SE9904413D0 - Comminuted form - Google Patents
Comminuted formInfo
- Publication number
- SE9904413D0 SE9904413D0 SE9904413A SE9904413A SE9904413D0 SE 9904413 D0 SE9904413 D0 SE 9904413D0 SE 9904413 A SE9904413 A SE 9904413A SE 9904413 A SE9904413 A SE 9904413A SE 9904413 D0 SE9904413 D0 SE 9904413D0
- Authority
- SE
- Sweden
- Prior art keywords
- compound
- pharmaceutically acceptable
- particle size
- acceptable salt
- reduced particle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
Priority Applications (34)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9904413A SE9904413D0 (sv) | 1999-12-03 | 1999-12-03 | Comminuted form |
CA002392029A CA2392029A1 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl}ethoxy)phenyl] propanoic acid |
ES00983616T ES2208444T3 (es) | 1999-12-03 | 2000-11-29 | Forma pulverizada de acido (s)-2-etoxi-3-(4-(2-(4- metanosulfoniloxifenil)etoxi)fenil)propanoico. |
HU0203692A HUP0203692A3 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy-3-{4-[2-(4-/methanesulfonyloxy/-phenyl)-ethoxy]-phenyl}-propanoic acid and pharmaceutical compoisitions containing them and their use |
CN008163839A CN1216859C (zh) | 1999-12-03 | 2000-11-29 | (s)-2-乙氧基-3-[4-(2-{4-甲磺酰基氧基苯基}乙氧基)苯基]丙酸的粉碎形式 |
DE60005710T DE60005710T2 (de) | 1999-12-03 | 2000-11-29 | Feinteilige form von (s)-2-ethoxy -3- 4-(2- 4-methansulfonyloxyphenyl ethoxy)phenyl]propansäure |
SK766-2002A SK7662002A3 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy -3-[4-(2-{4- methanesulfonyloxyphenyl} ethoxy) phenyl] propanoic acid |
US10/148,825 US7084177B2 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of(S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl}ethoxy)phenyl] propanoic acid |
PL00355372A PL355372A1 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy -3-[4-(2- {4-methanesulfonyloxyphenyl} ethoxy) phenyl] propanoic acid |
CZ20021839A CZ20021839A3 (cs) | 1999-12-03 | 2000-11-29 | Rozmělněná forma (S)-2-ethoxy-3-(4-(2-(4-methansulfonyloxyfenyl)ethoxy)fenyl)propanové kyseliny |
EEP200200284A EE200200284A (et) | 1999-12-03 | 2000-11-29 | (S)-2-etoksü-3-[4-(2-{4-metaansulfonüüloksüfenüül}etoksü)fenüül]propaanhappe peenestatud vorm |
BR0016135-7A BR0016135A (pt) | 1999-12-03 | 2000-11-29 | Forma de tamanho de partìcula reduzido, uso de uma substância, composição farmacêutica, métodos para o tratamento ou a profilaxia de condições associadas com reduzida sensibilidade à insulina e de deslipidemia, diabetes melito do tipo ii, hiperglicemia, hiperinsulinemia, hipertensão arterial e/ou obesidade abdominal e processo para a preparação de um composto |
MXPA02005165A MXPA02005165A (es) | 1999-12-03 | 2000-11-29 | Forma pulverizada de acido [(s)- 2-etoxi -3-[4 -(2-[4- metansulfoniloxifenil) etoxi)fenil ]propanoico]. |
PCT/SE2000/002381 WO2001040169A1 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy -3-[4-(2- {4-methanesulfonyloxyphenyl} ethoxy) phenyl] propanoic acid |
JP2001541856A JP2003515580A (ja) | 1999-12-03 | 2000-11-29 | (s)−2−エトキシ−3−〔4−(2−[4−メタンスルホニルオキシフェニル]エトキシ)フェニル〕プロパン酸の微粉砕形 |
KR1020027007058A KR20020067538A (ko) | 1999-12-03 | 2000-11-29 | 분쇄형(s)-2-에톡시-3-[4-(2-{4-메탄설포닐옥시페닐}에톡시)페닐]프로판산 |
