JP6026642B2 - Ａｍｐｋを活性化させるインドールおよびインダゾール化合物 - Google Patents

Ａｍｐｋを活性化させるインドールおよびインダゾール化合物 Download PDF

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JP6026642B2
JP6026642B2 JP2015505038A JP2015505038A JP6026642B2 JP 6026642 B2 JP6026642 B2 JP 6026642B2 JP 2015505038 A JP2015505038 A JP 2015505038A JP 2015505038 A JP2015505038 A JP 2015505038A JP 6026642 B2 JP6026642 B2 JP 6026642B2
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alkyl
alkoxy
hydroxy
independently
halogen
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JP2015512931A5 (enExample
JP2015512931A (ja
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クマー バッタチャリヤ サミット
クマー バッタチャリヤ サミット
オキーフ キャメロン キムバリー
オキーフ キャメロン キムバリー
スコット ダウリング マシュー
スコット ダウリング マシュー
クリストファー エブナー デイヴィッド
クリストファー エブナー デイヴィッド
プラサドヒニ フェルナンド ディリニー
プラサドヒニ フェルナンド ディリニー
ジェームス フィリップスキ− ケヴィン
ジェームス フィリップスキ− ケヴィン
ウェイ−シャン クン ダニエル
ウェイ−シャン クン ダニエル
チェング イン リー エサー
チェング イン リー エサー
クリストファー スミス アーロン
クリストファー スミス アーロン
マイク トゥ メイフア
マイク トゥ メイフア
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ファイザー・インク
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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JP2015505038A 2012-04-10 2013-04-01 Ａｍｐｋを活性化させるインドールおよびインダゾール化合物 Expired - Fee Related JP6026642B2 (ja)

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US201261622129P 2012-04-10 2012-04-10
US61/622,129 2012-04-10
PCT/IB2013/052604 WO2013153479A2 (en) 2012-04-10 2013-04-01 Indole and indazole compounds that activate ampk

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JP2015512931A5 JP2015512931A5 (enExample) 2016-05-26
JP6026642B2 true JP6026642B2 (ja) 2016-11-16

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Cited By (1)

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JP2016510805A (ja) * 2013-03-15 2016-04-11 ファイザー・インク Ａｍｐｋを活性化させるインダゾール化合物

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TWI644899B (zh) 2013-02-04 2018-12-21 健生藥品公司 Ｆｌａｐ調節劑
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WO2016092413A1 (en) * 2014-12-10 2016-06-16 Pfizer Inc. Indole and indazole compounds that activate ampk
WO2016101887A1 (en) * 2014-12-24 2016-06-30 National Institute Of Biological Sciences, Beijing Necrosis inhibitors
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US10570115B2 (en) 2016-09-30 2020-02-25 Vertex Pharmaceuticals Incorporated Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
HRP20201946T1 (hr) 2016-12-09 2021-01-22 Vertex Pharmaceuticals Incorporated Modulator regulatora transmembranske provodljivosti cistične fibroze, farmaceutski sastavi, postupci liječenja, i postupak za dobivanje modulatora
KR102317480B1 (ko) 2017-03-23 2021-10-25 자코바이오 파마슈티칼스 컴퍼니 리미티드 Shp2 억제제로서 유용한 신규한 헤테로환형 유도체
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PH12014502280B1 (en) 2014-12-15
NZ630700A (en) 2015-11-27
CA2869692C (en) 2016-08-02
WO2013153479A3 (en) 2013-12-05
AR090633A1 (es) 2014-11-26
JP2015512931A (ja) 2015-04-30
US20130267493A1 (en) 2013-10-10
CN104245688A (zh) 2014-12-24
AU2013246552A1 (en) 2014-09-25
IN2014DN09200A (enExample) 2015-07-10
EA201491592A1 (ru) 2015-03-31
CO7091185A2 (es) 2014-10-21
ECSP14026271A (es) 2015-11-30
HUE033096T2 (en) 2017-11-28
AP2014007983A0 (en) 2014-10-31
SG11201405571SA (en) 2014-10-30
EP2836490B1 (en) 2017-06-14
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CU20140118A7 (es) 2014-11-27

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