッド 改善された安定性を備えた注射器中に局所麻酔薬、緩衝液、およびグルコサミノグリカンを含む製品
AU2018290810C1 (en) * 2017-06-26 2024-09-12 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue fillers and methods of using the same
US20230190997A1 (en) * 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
WO2019067745A1 (en) 2017-09-27 2019-04-04 Silk, Inc. SILK-COATED FABRICS, PRODUCTS AND PREPARATION METHODS THEREFOR
WO2019079672A1 (en) 2017-10-19 2019-04-25 Lifecell Corporation ACELLULAR TISSUE MATRIX PRODUCTS FLUIDS AND METHODS OF PRODUCTION
KR102091452B1 (ko) * 2017-12-19 2020-03-20 대화제약 주식회사 국소 마취제 및 히알루론산 하이드로겔을 포함하는 사전충전형 주사기의 제조방법
US11530302B2 (en) * 2017-12-29 2022-12-20 Matex Lab S.P.A. Method to prepare a filler with a hyaluronic acid base using specific crosslinking agents
KR102524418B1 (ko) * 2017-12-29 2023-04-24 마텍스 랩 에스.피.에이 중화 단계를 포함하고 히알루론산 염기를 가지는 필러를 제조하는 방법
EP3731808B1 (en) * 2017-12-29 2023-09-20 Matex Lab S.P.A. Method to prepare filler with a hyaluronic acid base comprising a neutralization step
IT201800001890A1 (it) 2018-01-25 2019-07-25 Fidia Farm Spa Composizioni farmaceutiche per il trattamento del dolore postoperatorio
CA3099732A1 (en) 2018-05-09 2019-11-14 The Johns Hopkins University Nanofiber-hydrogel composites for cell and tissue delivery
ES3060255T3 (en) 2018-05-09 2026-03-25 Univ Johns Hopkins Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration
CN108653817B (zh) * 2018-05-24 2021-02-02 上海其胜生物制剂有限公司 一种新型胶原刺激剂的制备方法
EP3804769B1 (en) * 2018-07-06 2025-05-21 Lg Chem, Ltd. Hyaluronic acid filler having high viscoelasticity and high cohesiveness
EP3804770B1 (en) * 2018-07-10 2023-12-06 Lg Chem, Ltd. Hyaluronic acid filler having high lift capacity and low injection force
WO2020030629A1 (en) * 2018-08-07 2020-02-13 Merz Pharma Gmbh & Co. Kgaa Method for dynamic filtration of a cross-linked hydrogel
KR20200046649A (ko) 2018-10-25 2020-05-07 (주)뉴크레이티브랩 혼합상 히알루론산 제조방법
AU2019405953B2 (en) 2018-12-19 2025-09-18 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same
RS67193B1 (sr) * 2018-12-20 2025-10-31 Lg Chemical Ltd Filer sa odličnim svojstvima filera koji obuhvata hidrogel hijaluronske kiseline
CN113226388B (zh) * 2018-12-21 2023-07-25 株式会社Lg化学 具有优异的填充性能的包含透明质酸水凝胶的填充剂
US20220160934A1 (en) * 2019-03-24 2022-05-26 Allergan Pharmaceuticals International Limited Injectable homogeneous gels comprising multiple forms of hyaluronic acid and methods for manufacturing thereof
CA3140715A1 (en) * 2019-05-17 2020-11-26 The Governing Council Of The University Of Toronto Sustained release local anesthetic hydrogel composition
IT201900021693A1 (it) * 2019-11-20 2021-05-20 Bmg Pharma S P A Derivati butirrati o butirrati e formiati dell’acido ialuronico reticolati e loro procedimento di reticolazione
KR102566288B1 (ko) * 2019-12-24 2023-08-11 주식회사 엘지화학 마취제, 완충 용액 및 히알루론산 하이드로겔을 포함하는 주사용 조성물 및 이의 제조방법
KR102173790B1 (ko) 2020-02-26 2020-11-03 (주) 제이피케어즈 가교 히알루론산을 이용한 약물 전달 조성물 및 이의 제조방법
US11058640B1 (en) 2020-04-07 2021-07-13 Amc Group, Llc Hyaluronate compositions and soft tissue fillers
FR3109153B1 (fr) * 2020-04-10 2022-07-15 Teoxane SA Compositions à base d’au moins deux glycosaminoglycanes
WO2021212097A1 (en) * 2020-04-17 2021-10-21 Brendan Patrick Purcell Controlled release hyaluronic acid compositions
KR102417671B1 (ko) * 2020-04-28 2022-07-06 충남대학교산학협력단 자가가교 시스템을 가지는 히알루론산 기반 연조직 충전 조성물 및 이의 제조방법
KR102425496B1 (ko) 2020-05-08 2022-07-26 주식회사 종근당 고탄성, 고점도 및 고유효 가교율을 갖는 히알루론산 가교체, 및 이의 제조방법
FR3111903B1 (fr) 2020-06-24 2022-12-02 Lab Vivacy Procede d’incorporation de composes organiques en solution au sein d’un hydrogel
CN111643730A (zh) * 2020-07-14 2020-09-11 华熙生物科技股份有限公司 注射用交联透明质酸凝胶的制备方法及应用
WO2023080886A1 (en) * 2020-09-29 2023-05-11 Ziropa, Inc. Compositions and methods for pain relief and numbing
JP2024519426A (ja) * 2020-09-29 2024-05-14 ジロパ・インコーポレイテッド 疼痛の緩和及び麻痺のための組成物及び方法
TR202101065A1 (tr) * 2021-01-25 2022-08-22 Hacettepe Ueniversitesi Hyaluroni̇k asi̇t jel i̇çeren bi̇r doku dolgu malzemesi̇ ve üreti̇m yöntemi̇
