BR0313162A - Composto, processo para preparar o mesmo, e, composição farmacêutica - Google Patents

Composto, processo para preparar o mesmo, e, composição farmacêutica

Info

Publication number
BR0313162A
BR0313162A BR0313162-9A BR0313162A BR0313162A BR 0313162 A BR0313162 A BR 0313162A BR 0313162 A BR0313162 A BR 0313162A BR 0313162 A BR0313162 A BR 0313162A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
preparing same
antiinflammatory activity
macrolide
Prior art date
Application number
BR0313162-9A
Other languages
English (en)
Inventor
Mauro Napoletano
Ermanno Moriggi
Andrea Mereu
Fernando Ornaghi
Gabriele Morazzoni
Roberto Longoni
Carlo Riva
Luciano Pacchetti
Franco Pellacini
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of BR0313162A publication Critical patent/BR0313162A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSTO, PROCESSO PARA PREPARAR O MESMO, E, COMPOSIçãO FARMACêUTICA" . Descreve-se compostos macrolídios dotados de atividade antiinflamatória, e, mais particularmente, derivados de macrolídios não apresentando cladinose na posição 3, com atividade antiinflamatória, sais farmaceuticamente aceitáveis dos mesmos e composições farmacêuticas contendo os mesmos como ingrediente ativo.
BR0313162-9A 2002-08-01 2003-07-29 Composto, processo para preparar o mesmo, e, composição farmacêutica BR0313162A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001726A ITMI20021726A1 (it) 2002-08-01 2002-08-01 Macrolidi ad attivita' antiinfiammatoria.
PCT/EP2003/008448 WO2004013153A2 (en) 2002-08-01 2003-07-29 Macrolide compounds endowed with antiinflammatory activity

Publications (1)

Publication Number Publication Date
BR0313162A true BR0313162A (pt) 2005-07-05

Family

ID=31198615

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0313162-9A BR0313162A (pt) 2002-08-01 2003-07-29 Composto, processo para preparar o mesmo, e, composição farmacêutica

Country Status (18)

Country Link
US (2) US7488811B2 (pt)
EP (2) EP1529053B1 (pt)
JP (1) JP4589110B2 (pt)
KR (1) KR101051369B1 (pt)
CN (1) CN100335491C (pt)
AT (1) ATE509938T1 (pt)
AU (1) AU2003269861B2 (pt)
BR (1) BR0313162A (pt)
CA (1) CA2493995C (pt)
CO (1) CO5720000A2 (pt)
ES (1) ES2364647T3 (pt)
HR (1) HRP20050195B1 (pt)
IL (1) IL166527A0 (pt)
IT (1) ITMI20021726A1 (pt)
NZ (1) NZ537992A (pt)
PT (1) PT1529053E (pt)
RU (1) RU2330856C2 (pt)
WO (1) WO2004013153A2 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
PT1532131E (pt) 2002-08-29 2009-02-18 Pfizer Compostos motilidos
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
US7407941B2 (en) 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
ITMI20040124A1 (it) * 2004-01-29 2004-04-29 Zambon Spa Macrolidi ad attivita' antiinfiammatoria
CN1950388A (zh) * 2004-02-27 2007-04-18 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
JP5383037B2 (ja) * 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
US7910559B2 (en) * 2005-01-13 2011-03-22 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Decladinosyl-macrolides with anti-inflammatory activity
US20080249034A1 (en) * 2005-03-21 2008-10-09 Zambon S.P.A. Use of Macrolides for Treating Intestinal Inflammation
WO2007003422A1 (en) * 2005-07-06 2007-01-11 Zambon S.P.A. Crystalline forms of macrolide compounds endowed with antiinflammatory activity
WO2007025089A2 (en) 2005-08-24 2007-03-01 Rib-X Pharmaceutical, Inc. Triazole compounds and methods of making and using the same
US8278281B2 (en) 2005-08-24 2012-10-02 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
SI1937642T1 (sl) 2005-10-19 2015-01-30 Teva Pharmaceutical Industries Ltd. Kristali natrijevega lakvinimoda in postopek za njihovo pripravo
JP2009518396A (ja) * 2005-12-08 2009-05-07 ファイザー・インク エリスロマイシン化合物の３’−ジメチルアミノ基を脱メチルする方法
CN103193840A (zh) 2006-05-01 2013-07-10 大正制药株式会社 大环内酯衍生物
WO2008106204A1 (en) * 2007-02-28 2008-09-04 Rib-X-Pharmaceuticals, Inc. Macrolide compounds and methods of making and using the same
WO2009106419A1 (en) 2008-02-08 2009-09-03 Basilea Pharmaceutica Ag New macrolides and their use
TW200946109A (en) * 2008-05-09 2009-11-16 Enanta Pharm Inc Anti-bacterial activity of 9-hydroxy derivatives 6, 11-bicyclolides
SG172782A1 (en) 2009-01-30 2011-08-29 Glaxo Group Ltd Anti-inflammatory macrolide
WO2010086350A1 (en) 2009-01-30 2010-08-05 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. 9-deoxo- 9a-methyl- 9a- aza- 9a-h0m0erythr0mycin a derivatives for the treatment of neutrophil dominated inflammatory diseases
US8865662B2 (en) 2009-08-13 2014-10-21 Basilea Pharmaceutica Ag Macrolides and their use
WO2011131749A1 (en) 2010-04-23 2011-10-27 Glaxo Group Limited New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases
MX2015005632A (es) 2012-11-07 2016-02-05 Teva Pharma Sales de amina de laquinimod.
CA2901849A1 (en) 2013-03-14 2014-09-25 Teva Pharmaceutical Industries Ltd. Crystals of laquinimod sodium and improved process for the manufacture thereof
US20160031925A1 (en) * 2013-04-10 2016-02-04 Probiotic Pharmaceuticals Aps Azithromycin antimicrobial derivatives with non-antibiotic pharmaceutical effect
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds
EP4051687A4 (en) * 2020-01-08 2022-12-21 Beijing Continent Pharmaceuticals Co., Ltd. MACROLIDE COMPOUND AND USE THEREOF FOR THE TREATMENT OF CHRONIC RESPIRATORY DISEASE

