SG10202104803SA - Hyaluronic Acid-Based Gels Including Anesthetic Agents - Google Patents

Hyaluronic Acid-Based Gels Including Anesthetic Agents

Info

Publication number
SG10202104803SA
SG10202104803SA SG10202104803SA SG10202104803SA SG10202104803SA SG 10202104803S A SG10202104803S A SG 10202104803SA SG 10202104803S A SG10202104803S A SG 10202104803SA SG 10202104803S A SG10202104803S A SG 10202104803SA SG 10202104803S A SG10202104803S A SG 10202104803SA
Authority
SG
Singapore
Prior art keywords
hyaluronic acid
anesthetic agents
based gels
gels including
including anesthetic
Prior art date
Application number
SG10202104803SA
Inventor
Pierre Lebreton
Original Assignee
Allergan Ind Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41608613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10202104803S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Ind Sas filed Critical Allergan Ind Sas
Publication of SG10202104803SA publication Critical patent/SG10202104803SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/001Preparations for care of the lips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023Heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10202104803SA 2008-08-04 2009-03-02 Hyaluronic Acid-Based Gels Including Anesthetic Agents SG10202104803SA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8595608P 2008-08-04 2008-08-04
US8793408P 2008-08-11 2008-08-11
US9627808P 2008-09-11 2008-09-11
US12/393,768 US8450475B2 (en) 2008-08-04 2009-02-26 Hyaluronic acid-based gels including lidocaine
US12/393,884 US8357795B2 (en) 2008-08-04 2009-02-26 Hyaluronic acid-based gels including lidocaine

Publications (1)

Publication Number Publication Date
SG10202104803SA true SG10202104803SA (en) 2021-06-29

Family

ID=41608613

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201505441TA SG10201505441TA (en) 2008-08-04 2009-03-02 Hyaluronic Acid-Based Gels Including Anesthetic Agents
SG10202104803SA SG10202104803SA (en) 2008-08-04 2009-03-02 Hyaluronic Acid-Based Gels Including Anesthetic Agents

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201505441TA SG10201505441TA (en) 2008-08-04 2009-03-02 Hyaluronic Acid-Based Gels Including Anesthetic Agents

Country Status (20)

Country Link
US (22) US8450475B2 (en)
EP (6) EP3205332A1 (en)
JP (5) JP5670899B2 (en)
KR (2) KR101672562B1 (en)
CN (3) CN102170855B (en)
AU (2) AU2009278883B2 (en)
BR (3) BRPI0917573B1 (en)
CA (6) CA3112106C (en)
CY (2) CY1118281T1 (en)
DK (3) DK2326302T3 (en)
ES (3) ES2622708T3 (en)
HK (2) HK1156883A1 (en)
HU (3) HUE031483T2 (en)
MX (3) MX2011001322A (en)
PL (3) PL2674147T3 (en)
PT (2) PT2326302T (en)
RU (2) RU2496473C2 (en)
SG (2) SG10201505441TA (en)
SI (2) SI2323617T1 (en)
WO (2) WO2010015901A1 (en)