KR102581434B1 (ko) * 2021-02-09 2023-09-22 (주)제테마 히알루론산 필러 조성물의 제조에 사용되는 용액 및 이를 이용한 히알루론산 필러 조성물
CN113449476B (zh) * 2021-07-08 2022-07-05 浙江大学 基于Stacking的脱丁烷塔中丁烷含量软测量方法
KR102348467B1 (ko) * 2021-07-14 2022-01-07 주식회사 휴메딕스 Dna 분획물을 포함하는 필러 제조방법 및 이로부터 제조된 필러
KR102640893B1 (ko) * 2021-11-12 2024-02-27 주식회사 유영제약 히알루론산 가교물을 포함하는 조성물의 제조방법
CN116212108B (zh) * 2023-04-18 2023-10-20 杭州科腾生物制品有限公司 一种含利多卡因的双层交联凝胶及其制备方法和应用
WO2024250012A2 (en) 2023-06-02 2024-12-05 33 Medical, Inc. Compositions for treatment of discogenic pain, and processes for making and using the same
EP4704809B1 (en) 2024-04-03 2026-04-15 Nordic Group B.V. Hyaluronic acid-based compositions for use in dry eye treatment

Family Cites Families (270)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2128827A (en) 1938-03-09 1938-08-30 Frank B Killian Method and apparatus for manufacturing thin rubber articles
CA807629A (en) 1966-06-30 1969-03-04 Colgate-Palmolive Company Lotion and detergent compositions
JPS4838158B1 (https=) 1970-10-05 1973-11-15
CA949965A (en) 1971-12-03 1974-06-25 Robert H. Marchessault Method of preparing cross-linked starch and starch derivatives
US3769009A (en) * 1971-12-29 1973-10-30 Xerox Corp Inking system for liquid particle migration on automatic machines
US3949073A (en) 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
US4233360A (en) 1975-10-22 1980-11-11 Collagen Corporation Non-antigenic collagen and articles of manufacture
CA1073360A (en) * 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
JPS581933Y2 (ja) 1979-04-23 1983-01-13 株式会社日本製鋼所 ケ−ブルのクランプ装置
JPS55153711A (en) 1979-05-19 1980-11-29 Pola Chem Ind Inc Cosmetic lotion
US4279812A (en) * 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen
JPS6052129B2 (ja) * 1979-10-04 1985-11-18 呉羽化学工業株式会社 医療用コラ−ゲン繊維の製造法
US4424208A (en) 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4582640A (en) * 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4501306A (en) 1982-11-09 1985-02-26 Collagen Corporation Automatic syringe filling system
SE442820B (sv) 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
SE456346B (sv) 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4636524A (en) 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4605691A (en) * 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4582865A (en) 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE8501022L (sv) 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US4713448A (en) 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
SE452469B (sv) 1986-06-18 1987-11-30 Pharmacia Ab Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma
US4803075A (en) 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
FR2608456B1 (fr) 1986-12-18 1993-06-18 Mero Rousselot Satia Microcapsules a base de gelatine et de polysaccharides et leur procede d'obtention
US5091171B2 (en) 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US5385938B1 (en) 1986-12-23 1997-07-15 Tristrata Inc Method of using glycolic acid for treating wrinkles
US5079236A (en) 1987-05-27 1992-01-07 Hyal Pharmaceutical Corporation Pure, sterile, pyrogen-free hyaluronic acid formulations their methods of preparation and methods of use
FR2623167B2 (fr) 1987-08-14 1992-08-07 Genus Int Perfectionnement aux articles munis d'articulations elastiques se rigidifiant lors de leur mise en tension
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
IT1219587B (it) 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5643464A (en) 1988-11-21 1997-07-01 Collagen Corporation Process for preparing a sterile, dry crosslinking agent
US5565519A (en) 1988-11-21 1996-10-15 Collagen Corporation Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5614587A (en) * 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
SE462587B (sv) 1988-11-30 1990-07-23 Wiklund Henry & Co Anordning vid maerkning av arbetsstycken med skrift- eller andra tecken
JPH02215707A (ja) 1989-02-15 1990-08-28 Chisso Corp 皮膚化粧料
ATE123306T1 (de) * 1989-05-19 1995-06-15 Hayashibara Biochem Lab Alpha-glycosyl-l-ascorbinsäure und ihre herstellung und verwendungen.
