AR043430A1 - Derivados de diarilcicloalquilo, procesos para su preparacion y su uso como agentes farmaceuticos - Google Patents
Derivados de diarilcicloalquilo, procesos para su preparacion y su uso como agentes farmaceuticosInfo
- Publication number
- AR043430A1 AR043430A1 ARP040100633A ARP040100633A AR043430A1 AR 043430 A1 AR043430 A1 AR 043430A1 AR P040100633 A ARP040100633 A AR P040100633A AR P040100633 A ARP040100633 A AR P040100633A AR 043430 A1 AR043430 A1 AR 043430A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- ring
- case
- phenyl
- alkanediyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Los compuestos son adecuados para el tratamiento y/o prevención de trastornos del metabolismo de ácidos grasos y trastornos de la utilización de la glucosa, así como de trastornos en los que está implicada la resistencia a la insulina. Reivindicación 1: Un compuesto de fórmula (1), en la que: El anillo A es cicloalcanodiilo (C3-8) o cicloalquenodiilo (C3-8), donde en los anillos cicloalcanodiilo o cicloalquenodiilo uno o más átomos de carbono pueden estar reemplazados con átomos de oxígeno; El anillo B a) fenilo; o b) un anillo heteroaromático de 5 a 123 miembros que puede contener de uno a cuatro heteroátomos seleccionados entre el grupo compuestos por N, O y S, y un anillo aromático de 8 a 14 miembros o cicloalquilo (C3-8); R1 es a) en el caso del anillo B = a): SCF3, OCF2-CHF2, O-fenilo, O-alquil(C1-6)-O-alquilo(C1-3); b) en el caso del anillo B = b): H, F, Cl, Br, OH, NO2, CF3, OCF3, OCF2-CF3, SCF3, OCF2-CGF2, O-fenilo, alquilo (C1-6), O-alquilo (C1-6), O-alquil(C1-6)-O-alquilo(C1-3); c) en el caso del anillo B = a) y R4 = fenilo: alquilo (C1-6) o O-alquilo (C1-6); R2 es H o CF3; R4 es a) en el caso del anillo B = a): fenilo; b) en el caso del anillo B = b): H, F, Cl, Br, OH, NO2, CF3, OCF3, alquilo (C1-6), O-alquilo (C1-6); c) en el caso del anillo B = a) y R1 = a): alquilo (C1-6); R5 es H, Cl, Br, OH, NO2, CF3, OCF3, alquilo (C1-6), O-alquilo (C1-6); R3 es H o alquilo (C1-6); X es alcanodiilo (C1-6), donde en el grupo alcanodiilo, uno o más átomos de carbono pueden reemplazarse por átomos de oxígeno; Y es alcanodiilo (C1-6), donde en el grupo alcanodiilo, uno o más átomos de carbono pueden reemplazarse por átomos de oxígeno; y sus sales fisiológicamente aceptables.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10308353A DE10308353A1 (de) | 2003-02-27 | 2003-02-27 | Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR043430A1 true AR043430A1 (es) | 2005-07-27 |
Family
ID=32920627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040100633A AR043430A1 (es) | 2003-02-27 | 2004-02-27 | Derivados de diarilcicloalquilo, procesos para su preparacion y su uso como agentes farmaceuticos |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7160911B2 (es) |
| EP (1) | EP1599454B1 (es) |
| JP (1) | JP2006519197A (es) |
| KR (1) | KR20050106053A (es) |
| CN (1) | CN100439346C (es) |
| AR (1) | AR043430A1 (es) |
| AU (1) | AU2004216520B2 (es) |
| BR (1) | BRPI0407901A (es) |
| CA (1) | CA2516573A1 (es) |
| CO (1) | CO5690579A2 (es) |
| DE (1) | DE10308353A1 (es) |
| HR (1) | HRP20050740A2 (es) |
| IL (1) | IL170313A (es) |
| MA (1) | MA27741A1 (es) |