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) * 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US3623784A (en) * 1969-11-05 1971-11-30 Massey Ferguson Ind Ltd Cabinet joint structure
US3725385A (en) 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
US3923784A (en) * 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
US3928387A (en) * 1974-02-04 1975-12-23 Hoffmann La Roche Antibiotic 1745A/X and methods for the production thereof
EP0184921A3 (en) * 1984-12-08 1986-10-29 Beecham Group Plc Erythromycin derivatives
EP0254534A3 (en) 1986-07-24 1991-04-17 William S. Robinson Erythromycin derivatives and compositions and use for inhibiting virus replication and disease
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
WO1992016226A1 (en) 1991-03-19 1992-10-01 Smithkline Beecham Corporation Il-1 inhibitors
KR960700258A (ko) * 1993-01-26 1996-01-19 우에하라 아키라 5-0-데소사미닐에리쓰로노라이드 유도체
US6096715A (en) * 1993-05-07 2000-08-01 City Of Hope Chimeric DNA-RNA catalytic sequences
KR970704455A (ko) 1994-08-12 1997-09-06 우에하라 아끼라 인터류킨 5 생성 억제제(Interleukin 5 Production Inhibitor)
AU3192695A (en) 1994-08-12 1996-03-07 Taisho Pharmaceutical Co., Ltd. Interleukin-5 production inhibitor
IT1276901B1 (it) 1994-12-13 1997-11-03 Zambon Spa Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
FR2735694B1 (fr) 1995-06-20 1997-08-08 Roussel Uclaf Le cladinose a titre de medicament et les compositions pharmaceutiques les renfermant
FR2738571B1 (fr) * 1995-09-11 1997-10-17 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
AU714176B2 (en) * 1995-11-08 1999-12-23 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
FR2745290B1 (fr) * 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
ZA987689B (en) * 1997-09-02 1999-02-24 Abbott Lab 3-descladinose 6-O substituted erythromycin derivatives
PL339575A1 (en) 1997-09-30 2000-12-18 Abbott Lab 3'-n-modified, 6-o-substituted ketolydic derivatives of erythromycin exhibiting antibacterial activity
JPH11236395A (ja) * 1997-12-11 1999-08-31 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
US5892008A (en) * 1997-12-16 1999-04-06 Abbott Laboratories Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives
EP0941998B1 (en) * 1998-03-03 2004-09-01 Pfizer Products Inc. 3,6-ketal macrolide antibiotics
IT1306205B1 (it) 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
DE19910159A1 (de) 1999-02-26 2000-09-14 Rosemarie Heis Spezifische lgY-Eidotterantikörper, ihre Gewinnung und ihre Verwendung
JP2000351793A (ja) * 1999-06-09 2000-12-19 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
JP2001181294A (ja) 1999-12-27 2001-07-03 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US20060043226A1 (en) * 2004-08-24 2006-03-02 Keith Roozeboom Apparatus and method for grinding with staggered cutters
US7096915B2 (en) * 2004-11-05 2006-08-29 Hsiu-Man Yu Chen Tape-roll supporting device

Also Published As

Publication number Publication date
WO2004013153A3 (en) 2004-04-08
JP2005538998A (ja) 2005-12-22
KR20050037567A (ko) 2005-04-22
US20090054357A1 (en) 2009-02-26
CN1678620A (zh) 2005-10-05
WO2004013153A2 (en) 2004-02-12
KR101051369B1 (ko) 2011-07-22
CN100335491C (zh) 2007-09-05
EP1529053B1 (en) 2011-05-18
IL166527A0 (en) 2006-01-15
HRP20050195B1 (hr) 2013-10-25
AU2003269861A1 (en) 2004-02-23
ATE509938T1 (de) 2011-06-15
JP4589110B2 (ja) 2010-12-01
NZ537992A (en) 2007-11-30
US7488811B2 (en) 2009-02-10
AU2003269861B2 (en) 2010-01-21
EP2258708A1 (en) 2010-12-08
ES2364647T3 (es) 2011-09-08
ITMI20021726A1 (it) 2004-02-02
RU2330856C2 (ru) 2008-08-10
EP1529053A2 (en) 2005-05-11
CA2493995C (en) 2011-01-04
PT1529053E (pt) 2011-07-05
HRP20050195A2 (en) 2005-12-31
US20060058246A1 (en) 2006-03-16
US7704960B2 (en) 2010-04-27
CO5720000A2 (es) 2007-01-31
CA2493995A1 (en) 2004-02-12
RU2005105592A (ru) 2005-08-27

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07F Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette]

Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2317 DE 02-06-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.