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
EP0416250A3 (en) 1989-08-01 1991-08-28 The Research Foundation Of State University Of New York N-acylurea and o-acylisourea derivatives of hyaluronic acid
CA2023922A1 (en) 1989-09-05 1991-03-06 James M. Curtis Method of manufacturing an implantable article provided with a micropillared surface
JP2832848B2 (ja) 1989-10-21 1998-12-09 株式会社林原生物化学研究所 結晶2―O―α―D―グルコピラノシル―L―アスコルビン酸とその製造方法並びに用途
US4996787A (en) * 1990-05-29 1991-03-05 Jack N. Holcomb SigSauer pistol with concealed radio transmitter
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5246698A (en) 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5283671A (en) * 1991-02-20 1994-02-01 Stewart John R Method and apparatus for converting RGB digital data to optimized CMYK digital data
JP3115625B2 (ja) 1991-03-30 2000-12-11 帝國製薬株式会社 リドカイン含有外用貼付剤
US5314874A (en) 1991-04-19 1994-05-24 Koken Co., Ltd. Intracorporeally injectable composition for implanting highly concentrated cross-linked atelocollagen
DE4200080A1 (de) 1992-01-03 1993-09-30 Reinmueller Johannes Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung
PT632820E (pt) 1992-02-28 2000-11-30 Collagen Corp Composicoes de colagenio homogeneizado de alta concentracao
IT1260154B (it) 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
AU694413B2 (en) 1993-01-20 1998-07-23 Convatec Technologies Inc. Fibres
WO1994021299A1 (en) * 1993-03-19 1994-09-29 Medinvent A composition and a method for tissue augmentation
US5531716A (en) 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US5616568A (en) 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
CA2146090C (en) 1994-05-10 1998-11-24 Mark E. Mitchell Apparatus and method of mixing materials in a sterile environment
US5616689A (en) * 1994-07-13 1997-04-01 Collagen Corporation Method of controlling structure stability of collagen fibers produced form solutions or dispersions treated with sodium hydroxide for infectious agent deactivation
AU706434B2 (en) 1994-10-18 1999-06-17 Ethicon Inc. Injectable liquid copolymers for soft tissue repair and augmentation
US20050186673A1 (en) 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US5612027A (en) 1995-04-18 1997-03-18 Galin; Miles A. Controlled release of miotic and mydriatic drugs in the anterior chamber
US5972326A (en) 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
FR2733427B1 (fr) 1995-04-25 2001-05-25 W K Et Associes Compositions biphasiques injectables renfermant de l'acide hyaluronique, notamment utiles en chirurgies reparatrice et esthetique
FR2733426B1 (fr) 1995-04-25 1997-07-18 Debacker Yves Dispositif medical pour le comblement des deformations du volume de la peau telles que rides et cicatrices par injection de 2 formes physico-chimiques differentes d'un polymere biologique
US6284284B1 (en) 1995-06-06 2001-09-04 Advanced Tissue Sciences, Inc. Compositions and methods for production and use of an injectable naturally secreted extracellular matrix
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
US5571503A (en) 1995-08-01 1996-11-05 Mausner; Jack Anti-pollution cosmetic composition
US6007843A (en) * 1995-09-29 1999-12-28 Lam Pharmaceuticals Corp. Sustained release delivery system
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
IT1277707B1 (it) * 1995-12-22 1997-11-11 Chemedica Sa Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare
US5980948A (en) 1996-08-16 1999-11-09 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
IT1287967B1 (it) * 1996-10-17 1998-09-10 Fidia Spa In Amministrazione S Preparazioni farmaceutiche per uso anestetico locale
FR2759576B1 (fr) 1997-02-17 1999-08-06 Corneal Ind Implant de sclero-keratectomie pre-descemetique
FR2759577B1 (fr) 1997-02-17 1999-08-06 Corneal Ind Implant de sclerectomie profonde
US5935164A (en) * 1997-02-25 1999-08-10 Pmt Corporaton Laminated prosthesis and method of manufacture
FR2764514B1 (fr) * 1997-06-13 1999-09-03 Biopharmex Holding Sa Implant injectable en sous-cutane ou intradermique a bioresorbabilite controlee pour la chirurgie reparatrice ou plastique et la dermatologie esthetique
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US6391336B1 (en) 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
FR2778336A1 (fr) 1998-05-11 1999-11-12 Jean Pierre Perraud Implant injectable en sous-cutane et en sous-gingival resorbable a base de maltodextrine micro-encapsulee et resorbable en un temps determine
FR2780730B1 (fr) 1998-07-01 2000-10-13 Corneal Ind Compositions biphasiques injectables, notamment utiles en chirurgies reparatrice et esthetique
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
IT1303738B1 (it) 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
IT1303735B1 (it) 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S Acidi ialuronici reticolati e loro usi medici.
