NO325681B1 - Terapeutiske fremgangsmater og blandinger som inneholder isoflavoner - Google Patents

Terapeutiske fremgangsmater og blandinger som inneholder isoflavoner Download PDF

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Publication number
NO325681B1
NO325681B1 NO19990965A NO990965A NO325681B1 NO 325681 B1 NO325681 B1 NO 325681B1 NO 19990965 A NO19990965 A NO 19990965A NO 990965 A NO990965 A NO 990965A NO 325681 B1 NO325681 B1 NO 325681B1
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Norway
Prior art keywords
cancer
stated
compound
compounds
treatment
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NO19990965A
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English (en)
Norwegian (no)
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NO990965D0 (no
NO990965L (no
Inventor
Graham Edmund Kelly
George Eustace Joannou
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Novogen Res Pty Ltd
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Publication of NO990965D0 publication Critical patent/NO990965D0/no
Publication of NO990965L publication Critical patent/NO990965L/no
Publication of NO325681B1 publication Critical patent/NO325681B1/no

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    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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NO19990965A 1996-08-30 1999-02-26 Terapeutiske fremgangsmater og blandinger som inneholder isoflavoner NO325681B1 (no)

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AUPO2039A AUPO203996A0 (en) 1996-08-30 1996-08-30 Therapeutic uses
PCT/AU1997/000563 WO1998008503A1 (en) 1996-08-30 1997-08-29 Therapeutic methods and compositions involving isoflavones

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NO20075066A NO20075066L (no) 1996-08-30 2007-10-08 Farmasoytisk sammensetning som inneholder isoflavoner
NO20075065A NO20075065L (no) 1996-08-30 2007-10-08 Anvendelse av isoflavonforbindelser til a behandle hjertesykdom

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Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE275959T1 (de) * 1992-05-19 2004-10-15 Graham Edmund Kelly Verwendung von isoflavon phyto-östrogen extrakten von soja oder klee
AUPO203996A0 (en) 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
WO1998048790A1 (en) * 1997-04-28 1998-11-05 Anticancer, Inc. Use of genistein and related compounds to treat certain sex hormone related conditions
EP0979074A4 (en) * 1997-05-01 2003-07-09 Novogen Inc TREATMENT OR PREVENTION CLIMATE ACTION SYMPTOMS AND OSTEOPOROSIS
AUPP112497A0 (en) * 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
US5958946A (en) * 1998-01-20 1999-09-28 Styczynski; Peter Modulation of hair growth
CA2323181A1 (en) * 1998-03-16 1999-09-23 The Procter & Gamble Company Methods for regulating skin appearance
JPH11269066A (ja) * 1998-03-20 1999-10-05 Kao Corp 経口用美白剤及び美白用食品
AUPP260798A0 (en) * 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
EP1082122A4 (en) * 1998-05-27 2003-04-09 Sherwood L Gorbach ISOFLAVONOIDS USEFUL IN THE TREATMENT AND PREVENTION OF MIGRAINE HEADACHE
GB9814620D0 (en) * 1998-07-06 1998-09-02 Karobio Ab Vasculoprotector
US8093293B2 (en) 1998-07-06 2012-01-10 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin conditions
US8106094B2 (en) 1998-07-06 2012-01-31 Johnson & Johnson Consumer Companies, Inc. Compositions and methods for treating skin conditions
FR2781154B1 (fr) * 1998-07-15 2001-09-07 Lafon Labor Composition therapeutique a base d'isoflavonoides destinee a etre utilisee dans le traitement des tumeurs par des agents cytotoxiques