| MX (1) | MXPA05008993A (es) |
| NO (1) | NO20054382L (es) |
| PL (1) | PL377741A1 (es) |
| RU (1) | RU2005129999A (es) |
| TW (1) | TW200505880A (es) |
| WO (1) | WO2004075815A2 (es) |
| ZA (1) | ZA200505763B (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7399777B2 (en) * | 2001-08-31 | 2008-07-15 | Sanofi-Aventis Deutschland Gmbh | Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmceuticals |
| ATE347890T1 (de) * | 2001-08-31 | 2007-01-15 | Sanofi Aventis Deutschland | Diarylcycloalkylderivate, verfahren zu ihrer herstellung und ihre verwendung als ppar- aktivatoren |
| JPWO2006016637A1 (ja) | 2004-08-11 | 2008-05-01 | 杏林製薬株式会社 | 新規環状アミノ安息香酸誘導体 |
| DE102004040736B4 (de) * | 2004-08-23 | 2007-01-11 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Diarylcycloalkylderivaten |
| DE102004060227B3 (de) | 2004-12-15 | 2006-07-20 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Oxazolen durch Kondensation von aromatischen Aldehyden mit α-Ketoximen zu N-Oxiden und nachfolgende Reaktion mit aktivierten Säurederivaten |
| EP1862464A4 (en) * | 2005-03-23 | 2010-08-25 | Kyorin Seiyaku Kk | NEW CYCLIC AMINOPHENYL ALKANIC ACID DERIVATIVE |
| MY147393A (en) | 2005-09-14 | 2012-11-30 | Takeda Pharmaceutical | Administration of dipeptidyl peptidase inhibitors |
| CN102675221A (zh) | 2005-09-16 | 2012-09-19 | 武田药品工业株式会社 | 用于制备嘧啶二酮衍生物的方法中的中间体 |
| CA2624102A1 (en) | 2005-09-29 | 2007-04-12 | Sanofi-Aventis | Phenyl- and pyridinyl- 1, 2 , 4 - oxadiazolone derivatives, processes for their preparation and their use as pharmaceuticals |
| WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
| US8153644B2 (en) * | 2007-05-22 | 2012-04-10 | Madrigal Pharmaceuticals, Inc. | Diacylglycerol acyltransferase inhibitors |
| US8115011B2 (en) * | 2007-05-22 | 2012-02-14 | Madrigal Pharmaceuticals, Inc. | Diacylglycerol acyltransferase inhibitors |
| US8211884B2 (en) * | 2008-08-06 | 2012-07-03 | Madrigal Pharmaceuticals, Inc. | Diacylglycerol acyltransferase inhibitors |
| US8324385B2 (en) * | 2008-10-30 | 2012-12-04 | Madrigal Pharmaceuticals, Inc. | Diacylglycerol acyltransferase inhibitors |
| WO2010077861A1 (en) * | 2008-12-17 | 2010-07-08 | Via Pharmaceuticals, Inc | Inhibitors of diacylglycerol aclytransferase |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2663336B1 (fr) | 1990-06-18 | 1992-09-04 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| AU658955B2 (en) * | 1992-01-28 | 1995-05-04 | Sumitomo Chemical Company, Limited | An oxazoline derivative, its production and its use |
| IL108634A0 (en) | 1993-02-15 | 1994-05-30 | Wellcome Found | Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them |
| IL108633A (en) | 1993-02-15 | 1998-07-15 | Wellcome Found | History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them |
| JP3144624B2 (ja) | 1995-06-02 | 2001-03-12 | 杏林製薬株式会社 | Ｎ−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
| HUP9902056A3 (en) | 1996-01-17 | 2002-02-28 | Novo Nordisk As | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use |
| JP3149958B2 (ja) | 1996-08-30 | 2001-03-26 | ノボ ノルディスク アクティーゼルスカブ | Ｇｌｐ―１誘導体 |
| TW492957B (en) | 1996-11-07 | 2002-07-01 | Novartis Ag | N-substituted 2-cyanopyrrolidnes |