AU20348/01A AU766036B2 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (S)-2-ethoxy -3-(4-(2- (4-methanesulfonyloxyphenyl) ethoxy) phenyl) propanoic acid |
PT00983616T PT1237854E (pt) | 1999-12-03 | 2000-11-29 | Forma pulverizada do acido (s)-2-etoxi-3-¬4-(2-{4- metanossulfoniloxifenil}etoxi)fenil| propanoico |
IL14951600A IL149516A0 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl} ethoxy) phenyl] propanoic acid |
DK00983616T DK1237854T3 (da) | 1999-12-03 | 2000-11-29 | Pulveriseret form af (S)-2-ethoxy-3-[4-(2-(4-methan sulfonyloxyphenyl)ethoxy)phenyl]propanonsyre |
EP00983616A EP1237854B1 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy -3- 4-(2- 4-methanesulfonyloxyphenyl ethoxy) phenyl] propanoic acid |
RU2002113169/04A RU2248966C2 (ru) | 1999-12-03 | 2000-11-29 | Измельченная форма (s)-2-этокси-3-[4-(2-{4-метансульфонилоксифенил}этокси)фенил]пропановой кислоты |
AT00983616T ATE251131T1 (de) | 1999-12-03 | 2000-11-29 | Feinteilige form von (s)-2-ethoxy -3- 4-(2- 4- methansulfonyloxyphenyl ethoxy)phenyl)propansäure |
TR2004/00003T TR200400003T4 (tr) | 1999-12-03 | 2000-11-29 | (S)-2-Ethoxy -3-4-(2-4-Methanesulfonyloxyphenyl ethoxy) propanoic asidin birleştirilmiş hali |
SI200030251T SI1237854T1 (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (s)-2-ethoxy -3- 4-(2- 4-methanesulfonyloxyphenyl ethoxy) phenyl) propanoic acid |
NZ518926A NZ518926A (en) | 1999-12-03 | 2000-11-29 | Comminuted form of (S)-2-ethoxy -3-[4-(2- {4- methanesulfonyloxyphenyl} ethoxy) phenyl] propanoic acid |
UA2002053989A UA73959C2 (en) | 1999-12-03 | 2000-11-29 | Grinded form of (s)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl}ethoxy]phenyl)]propane acid, a method for the preparation thereof and a pharmaceutical composition |
MYPI20005601A MY125099A (en) | 1999-12-03 | 2000-11-30 | Comminuted form of (s)-2-ethoxy-3-4-(2-4-methanesulfonyloxyphenyl ethoxy) penyl] propanoic acid |
CO00091759A CO5271736A1 (es) | 1999-12-03 | 2000-11-30 | Forma triturada |
ARP000106384A AR029456A1 (es) | 1999-12-03 | 2000-12-01 | Forma triturada |
ZA200203797A ZA200203797B (en) | 1999-12-03 | 2002-05-13 | Comminuted form of (S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl} ethoxy)phenyl] propanoic acid. |
IS6399A IS6399A (is) | 1999-12-03 | 2002-05-28 | Mulið form (S)-2-etoxý-3-[4-(2-{4-metansúlfonýloxýfenýl}etoxý)fenýl]própanónsýra |
NO20022591A NO20022591L (no) | 1999-12-03 | 2002-05-31 | Finmalt form av (S)-2-etoksy-3-[4-(2-{4- metansulfonyloksyfenyl}etoksy)fenyl]propansyre |
HK03101434.9A HK1049324B (zh) | 1999-12-03 | 2003-02-26 | (s)-2-乙氧基-3-[4-(2-{4-甲磺酰基氧基苯基}乙氧基)苯基]丙酸的粉碎形式 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9904413A SE9904413D0 (sv) | 1999-12-03 | 1999-12-03 | Comminuted form |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9904413D0 true SE9904413D0 (sv) | 1999-12-03 |
Family
ID=20417978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9904413A SE9904413D0 (sv) | 1999-12-03 | 1999-12-03 | Comminuted form |
Country Status (32)
Country | Link |
---|---|
EP (1) | EP1237854B1 (sv) |
JP (1) | JP2003515580A (sv) |
KR (1) | KR20020067538A (sv) |
CN (1) | CN1216859C (sv) |
AR (1) | AR029456A1 (sv) |
AT (1) | ATE251131T1 (sv) |
AU (1) | AU766036B2 (sv) |
BR (1) | BR0016135A (sv) |
CA (1) | CA2392029A1 (sv) |
CO (1) | CO5271736A1 (sv) |