US20020016637A1 (en) * 1998-12-16 2002-02-07 Mark A. Anton Soft tissue filler
DK172900B1 (da) 1998-12-18 1999-09-27 Per Julius Nielsen Præparat samt kit til brug ved intraoculære operationer
GB9902412D0 (en) 1999-02-03 1999-03-24 Fermentech Med Ltd Process
GB9902652D0 (en) 1999-02-05 1999-03-31 Fermentech Med Ltd Process
US6767928B1 (en) 1999-03-19 2004-07-27 The Regents Of The University Of Michigan Mineralization and biological modification of biomaterial surfaces
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
WO2001044869A1 (en) * 1999-12-16 2001-06-21 Nikon Corporation Bayonet mount
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US6682760B2 (en) 2000-04-18 2004-01-27 Colbar R&D Ltd. Cross-linked collagen matrices and methods for their preparation
KR20010096388A (ko) * 2000-04-19 2001-11-07 진세훈 귀두확대성형재료 및 이 재료를 이용한 귀두의 확대시술방법
FR2811671B1 (fr) 2000-07-17 2003-02-28 Corneal Ind Hydrogel de polymere(s), resistant a la biodegration, preparation et utilisation a titre de support de regeneration tissulaire
FR2811996B1 (fr) 2000-07-19 2003-08-08 Corneal Ind Reticulation de polysaccharide(s), preparation d'hydrogel(s) ; polysaccharide(s) et hydrogel(s) obtenus,leurs utilisations
ATE392907T1 (de) 2000-07-28 2008-05-15 Anika Therapeutics Inc Bioabsorbierbare kompositmaterialien aus derivatisierter hyaluronsäure
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US6773723B1 (en) 2000-08-30 2004-08-10 Depuy Acromed, Inc. Collagen/polysaccharide bilayer matrix
JP4187917B2 (ja) 2000-09-08 2008-11-26 独立行政法人科学技術振興機構 組織再生マトリックス用グリコサミノグリカン−コラーゲン複合体の製造方法
US6924273B2 (en) * 2000-10-03 2005-08-02 Scott W. Pierce Chondroprotective/restorative compositions and methods of use thereof
JP2004510730A (ja) 2000-10-06 2004-04-08 ヤゴテック アーゲー 非経口的投与可能な制御放出微粒子調製物
KR100375299B1 (ko) 2000-10-10 2003-03-10 주식회사 엘지생명과학 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법
AU2001298061A1 (en) 2000-12-13 2003-07-09 Purdue Research Foundation Microencapsulation of drugs by solvent exchange
US6979440B2 (en) 2001-01-29 2005-12-27 Salvona, Llc Compositions and method for targeted controlled delivery of active ingredients and sensory markers onto hair, skin, and fabric
US7119062B1 (en) 2001-02-23 2006-10-10 Neucoll, Inc. Methods and compositions for improved articular surgery using collagen
WO2002087645A1 (en) * 2001-05-01 2002-11-07 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions
TW574301B (en) 2001-05-02 2004-02-01 Ind Tech Res Inst Manufacturing method of epoxide crosslinked polysaccharides matrix
US20050227936A1 (en) 2001-05-18 2005-10-13 Sirna Therapeutics, Inc. RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)
MXPA04000156A (es) * 2001-06-29 2005-06-06 Medgraft Microtech Inc Implantes inyectables biodegradables y metodos relacionados de fabricacion y uso.
