EP2019647A4 - Novel hydrophilic polymers as medical lubricants and gels - Google Patents

Novel hydrophilic polymers as medical lubricants and gels

Info

Publication number
EP2019647A4
EP2019647A4 EP07777140A EP07777140A EP2019647A4 EP 2019647 A4 EP2019647 A4 EP 2019647A4 EP 07777140 A EP07777140 A EP 07777140A EP 07777140 A EP07777140 A EP 07777140A EP 2019647 A4 EP2019647 A4 EP 2019647A4
Authority
EP
European Patent Office
Prior art keywords
gels
hydrophilic polymers
novel hydrophilic
medical lubricants
lubricants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07777140A
Other languages
German (de)
French (fr)
Other versions
EP2019647A2 (en
Inventor
Mark W Grinstaff
Michel Wathier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston University
Original Assignee
Boston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston University filed Critical Boston University
Priority to EP12174827A priority Critical patent/EP2543340A1/en
Publication of EP2019647A2 publication Critical patent/EP2019647A2/en
Publication of EP2019647A4 publication Critical patent/EP2019647A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/02—Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
    • C08G61/04—Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes only aliphatic carbon atoms
    • C08G61/06—Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes only aliphatic carbon atoms prepared by ring-opening of carbocyclic compounds
    • C08G61/08—Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes only aliphatic carbon atoms prepared by ring-opening of carbocyclic compounds of carbocyclic compounds containing one or more carbon-to-carbon double bonds in the ring
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/12—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule
    • C08G61/122—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides
    • C08G61/123—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds
    • C08G61/125—Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule derived from five- or six-membered heterocyclic compounds, other than imides derived from five-membered heterocyclic compounds with a five-membered ring containing one oxygen atom in the ring
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/14—Side-groups
    • C08G2261/142—Side-chains containing oxygen
    • C08G2261/1426—Side-chains containing oxygen containing carboxy groups (COOH) and/or -C(=O)O-moieties
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/30—Monomer units or repeat units incorporating structural elements in the main chain
    • C08G2261/33—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain
    • C08G2261/332—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain containing only carbon atoms
    • C08G2261/3324—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain containing only carbon atoms derived from norbornene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/30—Monomer units or repeat units incorporating structural elements in the main chain
    • C08G2261/33—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain
    • C08G2261/334—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain containing heteroatoms
    • C08G2261/3342—Monomer units or repeat units incorporating structural elements in the main chain incorporating non-aromatic structural elements in the main chain containing heteroatoms derived from cycloolefins containing heteroatoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L65/00—Compositions of macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain; Compositions of derivatives of such polymers
EP07777140A 2006-05-19 2007-05-18 Novel hydrophilic polymers as medical lubricants and gels Withdrawn EP2019647A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP12174827A EP2543340A1 (en) 2006-05-19 2007-05-18 Novel hydrophilic polymers as medical lubricants and gels

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80175106P 2006-05-19 2006-05-19
PCT/US2007/011888 WO2007136738A2 (en) 2006-05-19 2007-05-18 Novel hydrophilic polymers as medical lubricants and gels

Publications (2)

Publication Number Publication Date
EP2019647A2 EP2019647A2 (en) 2009-02-04
EP2019647A4 true EP2019647A4 (en) 2010-04-28

Family

ID=38723849

Family Applications (2)

Application Number Title Priority Date Filing Date
EP12174827A Withdrawn EP2543340A1 (en) 2006-05-19 2007-05-18 Novel hydrophilic polymers as medical lubricants and gels
EP07777140A Withdrawn EP2019647A4 (en) 2006-05-19 2007-05-18 Novel hydrophilic polymers as medical lubricants and gels

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP12174827A Withdrawn EP2543340A1 (en) 2006-05-19 2007-05-18 Novel hydrophilic polymers as medical lubricants and gels

Country Status (4)

