SG11201913229PA - Silk-hyaluronic acid based tissue fillers and methods of using the same - Google Patents

Silk-hyaluronic acid based tissue fillers and methods of using the same

Info

Publication number
SG11201913229PA
SG11201913229PA SG11201913229PA SG11201913229PA SG11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA SG 11201913229P A SG11201913229P A SG 11201913229PA
Authority
SG
Singapore
Prior art keywords
silk
methods
same
hyaluronic acid
acid based
Prior art date
Application number
SG11201913229PA
Inventor
Gregory H Altman
Peng Xu
Erlei Jin
Original Assignee
Evolved By Nature Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolved By Nature Inc filed Critical Evolved By Nature Inc
Publication of SG11201913229PA publication Critical patent/SG11201913229PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52Hydrogels or hydrocolloids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11201913229PA 2017-06-26 2018-06-26 Silk-hyaluronic acid based tissue fillers and methods of using the same SG11201913229PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762525131P 2017-06-26 2017-06-26
US201862641095P 2018-03-09 2018-03-09
PCT/US2018/039574 WO2019005848A1 (en) 2017-06-26 2018-06-26 Silk-hyaluronic acid based tissue fillers and methods of using the same

Publications (1)

Publication Number Publication Date
SG11201913229PA true SG11201913229PA (en) 2020-01-30

Family

ID=64742709

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201913229PA SG11201913229PA (en) 2017-06-26 2018-06-26 Silk-hyaluronic acid based tissue fillers and methods of using the same

Country Status (14)

Country Link
US (1) US20230338614A1 (en)
EP (2) EP3645063B1 (en)
JP (2) JP2020525253A (en)
KR (1) KR20200032103A (en)
CN (1) CN111263646A (en)
AU (1) AU2018290810B2 (en)
CA (1) CA3068296A1 (en)
CO (1) CO2020000774A2 (en)
ES (1) ES2935887T3 (en)
IL (2) IL299584A (en)
MA (1) MA49520A (en)
SG (1) SG11201913229PA (en)
UA (1) UA127350C2 (en)
WO (1) WO2019005848A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11660372B2 (en) 2017-06-26 2023-05-30 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue fillers and methods of using the same

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111032930B (en) 2017-09-21 2024-01-02 住友电气工业株式会社 Semi-insulating gallium arsenide crystal substrate
US20230114250A1 (en) * 2018-12-19 2023-04-13 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same
WO2020205774A1 (en) * 2019-03-29 2020-10-08 Trustees Of Tufts College Crosslinked silk fibroin-based compositions, and methods of making and using the same
EP3979873A4 (en) * 2019-06-06 2023-08-16 Evolved by Nature, Inc. Silk stimulated collagen production and methods of use thereof
WO2020262596A1 (en) * 2019-06-26 2020-12-30 Compagnie Generale Des Etablissements Michelin A noise improving tread
CN110339398A (en) * 2019-07-18 2019-10-18 王月玲 One kind Amvisc containing amino acid and preparation method thereof
WO2021035087A1 (en) * 2019-08-20 2021-02-25 Evolved By Nature, Inc. Silk personal care compositions
WO2021060934A1 (en) * 2019-09-27 2021-04-01 주식회사 엘지화학 Method for preparing polymer microparticles, polymer microparticles, medical composition comprising same, cosmetic composition, medical article, and cosmetic article
WO2021123247A1 (en) * 2019-12-19 2021-06-24 Croma-Pharma Gmbh Thiol-modified hyaluronan and hydrogel comprising the crosslinked hyaluronan
EP4167949A4 (en) * 2020-06-19 2024-05-15 Evolved by Nature, Inc. Silk-hyaluronic acid compositions for tissue filling, tissue spacing, and tissue bulking
EP4149277A1 (en) 2021-05-21 2023-03-22 Cambridge Crops, Inc. d/b/a Mori Systems and methods for manufacturing a silk fibroin solution and powders containing silk fibroin
EP4362993A1 (en) * 2021-06-30 2024-05-08 Merz Pharma GmbH & Co. KGaA Hyaluronic acid dermal fillers crosslinked with polyethylene glycol diglycidyl ether, method for making same and uses thereof
CN113368220A (en) * 2021-07-05 2021-09-10 云南维他源生物科技有限公司 AHCO composition, and preparation and application thereof
KR20230013682A (en) 2021-07-16 2023-01-27 주식회사 휴메딕스 Hyaluronic acid filler crosslinked by PEGDE and method for preparing the same
US11864569B2 (en) 2021-08-16 2024-01-09 Cambridge Crops, Inc. Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH564031A5 (en) 1968-03-29 1975-07-15 Anvar
FR2334107A1 (en) 1975-12-05 1977-07-01 Pasteur Institut METHOD OF COUPLING BIOLOGICAL SUBSTANCES BY COVALENT BONDS
US4355023A (en) 1980-09-30 1982-10-19 The Massachusetts General Hospital Antibody fragment compositions and process
US4657853A (en) 1984-09-14 1987-04-14 E. I. Du Pont De Nemours And Company Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US20060105022A1 (en) 2004-11-15 2006-05-18 Shiseido Co., Ltd. Process for preparing crosslinked hyaluronic acid gel
US8450475B2 (en) * 2008-08-04 2013-05-28 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
US20110189292A1 (en) 2009-04-20 2011-08-04 Allergan, Inc. Dermal fillers comprising silk fibroin hydrogels and uses thereof
WO2011059325A2 (en) * 2009-11-11 2011-05-19 University Of Twente, Institute For Biomedical Technology And Technical Medicine (Mira) Dextran-hyaluronic acid based hydrogels
EP3536307B1 (en) * 2011-06-03 2021-10-20 ALLERGAN Industrie, SAS Dermal filler compositions including antioxidants
RU2626513C2 (en) * 2011-09-14 2017-07-28 Аллерган, Инк. Dermal filler composition for small wrinkles treating
CN102836465B (en) * 2012-08-30 2014-06-04 浙江星月生物科技股份有限公司 Silk-fibroi and hyaluronic-acid (HA) composite gel for injection and preparation and application thereof
WO2014055895A1 (en) * 2012-10-05 2014-04-10 Allergan, Inc. Injectable device and method for sculpting, augmenting or correcting facial features such as the chin
US20140315828A1 (en) * 2013-04-22 2014-10-23 Allergan, Inc. Cross-linked silk-hyaluronic acid compositions
US10077320B2 (en) 2013-06-28 2018-09-18 Galderma S.A. Process for preparing a cross-linked hyaluronic acid product
BR112016006898A8 (en) 2013-09-30 2020-02-18 Silk Therapeutics Inc composition, films, method for reducing fine lines and wrinkles, gels, method for smoothing and rejuvenating human skin, serum, method for moisturizing human skin, skin peeling composition and method for preparing a solution
JP6946187B2 (en) 2014-12-02 2021-10-06 エボルブド バイ ネイチャー, インコーポレイテッド Silk performance garments and products, and how to manufacture them
JP7290912B2 (en) * 2015-04-29 2023-06-14 エボルブド バイ ネイチャー, インコーポレイテッド Silk-based wetting agent composition and method
US10175996B2 (en) 2016-05-02 2019-01-08 Norman R. Byrne Information display and control for work areas
WO2018039496A1 (en) * 2016-08-24 2018-03-01 Allergan, Inc. Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11660372B2 (en) 2017-06-26 2023-05-30 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue fillers and methods of using the same