| PT958296E (pt) | 1996-12-31 | 2003-11-28 | Reddys Lab Ltd Dr | Compostos heterociclicos processo para a sua preparacao composicoes farmaceuticas contendo-os e sua utilizacao no tratamento da diabetes e doencas relacionadas |
| AUPO713297A0 (en) * | 1997-06-02 | 1997-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Oxazole compound |
| DE19726167B4 (de) | 1997-06-20 | 2008-01-24 | Sanofi-Aventis Deutschland Gmbh | Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung |
| WO1999003861A1 (en) | 1997-07-16 | 1999-01-28 | Novo Nordisk A/S | Fused 1,2,4-thiadiazine derivatives, their preparation and use |
| CO4970713A1 (es) | 1997-09-19 | 2000-11-07 | Sanofi Synthelabo | Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen |
| EP1067109B1 (en) * | 1998-03-10 | 2009-12-09 | Ono Pharmaceutical Co., Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
| DE19823831A1 (de) | 1998-05-28 | 1999-12-02 | Probiodrug Ges Fuer Arzneim | Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen |
| MA26634A1 (fr) | 1998-06-04 | 2004-12-20 | Astra Ab | Nouveaux derives de l'acide 3-aryl propionique et analogues |
| SE9801992D0 (sv) | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl-2-hydroxypropionic acid derivative I |
| US6221897B1 (en) | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
| DE19828113A1 (de) | 1998-06-24 | 2000-01-05 | Probiodrug Ges Fuer Arzneim | Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV |
| DE19828114A1 (de) | 1998-06-24 | 2000-01-27 | Probiodrug Ges Fuer Arzneim | Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV |
| AU4394799A (en) * | 1998-07-01 | 2000-01-24 | Takeda Chemical Industries Ltd. | Retinoid-associated receptor regulators |
| DE19845405C2 (de) | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
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| GB9900416D0 (en) | 1999-01-08 | 1999-02-24 | Alizyme Therapeutics Ltd | Inhibitors |
| DE19916108C1 (de) | 1999-04-09 | 2001-01-11 | Aventis Pharma Gmbh | Mit Zuckerresten substituierte 1,4-Benzothiazepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
| JP2002542245A (ja) | 1999-04-16 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | 置換イミダゾール、それらの製造および使用 |
| JP4598278B2 (ja) | 1999-04-28 | 2010-12-15 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Ｐｐａｒ受容体リガンドとしてのジアリール酸誘導体 |
| SK15522001A3 (sk) * | 1999-04-28 | 2002-06-04 | Aventis Pharma Deutschland Gmbh | Deriváty kyselín s tromi arylovými zvyškami ako ligandy receptorov PPAR a farmaceutické kompozície, ktoré ich obsahujú |
| CA2371271A1 (en) | 1999-04-30 | 2000-11-09 | Neurogen Corporation | 9h-pyrimido[4,5-b]indole derivatives: crf1 specific ligands |
| GB9911863D0 (en) | 1999-05-21 | 1999-07-21 | Knoll Ag | Therapeutic agents |
| EP1194146B1 (en) | 1999-06-18 | 2006-07-19 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
| AU5784000A (en) | 1999-07-09 | 2001-01-30 | Cohesion Technologies, Inc. | Ecarin polypeptides, polynucleotides encoding ecarin, and methods for use thereof |
| AU768310B2 (en) | 1999-07-29 | 2003-12-04 | Eli Lilly And Company | Benzofurylpiperazines and benzofurylhomopiperazines: serotonin agonists |
| AU774071B2 (en) | 1999-09-01 | 2004-06-17 | Sanofi-Aventis Deutschland Gmbh | Sulfonyl carboxamide derivatives, method for their production and their use as medicaments |