Country Link
US (1) US8378064B2 (en)
EP (2) EP2543340A1 (en)
JP (1) JP2009537549A (en)
WO (1) WO2007136738A2 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861734B1 (en) 2003-04-10 2006-04-14 Corneal Ind CROSSLINKING OF LOW AND HIGH MOLECULAR MASS POLYSACCHARIDES; PREPARATION OF INJECTABLE SINGLE PHASE HYDROGELS; POLYSACCHARIDES AND HYDROGELS OBTAINED
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
KR101577471B1 (en) 2007-11-16 2015-12-14 알러간, 인코포레이티드 Compositions and methods for treating purpura
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
JP5722217B2 (en) 2008-09-02 2015-05-20 アラーガン・ホールディングス・フランス・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｈｏｌｄｉｎｇｓ Ｆｒａｎｃｅ Ｓ．Ａ．Ｓ． Yarn of hyaluronic acid and / or its derivative, method for its preparation and use thereof
FR2945949B1 (en) * 2009-05-26 2011-05-13 Anteis Sa HYDROGEL INJECTION FOR GLYCEROL SUPPLEMENTATION IN SKIN OVER LONG TERM.
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
WO2011110894A2 (en) 2010-03-12 2011-09-15 Allergan Industrie Sas Fluid composition for improving skin conditions
HUE043344T2 (en) 2010-03-22 2019-08-28 Allergan Inc Cross-linked hydrogels for soft tissue augmentation
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
WO2012097078A2 (en) * 2011-01-14 2012-07-19 Flex Biomedical Viscosupplementary materials
US20130344023A1 (en) * 2011-01-24 2013-12-26 Flex-Biomedical Polymer-active agent conjugates
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9186377B2 (en) 2011-06-03 2015-11-17 Maguire Abbey, Llc Method, composition, and articles for improving joint lubrication
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
CA3133676A1 (en) 2011-06-03 2012-12-06 Allergan Industrie, Sas Dermal filler compositions including antioxidants
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
WO2013112381A2 (en) 2012-01-24 2013-08-01 Bvw Holding Ag New class of anti-adhesion hydrogels with healing aspects
US8962772B2 (en) 2013-06-26 2015-02-24 International Business Machines Corporation Antimicrobial surface modified silicone rubber and methods of preparation thereof
EP3071236A4 (en) 2013-11-20 2017-05-24 Trustees of Boston University Injectable tissue supplement
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20180318279A1 (en) * 2015-10-23 2018-11-08 Rush University Medical Center Topical compositions providing pain relief and methods of use thereof
EP3452127A1 (en) 2016-05-03 2019-03-13 Bvw Holding AG Multiphase gel
EP3510112A2 (en) * 2016-11-15 2019-07-17 Albert-Ludwigs-Universität Freiburg A simultaneously antimicrobial and protein-repellent polyzwitterion
CN108047075A (en) * 2017-12-20 2018-05-18 蓬莱星火化工有限公司 The synthetic method of (methyl) acrylamide propyl-dimethyl amine
CN109942796B (en) * 2019-03-19 2021-04-06 广东海洋大学 Polystyptic-like cyclic acid, preparation method, hemostatic and antibacterial pharmaceutical composition and application thereof
CN116284691B (en) * 2023-03-27 2023-11-17 天津大学 Ion type cycloolefin copolymer with high transparency and antibacterial property and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19716312A1 (en) * 1997-04-11 1998-10-15 Hoechst Ag Catalyst and use of the catalyst for the polymerization
US20020141967A1 (en) * 1999-09-14 2002-10-03 Tepha, Inc. Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation
WO2005097869A1 (en) * 2004-04-01 2005-10-20 Cardiome Pharma Corp. Polymers comprising ion channel modulating compounds and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA228695A (en) 1923-02-13 W. Racklyeft John Ironing machine