Also Published As

Publication number Publication date
UA127350C2 (en) 2023-07-26
JP2020525253A (en) 2020-08-27
EP3645063B1 (en) 2022-09-28
JP2023139249A (en) 2023-10-03
EP3645063A4 (en) 2021-04-14
BR112019027687A2 (en) 2020-09-15
AU2018290810B2 (en) 2024-06-13
IL271692B2 (en) 2023-06-01
EP3645063A1 (en) 2020-05-06
US20230338614A1 (en) 2023-10-26
KR20200032103A (en) 2020-03-25
ES2935887T3 (en) 2023-03-13
CN111263646A (en) 2020-06-09
EP4169539A1 (en) 2023-04-26
IL299584A (en) 2023-03-01
AU2018290810A1 (en) 2020-02-13
IL271692A (en) 2020-02-27
MA49520A (en) 2021-04-14
CA3068296A1 (en) 2019-01-03
WO2019005848A1 (en) 2019-01-03
CO2020000774A2 (en) 2020-05-05

Similar Documents

Publication Publication Date Title
IL271692A (en) Silk-hyaluronic acid based tissue fillers and methods of using the same
IL268406A (en) Compositions and methods for the treatment of hemoglobinopathies
HK1258205A1 (en) Compositions and methods for the treatment of hemoglobinopathies
EP3474785A4 (en) Spinal implant and methods of using the same
EP3356517A4 (en) Spontaneously beating cardiac organoid constructs and integrated body-on-chip apparatus containing the same
EP3303634A4 (en) Cas9 variants and methods of use thereof
EP3325473A4 (en) Compounds and uses thereof in the treatment of cancers and other medical conditions
EP3397149A4 (en) Tissue mapping and treatment
HK1253769A1 (en) Methods and compositions for the diagnosis and for the treatment of adrenoleukodystrophy
GB201513461D0 (en) Methods and devices for the production of decellularised tissue scaffolds
EP3432933A4 (en) Biocompatible adhesives and methods of use thereof
EP3185795A4 (en) Bone fixation devices and methods
EP3242709A4 (en) Cardiac stimulation of atrial-ventricle pathways and/or associated tissue
EP3474869A4 (en) Human tissue derived compositions and uses thereof
EP3154533A4 (en) Methods of anesthetizing nerve tissue in the trigeminal nerve pathway and medical uses thereof
IL284082A (en) Silk-hyaluronic acid tissue fillers and methods of making and using the same
IL275182A (en) Compositions and methods for the treatment of metabolic conditions
IL272937A (en) Compositions and methods for the treatment of fibrotic diseases
EP3496804A4 (en) Bioelectric devices and methods of use
EP3209340A4 (en) Microfabricated tissue scaffolds and methods of making and using the same
IL248210A0 (en) Methods and compositions for the treatment of vascular malformation
GB201709840D0 (en) Methods and medical uses
EP3341006A4 (en) Compositions and methods for the treatment of neurodamage
ZA201900984B (en) Methods and compositions for the treatment of warts
HK1258999A1 (en) Compositions, methods, and medical compositions for treatment of and maintaining the health of the liver