WO2000016759A2 (en) * 1998-09-17 2000-03-30 Guido Schnyder Genistein for the treatment of coronary heart disease and for the prevention of restenosis after percutaneous transluminal coronary angioplasty
US6399655B1 (en) 1998-12-22 2002-06-04 Johns Hopkins University, School Of Medicine Method for the prophylactic treatment of cataracts
AUPP868599A0 (en) * 1999-02-15 1999-03-11 Novogen Research Pty Ltd Production of isoflavone derivatives
BR0009814A (pt) * 1999-04-16 2002-01-08 Astrazeneca Ab Processo para tratar de uma doença associada com o receptor-beta estrogênico
US20040072765A1 (en) * 1999-04-28 2004-04-15 Novogen Research Pty Ltd. Cardiovascular and bone treatment using isoflavones
AUPQ266199A0 (en) * 1999-09-06 1999-09-30 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
US20090233999A1 (en) * 1999-09-06 2009-09-17 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ520300A0 (en) * 2000-01-21 2000-02-17 Novogen Research Pty Ltd Food product and process
EP1132084A1 (en) * 2000-03-06 2001-09-12 Docteur Nature Srl Transdermal device for the slow release of soybean derived vegetable estrogens
WO2001074345A2 (en) * 2000-03-31 2001-10-11 Jonathan Ingram Isoflavones for treatment of obesity
DE60128801T2 (de) * 2000-06-14 2008-06-26 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Isoflavone gegen strahlungsinduzierte Sterblichkeit
US6248790B1 (en) 2000-06-29 2001-06-19 Parker Hughes Institute Treatment of inflammation with 2,4,6-trihydroxy-alpha-rho-methoxyphenylacetophenone, or its pharmaceutically acceptable derivatives
ATE400285T1 (de) 2000-08-16 2008-07-15 Unilever Nv Mischungen von isoflavonen und flavonen
AUPQ968700A0 (en) * 2000-08-28 2000-09-21 Intreat Pty Limited Treatment of urinary incontinence
FR2815033B1 (fr) * 2000-10-06 2003-09-05 Negma Lab Derives de 7-carboxy-flavones, porcede pour leur preparation et leur application en therapeutique
US8431550B2 (en) 2000-10-27 2013-04-30 Johnson & Johnson Consumer Companies, Inc. Topical anti-cancer compositions and methods of use thereof
AUPR255401A0 (en) * 2001-01-16 2001-02-08 Novogen Research Pty Ltd Regulation of lipids and/or bone density and compositions therefor
US7192615B2 (en) 2001-02-28 2007-03-20 J&J Consumer Companies, Inc. Compositions containing legume products
AUPR363301A0 (en) 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
AU2006200292B2 (en) * 2001-03-16 2007-11-22 Novogen Research Pty Ltd Treatment of restenosis
EP1368024A4 (en) * 2001-03-16 2009-03-18 Novogen Res Pty Ltd TREATMENT OF RESTENOSIS
US20050119301A1 (en) * 2001-03-16 2005-06-02 Alan Husband Treatment of restenosis
DE10114305A1 (de) * 2001-03-23 2002-09-26 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen mit einem Gehalt an Isoflavonen und Verwendung von Isoflavonen zur Herstellung kosmetischer und dermatologischer Zubereitungen zur Reduktion des Sebumgehaltes der Haut
US6787151B2 (en) 2001-08-10 2004-09-07 Lipton, Division Of Conopco, Inc. Composition for lowering blood cholesterol
AUPR846401A0 (en) * 2001-10-25 2001-11-15 Novogen Research Pty Ltd 6-Hydroxy isoflavones, derivatives and medicaments involving same
EP1503751A4 (en) * 2002-04-09 2007-08-01 Novogen Res Pty Ltd THERAPEUTIC PROCESSES AND COMPOSITIONS WITH ISOFLAV-3-EN AND ISOFLAVAN STRUCTURES
US8668914B2 (en) * 2002-07-24 2014-03-11 Brigham Young University Use of equol for treating skin diseases
US20050245492A1 (en) * 2004-04-28 2005-11-03 Lephart Edwin D Use of equol for treating skin diseases
JP2006504409A (ja) * 2002-07-24 2006-02-09 チルドレンズ　ホスピタル　メディカル　センター 鏡像異性のエクオールを含有する組成物および製品、およびその製造方法