Families Citing this family (153)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861734B1 (en) 2003-04-10 2006-04-14 Corneal Ind CROSSLINKING OF LOW AND HIGH MOLECULAR MASS POLYSACCHARIDES; PREPARATION OF INJECTABLE SINGLE PHASE HYDROGELS; POLYSACCHARIDES AND HYDROGELS OBTAINED
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US20080293637A1 (en) * 2007-05-23 2008-11-27 Allergan, Inc. Cross-linked collagen and uses thereof
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US20120071437A1 (en) 2007-07-30 2012-03-22 Allergan, Inc. Tunable crosslinked polysaccharide compositions
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
BRPI0819075A2 (en) 2007-11-16 2014-10-07 Vicept Therapeutics Inc METHOD FOR TREATING PURPOSE IN AN INDIVIDUAL AND METHOD FOR REDUCING PURPOSE IN AN INDIVIDUAL BEFORE SURGICAL PROCEDURE
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US20130102563A1 (en) * 2008-08-04 2013-04-25 Allergan, Inc. Dermal filler with lidocaine
US8450475B2 (en) * 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (en) 2008-09-02 2020-08-12 Tautona Group LP Threads of hyaluronic acid, methods of making thereof and uses thereof
AU2009322463B2 (en) 2008-12-02 2015-10-08 Allergan, Inc. Injection device
IT1395392B1 (en) * 2009-08-27 2012-09-14 Fidia Farmaceutici VISCOELASTIC FROSTS LIKE NEW FILLERS
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110171310A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use
AU2015234293B2 (en) * 2010-01-13 2017-04-27 Allergan Industrie Sas Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
NZ602405A (en) 2010-03-12 2014-12-24 Allergan Ind Sas A fluid composition comprising a hyaluronan polymer and mannitol for improving skin conditions
AU2011229730B2 (en) 2010-03-22 2016-01-07 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
WO2012008722A2 (en) * 2010-07-12 2012-01-19 신풍제약 주식회사 Filler composition for tissue reinforcement
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
PL3138586T3 (en) * 2010-11-08 2021-09-13 Allergan Industrie, Sas Soft tissue filler
PT2637710T (en) * 2010-11-08 2017-07-12 Allergan Ind Sas Hyaluronic acid based formulations
FR2968305B1 (en) 2010-12-06 2014-02-28 Teoxane PROCESS FOR PREPARING RETICULATED GEL
EA201391014A1 (en) * 2011-01-06 2014-01-30 С. Лоуэлл Парсонс METHOD OF MANUFACTURING COMPOSITIONS CONTAINING LOCAL ANESTHETIC, HEPARINOID AND BUFFER
EP2663342B1 (en) * 2011-01-13 2020-03-25 Allergan, Inc. Stable hydrogel compositions including phenylephrine
EP2484387A1 (en) * 2011-02-03 2012-08-08 Q-Med AB Hyaluronic acid composition
KR102073027B1 (en) * 2011-04-05 2020-02-04 삼성전자 주식회사 Method and appratus of operating multiple time alignment timer in mobile communication system using carrier aggregation
CA2827615A1 (en) 2011-02-17 2012-08-23 Dennis E. Van Epps Compositions and improved soft tissue replacement methods
EP2606828B1 (en) * 2011-12-20 2018-04-11 Angioclinic AG Hyaluronic acid and its use for treating venous insufficiency and varicose veins
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
EP3536307B1 (en) 2011-06-03 2021-10-20 ALLERGAN Industrie, SAS Dermal filler compositions including antioxidants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
LT2742070T (en) * 2011-08-10 2021-10-25 Glycores 2000 Srl Degradation-resistant cross-linked, low-molecular-weight hyaluronate
DK2747747T3 (en) 2011-08-25 2020-03-09 Allergan Ind Sas DERMAL FILLING COMPOSITIONS INCLUDING ANTIOXIDANTS
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
RU2626513C2 (en) 2011-09-14 2017-07-28 Аллерган, Инк. Dermal filler composition for small wrinkles treating
EP2581079B1 (en) * 2011-10-11 2016-12-07 BioPolymer GmbH & Co. KG Combination of hyaluronic acid and prilocaine
EP3243533B1 (en) * 2011-10-11 2020-06-17 Allergan Holdings France S.A.S. Threads of cross-linked hyaluronic acid and methods of use thereof
ES2824232T3 (en) 2011-12-08 2021-05-11 Allergan Ind Sas Dermal filler compositions
CN102552974A (en) * 2012-02-17 2012-07-11 上海白衣缘生物工程有限公司 Gel composition for injection filling of skins and preparation method for gel composition
LT2861626T (en) * 2012-06-15 2019-01-25 Merz Pharma Gmbh & Co. Kgaa Method of preparing a composition based on hyaluronic acid
ES2660023T3 (en) * 2012-07-18 2018-03-20 Allergan Industrie, Sas Hyaluronic acid formulation containing pyruvate
CH705713B1 (en) * 2012-09-21 2013-05-15 Labo Cosprophar Ag Dermocosmetic composition with filling action, useful e.g. for smoothing wrinkles or furrows in epidermis by topical application, comprises mixture containing hyaluronic acids, which includes e.g. hyaluronic acid crosspolymer, and carrier
EP2903588B1 (en) 2012-10-02 2020-02-19 Allergan, Inc. Dermal filler hydrogels with vitamin a/cyclodextrin inclusion complexes
WO2014055895A1 (en) 2012-10-05 2014-04-10 Allergan, Inc. Injectable device and method for sculpting, augmenting or correcting facial features such as the chin
US20140124514A1 (en) * 2012-11-08 2014-05-08 Onpharma, Inc. Method and apparatus for adding buffers and other substances to medical cartridges
BR112015017040B1 (en) 2013-01-17 2020-11-03 Jeffrey Hagel use of hyaluronic acid to increase muscle muscle volume and alter muscle contour in a human
CN105263503A (en) * 2013-01-28 2016-01-20 奥利金制药公司 Stable compositions comprising heparinoid, acute-acting anesthetic, and buffer
BR112015021933B1 (en) 2013-03-08 2020-12-08 Ultradent Products, Inc oral treatment device, tooth whitening device and method of making an oral treatment device
FR3006689A1 (en) * 2013-06-11 2014-12-12 Benedicte Vincente Tauzin PROCESS FOR CROSSLINKING HYALURONIC ACID; PROCESS FOR PREPARING AN INJECTABLE HYDROGEL; HYDROGEL OBTAINED; USE OF HYDROGET OBTAINED
CN104225677B (en) * 2013-06-13 2016-09-21 山东省生物药物研究院 Cross-linked-hyaluronic acid cell scaffold material and its preparation method and application
BR112015031329A2 (en) * 2013-06-14 2017-07-25 Galderma Sa compositions comprising cyclodextrin and cross-linked hyaluronic acid
KR20160029818A (en) * 2013-07-08 2016-03-15 덴카 주식회사 Core-shell crosslinked hyaluronic acid gel particles, production method for same, and medical material
US9421198B2 (en) 2013-07-30 2016-08-23 Teoxane Composition comprising hyaluronic acid and mepivacaine
CA2923742C (en) * 2013-09-27 2021-02-16 Anteis S.A. Method for obtaining an injectable hydrogel based on hyaluronic acid containing lidocaine added in powder form, and an alkaline agent, sterilized with heat
EP3052529B1 (en) 2013-09-30 2017-10-04 Galderma S.A. Single-step functionalization and cross-linking of hyaluronic acid
US10913853B2 (en) 2013-10-11 2021-02-09 Ultradent Products, Inc. Wax-based compositions, articles made therefrom, and methods of manufacture and use
KR102133526B1 (en) * 2013-10-31 2020-07-13 삼성전자주식회사 Scheme for supporting wireless transmission using usb application data qos
US20150141910A1 (en) * 2013-11-14 2015-05-21 University Medical Pharmaceuticals Corporation Microneedles for therapeutic agent delivery with improved mechanical properties
FR3015290B1 (en) * 2013-12-23 2017-01-13 Lab Vivacy HYALURONIC ACID COMPOSITIONS COMPRISING MEPIVACAINE
WO2015112907A1 (en) * 2014-01-27 2015-07-30 Allergan Holdings France S.A.S. Spherical forms of cross-linked hyaluronic acid and methods of use thereof
AR099900A1 (en) 2014-04-01 2016-08-24 Merz Pharma Gmbh & Co Kgaa FILLINGS FOR SOFT FABRICS WITH POLYSACARIDS WITH IMPROVED PERSISTENCE, KIT, PROCEDURE, USE
WO2015149177A1 (en) 2014-04-01 2015-10-08 Klox Technologies Inc. Tissue filler compositions and methods of use
EP3126008B1 (en) * 2014-04-02 2020-08-05 Merz Pharma GmbH & Co. KGaA In vivo degradation of polysaccharide-containing fillers
WO2015164533A1 (en) * 2014-04-22 2015-10-29 Allergan, Inc. Dry dermal filler compositions and methods of reconstitution
EP3200838B1 (en) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stable hydrogel compositions including additives
US20180265652A1 (en) * 2014-10-08 2018-09-20 Therakine Biodelivery Gmbh Cross-linked biopolymer macroscopic systems and method of making same
WO2016057607A1 (en) * 2014-10-08 2016-04-14 Therakine Micronized hydrophilic cross-linked biopolymer systems and method of making same
TWI716365B (en) * 2014-11-13 2021-01-21 德商梅茲製藥有限兩合公司 Injectable dermal filler composition, a kit comprising the same, a method for preparing the same, and a use thereof
JP6946187B2 (en) 2014-12-02 2021-10-06 エボルブド バイ ネイチャー, インコーポレイテッド Silk performance garments and products, and how to manufacture them
FR3029928B1 (en) 2014-12-15 2018-03-09 Teoxane RETICULATED GEL
WO2016115532A1 (en) * 2015-01-16 2016-07-21 Spineovations, Inc. Method of treating spinal disk
CN105878051B (en) * 2015-01-26 2019-02-26 华熙福瑞达生物医药有限公司 Honeycomb hyaluronic acid and preparation method thereof
CN107427584A (en) 2015-01-28 2017-12-01 阿勒根公司 Joint fat pad preparation and its application method
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