US6749841B2 (en) * 2001-07-26 2004-06-15 Revlon Consumer Products Corporation Stabilized aqueous acidic antiperspirant compositions and related methods
JP4230135B2 (ja) 2001-08-21 2009-02-25 独立行政法人科学技術振興機構 多官能性架橋剤によって架橋したグリコサミノグリカン−コラーゲン複合体の製造法
US20060189516A1 (en) 2002-02-19 2006-08-24 Industrial Technology Research Institute Method for producing cross-linked hyaluronic acid-protein bio-composites
JP3916516B2 (ja) 2002-06-10 2007-05-16 独立行政法人科学技術振興機構 硬組織−軟組織界面再生用足場材料
US6780366B2 (en) 2002-08-15 2004-08-24 Mentor Corporation Drip retainer
KR100523953B1 (ko) 2002-08-27 2005-10-25 주식회사 엘지생명과학 천연다당류와 히알루론산의 마이크로비드 및 이의 제조 방법
KR100507545B1 (ko) 2002-09-03 2005-08-09 주식회사 엘지생명과학 히알루론산 유도체 및 그의 제조방법
US20040127932A1 (en) 2002-09-12 2004-07-01 Shah Tilak M. Dip-molded polymeric medical devices with reverse thickness gradient, and method of making same
DE10246340A1 (de) 2002-10-04 2004-04-29 Wohlrab, David, Dr. Kombinationspräparat aus Hyaluronsäure und mindestens einem Lokalanästhetikum und dessen Verwendung
US20040101959A1 (en) * 2002-11-21 2004-05-27 Olga Marko Treatment of tissue with undifferentiated mesenchymal cells
AU2003300022A1 (en) 2002-12-30 2004-07-29 Angiotech International Ag Silk-containing stent graft
TWI251596B (en) 2002-12-31 2006-03-21 Ind Tech Res Inst Method for producing a double-crosslinked hyaluronate material
AU2003206922A1 (en) 2003-02-19 2004-09-09 Aventis Pharmaceuticals Holdings Inc. Composition and method for intradermal soft tissue augmentation
EP1606009A2 (en) 2003-03-25 2005-12-21 BioCure, Inc. Hydrogel string medical device
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
AU2003901834A0 (en) 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
JP2004323453A (ja) 2003-04-25 2004-11-18 Chisso Corp 分解性ゲル及びその製造法
KR100931551B1 (ko) 2003-05-13 2009-12-14 미마스 한도타이 고교 가부시키가이샤 웨이퍼 디마운트 방법, 웨이퍼 디마운트 장치 및 웨이퍼디마운트 이송기
DE10323794A1 (de) * 2003-05-23 2004-12-09 Dr. Suwelack Skin & Health Care Ag Verfahren zur Herstellung von Alginat-haltigen porösen Formkörpern
JP2007500027A (ja) * 2003-07-30 2007-01-11 アンタイス エス.エイ. 生物医学的な使用のための複合マトリックス
JP4511470B2 (ja) 2003-10-29 2010-07-28 帝人株式会社 ヒアルロン酸化合物、そのハイドロゲルおよび関節軟骨損傷治療用材料
US20050148512A1 (en) 2003-11-10 2005-07-07 Angiotech International Ag Medical implants and fibrosis-inducing agents
US20070224278A1 (en) * 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
US20060141049A1 (en) * 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20090148527A1 (en) * 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
CA2536192A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Soft tissue implants and anti-scarring agents
US8124120B2 (en) 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
US8524213B2 (en) 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
CA2550718C (en) 2003-12-30 2013-11-05 Genzyme Corporation Cohesive gels from cross-linked hyaluronan and/or hylan, their preparation and use
DE102004002001A1 (de) * 2004-01-14 2005-08-11 Reinmüller, Johannes, Dr.med. Mittel zur Behandlung von entzündlichen Erkrankungen
US7552442B1 (en) 2004-01-27 2009-06-23 Honeywell International Inc. Military data link integration apparatus and method
CA2536096A1 (en) 2004-01-30 2005-08-18 Angiotech International Ag Compositions and methods for treating contracture
FR2865737B1 (fr) 2004-02-03 2006-03-31 Anteis Sa Gel reticule biocompatible
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US8288362B2 (en) * 2004-05-07 2012-10-16 S.K. Pharmaceuticals, Inc. Stabilized glycosaminoglycan preparations and related methods
WO2005113608A1 (en) 2004-05-20 2005-12-01 Mentor Corporation Method of covalently linking hyaluronan and chitosan