WO2004039327A2 (en) * 2002-10-29 2004-05-13 Colorado State University Research Foundation Use of equol for treating androgen mediated diseases
AU2003257264B2 (en) * 2002-09-06 2007-09-13 Novogen Research Pty Ltd Repair of DNA mutagenic damage
AU2002951271A0 (en) * 2002-09-06 2002-09-19 Novogen Research Pty Ltd Repair of dna mutagenic damage
AU2003264176B2 (en) * 2002-09-23 2008-12-11 Novogen Research Pty Ltd Skin photoageing and actinic damage treatment
CZ2005181A3 (cs) * 2002-09-23 2005-08-17 Novogen Research Pty Ltd Léčba stárnutí pokožky vlivem světla a aktinického poškození pokožky
AU2002951833A0 (en) 2002-10-02 2002-10-24 Novogen Research Pty Ltd Compositions and therapeutic methods invloving platinum complexes
US8580846B2 (en) 2002-10-29 2013-11-12 Brigham Young University Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders
US20070244075A1 (en) * 2003-11-18 2007-10-18 Novogen Research Pty Ltd Isoflavonoid Prodrugs, Compositons Thereof and Therapeutic Methods Involving Same
NZ546150A (en) * 2003-11-19 2010-04-30 Novogen Res Pty Ltd Radiosensitization using isoflavones
US20050143323A1 (en) * 2003-12-30 2005-06-30 Henley E. C. Isoflavone therapy for treating urinary incontinence
JP2005289817A (ja) * 2004-03-09 2005-10-20 Daicho Kikaku:Kk 抗癌剤
CN100351248C (zh) * 2004-07-05 2007-11-28 南京大学 染料木素衍生物及其制法和用途
ATE532777T1 (de) * 2004-09-21 2011-11-15 Marshall Edwards Inc Substituierte chromanderivate, medikamente und anwendungen in der therapie
WO2006032086A1 (en) 2004-09-21 2006-03-30 Novogen Research Pty Ltd Chroman derivatives, medicaments and use in therapy
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
US20060189543A1 (en) * 2005-02-23 2006-08-24 Rosenbloom Richard A Compositions and methods for the treatment of leukemia
ATE496921T1 (de) * 2005-03-24 2011-02-15 Novogen Res Pty Ltd Isoflavonoiddimere
US7528267B2 (en) 2005-08-01 2009-05-05 Girindus America, Inc. Method for enantioselective hydrogenation of chromenes
EP2982679A1 (en) 2005-10-12 2016-02-10 Idera Pharmaceuticals, Inc. Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response
KR101346504B1 (ko) * 2005-12-06 2013-12-31 오츠카 세이야쿠 가부시키가이샤 에쿠올 함유 대두 배축 발효물 및 그의 제조 방법
AU2007314141A1 (en) * 2006-10-30 2008-05-08 Novogen Research Pty Ltd Prevention and reversal of chemotherapy-induced peripheral neuropathy
US8221803B1 (en) 2007-06-25 2012-07-17 OncoNatural Solutions, Inc. Composition for prostate health
CA2731849C (en) * 2008-07-25 2017-07-11 Emory University Use of 7,8-dihydroxyflavone and derivatives thereof as neuroprotectants and antidepressants
EP3087988A3 (en) * 2008-10-06 2017-03-01 Idera Pharmaceuticals, Inc. Use of inhibitors of toll-like receptors in the prevention and treatment of hypercholesterolemia and hyperlipidemia and diseases related thereto
CA2743661C (en) 2008-11-14 2017-01-03 Heartlink Limited Aryl di-substituted propenone compounds
CN101716135B (zh) * 2010-01-08 2012-11-14 山西医科大学 大豆异黄酮固体分散体栓剂及其制备方法
CN103108633B (zh) 2010-06-09 2016-01-27 爱默蕾大学 TrkB激动剂及其用途
JP6013349B2 (ja) 2010-11-01 2016-10-25 メイ ファーマ, インク.Mei Pharma, Inc. 癌の処置のためのイソフラボノイド化合物および方法
MX340363B (es) 2010-11-19 2016-07-06 Idera Pharmaceuticals Inc Compuestos de oligonucleotidos inmuno-reguladores (iro) que modulan la respuesta inmune basada en receptores tipo toll.
CN102503922A (zh) * 2011-11-07 2012-06-20 吉首大学 黄烷醇（异黄烷醇）类尿素酶抑制剂及其合成和用途
CN103127053B (zh) * 2011-11-22 2014-05-21 沈阳药科大学 6-[2-(二甲氨基)乙氧基]黄酮的医药用途
MX2014009308A (es) * 2012-02-29 2014-10-14 Avon Prod Inc Uso de moduladores de cpt-1 y composiciones de los mismos.