WO2016129967A1 (en) * 2015-02-13 2016-08-18 주식회사 엔도더마 Microstructure using cross-linked hyaluronic acid hydrogel, and method for producing same
WO2016132167A1 (en) * 2015-02-16 2016-08-25 Allergan Industrie, Sas Implants for sculpting, augmenting or correcting facial features such as the chin
PL3256179T3 (en) * 2015-02-13 2020-05-18 Allergan Industrie, Sas Implants for sculpting, augmenting or correcting facial features such as the chin
US10004824B2 (en) 2015-05-11 2018-06-26 Laboratoires Vivacy Compositions comprising at least one polyol and at least one anesthetic
FR3036035B1 (en) 2015-05-11 2018-10-05 Laboratoires Vivacy COMPOSITIONS COMPRISING AT LEAST ONE POLYOL AND AT LEAST ONE ANESTHETIC
FR3037797B1 (en) 2015-06-24 2018-08-17 Kylane Laboratoires Sa PROCESS FOR THE PREPARATION OF AN INJECTABLE RETICULATED HYDROGEL HYDROGEL OBTAINED; USE OF HYDROGEL OBTAINED
WO2017001056A1 (en) * 2015-06-30 2017-01-05 Merz Pharma Gmbh & Co. Kgaa Method for producing crosslinked hyaluronic acid
ES2836473T3 (en) 2015-06-30 2021-06-25 Merz Pharma Gmbh & Co Kgaa Method of preparing a composition based on hyaluronic acid
CN108135975A (en) 2015-07-14 2018-06-08 丝绸医疗公司 Silk performance clothes and product and preparation method thereof
EP3328351A1 (en) 2015-07-27 2018-06-06 Galderma S.A. A process for efficient cross-linking of hyaluronic acid
CN105107018B (en) * 2015-08-19 2018-08-24 李媚 A kind of preparation method of sterile injection material
CN105131348B (en) * 2015-08-19 2018-01-16 李媚 A kind of sterile injectable material
KR101720426B1 (en) 2015-09-01 2017-04-14 (주)시지바이오 Composition comprising hyaluronic acid and the method for preparing the same
EP3162813A1 (en) * 2015-11-02 2017-05-03 Merz Pharma GmbH & Co. KGaA Process for depleting epoxide species in crosslinked poly-saccharide gel compositions and compositions obtained thereby
BR112018009337A8 (en) 2015-11-10 2019-02-26 E Perito Paul system and method for non-surgical increase of penile circumference
RU2697671C1 (en) * 2015-11-24 2019-08-16 БиЭмАй КОРЕЯ КО., ЛТД Composition for injections of hyaluronic acid containing hyaluronic acid derivative and dna fraction, and use thereof
FR3044557B1 (en) 2015-12-07 2017-12-01 Benedicte Vincente Gavard Molliard Tauzin NOVEL COMPOSITION INJECTABLE; PROCESS FOR THE PREPARATION OF SAID COMPOSITION; USE OF SAID COMPOSITION
KR102139337B1 (en) 2016-03-17 2020-07-29 주식회사 엘지생활건강 Soluble microneedle patch containing hyaluronic acid dermal filler
TWI727014B (en) * 2016-03-24 2021-05-11 德商梅茲製藥有限兩合公司 Modified hyaluronic acid, method for making same and uses thereof
KR101660211B1 (en) * 2016-06-07 2016-09-26 동국제약 주식회사 Crosslinked hyalruonic acid gel having monophasic and biphasic characteristics, preparation method thereof and use thereof
EP3895742A1 (en) 2016-10-13 2021-10-20 Allergan, Inc. Coacervate hyaluronan hydrogels for dermal filler applications
FR3058064B1 (en) 2016-10-28 2020-08-07 Lab Vivacy COMPOSITION BASED ON HYALURONIC ACID INCLUDING MEPIVACAINE
US11382853B2 (en) * 2016-11-11 2022-07-12 Anteis S.A. Hyaluronic acid dermal fillers crosslinked with citric acid, method for making same and uses thereof
KR101879065B1 (en) * 2016-12-12 2018-07-17 구태훈 Filler for soft tissue having particles of bead type and, manufacturing methods for the same
KR101922711B1 (en) * 2016-12-28 2018-11-27 주식회사 유영제약 A method for purification of cross-linked hyaluronic acid gel
KR102363007B1 (en) * 2017-01-18 2022-02-14 구태훈 HA filler having the properties of mono-phasic HA filler and bi-phasic HA filler, syringe used for the HA filler and, manufacturing methods for the HA filler
CN110573190B (en) * 2017-02-28 2022-01-25 Cg生物技术有限公司 Composition for skin injection
AU2018228301B2 (en) 2017-02-28 2020-12-17 Cg Bio Co., Ltd. Composition For Dermal Injection
BR112019017795B1 (en) 2017-02-28 2022-12-06 Cg Bio Co., Ltd. COMPOSITION FOR DERMAL INJECTION
AU2018240375C1 (en) 2017-03-22 2024-02-01 Ascendis Pharma A/S Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
KR101917026B1 (en) 2017-03-24 2019-01-24 박원진 Cosmetic composition for skin wrinkle improvement and prevention
EP3609483A4 (en) * 2017-04-12 2021-01-20 Urigen Pharmaceuticals, Inc. Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability
SG11201913229PA (en) * 2017-06-26 2020-01-30 Evolved By Nature Inc Silk-hyaluronic acid based tissue fillers and methods of using the same
US20230190997A1 (en) * 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
CN111712514A (en) 2017-09-27 2020-09-25 自然进化公司 Silk coated fabrics and products and methods of making same
ES2960617T3 (en) 2017-10-19 2024-03-05 Lifecell Corp Fluid Acellular Tissue Matrix Products and Production Methods
KR102091452B1 (en) * 2017-12-19 2020-03-20 대화제약 주식회사 Method for preparing prefilled syringe comprising local anesthetics and hyaluronic acid hydrogel
CN111918639A (en) * 2017-12-29 2020-11-10 马特克斯拉比有限公司 Method for preparing filling having hyaluronic acid group using specific cross-linking agent
PL3731808T3 (en) * 2017-12-29 2024-03-18 Matex Lab S.P.A. Method to prepare filler with a hyaluronic acid base comprising a neutralization step
US11534384B2 (en) * 2017-12-29 2022-12-27 Matex Lab S.P.A. Method to prepare a filler with hyaluronic acid base comprising a neutralization step
IT201800001890A1 (en) * 2018-01-25 2019-07-25 Fidia Farm Spa PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF POSTOPERATIVE PAIN
JP2021522926A (en) 2018-05-09 2021-09-02 ザ ジョンズ ホプキンス ユニバーシティ Nanofiber-hydrogel complex for soft tissue filling and enhanced regeneration
AU2019267711A1 (en) 2018-05-09 2020-12-03 The Johns Hopkins University Nanofiber-hydrogel composites for cell and tissue delivery
CN108653817B (en) * 2018-05-24 2021-02-02 上海其胜生物制剂有限公司 Preparation method of novel collagen stimulant
KR102392812B1 (en) * 2018-07-06 2022-04-29 주식회사 엘지화학 Hyaluronic acid filler having both of high viscoelasticity and cohesivity
AU2019302833B2 (en) * 2018-07-10 2022-09-22 Lg Chem, Ltd. Hyaluronic acid filler having high lift capacity and low injection force
WO2020030629A1 (en) 2018-08-07 2020-02-13 Merz Pharma Gmbh & Co. Kgaa Method for dynamic filtration of a cross-linked hydrogel
KR20200046649A (en) 2018-10-25 2020-05-07 (주)뉴크레이티브랩 The method of Producing Hyaluronic Acid Mixed with Mono and Biphasic
CA3122116C (en) * 2018-12-20 2023-07-18 Lg Chem, Ltd. Filler having excellent filler properties comprising hyaluronic acid hydrogel
BR112021012059A2 (en) * 2018-12-21 2021-10-19 Lg Chem, Ltd. FILLER INCLUDING HYALURONIC ACID HYDROGEL WITH EXCELLENT FILLING PROPERTIES
EP3946246A4 (en) * 2019-03-24 2023-06-21 Allergan Pharmaceuticals International Limited Injectable homogeneous gels comprising multiple forms of hyaluronic acid and methods for manufacturing thereof
US20220202793A1 (en) * 2019-05-17 2022-06-30 The Governing Council Of The University Of Toronto Sustained release local anesthetic hydrogel composition
WO2021132969A1 (en) * 2019-12-24 2021-07-01 주식회사 엘지화학 Injectable composition comprising anesthetic, buffer solution and hyaluronic acid hydrogel, and preparation method therefor
US11058640B1 (en) 2020-04-07 2021-07-13 Amc Group, Llc Hyaluronate compositions and soft tissue fillers
FR3109153B1 (en) * 2020-04-10 2022-07-15 Teoxane SA Compositions based on at least two glycosaminoglycans
US20230172968A1 (en) * 2020-04-17 2023-06-08 Prohibix Llc Controlled release hyaluronic acid compositions
KR102417671B1 (en) * 2020-04-28 2022-07-06 충남대학교산학협력단 Hyaluronic acid-based filler composition having self-crosslinking system and method for manufacturing the same
KR102425496B1 (en) 2020-05-08 2022-07-26 주식회사 종근당 Crosslinked hyaluronic acid having high elasticity, high viscosity and high effective cross-linker ratio, and preparing method thereof
FR3111903B1 (en) 2020-06-24 2022-12-02 Lab Vivacy METHOD FOR INCORPORATING ORGANIC COMPOUNDS IN SOLUTION WITHIN A HYDROGEL
CN111643730A (en) * 2020-07-14 2020-09-11 华熙生物科技股份有限公司 Preparation method and application of crosslinked hyaluronic acid gel for injection
WO2023080886A1 (en) * 2020-09-29 2023-05-11 Ziropa, Inc. Compositions and methods for pain relief and numbing
TR202101065A1 (en) * 2021-01-25 2022-08-22 Hacettepe Ueniversitesi A TISSUE FILLING MATERIAL CONTAINING HYALURONIC ACID GEL AND PRODUCTION METHOD
KR102581434B1 (en) * 2021-02-09 2023-09-22 (주)제테마 Solution used for production of composition of hyaluronic acid filler and composition of hyaluronic acid filler using the same
CN113449476B (en) * 2021-07-08 2022-07-05 浙江大学 Stacking-based soft measurement method for butane content in debutanizer
KR102348467B1 (en) * 2021-07-14 2022-01-07 주식회사 휴메딕스 A method for manufacturing a filler containing dna fraction and the filler prepared therefrom
KR102640893B1 (en) * 2021-11-12 2024-02-27 주식회사 유영제약 Method for preparing composition comprising crosslinked hyaluronic acids
CN116212108B (en) * 2023-04-18 2023-10-20 杭州科腾生物制品有限公司 Double-layer crosslinked gel containing lidocaine and preparation method and application thereof

