AU2014364805B2 - Anti-CD3 antibodies and methods of use - Google Patents

Anti-CD3 antibodies and methods of use Download PDF

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Publication number
AU2014364805B2
AU2014364805B2 AU2014364805A AU2014364805A AU2014364805B2 AU 2014364805 B2 AU2014364805 B2 AU 2014364805B2 AU 2014364805 A AU2014364805 A AU 2014364805A AU 2014364805 A AU2014364805 A AU 2014364805A AU 2014364805 B2 AU2014364805 B2 AU 2014364805B2
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amino acid
acid sequence
seq
domain
hvr
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AU2014364805A1 (en
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Xiaocheng Chen
Mark S. Dennis
Allen J. Ebens Jr.
Teemu T. Junttila
Robert F. Kelley
Mary A. Mathieu
Liping L. SUN
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Genentech Inc
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Genentech Inc
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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AU2014364805A 2013-12-17 2014-12-17 Anti-CD3 antibodies and methods of use Active AU2014364805B2 (en)

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