CN102784135B (zh) * 2012-07-05 2014-11-05 西安交通大学 基于雌马酚激活BKCa通道的应用
US9593125B2 (en) 2012-07-27 2017-03-14 Emory University Heterocyclic flavone derivatives, compositions, and methods related thereto
CN102846595B (zh) * 2012-09-21 2013-08-28 沈阳药科大学 黄酮类化合物wx-03用于舒张血管平滑肌的用途
CN103030647B (zh) * 2013-01-16 2014-10-29 山东省分析测试中心 一种光甘草定的合成方法
AU2014248041A1 (en) 2013-04-04 2015-10-01 The Administrators Of The Tulane Educational Fund Enhanced osteogenic activity of daidzein analogs on human mesenchymal stem cells
JP6371055B2 (ja) * 2013-12-20 2018-08-08 株式会社ダイセル イソフラバノン類の製造方法
CN105777693A (zh) * 2014-12-22 2016-07-20 王靖林 一种雌马酚的合成方法
ES2877712T3 (es) 2015-02-02 2021-11-17 Mei Pharma Inc Terapias combinadas para su uso en el tratamiento del cáncer de mama
EP3281626B1 (en) * 2015-04-06 2023-08-23 LG Household & Health Care Ltd. Soluble microneedle for delivering poorly-soluble drug
CN105153094B (zh) * 2015-07-08 2017-09-15 江苏省中国科学院植物研究所 碱蓬黄酮c及其制备方法和用途
US20190282540A1 (en) * 2016-04-06 2019-09-19 Noxopharm Limited Targeted drug delivery
AU2017247006B2 (en) * 2016-04-06 2022-05-12 Noxopharm Limited Radiotherapy improvements
US11559510B2 (en) 2016-04-06 2023-01-24 Noxopharm Limited Isoflavonoid composition with improved pharmacokinetics
KR20190016017A (ko) * 2016-04-06 2019-02-15 녹소팜 리미티드 암 치료제의 개선
JP6928000B2 (ja) 2016-04-22 2021-09-01 ノクソファーム リミティド 化学療法の改善
CN108409701B (zh) * 2017-02-10 2020-09-25 山东康迈祺生物科技有限公司 一种二氢大豆苷元的制备方法
CN110590727A (zh) * 2019-09-16 2019-12-20 西安联泽生物科技有限公司 一种雌马酚的制备方法
EP4125870A1 (en) 2020-03-30 2023-02-08 Noxopharm Limited Methods for the treatment of inflammation associated with infection

Family Cites Families (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US35074A (en) * 1862-04-29 Improvement bn snow-plows for railroads
US498631A (en) * 1893-05-30 Nut-lock
DE1518002C3 (de) 1965-01-02 1975-01-23 Merck Patent Gmbh, 6100 Darmstadt Isoflavane und Isoflavene und Verfahren zu Ihrer Herstellung sowie diese enthaltende Arzneimittel
DE1543749A1 (de) * 1966-02-16 1969-12-11 Merck Ag E Verfahren zur Herstellung von 3,4-cis-4-Aryl-isoflavanen
JPS54734B2 (xx) 1973-05-14 1979-01-16
US3973608A (en) * 1973-08-01 1976-08-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Microbial production of certain isoflavones
US3886278A (en) * 1973-08-22 1975-05-27 Mead Johnson & Co Ammonium carboxylate sebum inhibition process
US4061779A (en) * 1973-09-11 1977-12-06 Beecham Group Limited Naphthalene derivatives having anti-inflammatory activity
JPS576427B2 (xx) 1974-01-25 1982-02-04
HU168753B (xx) 1974-05-03 1976-07-28
JPS50160483A (xx) 1974-06-19 1975-12-25
GB1495189A (en) 1975-09-12 1977-12-14 Pfizer Ltd 4-oxo-4h-benzopyran derivatives and process for their preparation
DE2643800C2 (de) * 1976-09-29 1986-10-30 Fritz Werner Industrie-Ausrüstungen GmbH, 6222 Geisenheim Verfahren zur Herstellung von Xylose durch enzymatische Hydrolyse von Xylanen