Family Cites Families (270)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2128827A (en) 1938-03-09 1938-08-30 Frank B Killian Method and apparatus for manufacturing thin rubber articles
CA807629A (en) 1966-06-30 1969-03-04 Eigen Edward Lotion and detergent compositions
JPS4838158B1 (en) 1970-10-05 1973-11-15
CA949965A (en) 1971-12-03 1974-06-25 Robert H. Marchessault Method of preparing cross-linked starch and starch derivatives
US3769009A (en) * 1971-12-29 1973-10-30 Xerox Corp Inking system for liquid particle migration on automatic machines
US3949073A (en) 1974-11-18 1976-04-06 The Board Of Trustees Of Leland Stanford Junior University Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
US4233360A (en) 1975-10-22 1980-11-11 Collagen Corporation Non-antigenic collagen and articles of manufacture
CA1073360A (en) 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
JPS581933Y2 (en) 1979-04-23 1983-01-13 株式会社日本製鋼所 Cable clamp device
JPS55153711A (en) 1979-05-19 1980-11-29 Pola Chem Ind Inc Cosmetic lotion
US4279812A (en) 1979-09-12 1981-07-21 Seton Company Process for preparing macromolecular biologically active collagen
JPS6052129B2 (en) 1979-10-04 1985-11-18 呉羽化学工業株式会社 Manufacturing method of medical collagen fiber
US4424208A (en) 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
US4501306A (en) 1982-11-09 1985-02-26 Collagen Corporation Automatic syringe filling system
SE442820B (en) 1984-06-08 1986-02-03 Pharmacia Ab GEL OF THE CROSS-BOND HYALURONIC ACID FOR USE AS A GLASS BODY SUBSTITUTE
SE456346B (en) 1984-07-23 1988-09-26 Pharmacia Ab GEL TO PREVENT ADHESION BETWEEN BODY TISSUE AND SET FOR ITS PREPARATION
US4582865A (en) 1984-12-06 1986-04-15 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4636524A (en) 1984-12-06 1987-01-13 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
US4605691A (en) 1984-12-06 1986-08-12 Biomatrix, Inc. Cross-linked gels of hyaluronic acid and products containing such gels
SE8501022L (en) 1985-03-01 1986-09-02 Pharmacia Ab FORMAT CREATES AND PROCEDURES FOR ITS PREPARATION
US4713448A (en) 1985-03-12 1987-12-15 Biomatrix, Inc. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
SE452469B (en) 1986-06-18 1987-11-30 Pharmacia Ab MATERIALS CONSISTING OF A CROSS-BONDED CARBOXYL-GROUPED POLYSACCHARIDE AND PROCEDURE IN THE PREPARATION OF THE SAME
US4803075A (en) 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
FR2608456B1 (en) 1986-12-18 1993-06-18 Mero Rousselot Satia MICROCAPSULES BASED ON GELATIN AND POLYSACCHARIDES AND PROCESS FOR OBTAINING THEM
US5385938B1 (en) 1986-12-23 1997-07-15 Tristrata Inc Method of using glycolic acid for treating wrinkles
US5091171B2 (en) 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US5079236A (en) 1987-05-27 1992-01-07 Hyal Pharmaceutical Corporation Pure, sterile, pyrogen-free hyaluronic acid formulations their methods of preparation and methods of use
FR2623167B2 (en) 1987-08-14 1992-08-07 Genus Int IMPROVEMENT IN ARTICLES WITH ELASTIC ARTICULATIONS RIGIDIFYING ON THEIR TENSIONING
US5017229A (en) 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
IT1219587B (en) 1988-05-13 1990-05-18 Fidia Farmaceutici SELF-CROSS-LINKED CARBOXYLY POLYSACCHARIDES
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5643464A (en) 1988-11-21 1997-07-01 Collagen Corporation Process for preparing a sterile, dry crosslinking agent
US5614587A (en) 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
US5565519A (en) 1988-11-21 1996-10-15 Collagen Corporation Clear, chemically modified collagen-synthetic polymer conjugates for ophthalmic applications
SE462587B (en) 1988-11-30 1990-07-23 Wiklund Henry & Co DEVICE FOR MARKING THE WORK PAPER WITH WRITTEN OR OTHER SIGNS
JPH02215707A (en) 1989-02-15 1990-08-28 Chisso Corp Skin cosmetic
ES2075148T3 (en) 1989-05-19 1995-10-01 Hayashibara Biochem Lab ALPHA-GLYCOSYL-L-ASCORBIC ACID, AND ITS PREPARATION AND USES.
EP0416250A3 (en) 1989-08-01 1991-08-28 The Research Foundation Of State University Of New York N-acylurea and o-acylisourea derivatives of hyaluronic acid
US5356883A (en) 1989-08-01 1994-10-18 Research Foundation Of State University Of N.Y. Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
CA2023922A1 (en) 1989-09-05 1991-03-06 James M. Curtis Method of manufacturing an implantable article provided with a micropillared surface
JP2832848B2 (en) 1989-10-21 1998-12-09 株式会社林原生物化学研究所 Crystal 2-O-α-D-glucopyranosyl-L-ascorbic acid, its production method and use
US4996787A (en) * 1990-05-29 1991-03-05 Jack N. Holcomb SigSauer pistol with concealed radio transmitter
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5246698A (en) 1990-07-09 1993-09-21 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
US5283671A (en) * 1991-02-20 1994-02-01 Stewart John R Method and apparatus for converting RGB digital data to optimized CMYK digital data
JP3115625B2 (en) 1991-03-30 2000-12-11 帝國製薬株式会社 Topical patch containing lidocaine
US5314874A (en) 1991-04-19 1994-05-24 Koken Co., Ltd. Intracorporeally injectable composition for implanting highly concentrated cross-linked atelocollagen
DE4200080A1 (en) 1992-01-03 1993-09-30 Reinmueller Johannes Pharmaceutical composition for wound, scar and keloid treatment
JP3267972B2 (en) 1992-02-28 2002-03-25 コラーゲン コーポレイション High concentration homogenized collagen composition
IT1260154B (en) 1992-07-03 1996-03-28 Lanfranco Callegaro HYALURONIC ACID AND ITS DERIVATIVES IN INTERPENETRATING POLYMERS (IPN)
WO1994017227A1 (en) 1993-01-20 1994-08-04 E.R. Squibb And Sons, Inc. Fibres
JP2995090B2 (en) 1993-03-19 1999-12-27 キユー・メド・アクチエボラーグ Compositions and methods for tissue augmentation
US5531716A (en) 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US5616568A (en) 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
CA2146090C (en) 1994-05-10 1998-11-24 Mark E. Mitchell Apparatus and method of mixing materials in a sterile environment
US5616689A (en) 1994-07-13 1997-04-01 Collagen Corporation Method of controlling structure stability of collagen fibers produced form solutions or dispersions treated with sodium hydroxide for infectious agent deactivation
AU706434B2 (en) 1994-10-18 1999-06-17 Ethicon Inc. Injectable liquid copolymers for soft tissue repair and augmentation
US20050186673A1 (en) 1995-02-22 2005-08-25 Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie Collagen carrier of therapeutic genetic material, and method
US5972326A (en) 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
US5612027A (en) 1995-04-18 1997-03-18 Galin; Miles A. Controlled release of miotic and mydriatic drugs in the anterior chamber
FR2733427B1 (en) 1995-04-25 2001-05-25 W K Et Associes INJECTABLE BIPHASIC COMPOSITIONS CONTAINING HYALURONIC ACID, ESPECIALLY USEFUL IN REPAIRING AND AESTHETIC SURGERIES
FR2733426B1 (en) 1995-04-25 1997-07-18 Debacker Yves MEDICAL DEVICE FOR FILLING SKIN VOLUME DEFORMATIONS SUCH AS WRINKLES AND SCARS BY INJECTION OF 2 DIFFERENT PHYSICO-CHEMICAL FORMS OF A BIOLOGICAL POLYMER
US6214331B1 (en) 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6284284B1 (en) 1995-06-06 2001-09-04 Advanced Tissue Sciences, Inc. Compositions and methods for production and use of an injectable naturally secreted extracellular matrix
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
