NO318741B1 - N-substituerte 2-cyanopyrrolidiner, farmasoytisk sammensetning som innbefatter slike, samt anvendelse derav for a hemme dipeptidyl-peptidase IV. - Google Patents

N-substituerte 2-cyanopyrrolidiner, farmasoytisk sammensetning som innbefatter slike, samt anvendelse derav for a hemme dipeptidyl-peptidase IV. Download PDF

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Publication number
NO318741B1
NO318741B1 NO20012853A NO20012853A NO318741B1 NO 318741 B1 NO318741 B1 NO 318741B1 NO 20012853 A NO20012853 A NO 20012853A NO 20012853 A NO20012853 A NO 20012853A NO 318741 B1 NO318741 B1 NO 318741B1
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NO
Norway
Prior art keywords
amino
adamantyl
pyrrolidine
cyano
acetyl
Prior art date
Application number
NO20012853A
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English (en)
Norwegian (no)
Other versions
NO20012853L (no
NO20012853D0 (no
Inventor
Edwin Bernard Villhauer
Original Assignee
Novartis Ag
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22777194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO318741(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20012853D0 publication Critical patent/NO20012853D0/no
Publication of NO20012853L publication Critical patent/NO20012853L/no
Publication of NO318741B1 publication Critical patent/NO318741B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20012853A 1998-12-10 2001-06-08 N-substituerte 2-cyanopyrrolidiner, farmasoytisk sammensetning som innbefatter slike, samt anvendelse derav for a hemme dipeptidyl-peptidase IV. NO318741B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20906898A 1998-12-10 1998-12-10
PCT/EP1999/009708 WO2000034241A1 (en) 1998-12-10 1999-12-09 N-substituted 2-cyanopyrrolidines

Publications (3)

Publication Number Publication Date
NO20012853D0 NO20012853D0 (no) 2001-06-08
NO20012853L NO20012853L (no) 2001-08-07
NO318741B1 true NO318741B1 (no) 2005-05-02

Family

ID=22777194

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20012853A NO318741B1 (no) 1998-12-10 2001-06-08 N-substituerte 2-cyanopyrrolidiner, farmasoytisk sammensetning som innbefatter slike, samt anvendelse derav for a hemme dipeptidyl-peptidase IV.
NO2008001C NO2008001I1 (no) 1998-12-10 2008-01-25 Vildagliptin og farmasoytisk akseptable salter derav
NO2008004C NO2008004I1 (no) 1998-12-10 2008-05-09 Kombinasjon omfattende vildagliptin eller et farmasoytisk akseptabelt salt derav, og metformin, eller et farmasoytisk akseptabelt salt derav

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO2008001C NO2008001I1 (no) 1998-12-10 2008-01-25 Vildagliptin og farmasoytisk akseptable salter derav
NO2008004C NO2008004I1 (no) 1998-12-10 2008-05-09 Kombinasjon omfattende vildagliptin eller et farmasoytisk akseptabelt salt derav, og metformin, eller et farmasoytisk akseptabelt salt derav

Country Status (34)

Country Link
US (1) US6166063A (cs)
EP (1) EP1137635B1 (cs)
JP (2) JP3681110B2 (cs)
KR (2) KR100509311B1 (cs)
CN (1) CN1160330C (cs)
AR (1) AR023719A1 (cs)
AT (1) ATE307112T1 (cs)
BR (1) BRPI9915985B8 (cs)
CA (1) CA2350609C (cs)
CO (1) CO5150173A1 (cs)
CY (3) CY1105355T1 (cs)
CZ (1) CZ299151B6 (cs)
DE (3) DE69927844T2 (cs)
DK (1) DK1137635T3 (cs)
ES (1) ES2251847T3 (cs)
FR (1) FR08C0005I2 (cs)
HK (1) HK1040394B (cs)
HU (1) HU226769B1 (cs)
ID (1) ID28796A (cs)
IL (2) IL143091A0 (cs)
LU (2) LU91409I2 (cs)
MY (1) MY123244A (cs)
NL (2) NL300333I2 (cs)
NO (3) NO318741B1 (cs)
NZ (1) NZ511935A (cs)
PE (1) PE20001317A1 (cs)
PL (1) PL199443B1 (cs)
RU (1) RU2251544C2 (cs)
SK (1) SK286635B6 (cs)
TR (1) TR200101478T2 (cs)
TW (1) TW509674B (cs)
UY (1) UY25843A1 (cs)
WO (1) WO2000034241A1 (cs)
ZA (1) ZA200104581B (cs)

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