US4264509A (en) * 1977-06-08 1981-04-28 Z-L Limited Partnership Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same
US4157984A (en) * 1977-06-08 1979-06-12 Z-L Limited Antioxidants, antioxidant compositions and methods of preparing and using same
SU907060A1 (ru) * 1979-02-07 1982-02-23 Всесоюзный Научно-Исследовательский Биотехнический Институт Способ получени розового масла
US4366082A (en) * 1979-04-11 1982-12-28 Z-L Limited Partnership Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same
US4390559A (en) 1979-04-11 1983-06-28 Z-L Limited Partnership Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same
JPS5933232A (ja) * 1982-08-19 1984-02-23 Tokiwa Kanpou Seiyaku:Kk マメ科植物からサポニン類およびフラボン類の分離方法
JPS59199630A (ja) 1983-04-26 1984-11-12 Takeda Chem Ind Ltd 卵巣機能低下症治療剤
JPS6048924A (ja) * 1983-08-24 1985-03-16 Takeda Chem Ind Ltd 骨粗鬆症治療剤
JPS6054379A (ja) * 1983-09-05 1985-03-28 Takeda Chem Ind Ltd 新規４ｈ−１−ベンゾピラン−４−オン誘導体，その製法および用途
JPS60132976A (ja) * 1983-12-21 1985-07-16 Takeda Chem Ind Ltd 新規３−フエニル−４ｈ−１−ベンゾピラン−４−オン誘導体
US4484013A (en) * 1983-12-30 1984-11-20 Uop Inc. Process for coproduction of isopropanol and tertiary butyl alcohol
US4839281A (en) * 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
JPS61246124A (ja) 1985-04-24 1986-11-01 Yamanouchi Pharmaceut Co Ltd 制癌剤
JPS61247396A (ja) * 1985-04-24 1986-11-04 Yamanouchi Pharmaceut Co Ltd ゲニステインの製造法
JPS62106016A (ja) * 1985-11-01 1987-05-16 Yamanouchi Pharmaceut Co Ltd 免疫抑制剤
JPS62106017A (ja) * 1985-11-01 1987-05-16 Yamanouchi Pharmaceut Co Ltd 抗腫瘍剤
JPS62126186A (ja) 1985-11-28 1987-06-08 Tsumura Juntendo Inc イソフラボン誘導体含有溶液の製造方法
GB8626344D0 (en) * 1986-11-04 1986-12-03 Zyma Sa Bicyclic compounds
JPS6442427A (en) 1987-08-10 1989-02-14 Tsumura & Co Sialidase inhibitor
JPH0832632B2 (ja) 1988-03-08 1996-03-29 株式会社太田胃散 尿素窒素代謝改善剤
JPH0714927B2 (ja) 1988-04-06 1995-02-22 キッコーマン株式会社 イソフラボン化合物の製造法
US4950475A (en) * 1988-07-19 1990-08-21 Imaginative Research Associates, Inc. Novel film-forming gels with high concentrations of humectants and emollients
JPH0267218A (ja) * 1988-08-31 1990-03-07 Nagakura Seiyaku Kk ウイルス・ゲノム不活化剤
JPH0269165A (ja) 1988-09-02 1990-03-08 Mitsugi Ohashi 癌抑制食品
JPH02124883A (ja) 1988-11-04 1990-05-14 Kitasato Inst:The 抗酸化作用を有するイソフラボン誘導体およびその製造法
JP2753719B2 (ja) 1988-12-15 1998-05-20 日本油脂株式会社 リポソーム製剤の製造法
JPH02193919A (ja) * 1989-01-23 1990-07-31 Kao Corp 皮脂線抑制剤
JPH0347049A (ja) 1989-03-09 1991-02-28 Sanyu:Kk 豆腐廃液ゆからの食品素材及び健康飲料の製造方法
US5153230A (en) 1989-10-06 1992-10-06 Perfective Cosmetics, Inc. Topical skin cream composition
CH679584A5 (xx) 1989-11-10 1992-03-13 Nestle Sa
IT1241079B (it) 1990-03-23 1993-12-29 Chiesi Farma Spa Composizioni farmaceutiche contenenti ipriflavone,procedimento per la loro preparazione e relativo impiego terapeutico
ATE101143T1 (de) * 1990-04-06 1994-02-15 Chinoin Gyogyszer Es Vegyeszet Verbessertes verfahren zur darstellung substituierter isoflavonderivate.