US5571503A (en) 1995-08-01 1996-11-05 Mausner; Jack Anti-pollution cosmetic composition
US6007843A (en) 1995-09-29 1999-12-28 Lam Pharmaceuticals Corp. Sustained release delivery system
US6833408B2 (en) 1995-12-18 2004-12-21 Cohesion Technologies, Inc. Methods for tissue repair using adhesive materials
IT1277707B1 (en) 1995-12-22 1997-11-11 Chemedica Sa OPHTHALMIC FORMULATION BASED ON SODIUM HYALURONATE FOR USE IN OCULAR SURGERY
US5980948A (en) 1996-08-16 1999-11-09 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
IT1287967B1 (en) 1996-10-17 1998-09-10 Fidia Spa In Amministrazione S PHARMACEUTICAL PREPARATIONS FOR LOCAL ANESTHETIC USE
FR2759577B1 (en) 1997-02-17 1999-08-06 Corneal Ind DEEP SCLERECTOMY IMPLANT
FR2759576B1 (en) 1997-02-17 1999-08-06 Corneal Ind PRE-DESCEMETIC SCLERO-KERATECTOMY IMPLANT
US5935164A (en) 1997-02-25 1999-08-10 Pmt Corporaton Laminated prosthesis and method of manufacture
FR2764514B1 (en) 1997-06-13 1999-09-03 Biopharmex Holding Sa IMPLANT INJECTED IN SUBCUTANEOUS OR INTRADERMAL WITH CONTROLLED BIORESORBABILITY FOR REPAIR OR PLASTIC SURGERY AND AESTHETIC DERMATOLOGY
US7192984B2 (en) 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US6391336B1 (en) 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
FR2778336A1 (en) 1998-05-11 1999-11-12 Jean Pierre Perraud Injectable bioabsorbable implant for filling in wrinkles, cutaneous depressions and parodontal pockets
FR2780730B1 (en) 1998-07-01 2000-10-13 Corneal Ind INJECTABLE BIPHASIC COMPOSITIONS, ESPECIALLY USEFUL IN RESTORATIVE AND AESTHETIC SURGERIES
ITPD980169A1 (en) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl AMIDES OF HYALURONIC ACID AND ITS DERIVATIVES AND PROCESS FOR THEIR PREPARATION.
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
IT1303735B1 (en) 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S CROSS-LINKED HYALURONIC ACIDS AND THEIR MEDICAL USES.
IT1303738B1 (en) 1998-11-11 2001-02-23 Aquisitio S P A CARBOXYLATE POLYSACCHARIDE CROSS-LINKING PROCESS.
US20020016637A1 (en) * 1998-12-16 2002-02-07 Mark A. Anton Soft tissue filler
DK172900B1 (en) 1998-12-18 1999-09-27 Per Julius Nielsen Preparation and kit for use in intraocular surgery
GB9902412D0 (en) 1999-02-03 1999-03-24 Fermentech Med Ltd Process
GB9902652D0 (en) 1999-02-05 1999-03-31 Fermentech Med Ltd Process
US6767928B1 (en) 1999-03-19 2004-07-27 The Regents Of The University Of Michigan Mineralization and biological modification of biomaterial surfaces
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
CN1229685C (en) * 1999-12-16 2005-11-30 株式会社尼康 Bayonet mount
US6521223B1 (en) 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US6682760B2 (en) 2000-04-18 2004-01-27 Colbar R&D Ltd. Cross-linked collagen matrices and methods for their preparation
KR20010096388A (en) 2000-04-19 2001-11-07 진세훈 Human glans enhancing materials and glans enhancing method
FR2811671B1 (en) 2000-07-17 2003-02-28 Corneal Ind POLYMER (S) HYDROGEL, BIODEGRATION RESISTANT, PREPARATION AND USE AS TISSUE REGENERATION SUPPORT
FR2811996B1 (en) 2000-07-19 2003-08-08 Corneal Ind CROSS-LINKING OF POLYSACCHARIDE (S), PREPARATION OF HYDROGEL (S); POLYSACCHARIDE (S) AND HYDROGEL (S) OBTAINED, THEIR USES
WO2002009792A1 (en) 2000-07-28 2002-02-07 Anika Therapeutics, Inc. Bioabsorbable composites of derivatized hyaluronic acid
US6773723B1 (en) 2000-08-30 2004-08-10 Depuy Acromed, Inc. Collagen/polysaccharide bilayer matrix
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
JP4187917B2 (en) 2000-09-08 2008-11-26 独立行政法人科学技術振興機構 Method for producing glycosaminoglycan-collagen complex for tissue regeneration matrix
US6924273B2 (en) 2000-10-03 2005-08-02 Scott W. Pierce Chondroprotective/restorative compositions and methods of use thereof
AU2001294459A1 (en) 2000-10-06 2002-04-15 Jagotec Ag A controlled-release, parenterally administrable microparticle preparation
KR100375299B1 (en) 2000-10-10 2003-03-10 주식회사 엘지생명과학 Crosslinked derivatives of hyaluronic acid by amide formation and their preparation methods
WO2003053325A2 (en) 2000-12-13 2003-07-03 Purdue Research Foundation Microencapsulation of drugs by solvent exchange
US6979440B2 (en) 2001-01-29 2005-12-27 Salvona, Llc Compositions and method for targeted controlled delivery of active ingredients and sensory markers onto hair, skin, and fabric
US7119062B1 (en) 2001-02-23 2006-10-10 Neucoll, Inc. Methods and compositions for improved articular surgery using collagen
CA2445086C (en) * 2001-05-01 2008-04-08 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions
TW574301B (en) 2001-05-02 2004-02-01 Ind Tech Res Inst Manufacturing method of epoxide crosslinked polysaccharides matrix
US20050227936A1 (en) 2001-05-18 2005-10-13 Sirna Therapeutics, Inc. RNA interference mediated inhibition of TGF-beta and TGF-beta receptor gene expression using short interfering nucleic acid (siNA)
EP1411861B1 (en) 2001-06-29 2012-04-04 Medgraft Microtech, Inc. Biodegradable injectable implants and related methods of manufacture and use
US6749841B2 (en) 2001-07-26 2004-06-15 Revlon Consumer Products Corporation Stabilized aqueous acidic antiperspirant compositions and related methods
JP4230135B2 (en) 2001-08-21 2009-02-25 独立行政法人科学技術振興機構 Method for producing glycosaminoglycan-collagen complex cross-linked by multifunctional cross-linking agent
US20060189516A1 (en) 2002-02-19 2006-08-24 Industrial Technology Research Institute Method for producing cross-linked hyaluronic acid-protein bio-composites
JP3916516B2 (en) 2002-06-10 2007-05-16 独立行政法人科学技術振興機構 Scaffolding material for hard tissue-soft tissue interface regeneration
US6780366B2 (en) 2002-08-15 2004-08-24 Mentor Corporation Drip retainer
KR100523953B1 (en) 2002-08-27 2005-10-25 주식회사 엘지생명과학 Microbeads of natural polysaccharide and hyaluronic acid and processes for preparing the same
KR100507545B1 (en) 2002-09-03 2005-08-09 주식회사 엘지생명과학 Hyaluronic acid derivatives and processes for preparing them
US20040127932A1 (en) 2002-09-12 2004-07-01 Shah Tilak M. Dip-molded polymeric medical devices with reverse thickness gradient, and method of making same
DE10246340A1 (en) 2002-10-04 2004-04-29 Wohlrab, David, Dr. Combination preparation of hyaluronic acid and at least one local anesthetic and its use
US20040101959A1 (en) * 2002-11-21 2004-05-27 Olga Marko Treatment of tissue with undifferentiated mesenchymal cells
CN1732022A (en) 2002-12-30 2006-02-08 血管技术国际股份公司 Silk stent grafts
TWI251596B (en) 2002-12-31 2006-03-21 Ind Tech Res Inst Method for producing a double-crosslinked hyaluronate material
AU2003206922A1 (en) 2003-02-19 2004-09-09 Aventis Pharmaceuticals Holdings Inc. Composition and method for intradermal soft tissue augmentation
JP2006521180A (en) 2003-03-25 2006-09-21 バイオキュア・インコーポレーテッド Medical device with hydrogel yarn
FR2861734B1 (en) 2003-04-10 2006-04-14 Corneal Ind CROSSLINKING OF LOW AND HIGH MOLECULAR MASS POLYSACCHARIDES; PREPARATION OF INJECTABLE SINGLE PHASE HYDROGELS; POLYSACCHARIDES AND HYDROGELS OBTAINED
AU2003901834A0 (en) 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
JP2004323453A (en) 2003-04-25 2004-11-18 Chisso Corp Decomposable gel and method for producing the same
KR100931551B1 (en) 2003-05-13 2009-12-14 미마스 한도타이 고교 가부시키가이샤 Wafer Demount Method, Wafer Demount Device and Wafer Demount Conveyor