| WO2001017994A1 (en) * | 1999-09-08 | 2001-03-15 | Glaxo Group Limited | Oxazole ppar antagonists |
| US6414002B1 (en) * | 1999-09-22 | 2002-07-02 | Bristol-Myers Squibb Company | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method |
| TWI260321B (en) | 1999-09-22 | 2006-08-21 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method |
| SE9904413D0 (sv) | 1999-12-03 | 1999-12-03 | Astra Ab | Comminuted form |
| DE60008921T2 (de) | 1999-12-03 | 2005-01-20 | Astrazeneca Ab | Kristalline form von (s)-2-ethoxy-3-4-(2-4-methansulfonyloxyphenyl-ethoxy)phenyl]propansäure |
| WO2001072290A2 (en) | 2000-03-31 | 2001-10-04 | Probiodrug Ag | Method for the improvement of islet signaling in diabetes mellitus and for its prevention |
| EP1277745A4 (en) | 2000-04-25 | 2004-09-15 | Kyorin Seiyaku Kk | NEW STABLE CRYSTALS OF THIAZOLIDINDION DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF |
| ATE369337T1 (de) | 2000-04-28 | 2007-08-15 | Asahi Kasei Pharma Corp | Neue bizyklische verbindungen |
| CA2408486A1 (en) | 2000-05-11 | 2001-11-15 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline analogs useful as growth hormone secretagogues |
| WO2001091752A1 (en) | 2000-05-30 | 2001-12-06 | Merck & Co., Inc. | Melanocortin receptor agonists |
| ES2215902T3 (es) | 2000-06-09 | 2004-10-16 | Aventis Pharma Deutschland Gmbh | Derivados de acil-fenil-ureas, procedimiento para su preparacion y su utilizacion como medicamentos. |
| EP1182251A1 (en) * | 2000-08-11 | 2002-02-27 | Yissum Research Development Company of the Hebrew University of Jerusalem | Methods for identifying compounds that inhibit ubiquitin-mediated proteolysis of IkB |
| TWI243162B (en) | 2000-11-10 | 2005-11-11 | Taisho Pharmaceutical Co Ltd | Cyanopyrrolidine derivatives |
| BR0116325A (pt) | 2000-12-21 | 2003-10-14 | Aventis Pharma Gmbh | 1,2-difenilazetidinonas, processos para a sua preparação, medicamentos contendo estes compostos e sua aplicação para o tratamento de distúrbios do metabolismo de lipìdios |
| KR100718906B1 (ko) * | 2000-12-25 | 2007-05-18 | 오노 야꾸힝 고교 가부시키가이샤 | 디히드로나프탈렌 유도체 화합물 및 이 화합물을 유효성분으로 하는 약제 |
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| DE10142734A1 (de) * | 2001-08-31 | 2003-03-27 | Aventis Pharma Gmbh | Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| ATE347890T1 (de) * | 2001-08-31 | 2007-01-15 | Sanofi Aventis Deutschland | Diarylcycloalkylderivate, verfahren zu ihrer herstellung und ihre verwendung als ppar- aktivatoren |
| DE10215908B4 (de) | 2002-04-11 | 2005-08-18 | Aventis Pharma Deutschland Gmbh | Acyl-3-carboxyphenyl-harnstoffderivate und deren Verwendung als Arzneimittel |
| DE10215907A1 (de) | 2002-04-11 | 2003-11-06 | Aventis Pharma Gmbh | Acyl-4-carboxyphenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung |
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| DE10231370B4 (de) | 2002-07-11 | 2006-04-06 | Sanofi-Aventis Deutschland Gmbh | Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel |
| DE10258007B4 (de) | 2002-12-12 | 2006-02-09 | Sanofi-Aventis Deutschland Gmbh | Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel |
| DE10258008B4 (de) | 2002-12-12 | 2006-02-02 | Sanofi-Aventis Deutschland Gmbh | Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel |
| DE10308351A1 (de) * | 2003-02-27 | 2004-11-25 | Aventis Pharma Deutschland Gmbh | 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US7094795B2 (en) * | 2003-02-27 | 2006-08-22 | Sanofi-Aventis Deutschland Gmbh | Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives |
| US7148246B2 (en) * | 2003-02-27 | 2006-12-12 | Sanofi-Aventis Deutschland Gmbh | Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals |
| DE10308355A1 (de) * | 2003-02-27 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
-
2003
- 2003-02-27 DE DE10308353A patent/DE10308353A1/de not_active Withdrawn
-
2004
- 2004-02-19 PL PL377741A patent/PL377741A1/pl not_active Application Discontinuation
- 2004-02-19 JP JP2006501890A patent/JP2006519197A/ja active Pending
- 2004-02-19 KR KR1020057016020A patent/KR20050106053A/ko not_active Application Discontinuation
- 2004-02-19 CN CNB2004800054472A patent/CN100439346C/zh not_active Expired - Fee Related
- 2004-02-19 EP EP04712502A patent/EP1599454B1/de not_active Expired - Lifetime
- 2004-02-19 AU AU2004216520A patent/AU2004216520B2/en not_active Ceased
- 2004-02-19 WO PCT/EP2004/001584 patent/WO2004075815A2/de active Application Filing
- 2004-02-19 CA CA002516573A patent/CA2516573A1/en not_active Abandoned
- 2004-02-19 RU RU2005129999/04A patent/RU2005129999A/ru not_active Application Discontinuation
- 2004-02-19 MX MXPA05008993A patent/MXPA05008993A/es active IP Right Grant
- 2004-02-19 BR BRPI0407901-9A patent/BRPI0407901A/pt not_active IP Right Cessation
- 2004-02-25 TW TW093104700A patent/TW200505880A/zh unknown
- 2004-02-27 AR ARP040100633A patent/AR043430A1/es not_active Application Discontinuation
- 2004-02-27 US US10/789,019 patent/US7160911B2/en not_active Expired - Lifetime
-
2005
- 2005-07-19 ZA ZA200505763A patent/ZA200505763B/en unknown
- 2005-08-16 IL IL170313A patent/IL170313A/en not_active IP Right Cessation
- 2005-08-26 HR HR20050740A patent/HRP20050740A2/xx not_active Application Discontinuation
- 2005-08-26 MA MA28464A patent/MA27741A1/fr unknown
- 2005-08-26 CO CO05085505A patent/CO5690579A2/es not_active Application Discontinuation
- 2005-09-21 NO NO20054382A patent/NO20054382L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7160911B2 (en) | 2007-01-09 |
| AU2004216520B2 (en) | 2010-01-07 |
| US20040204462A1 (en) | 2004-10-14 |
| IL170313A (en) | 2010-11-30 |
| HRP20050740A2 (en) | 2006-08-31 |
| PL377741A1 (pl) | 2006-02-20 |
| WO2004075815A2 (de) | 2004-09-10 |
| CO5690579A2 (es) | 2006-10-31 |
| CA2516573A1 (en) | 2004-09-10 |
| NO20054382L (no) | 2005-09-21 |
| EP1599454B1 (de) | 2012-12-26 |
| ZA200505763B (en) | 2006-05-31 |
| RU2005129999A (ru) | 2006-03-27 |
| KR20050106053A (ko) | 2005-11-08 |
| AU2004216520A1 (en) | 2004-09-10 |
| MA27741A1 (fr) | 2006-02-01 |
| BRPI0407901A (pt) | 2006-02-14 |
| CN1753880A (zh) | 2006-03-29 |
| JP2006519197A (ja) | 2006-08-24 |
| MXPA05008993A (es) | 2005-10-18 |
| DE10308353A1 (de) | 2004-12-02 |
| TW200505880A (en) | 2005-02-16 |
| EP1599454A2 (de) | 2005-11-30 |
| WO2004075815A3 (de) | 2004-12-29 |
| CN100439346C (zh) | 2008-12-03 |
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