CZ (1) | CZ20021839A3 (sv) |
DE (1) | DE60005710T2 (sv) |
DK (1) | DK1237854T3 (sv) |
EE (1) | EE200200284A (sv) |
ES (1) | ES2208444T3 (sv) |
HK (1) | HK1049324B (sv) |
HU (1) | HUP0203692A3 (sv) |
IL (1) | IL149516A0 (sv) |
IS (1) | IS6399A (sv) |
MX (1) | MXPA02005165A (sv) |
MY (1) | MY125099A (sv) |
NO (1) | NO20022591L (sv) |
NZ (1) | NZ518926A (sv) |
PL (1) | PL355372A1 (sv) |
PT (1) | PT1237854E (sv) |
RU (1) | RU2248966C2 (sv) |
SE (1) | SE9904413D0 (sv) |
SK (1) | SK7662002A3 (sv) |
TR (1) | TR200400003T4 (sv) |
UA (1) | UA73959C2 (sv) |
WO (1) | WO2001040169A1 (sv) |
ZA (1) | ZA200203797B (sv) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6369067B1 (en) | 1997-10-27 | 2002-04-09 | Dr. Reddy's Research Foundation | Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
AU1198699A (en) | 1997-10-27 | 1999-04-23 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their reparation and pharmaceutical compositions containing them |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
HUP0101110A3 (en) | 1997-10-27 | 2002-06-28 | Reddys Lab Ltd Dr | Bicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
RU2235094C2 (ru) | 1997-10-27 | 2004-08-27 | Др. Редди`З Лабораториз Лимитед | Бета-арил-альфа-оксизамещенные алкилкарбоновые кислоты, способы их получения, промежуточные соединения, способы их получения, фармацевтическая композиция, способы лечения или предупреждения заболеваний на основе новых соединений |
JP2002528535A (ja) | 1998-10-29 | 2002-09-03 | ドクター・レディーズ・リサーチ・ファウンデーション | 新規抗糖尿病剤製造の改良方法 |
US6531596B1 (en) | 1998-10-29 | 2003-03-11 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of new antidiabetic agents |
US6897199B2 (en) | 2001-02-05 | 2005-05-24 | Dr. Reddy's Laboratories Ltd. | Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds |
DE10308351A1 (de) | 2003-02-27 | 2004-11-25 | Aventis Pharma Deutschland Gmbh | 1,3-substituierte Cycloalkylderivate mit sauren, meist heterocyclischen Gruppen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE10308352A1 (de) | 2003-02-27 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Arylcycloalkylderivate mit verzweigten Seitenketten, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
DE10308353A1 (de) | 2003-02-27 | 2004-12-02 | Aventis Pharma Deutschland Gmbh | Diarylcycloalkylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE10308355A1 (de) | 2003-02-27 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Aryl-cycloalkyl substituierte Alkansäurederivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel |
US7148246B2 (en) | 2003-02-27 | 2006-12-12 | Sanofi-Aventis Deutschland Gmbh | Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals |
AU2004293013B2 (en) | 2003-11-19 | 2011-04-28 | Metabasis Therapeutics, Inc. | Novel phosphorus-containing thyromimetics |
EP1586573B1 (en) | 2004-04-01 | 2007-02-07 | Sanofi-Aventis Deutschland GmbH | Oxadiazolones, processes for their preparation and their use as pharmaceuticals |
DE102005026762A1 (de) | 2005-06-09 | 2006-12-21 | Sanofi-Aventis Deutschland Gmbh | Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen |
EP2063890A1 (en) | 2006-09-07 | 2009-06-03 | Nycomed GmbH | Combination treatment for diabetes mellitus |