DE10323794A1 (en) * 2003-05-23 2004-12-09 Dr. Suwelack Skin & Health Care Ag Process for the production of alginate-containing porous moldings
BRPI0413086A (en) * 2003-07-30 2006-10-03 Anteis Sa complex matrix, use thereof, and process for preparing a poorly biodegradable biocompatible matrix
EP1681306B1 (en) 2003-10-29 2013-02-20 Teijin Limited Hyaluronic acid compound, hydrogel thereof and material for treating joint
CA2536041A1 (en) 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
US20060141049A1 (en) 2003-11-12 2006-06-29 Allergan, Inc. Triamcinolone compositions for intravitreal administration to treat ocular conditions
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20090148527A1 (en) 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
JP2007513650A (en) 2003-11-20 2007-05-31 アンジオテック インターナショナル アーゲー Implantable sensor and implantable pump and anti-scarring agent
US8124120B2 (en) 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
US8524213B2 (en) 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
US20050142152A1 (en) 2003-12-30 2005-06-30 Leshchiner Adelya K. Polymeric materials, their preparation and use
DE102004002001A1 (en) * 2004-01-14 2005-08-11 Reinmüller, Johannes, Dr.med. Agent for the treatment of inflammatory diseases
US7552442B1 (en) 2004-01-27 2009-06-23 Honeywell International Inc. Military data link integration apparatus and method
CA2536096A1 (en) 2004-01-30 2005-08-18 Angiotech International Ag Compositions and methods for treating contracture
FR2865737B1 (en) 2004-02-03 2006-03-31 Anteis Sa BIOCOMPATIBLE RETICLE GEL
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US8288362B2 (en) 2004-05-07 2012-10-16 S.K. Pharmaceuticals, Inc. Stabilized glycosaminoglycan preparations and related methods
EP1753787B1 (en) 2004-05-20 2016-10-19 Mentor Worldwide LLC Method of covalently linking hyaluronan and chitosan
CA2567532C (en) * 2004-05-20 2013-10-01 Mentor Corporation Methods for making injectable polymer hydrogels
WO2006002050A1 (en) 2004-06-15 2006-01-05 Encore Therapeutics, Inc. Phospholipid compositions and methods for their preparation and use
US20080124400A1 (en) 2004-06-24 2008-05-29 Angiotech International Ag Microparticles With High Loadings Of A Bioactive Agent
US20060040894A1 (en) 2004-08-13 2006-02-23 Angiotech International Ag Compositions and methods using hyaluronic acid
US20060040895A1 (en) 2004-08-19 2006-02-23 Kipling Thacker Aesthetic use of hyaluronan
US20060058238A1 (en) * 2004-09-15 2006-03-16 Lee Laurent-Applegate Fetal skin cell protein compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
US7414021B2 (en) 2004-10-01 2008-08-19 Vincent Carmine Giampapa Method and composition for restoration of age related tissue loss in the face or selected areas of the body
KR100762928B1 (en) 2004-10-29 2007-10-04 재단법인서울대학교산학협력재단 Nonwoven Nanofibrous Membranes of Silk Fibroin for Guided Bone Tissue Regeneration and Their Preparation Method
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
US8481080B2 (en) 2004-11-24 2013-07-09 Novozymes Biopolymer A/S Method of cross-linking hyaluronic acid with divinulsulfone
FR2878444B1 (en) 2004-11-30 2008-04-25 Corneal Ind Soc Par Actions Si VISCOELASTIC SOLUTIONS COMPRISING SODIUM HYALURONATE AND HYDROXYPROPYLMETHYLCELLULOSE, PREPARATION AND USES
WO2006067608A1 (en) 2004-12-22 2006-06-29 Laboratoire Medidom S.A. Aqueous formulations based on sodium hyaluronate for parenteral use
WO2006102676A1 (en) 2005-03-23 2006-09-28 Tissue Engineering Refraction, Inc. Injectable polyethylene oxide dermal fillers and related devices
EP1893174A2 (en) 2005-05-10 2008-03-05 Cytophil, Inc. Injectable hydrogels and methods of making and using same
EP1726299A3 (en) 2005-05-27 2007-04-18 StratoSphere Pharma AB Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
US7491709B2 (en) 2005-07-01 2009-02-17 Wayne Carey Treatment with hyaluronic acid
WO2007018124A1 (en) 2005-08-11 2007-02-15 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Agent for enhancing collagen production and utilization of the same
JP4982718B2 (en) 2005-08-31 2012-07-25 株式会社林原 Composition for oral intake for beautiful skin
EP1951762B1 (en) 2005-10-03 2018-02-07 PINSKY, Mark A. Compositions and methods for improved skin care
EP1968614A2 (en) 2005-12-14 2008-09-17 Anika Therapeutics Inc. Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid
WO2007070617A1 (en) 2005-12-14 2007-06-21 Anika Therapeutics, Inc. Bioabsorbable implant of hyaluronic acid derivative for treatment of osteochondral and chondral defects
FR2894827B1 (en) 2005-12-21 2010-10-29 Galderma Res & Dev PHARMACEUTICAL OR COSMETIC PREPARATIONS FOR TOPICAL AND / OR PARENTERAL APPLICATION, PROCESSES FOR THEIR PREPARATION, AND USES THEREOF
FR2895907B1 (en) 2006-01-06 2012-06-01 Anteis Sa VISCOELASTIC GEL FOR DERMATOLOGICAL USE
US20070184087A1 (en) 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US20070212385A1 (en) 2006-03-13 2007-09-13 David Nathaniel E Fluidic Tissue Augmentation Compositions and Methods
JP2009529967A (en) 2006-03-15 2009-08-27 サーモディクス,インコーポレイティド Hydrophobic derivatives of natural biodegradable polysaccharides and their use
FR2900575B1 (en) * 2006-05-05 2008-10-17 Anteis Sa BIOCOMPATIBLE CONTROLLED RELEASE GEL, PREPARATION METHOD AND USE THEREOF
US8378064B2 (en) 2006-05-19 2013-02-19 Trustees Of Boston University Hydrophilic polymers as medical lubricants and gels
US20070298005A1 (en) 2006-06-22 2007-12-27 Marie-Josee Thibault Injectable composition for treatment of skin defects or deformations
WO2008003321A2 (en) 2006-07-07 2008-01-10 Novozymes Biopolymer A/S Compositions with several hyaluronic acid fractions for cosmetic use
JP4557939B2 (en) 2006-07-18 2010-10-06 株式会社ジェイテック X-ray mirror high-precision attitude control method and X-ray mirror
US20100035838A1 (en) 2006-09-19 2010-02-11 Geoffrey Kenneth Heber Cross-linked polysaccharide gels
FR2908415B1 (en) 2006-11-10 2009-01-23 Abr Dev Sarl RETICULATED HYALURONIC ACID AND PROCESS FOR PREPARING THE SAME
FR2909560B1 (en) 2006-12-06 2012-12-28 Fabre Pierre Dermo Cosmetique HYALURONIC ACID GEL FOR INTRADERMAL INJECTION
EP2121026B1 (en) 2006-12-11 2017-06-28 CHIT2GEL Ltd. Novel injectable chitosan mixtures forming hydrogels
KR100759091B1 (en) 2006-12-13 2007-09-17 조강선 Dermal filler composition
ATE545436T1 (en) 2006-12-22 2012-03-15 Croma Pharma Ges M B H USE OF THIOLATED POLYSACCHARIDES FOR TISSUE BUILDING
WO2008088922A2 (en) 2007-01-19 2008-07-24 Genentech, Inc. Prevention of hydrogel viscosity loss
CA2677498C (en) 2007-02-05 2016-05-17 Carbylan Biosurgery, Inc. Polymer formulations for delivery of bioactive agents
WO2008098007A1 (en) 2007-02-05 2008-08-14 Freedom-2, Inc. Tissue fillers and methods of using the same
US7776840B2 (en) 2007-02-21 2010-08-17 Cutanea Life Sciences, Inc. Methods of use of biomaterial and injectable implant containing biomaterial
US7939578B2 (en) 2007-02-23 2011-05-10 3M Innovative Properties Company Polymeric fibers and methods of making
US8642067B2 (en) 2007-04-02 2014-02-04 Allergen, Inc. Methods and compositions for intraocular administration to treat ocular conditions
US11078262B2 (en) 2007-04-30 2021-08-03 Allergan, Inc. High viscosity macromolecular compositions for treating ocular conditions