EP1750769B1 (en) * 2004-05-20 2013-01-23 Mentor Worldwide LLC Methods for making injectable polymer hydrogels
US20050287180A1 (en) 2004-06-15 2005-12-29 Chen Andrew X Phospholipid compositions and methods for their preparation and use
US20080124400A1 (en) 2004-06-24 2008-05-29 Angiotech International Ag Microparticles With High Loadings Of A Bioactive Agent
AU2005272578A1 (en) * 2004-08-13 2006-02-23 Angiotech International Ag Compositions and methods using hyaluronic acid and hyluronidase inhibitors
US20060040895A1 (en) 2004-08-19 2006-02-23 Kipling Thacker Aesthetic use of hyaluronan
US20060058238A1 (en) * 2004-09-15 2006-03-16 Lee Laurent-Applegate Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
US7414021B2 (en) 2004-10-01 2008-08-19 Vincent Carmine Giampapa Method and composition for restoration of age related tissue loss in the face or selected areas of the body
KR100762928B1 (ko) * 2004-10-29 2007-10-04 재단법인서울대학교산학협력재단 견 피브로인 나노섬유로 이루어진 부직포 형태의 골조직유도 재생용 차폐막 및 그 제조방법
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
CN101107270B (zh) 2004-11-24 2011-11-23 诺维信生物制药丹麦公司 用二乙烯基砜交联透明质酸的方法
FR2878444B1 (fr) 2004-11-30 2008-04-25 Corneal Ind Soc Par Actions Si Solutions viscoelastiques renfermant du hyaluronate de sodiu et de l'hydroxypropylmethylcellulose, preparation et utilisations
WO2006067608A1 (en) 2004-12-22 2006-06-29 Laboratoire Medidom S.A. Aqueous formulations based on sodium hyaluronate for parenteral use
WO2006102676A1 (en) 2005-03-23 2006-09-28 Tissue Engineering Refraction, Inc. Injectable polyethylene oxide dermal fillers and related devices
EP1893174A2 (en) 2005-05-10 2008-03-05 Cytophil, Inc. Injectable hydrogels and methods of making and using same
EP1726299A3 (en) 2005-05-27 2007-04-18 StratoSphere Pharma AB Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
US7491709B2 (en) 2005-07-01 2009-02-17 Wayne Carey Treatment with hyaluronic acid
WO2007018124A1 (ja) 2005-08-11 2007-02-15 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo コラーゲン産生増強剤とその用途
JP4982718B2 (ja) 2005-08-31 2012-07-25 株式会社林原 美肌用の経口摂取用組成物
CA2876767C (en) * 2005-10-03 2018-07-10 Mark A. Pinsky Liposomes comprising hyaluronic acid and their use in improved skin care
CA2633957A1 (en) 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid
CA2633978A1 (en) 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Bioabsorbable implant of hyaluronic acid derivative for treatment of osteochondral and chondral defects
FR2894827B1 (fr) * 2005-12-21 2010-10-29 Galderma Res & Dev Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation,et leurs utilisations
FR2895907B1 (fr) 2006-01-06 2012-06-01 Anteis Sa Gel viscoelastique a usage dermatologique
US20070184087A1 (en) 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US20070212385A1 (en) 2006-03-13 2007-09-13 David Nathaniel E Fluidic Tissue Augmentation Compositions and Methods
US20070218102A1 (en) 2006-03-15 2007-09-20 Surmodics, Inc. Biodegradable hydrophobic polysaccharide-based coatings
FR2900575B1 (fr) * 2006-05-05 2008-10-17 Anteis Sa Gel biocompatible a liberation controlee, son procede de preparation et son utilisation
EP2543340A1 (en) 2006-05-19 2013-01-09 Trustees Of Boston University Novel hydrophilic polymers as medical lubricants and gels
US20070298005A1 (en) 2006-06-22 2007-12-27 Marie-Josee Thibault Injectable composition for treatment of skin defects or deformations
WO2008003321A2 (en) 2006-07-07 2008-01-10 Novozymes Biopolymer A/S Compositions with several hyaluronic acid fractions for cosmetic use
JP4557939B2 (ja) 2006-07-18 2010-10-06 株式会社ジェイテック X線ミラーの高精度姿勢制御法およびx線ミラー