US5489524A (en) * 1991-03-26 1996-02-06 The United States Of America As Represented By The Department Of Health And Human Services Chimeric protein that has a human Rho motif and deoxyribonuclease activity
JP2799254B2 (ja) * 1991-07-11 1998-09-17 三菱電機株式会社 半導体装置の製造方法
JPH0517056A (ja) * 1991-07-12 1993-01-26 Ricoh Co Ltd ロール紙カセツト
GB2261671B (en) * 1991-11-16 1996-07-03 Gb Biotech Gel production from plant matter
JPH05170756A (ja) 1991-12-20 1993-07-09 Kikkoman Corp イソフラボン化合物の製造法
ATE275959T1 (de) * 1992-05-19 2004-10-15 Graham Edmund Kelly Verwendung von isoflavon phyto-östrogen extrakten von soja oder klee
JP3241440B2 (ja) * 1992-07-02 2001-12-25 有限会社野々川商事 化粧料
FR2693724B1 (fr) 1992-07-17 1994-10-07 Lipha Utilisation de composés benzopyraniques ou benzothiopyraniques pour l'induction de l'expression des gènes de la nodulation des bactéries du genre Rhizobium associées aux légumineuses.
JPH0686682A (ja) 1992-07-23 1994-03-29 Kobe Steel Ltd ４’，７，８−トリヒドロキシイソフラボンの製造方法
JPH0640876A (ja) 1992-07-23 1994-02-15 Kobe Steel Ltd 紫外線障害防御外用剤
JPH0640909A (ja) 1992-07-23 1994-02-15 Kobe Steel Ltd スーパーオキシド・ディスムターゼ様活性剤
DE4236237A1 (de) * 1992-10-27 1994-04-28 Behringwerke Ag Prodrugs, ihre Herstellung und Verwendung als Arzneimittel
WO1994023716A1 (en) * 1993-04-16 1994-10-27 Tufts University School Of Medicine Method for treatment of menopausal and premenstrual symptoms
JPH06321752A (ja) 1993-05-07 1994-11-22 Kao Corp 美白剤
US5595970A (en) * 1993-07-16 1997-01-21 Schering Aktiengesellschaft Treatment of climacteric disorders with nitric oxide synthase substrates and/or donors
WO1995010530A1 (en) * 1993-10-12 1995-04-20 Protein Technologies International, Inc. An aglucone isoflavone enriched vegetable protein extract and isolate and process for producing
EP0723536B2 (en) * 1993-10-12 2006-06-14 Archer Daniels Midland Company An aglucone isoflavone enriched vegetable protein whey, and process for producing
US5320949A (en) * 1993-10-12 1994-06-14 Protein Technologies International, Inc. Process for producing aglucone isoflavone enriched vegetable protein fiber
US5589182A (en) * 1993-12-06 1996-12-31 Tashiro; Renki Compositions and method of treating cardio-, cerebro-vascular and alzheimer's diseases and depression
JP3078694B2 (ja) * 1993-12-17 2000-08-21 キッコーマン株式会社 ゲニステインの製造法
IL112061A (en) * 1994-01-13 1999-10-28 Bristol Myers Squibb Co Methods for the preparation of taxanes
US6369103B1 (en) 1994-01-18 2002-04-09 Bristol-Myers Squibb Company Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
IL112639A0 (en) 1994-03-11 1995-05-26 Bristol Myers Squibb Co A pharmaceutical composition containing pravastin
US5506211A (en) * 1994-05-09 1996-04-09 The Uab Research Foundation Genistein for use in inhibiting osteroclasts
US5424331A (en) * 1994-06-10 1995-06-13 Bio-Virus Research Incorporated Pharmaceutical compositions and dietary soybean food products for the prevention of osteoporosis
US5547866A (en) 1994-07-20 1996-08-20 The Regents Of The University Of California Taxane production in haploid-derived cell cultures
DE4432947C2 (de) * 1994-09-16 1998-04-09 New Standard Gmbh Mittel zur Behandlung der Haut und seine Verwendung
AU3689095A (en) * 1994-10-03 1996-04-26 Schouten Industries B.V. Food and health products
US5637598A (en) * 1994-11-18 1997-06-10 Eli Lilly And Company Methods of inhibiting bone loss
US5516528A (en) * 1995-01-13 1996-05-14 Wake Forest University Dietary phytoestrogen in estrogen replacement therapy