US20100323985A1 (en) 2007-05-11 2010-12-23 Marc Moutet Pharmaceutical or cosmetic preparations for topical and/or parenteral application, preparation methods thereof and use of same
EP2155149A2 (en) 2007-05-11 2010-02-24 Galderma Research & Development Pharmaceutical or cosmetic preparations for topical and/or parenteral application, preparation methods thereof and use of same
US20080293637A1 (en) 2007-05-23 2008-11-27 Allergan, Inc. Cross-linked collagen and uses thereof
JP2010528039A (en) 2007-05-23 2010-08-19 アラーガン、インコーポレイテッド Coated hyaluronic acid particles
WO2008157608A1 (en) 2007-06-18 2008-12-24 Cartlix, Inc. Composite scaffolds for tissue regeneration
US9011894B2 (en) 2007-06-29 2015-04-21 Carbylan Therapeutics, Inc. Sterile hyaluronic acid polymer compositions and related methods
CA2694700C (en) 2007-07-27 2015-04-14 Humacyte, Inc. Compositions and methods for soft tissue augmentation
SI2182960T1 (en) 2007-07-27 2014-07-31 Galderma Laboratories Inc. Compounds, formulations, and methods for reducing skin wrinkles, creasing and sagging
US20120071437A1 (en) 2007-07-30 2012-03-22 Allergan, Inc. Tunable crosslinked polysaccharide compositions
US20110077737A1 (en) 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US8318695B2 (en) 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
US8455459B2 (en) 2007-08-02 2013-06-04 Medicis Pharmaceutical Corporation Method of applying an injectable filler
FR2920000B1 (en) 2007-08-13 2010-01-29 Oreal COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING HYALURONIC ACID, AND COSMETIC PROCESS FOR DECREASING SIGNS OF AGING
CA2734577A1 (en) 2007-08-16 2009-02-26 Carnegie Mellon University Inflammation-regulating compositions and methods
KR100813224B1 (en) 2007-08-24 2008-03-13 한양대학교 산학협력단 Thermo-reversible coacervate combination gels for protein delivery
FR2920968B1 (en) 2007-09-14 2009-11-13 Oreal COSMETIC PROCESS FOR AESTHETIC TREATMENT AND / OR REPAIR OF SKIN
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
US7910134B2 (en) 2007-10-29 2011-03-22 Ayman Boutros Alloplastic injectable dermal filler and methods of use thereof
JP5035900B2 (en) 2007-11-21 2012-09-26 株式会社アイ・エイチ・アイ マリンユナイテッド Temperature distribution history estimation method
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8394784B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
FR2924615B1 (en) 2007-12-07 2010-01-22 Vivacy Lab HYDROGEL COHESIVE BIODEGRADABLE.
US9161970B2 (en) 2007-12-12 2015-10-20 Allergan, Inc. Dermal filler
EP2222270B1 (en) 2007-12-26 2018-11-14 Mark A. Pinsky Collagen formulations for improved skin care
US20090291986A1 (en) 2008-05-22 2009-11-26 Apostolos Pappas Composition and method of treating facial skin defect
US20090297632A1 (en) 2008-06-02 2009-12-03 Waugh Jacob M Device, Methods and Compositions to Alter Light Interplay with Skin
WO2010003797A1 (en) 2008-07-09 2010-01-14 Novozymes Biopharma Dk A/S Hyaluronic acid for corneal wound healing
US20130102563A1 (en) * 2008-08-04 2013-04-25 Allergan, Inc. Dermal filler with lidocaine
US8450475B2 (en) 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP3184552B1 (en) 2008-09-02 2020-08-12 Tautona Group LP Threads of hyaluronic acid, methods of making thereof and uses thereof
EP2341953B1 (en) 2008-09-04 2018-11-21 The General Hospital Corporation Hydrogels for vocal cord and soft tissue augmentation and repair
GB0816496D0 (en) 2008-09-10 2008-10-15 Zhao Xiaobin Hyaluronic acid cryogel
JP5683957B2 (en) 2008-09-30 2015-03-11 電気化学工業株式会社 Photo-stabilized pharmaceutical composition
US20100098794A1 (en) 2008-10-17 2010-04-22 Armand Gerard Topical anti-wrinkle and anti-aging moisturizing cream
US20100111919A1 (en) 2008-10-31 2010-05-06 Tyco Healthcare Group Lp Delayed gelation compositions and methods of use
WO2010053918A1 (en) 2008-11-05 2010-05-14 Hancock Jaffe Laboratories, Inc. Composite containing collagen and elastin as a dermal expander and tissue filler
DK2365829T3 (en) 2008-11-07 2017-07-31 Klox Tech Inc COMBINATION OF AN OXIDANT AND PHOTO ACTIVATOR FOR HEALING OF WOES
FR2938187B1 (en) 2008-11-07 2012-08-17 Anteis Sa INJECTABLE COMPOSITION BASED ON HYALURONIC ACID OR ONE OF ITS HEAT-STERILIZED SALTS, POLYOLS AND LIDOCAINE
ITRM20080636A1 (en) 2008-11-28 2010-05-29 Univ Palermo PROCEDURE FOR THE PRODUCTION OF FUNCTIONAL DERIVATIVES OF HYALURONIC ACID AND RELATIVE HYDROGELS.
US20100136070A1 (en) 2008-12-03 2010-06-03 Jakk Group, Inc. Methods, devices, and compositions for dermal filling
SE533818C2 (en) 2009-02-04 2011-01-25 Roxtec Ab Eccentric part of a pipe or cable entry
PL2236523T3 (en) 2009-03-30 2018-07-31 Scivision Biotech Inc. Method for producing cross-linked hyaluronic acid
EP2413894B1 (en) 2009-04-02 2017-01-04 Allergan, Inc. Hair-like shaped hydrogels for soft tissue augmentation
US9371402B2 (en) 2009-04-09 2016-06-21 Scivision Biotech Inc. Method for producing cross-linked hyaluronic acid
KR101453601B1 (en) 2009-05-29 2014-10-22 갈데르마 리써어치 앤드 디벨로프먼트 Injectable combination of adrenergic receptor agonists with fillers, for decreasing skin reactions due to injection
IT1395392B1 (en) 2009-08-27 2012-09-14 Fidia Farmaceutici VISCOELASTIC FROSTS LIKE NEW FILLERS
US8657795B2 (en) 2009-12-30 2014-02-25 Cook Medical Technologies Llc Vascular port
US20110171286A1 (en) 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US20110171311A1 (en) 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
DE102010009460A1 (en) 2010-02-26 2011-09-01 Siemens Aktiengesellschaft Method for transmitting a plurality of medical image data sets and system for managing image data sets
NZ602405A (en) 2010-03-12 2014-12-24 Allergan Ind Sas A fluid composition comprising a hyaluronan polymer and mannitol for improving skin conditions
AU2011229730B2 (en) 2010-03-22 2016-01-07 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
CA2815141A1 (en) 2010-10-20 2012-04-26 Tautona Group Lp Threads of cross-linked hyaluronic acid and methods of preparation and use thereof
US9299476B2 (en) 2010-10-22 2016-03-29 Newsouth Innovations Pty Limited Polymeric material
FR2968306B1 (en) 2010-12-06 2014-02-28 Teoxane PROCESS FOR PREPARING RETICULATED GEL
FR2968305B1 (en) 2010-12-06 2014-02-28 Teoxane PROCESS FOR PREPARING RETICULATED GEL
US20120142628A1 (en) * 2010-12-07 2012-06-07 Allergan, Inc. Methods for treating crepitus
US8793408B2 (en) 2010-12-21 2014-07-29 Nikon Corporation Electronic device and program
US20140178512A1 (en) 2011-02-22 2014-06-26 Merz Pharma Gmbh & Co. Kgaa In situ formation of a filler
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
EP3536307B1 (en) 2011-06-03 2021-10-20 ALLERGAN Industrie, SAS Dermal filler compositions including antioxidants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130116411A1 (en) 2011-09-06 2013-05-09 Allergan, Inc. Methods of making hyaluronic acid/collagen compositions
US20130116190A1 (en) 2011-09-06 2013-05-09 Allergan, Inc. Hyaluronic acid-collagen matrices for tissue engineering
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US20140011980A1 (en) 2012-07-03 2014-01-09 Allergan, Inc. Methods for sterilizing compositions and resulting compositions
US9627808B2 (en) 2015-04-13 2017-04-18 Tyco Electronics Brasil Ltda One piece connector with integral latching members

