BR112016014022A2 - anticorpos anti-cd3, ácido nucleico isolado, vetor, célula hospedeira, método de produção do anticorpo anti-cd3, imunoconjugado, composição, uso do anticorpo anti-cd3, métodos de tratamento, métodos de intensificação da função imune e kit - Google Patents
anticorpos anti-cd3, ácido nucleico isolado, vetor, célula hospedeira, método de produção do anticorpo anti-cd3, imunoconjugado, composição, uso do anticorpo anti-cd3, métodos de tratamento, métodos de intensificação da função imune e kitInfo
- Publication number
- BR112016014022A2 BR112016014022A2 BR112016014022A BR112016014022A BR112016014022A2 BR 112016014022 A2 BR112016014022 A2 BR 112016014022A2 BR 112016014022 A BR112016014022 A BR 112016014022A BR 112016014022 A BR112016014022 A BR 112016014022A BR 112016014022 A2 BR112016014022 A2 BR 112016014022A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibody
- methods
- antibodies
- immunoconjugate
- kit
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000002708 enhancing effect Effects 0.000 title 1
- 230000036737 immune function Effects 0.000 title 1
- 229940127121 immunoconjugate Drugs 0.000 title 1
- 230000016784 immunoglobulin production Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 230000003540 anti-differentiation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/00—Immunoglobulins specific features
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- C07K2317/00—Immunoglobulins specific features
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Abstract
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361917346P | 2013-12-17 | 2013-12-17 | |
US61/917,346 | 2013-12-17 | ||
US201461949950P | 2014-03-07 | 2014-03-07 | |
US61/949,950 | 2014-03-07 | ||
US201462026594P | 2014-07-18 | 2014-07-18 | |
US62/026,594 | 2014-07-18 | ||
US201462053582P | 2014-09-22 | 2014-09-22 | |
US62/053,582 | 2014-09-22 | ||
US201462091441P | 2014-12-12 | 2014-12-12 | |
US62/091,441 | 2014-12-12 | ||
PCT/US2014/070951 WO2015095392A1 (en) | 2013-12-17 | 2014-12-17 | Anti-cd3 antibodies and methods of use |
Publications (2)
Publication Number | Publication Date |
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BR112016014022A2 true BR112016014022A2 (pt) | 2019-10-01 |
BR112016014022B1 BR112016014022B1 (pt) | 2023-04-18 |
Family
ID=52394341
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR122021025085-5A BR122021025085B1 (pt) | 2013-12-17 | 2014-12-17 | Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, uso do anticorpo biespecífico e kit |
BR122021025087-1A BR122021025087B1 (pt) | 2013-12-17 | 2014-12-17 | Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, uso do anticorpo biespecífico e kit |
BR112016014022-2A BR112016014022B1 (pt) | 2013-12-17 | 2014-12-17 | Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, usos do anticorpo biespecífico e kit |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
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BR122021025085-5A BR122021025085B1 (pt) | 2013-12-17 | 2014-12-17 | Anticorpo anti-cd3, célula hospedeira procariótica, método de produção do anticorpo biespecífico, imunoconjugado, composição, uso do anticorpo biespecífico e kit |
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