BR112016014022A2 - anticorpos anti-cd3, ácido nucleico isolado, vetor, célula hospedeira, método de produção do anticorpo anti-cd3, imunoconjugado, composição, uso do anticorpo anti-cd3, métodos de tratamento, métodos de intensificação da função imune e kit - Google Patents

anticorpos anti-cd3, ácido nucleico isolado, vetor, célula hospedeira, método de produção do anticorpo anti-cd3, imunoconjugado, composição, uso do anticorpo anti-cd3, métodos de tratamento, métodos de intensificação da função imune e kit

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Publication number
BR112016014022A2
BR112016014022A2 BR112016014022A BR112016014022A BR112016014022A2 BR 112016014022 A2 BR112016014022 A2 BR 112016014022A2 BR 112016014022 A BR112016014022 A BR 112016014022A BR 112016014022 A BR112016014022 A BR 112016014022A BR 112016014022 A2 BR112016014022 A2 BR 112016014022A2
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Brazil
Prior art keywords
antibody
methods
antibodies
immunoconjugate
kit
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BR112016014022A
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English (en)
Other versions
BR112016014022B1 (pt
Inventor
J Ebens Allen Jr
L Sun Liping
S Dennis Mark
A Mathieu Mary
F Kelley Robert
T Junttila Teemu
Chen Xiaocheng
Original Assignee
Genentech Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52394341&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112016014022(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112016014022A2 publication Critical patent/BR112016014022A2/pt
Publication of BR112016014022B1 publication Critical patent/BR112016014022B1/pt

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K16/283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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Abstract

a invenção fornece anticorpos anti-grupo de diferenciação 3 (cd3) e métodos de uso dos mesmos.
BR112016014022-2A 2013-12-17 2014-12-17 Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, usos do anticorpo biespecífico e kit BR112016014022B1 (pt)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361917346P 2013-12-17 2013-12-17
US61/917,346 2013-12-17
US201461949950P 2014-03-07 2014-03-07
US61/949,950 2014-03-07
US201462026594P 2014-07-18 2014-07-18
US62/026,594 2014-07-18
US201462053582P 2014-09-22 2014-09-22
US62/053,582 2014-09-22
US201462091441P 2014-12-12 2014-12-12
US62/091,441 2014-12-12
PCT/US2014/070951 WO2015095392A1 (en) 2013-12-17 2014-12-17 Anti-cd3 antibodies and methods of use

Publications (2)

Publication Number Publication Date
BR112016014022A2 true BR112016014022A2 (pt) 2019-10-01
BR112016014022B1 BR112016014022B1 (pt) 2023-04-18

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BR122021025085-5A BR122021025085B1 (pt) 2013-12-17 2014-12-17 Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, uso do anticorpo biespecífico e kit
BR122021025087-1A BR122021025087B1 (pt) 2013-12-17 2014-12-17 Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, uso do anticorpo biespecífico e kit
BR112016014022-2A BR112016014022B1 (pt) 2013-12-17 2014-12-17 Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, usos do anticorpo biespecífico e kit

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