Also Published As

Publication number Publication date
ES2622708T3 (en) 2017-07-07
CA2944734A1 (en) 2010-02-11
ES2599763T3 (en) 2017-02-03
EP3205332A1 (en) 2017-08-16
CA3209175A1 (en) 2010-02-11
CA3112106C (en) 2023-10-17
US9089518B2 (en) 2015-07-28
CA2732788C (en) 2017-01-10
US20120172328A1 (en) 2012-07-05
US8450475B2 (en) 2013-05-28
SG10201505441TA (en) 2015-08-28
US9089519B2 (en) 2015-07-28
US20110118206A1 (en) 2011-05-19
JP2011529763A (en) 2011-12-15
US20130041039A1 (en) 2013-02-14
CA2944734C (en) 2018-12-18
BRPI0917588B1 (en) 2018-03-13
ES2780190T3 (en) 2020-08-24
JP5808848B2 (en) 2015-11-10
CA2732928A1 (en) 2010-02-11
SI2326302T1 (en) 2017-01-31
JP5670899B2 (en) 2015-02-18
US20190343990A1 (en) 2019-11-14
KR101747441B1 (en) 2017-06-14
RU2011107878A (en) 2012-09-10
PT2326302T (en) 2016-11-02
US20190076580A1 (en) 2019-03-14
US11173232B2 (en) 2021-11-16
US20130244970A1 (en) 2013-09-19
MX342613B (en) 2016-10-06
AU2009278884A1 (en) 2010-02-11
US20210283313A1 (en) 2021-09-16
US20200086009A1 (en) 2020-03-19
DK2326302T3 (en) 2016-11-14
US9089517B2 (en) 2015-07-28
US8357795B2 (en) 2013-01-22
US20140148406A1 (en) 2014-05-29
US10485896B2 (en) 2019-11-26
US20220313870A1 (en) 2022-10-06
BRPI0917573A2 (en) 2017-07-11
CN102170855A (en) 2011-08-31
US10328180B2 (en) 2019-06-25
US20100028438A1 (en) 2010-02-04
EP2674147B1 (en) 2020-01-01
EP2323617A1 (en) 2011-05-25
EP2323617B1 (en) 2017-01-18
HUE048366T2 (en) 2020-08-28
PL2323617T3 (en) 2017-08-31
US8822676B2 (en) 2014-09-02
US20150045321A1 (en) 2015-02-12
CN102170855B (en) 2013-04-24
PL2674147T3 (en) 2020-11-16
AU2009278883B2 (en) 2015-08-06
US20100028437A1 (en) 2010-02-04
BRPI0917573B1 (en) 2018-03-13
WO2010015900A1 (en) 2010-02-11
CA3023168C (en) 2021-05-04
DK2674147T3 (en) 2020-03-30
HK1156883A1 (en) 2012-06-22
JP5670900B2 (en) 2015-02-18
JP2016000350A (en) 2016-01-07
JP2014237718A (en) 2014-12-18
RU2496473C2 (en) 2013-10-27
BRPI0917588A2 (en) 2017-07-11
EP2326302A1 (en) 2011-06-01
US11020512B2 (en) 2021-06-01
US20130041038A1 (en) 2013-02-14
MX2011001322A (en) 2011-07-29
US9238013B2 (en) 2016-01-19
CY1118281T1 (en) 2017-06-28
US20180000992A1 (en) 2018-01-04
CA3023168A1 (en) 2010-02-11
PT2323617T (en) 2017-04-24
CA2732788A1 (en) 2010-02-11
KR101672562B1 (en) 2016-11-03
EP3988082A1 (en) 2022-04-27
US20140213547A1 (en) 2014-07-31
KR20110040966A (en) 2011-04-20
DK2323617T3 (en) 2017-04-24
US20130131011A1 (en) 2013-05-23
PL2326302T3 (en) 2017-01-31
US10391202B2 (en) 2019-08-27
CN102170856A (en) 2011-08-31
US20150297790A1 (en) 2015-10-22
SI2323617T1 (en) 2017-07-31
CN102170856B (en) 2013-05-22
CN103285423A (en) 2013-09-11
CN103285423B (en) 2014-11-26
EP3662889A1 (en) 2020-06-10
US9358322B2 (en) 2016-06-07
AU2009278883A1 (en) 2010-02-11
RU2011107877A (en) 2012-09-10
MX2011001321A (en) 2011-03-25
CA3112106A1 (en) 2010-02-11
KR20110043730A (en) 2011-04-27
JP2011529762A (en) 2011-12-15
EP2674147A1 (en) 2013-12-18
US20160279296A1 (en) 2016-09-29
JP2014237719A (en) 2014-12-18
US20190134275A9 (en) 2019-05-09
RU2496474C2 (en) 2013-10-27
EP2326302B1 (en) 2016-07-27
HUE031598T2 (en) 2017-07-28
US20140213546A1 (en) 2014-07-31
HUE031483T2 (en) 2017-07-28
HK1189518A1 (en) 2014-06-13
WO2010015901A1 (en) 2010-02-11
US20190076579A1 (en) 2019-03-14
US20190350832A1 (en) 2019-11-21
CY1118821T1 (en) 2018-01-10
AU2009278884B2 (en) 2013-07-04

Similar Documents

Publication Publication Date Title
HK1189518A1 (en) Hyaluronic acid-based gels including anesthetic agents
GB0811304D0 (en) Therapeutic agents
GB0908957D0 (en) Therapeutic agents
GB0811643D0 (en) New therapeutic agents
GB0819593D0 (en) Therapeutic agents
GB0821693D0 (en) Therapeutic agents
GB0812309D0 (en) Therapeutic agents
GB0805818D0 (en) Therapeutic agents
GB0801080D0 (en) Therapeutic agents
GB0801081D0 (en) Therapeutic agents
GB0803054D0 (en) Medicament
EP2454276A4 (en) Therapeutic agents
GB0811715D0 (en) Therapeutic agents
GB0910493D0 (en) Therapeutic agents
GB0800487D0 (en) Therapeutic use
GB0800489D0 (en) Therapeutic use
GB0801410D0 (en) Therapeutic intervention
GB0812563D0 (en) Therapeutic agents
GB0801082D0 (en) Therapeutic agents
GB0812558D0 (en) Therapeutic agents
GB0820275D0 (en) Therapeutic agents
GB0815177D0 (en) Therapeutic agents
GB0803395D0 (en) Medicament
GB0817737D0 (en) New therapeutic use
GB0817738D0 (en) New therapeutic use