AR036114A1 - Tetrahidroimidazol[1,2-a]pirazinas y tetrahidrotriazol[4,3-a]pirazinas como inhibidores de la dipeptidil peptidasa utiles para el tratamiento o la prevencion de la diabetes - Google Patents

Tetrahidroimidazol[1,2-a]pirazinas y tetrahidrotriazol[4,3-a]pirazinas como inhibidores de la dipeptidil peptidasa utiles para el tratamiento o la prevencion de la diabetes

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Publication number
AR036114A1
AR036114A1 ARP020102412A ARP020102412A AR036114A1 AR 036114 A1 AR036114 A1 AR 036114A1 AR P020102412 A ARP020102412 A AR P020102412A AR P020102412 A ARP020102412 A AR P020102412A AR 036114 A1 AR036114 A1 AR 036114A1
Authority
AR
Argentina
Prior art keywords
alkyl
substituted
unsubstituted
branched
linear
Prior art date
Application number
ARP020102412A
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English (en)
Spanish (es)
Original Assignee
Merck & Co Inc
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23172273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR036114(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of AR036114A1 publication Critical patent/AR036114A1/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
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    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
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  • Hematology (AREA)
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  • Cardiology (AREA)
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ARP020102412A 2001-07-06 2002-06-26 Tetrahidroimidazol[1,2-a]pirazinas y tetrahidrotriazol[4,3-a]pirazinas como inhibidores de la dipeptidil peptidasa utiles para el tratamiento o la prevencion de la diabetes AR036114A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30347401P 2001-07-06 2001-07-06

Publications (1)

Publication Number Publication Date
AR036114A1 true AR036114A1 (es) 2004-08-11

Family

ID=23172273

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102412A AR036114A1 (es) 2001-07-06 2002-06-26 Tetrahidroimidazol[1,2-a]pirazinas y tetrahidrotriazol[4,3-a]pirazinas como inhibidores de la dipeptidil peptidasa utiles para el tratamiento o la prevencion de la diabetes

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EP (4) EP1412357B1 (US08124317-20120228-C00026.png)
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CN (2) CN1861077A (US08124317-20120228-C00026.png)
AR (1) AR036114A1 (US08124317-20120228-C00026.png)
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FR07C0041I2 (fr) 2016-09-30
BG108493A (en) 2005-04-30
CN1290848C (zh) 2006-12-20
ATE471148T1 (de) 2010-07-15
HUS0700005I1 (hu) 2022-01-28
US20170348309A1 (en) 2017-12-07
GEP20053734B (en) 2006-01-10
ME00439B (me) 2011-12-20
KR100606871B1 (ko) 2006-08-01
US6699871B2 (en) 2004-03-02
EA200400153A1 (ru) 2004-06-24
EP1412357B1 (en) 2006-03-22
DE60210093T2 (de) 2006-11-23
CY2008014I2 (el) 2009-11-04
HU225695B1 (hu) 2007-06-28
IL159109A (en) 2007-06-03
US20130217695A1 (en) 2013-08-22
RS50737B (sr) 2010-08-31
LTC1412357I2 (lt) 2021-01-11
US20200206221A1 (en) 2020-07-02
US8440668B2 (en) 2013-05-14
ZA200309294B (en) 2004-07-22
KR20040010842A (ko) 2004-01-31
GEP20063734B (en) 2006-01-10
DE122008000046I1 (de) 2009-02-05
CA2450740C (en) 2006-02-14
IS7062A (is) 2003-11-28

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