US5569459A (en) * 1995-02-15 1996-10-29 Bio-Virus Research Incorporated Pharmaceutical compositions for the management of premenstrual syndrome and alleviation of menopausal disorders
US5523087A (en) 1995-02-15 1996-06-04 Bio-Virus Research Incorporated Pharmaceutical compositions for the treatment of diabetic male sexual dysfunction
US5679806A (en) * 1995-02-24 1997-10-21 Hauser, Inc. Process for the isolation and purification of isoflavones
JPH08283283A (ja) * 1995-04-14 1996-10-29 Kikkoman Corp マロニルイソフラボン配糖体及び該物質からイソフラボン配糖体又はイソフラボンアグリコンを取得する方法
EP0873142A4 (en) * 1995-06-07 2001-08-08 Sugen Inc CONNECTION TESTING TESTS
US5639785A (en) 1995-06-07 1997-06-17 Global Pharma, Ltd. Methods for the treatment of baldness and gray hair using isoflavonoid derivatives
WO1996039832A1 (en) * 1995-06-07 1996-12-19 Kung Patrick C Compounds and methods for promoting hair growth
US5554519A (en) * 1995-08-07 1996-09-10 Fermalogic, Inc. Process of preparing genistein
JPH0967362A (ja) 1995-09-01 1997-03-11 Sankyo Co Ltd ５α−還元酵素阻害剤ビスイソフラボン類
US6261565B1 (en) * 1996-03-13 2001-07-17 Archer Daniels Midland Company Method of preparing and using isoflavones
US5702752A (en) * 1996-03-13 1997-12-30 Archer Daniels Midland Company Production of isoflavone enriched fractions from soy protein extracts
US5821361A (en) 1996-06-11 1998-10-13 Protein Technologies International, Inc. Recovery of isoflavones from soy molasses
JPH1059956A (ja) 1996-08-22 1998-03-03 Kikkoman Corp 新規イソフラボン誘導体及びその製造法
AUPO203996A0 (en) 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US5726034A (en) * 1996-09-06 1998-03-10 Protein Technologies International, Inc. Aglucone isoflavone enriched vegetable protein extract and protein material, and high genistein and daidzein content materials and process for producing the same
US5804234A (en) * 1996-09-13 1998-09-08 Suh; John D. Plant protein for nutritional products and method of making same
US5733926A (en) * 1996-12-13 1998-03-31 Gorbach; Sherwood L. Isoflavonoids for treatment and prevention of alzheimer dementia and reduced cognitive functions
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
EP0979074A4 (en) 1997-05-01 2003-07-09 Novogen Inc TREATMENT OR PREVENTION CLIMATE ACTION SYMPTOMS AND OSTEOPOROSIS
US6060070A (en) 1997-06-11 2000-05-09 Gorbach; Sherwood L. Isoflavonoids for treatment and prevention of aging skin and wrinkles
US5855892A (en) * 1997-09-19 1999-01-05 Potter; Susan M. Method for decreasing LDL-cholesterol concentration and increasing HDL-cholesterol concentration in the blood to reduce the risk of atherosclerosis and vascular disease
US5942539A (en) * 1997-10-03 1999-08-24 Wake Forest University Methods of treating or preventing endometriosis with phytoestrogens
AUPP112497A0 (en) 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
US6004558A (en) 1998-02-25 1999-12-21 Novogen, Inc. Methods for treating cancer with legume plant extracts
US6132795A (en) 1998-03-15 2000-10-17 Protein Technologies International, Inc. Vegetable protein composition containing an isoflavone depleted vegetable protein material with an isoflavone containing material
CA2323181A1 (en) 1998-03-16 1999-09-23 The Procter & Gamble Company Methods for regulating skin appearance
AUPP260798A0 (en) 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
US6544566B1 (en) 1999-04-23 2003-04-08 Protein Technologies International, Inc. Composition containing plant sterol, soy protein and isoflavone for reducing LDL cholesterol

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