US20100035838A1 (en) 2006-09-19 2010-02-11 Geoffrey Kenneth Heber Cross-linked polysaccharide gels
FR2908415B1 (fr) 2006-11-10 2009-01-23 Abr Dev Sarl Acide hyaluronique reticule et son procede de preparation
FR2909560B1 (fr) * 2006-12-06 2012-12-28 Fabre Pierre Dermo Cosmetique Gel d'acide hyaluronique pour injection intradermique
CA2672495C (en) 2006-12-11 2017-01-17 Chi2Gel Ltd. Novel injectable chitosan mixtures forming hydrogels
KR100759091B1 (ko) 2006-12-13 2007-09-17 조강선 피부 충전제 조성물
CN101622017B (zh) 2006-12-22 2018-09-11 克罗马制药有限责任公司 聚合物的用途
WO2008088922A2 (en) 2007-01-19 2008-07-24 Genentech, Inc. Prevention of hydrogel viscosity loss
WO2008098007A1 (en) 2007-02-05 2008-08-14 Freedom-2, Inc. Tissue fillers and methods of using the same
CN101677957A (zh) 2007-02-05 2010-03-24 卡比兰生物外科公司 用于递送生物活性试剂的聚合物制剂
US7776840B2 (en) 2007-02-21 2010-08-17 Cutanea Life Sciences, Inc. Methods of use of biomaterial and injectable implant containing biomaterial
US7939578B2 (en) 2007-02-23 2011-05-10 3M Innovative Properties Company Polymeric fibers and methods of making
US8642067B2 (en) 2007-04-02 2014-02-04 Allergen, Inc. Methods and compositions for intraocular administration to treat ocular conditions
US11078262B2 (en) 2007-04-30 2021-08-03 Allergan, Inc. High viscosity macromolecular compositions for treating ocular conditions
US20100323985A1 (en) 2007-05-11 2010-12-23 Marc Moutet Pharmaceutical or cosmetic preparations for topical and/or parenteral application, preparation methods thereof and use of same
WO2008148967A2 (fr) 2007-05-11 2008-12-11 Galderma Research & Development Preparations pharmaceutiques ou cosmetiques pour application topique et/ou parenterale, leurs procedes de preparation, et leurs utilisations
JP2010528039A (ja) 2007-05-23 2010-08-19 アラーガン、インコーポレイテッド 被覆されたヒアルロン酸粒子
US20080293637A1 (en) 2007-05-23 2008-11-27 Allergan, Inc. Cross-linked collagen and uses thereof
WO2008157608A1 (en) 2007-06-18 2008-12-24 Cartlix, Inc. Composite scaffolds for tissue regeneration
WO2009005790A2 (en) 2007-06-29 2009-01-08 Carbylan Biosurgery, Inc. Sterile thiol-derivatized hyaluronic acid polymer compositions and uses thereof
WO2009017705A1 (en) 2007-07-27 2009-02-05 Galderma Laboratories L.P. Compounds, formulations, and methods for reducing skin wrinkles, creasing and sagging
US8198245B2 (en) 2007-07-27 2012-06-12 Humacyte, Inc. Compositions and methods for soft tissue augmentation
US20110077737A1 (en) 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US20120071437A1 (en) 2007-07-30 2012-03-22 Allergan, Inc. Tunable crosslinked polysaccharide compositions
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8455459B2 (en) 2007-08-02 2013-06-04 Medicis Pharmaceutical Corporation Method of applying an injectable filler
FR2920000B1 (fr) 2007-08-13 2010-01-29 Oreal Composition cosmetique ou pharmaceutique contenant de l'acide hyaluronique, et procede cosmetique pour diminuer les signes du vieilissement
CA2734577A1 (en) 2007-08-16 2009-02-26 Carnegie Mellon University Inflammation-regulating compositions and methods
KR100813224B1 (ko) 2007-08-24 2008-03-13 한양대학교 산학협력단 단백질 약물전달용 온도 가역성 코아세르베이트 조합 겔
FR2920968B1 (fr) 2007-09-14 2009-11-13 Oreal Procede cosmetique de traitement esthetique et/ou reparateur de la peau
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
US7910134B2 (en) * 2007-10-29 2011-03-22 Ayman Boutros Alloplastic injectable dermal filler and methods of use thereof
JP5035900B2 (ja) 2007-11-21 2012-09-26 株式会社アイ・エイチ・アイ マリンユナイテッド 温度分布履歴推定方法
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
FR2924615B1 (fr) 2007-12-07 2010-01-22 Vivacy Lab Hydrogel cohesif biodegradable.