HU188311B (en) * 1982-03-04 1986-04-28 Szendrei,Kalman,Hu Process for producing biologically active polisaccharide concentrates and pharmaceutical compositions containing them as active agents
IT1219587B (en) * 1988-05-13 1990-05-18 Fidia Farmaceutici SELF-CROSS-LINKED CARBOXYLY POLYSACCHARIDES
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5827937A (en) * 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
CN1555387A (en) 2000-07-28 2004-12-15 古德里奇公司 Polymeric compositions for forming optical waveguides, optical waveguides formed therefrom, and methods for making same
JP2005521629A (en) * 2001-06-25 2005-07-21 デピユイ・インターナシヨナル・リミテツド Composition comprising glycosaminoglycan and hyaluronidase inhibitor for treating arthritic joints
US6872792B2 (en) * 2001-06-25 2005-03-29 Lord Corporation Metathesis polymerization adhesives and coatings
EP1531757B1 (en) * 2002-07-19 2016-09-07 Omeros Corporation Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from
KR100810770B1 (en) 2003-09-17 2008-03-07 일라이 릴리 앤드 캄파니 Synthetic Polysaccharide Antigens for Immunological Intervention in Disease
EP2754454A3 (en) 2004-01-07 2014-09-24 Seikagaku Corporation Non-steroidal anti-inflammatory drug derivatives
US9216224B2 (en) 2010-03-05 2015-12-22 Catabasis Pharmaceuticals, Inc. Fatty acid COX inhibitor derivatives and their uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19716312A1 (en) * 1997-04-11 1998-10-15 Hoechst Ag Catalyst and use of the catalyst for the polymerization
US20020141967A1 (en) * 1999-09-14 2002-10-03 Tepha, Inc. Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation
WO2005097869A1 (en) * 2004-04-01 2005-10-20 Cardiome Pharma Corp. Polymers comprising ion channel modulating compounds and uses thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BENEDICTO A D ET AL: "MICROSTRUCTURAL STUDIES OF POLY(7-OXABICYCLO(2.2.1)HEPT-2-ENE) DERIVATIVES PREPARED FROM SELECTED RUTHENIUM CATALYSTS", MACROMOLECULES, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC; US, vol. 25, no. 22, 26 October 1992 (1992-10-26), pages 5893 - 5900, XP000315444, ISSN: 0024-9297, DOI: 10.1021/MA00048A006 *
CRAYMER JEANETTE F ET AL: "Emulsion polymerization of functionalized norbornenes and oxanorbornenes", POLYMER PREPRINTS, AMERICAN CHEMICAL SOCIETY, US, vol. 46, no. 2, 1 January 2005 (2005-01-01), pages 884 - 885, XP009130745, ISSN: 0032-3934 *
LADMIRAL V ET AL: "Synthetic glycopolymers: an overview", EUROPEAN POLYMER JOURNAL, PERGAMON PRESS LTD. OXFORD, GB, vol. 40, no. 3, 1 March 2004 (2004-03-01), pages 431 - 449, XP004488663, ISSN: 0014-3057 *
NOMURA K ET AL: "PREPARATION OF SUGAR-COATED HOMOPOLYMERS AND MULTIBLOCK ROMP COPOLYMERS", MACROMOLECULES, ACS, WASHINGTON, DC, US, vol. 29, no. 2, 15 January 1996 (1996-01-15), pages 540 - 545, XP000545165, ISSN: 0024-9297 *
STEFAN MEIER: "Neue cycloaliphatische Polymere und Polymerdispersionen durch übergangsmetallkatalysierte Polymerisation cyclischer Olefine und polymeranaloge Reaktionen", DISSERTATION, 2 June 2003 (2003-06-02), pages 89 - 140, XP002573296, Retrieved from the Internet <URL:http://www.freidok.uni-freiburg.de/volltexte/706/pdf/Diss_Meier_Freidok.pdf> [retrieved on 20100316] *
WALSH ELISABETH B ET AL: "Synthesis of novel hydrophilic biopolymers", ABSTRACTS OF PAPERS. ACS NATIONAL MEETING, XX, XX, vol. 220th, 20 August 2000 (2000-08-20), pages POLY - 319, XP009106943 *

Also Published As

Publication number Publication date
US8378064B2 (en) 2013-02-19
EP2543340A1 (en) 2013-01-09
WO2007136738A3 (en) 2008-03-13
JP2009537549A (en) 2009-10-29
WO2007136738A2 (en) 2007-11-29
EP2019647A2 (en) 2009-02-04
US20090208589A1 (en) 2009-08-20

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