PL2125711T3 (pl) | 2007-03-08 | 2014-05-30 | Albireo Ab | Pochodne kwasy 3-fenylopropionowego oraz ich zastosowanie w leczeniu nieswoistego zapalenia jelit |
ES2465216T3 (es) | 2007-06-04 | 2014-06-05 | Ben Gurion University Of The Negev Research And Development Authority | Compuestos de triarilo y composiciones que comprenden los mismos |
WO2010093601A1 (en) | 2009-02-10 | 2010-08-19 | Metabasis Therapeutics, Inc. | Novel sulfonic acid-containing thyromimetics, and methods for their use |
CR20160207A (es) | 2013-11-05 | 2016-08-10 | Ben Gurion Univ Of The Negev Res And Dev Authority | Compuestos para el tratamiento de la diabetes y las complicaciones que surgen de la misma enfermedad |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9704873D0 (sv) * | 1997-12-23 | 1997-12-23 | Astra Ab | Sampling apparatus |
MA26634A1 (fr) * | 1998-06-04 | 2004-12-20 | Astra Ab | Nouveaux derives de l'acide 3-aryl propionique et analogues |
-
1999
- 1999-12-03 SE SE9904413A patent/SE9904413D0/sv unknown
-
2000
- 2000-11-29 CN CN008163839A patent/CN1216859C/zh not_active Expired - Fee Related
- 2000-11-29 CA CA002392029A patent/CA2392029A1/en not_active Abandoned
- 2000-11-29 UA UA2002053989A patent/UA73959C2/uk unknown
- 2000-11-29 RU RU2002113169/04A patent/RU2248966C2/ru not_active IP Right Cessation
- 2000-11-29 HU HU0203692A patent/HUP0203692A3/hu unknown
- 2000-11-29 TR TR2004/00003T patent/TR200400003T4/xx unknown
- 2000-11-29 JP JP2001541856A patent/JP2003515580A/ja not_active Withdrawn
- 2000-11-29 DE DE60005710T patent/DE60005710T2/de not_active Expired - Fee Related
- 2000-11-29 DK DK00983616T patent/DK1237854T3/da active
- 2000-11-29 CZ CZ20021839A patent/CZ20021839A3/cs unknown
- 2000-11-29 PL PL00355372A patent/PL355372A1/xx not_active Application Discontinuation
- 2000-11-29 WO PCT/SE2000/002381 patent/WO2001040169A1/en not_active Application Discontinuation
- 2000-11-29 EE EEP200200284A patent/EE200200284A/xx unknown
- 2000-11-29 IL IL14951600A patent/IL149516A0/xx unknown
- 2000-11-29 ES ES00983616T patent/ES2208444T3/es not_active Expired - Lifetime
- 2000-11-29 KR KR1020027007058A patent/KR20020067538A/ko not_active Application Discontinuation
- 2000-11-29 MX MXPA02005165A patent/MXPA02005165A/es active IP Right Grant
- 2000-11-29 PT PT00983616T patent/PT1237854E/pt unknown
- 2000-11-29 AU AU20348/01A patent/AU766036B2/en not_active Ceased
- 2000-11-29 SK SK766-2002A patent/SK7662002A3/sk unknown
- 2000-11-29 BR BR0016135-7A patent/BR0016135A/pt not_active IP Right Cessation
- 2000-11-29 AT AT00983616T patent/ATE251131T1/de not_active IP Right Cessation
- 2000-11-29 NZ NZ518926A patent/NZ518926A/en unknown
- 2000-11-29 EP EP00983616A patent/EP1237854B1/en not_active Expired - Lifetime
- 2000-11-30 MY MYPI20005601A patent/MY125099A/en unknown
- 2000-11-30 CO CO00091759A patent/CO5271736A1/es not_active Application Discontinuation
- 2000-12-01 AR ARP000106384A patent/AR029456A1/es unknown
-
2002
- 2002-05-13 ZA ZA200203797A patent/ZA200203797B/en unknown
- 2002-05-28 IS IS6399A patent/IS6399A/is unknown
- 2002-05-31 NO NO20022591A patent/NO20022591L/no unknown
-
2003
- 2003-02-26 HK HK03101434.9A patent/HK1049324B/zh not_active IP Right Cessation
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