US9161970B2 (en) * 2007-12-12 2015-10-20 Allergan, Inc. Dermal filler
EP2222270B1 (en) * 2007-12-26 2018-11-14 Mark A. Pinsky Collagen formulations for improved skin care
US20090291986A1 (en) 2008-05-22 2009-11-26 Apostolos Pappas Composition and method of treating facial skin defect
US20090297632A1 (en) 2008-06-02 2009-12-03 Waugh Jacob M Device, Methods and Compositions to Alter Light Interplay with Skin
WO2010003797A1 (en) 2008-07-09 2010-01-14 Novozymes Biopharma Dk A/S Hyaluronic acid for corneal wound healing
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
US20130102563A1 (en) * 2008-08-04 2013-04-25 Allergan, Inc. Dermal filler with lidocaine
ES2658609T3 (es) 2008-09-02 2018-03-12 Tautona Group Lp Hilos de ácido hialurónico y/o derivados de los mismos, métodos para fabricar los mismos, y usos de los mismos
WO2010027471A2 (en) 2008-09-04 2010-03-11 The General Hospital Corporation Hydrogels for vocal cord and soft tissue augmentation and repair
GB0816496D0 (en) 2008-09-10 2008-10-15 Zhao Xiaobin Hyaluronic acid cryogel
JP5683957B2 (ja) 2008-09-30 2015-03-11 電気化学工業株式会社 光安定化された医薬組成物
US20100098794A1 (en) 2008-10-17 2010-04-22 Armand Gerard Topical anti-wrinkle and anti-aging moisturizing cream
US20100111919A1 (en) 2008-10-31 2010-05-06 Tyco Healthcare Group Lp Delayed gelation compositions and methods of use
WO2010053918A1 (en) 2008-11-05 2010-05-14 Hancock Jaffe Laboratories, Inc. Composite containing collagen and elastin as a dermal expander and tissue filler
SI2352488T1 (sl) 2008-11-07 2017-07-31 Klox Technologies Inc. Oksidativni fotoaktiviran sestavek za pomlajevanje kože, ki vsebuje hialuronsko kislino, glukozamin ali alantoin
FR2938187B1 (fr) 2008-11-07 2012-08-17 Anteis Sa Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur
ITRM20080636A1 (it) 2008-11-28 2010-05-29 Univ Palermo Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.
WO2010065784A2 (en) * 2008-12-03 2010-06-10 Jakk Group, Inc. Methods, devices, and compositions for dermal filling
SE533818C2 (sv) 2009-02-04 2011-01-25 Roxtec Ab Excentrisk del av en rör- eller kabelgenomföring
EP2236523B1 (en) 2009-03-30 2018-02-21 Scivision Biotech Inc. Method for producing cross-linked hyaluronic acid
AU2010232547A1 (en) 2009-04-02 2011-10-27 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
US9371402B2 (en) 2009-04-09 2016-06-21 Scivision Biotech Inc. Method for producing cross-linked hyaluronic acid
WO2010136585A2 (en) 2009-05-29 2010-12-02 Galderma Research & Development Combination of adrenergic receptor agonist -1 or -2, preferably brimonidine with fillers, preferablyhyaluronic acid
IT1395392B1 (it) 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
US8657795B2 (en) 2009-12-30 2014-02-25 Cook Medical Technologies Llc Vascular port
US20110171311A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171286A1 (en) 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
DE102010009460A1 (de) 2010-02-26 2011-09-01 Siemens Aktiengesellschaft Verfahren zur Übermittlung mehrerer medizinischer Bilddatensätze und System zur Verwaltung von Bilddatensätzen
KR101764451B1 (ko) 2010-03-12 2017-08-02 알러간 인더스트리 에스에이에스 피부 상태 개선을 위한 히알루론안 폴리머 및 만니톨을 포함하는 유체 조성물
EP3078388B1 (en) 2010-03-22 2019-02-20 Allergan, Inc. Cross-linked hydrogels for soft tissue augmentation
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
EP2979709B1 (en) 2010-10-20 2017-08-02 Allergan Holdings France S.A.S. Threads of cross-linked hyaluronic acid and use thereof
US9299476B2 (en) 2010-10-22 2016-03-29 Newsouth Innovations Pty Limited Polymeric material
FR2968306B1 (fr) 2010-12-06 2014-02-28 Teoxane Procede de preparation d'un gel reticule
FR2968305B1 (fr) 2010-12-06 2014-02-28 Teoxane Procede de preparation d'un gel reticule
US20120142628A1 (en) * 2010-12-07 2012-06-07 Allergan, Inc. Methods for treating crepitus
US8793408B2 (en) 2010-12-21 2014-07-29 Nikon Corporation Electronic device and program
BR112013021477A2 (pt) 2011-02-22 2016-10-11 Merz Pharma Gmbh & Co Kgaa método para a preparação in situ de um material de enchimento, biopolímero polianiônico e kit
KR102238406B1 (ko) 2011-06-03 2021-04-08 알러간 인더스트리 에스에이에스 항산화제를 포함하는 피부 충전제 조성물
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US20130116190A1 (en) 2011-09-06 2013-05-09 Allergan, Inc. Hyaluronic acid-collagen matrices for tissue engineering
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US20130116411A1 (en) 2011-09-06 2013-05-09 Allergan, Inc. Methods of making hyaluronic acid/collagen compositions
US20140011980A1 (en) 2012-07-03 2014-01-09 Allergan, Inc. Methods for sterilizing compositions and resulting compositions
US9627808B2 (en) 2015-04-13 2017-04-18 Tyco Electronics Brasil Ltda One piece connector with integral latching members

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