|
US4294842A
(en)
|
1978-07-13 |
1981-10-13 |
Burroughs Wellcome Co. |
Anti-protozoal oxadiazole derivatives
|
|
DE3173083D1
(en)
|
1980-03-22 |
1986-01-16 |
Fbc Ltd |
Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use
|
|
US4602093A
(en)
|
1984-02-08 |
1986-07-22 |
Merck & Co., Inc. |
Novel substituted imidazoles, their preparation and use
|
|
JPS61200544A
(ja)
|
1985-03-04 |
1986-09-05 |
Toyo Ink Mfg Co Ltd |
電子写真感光体
|
|
DE3600390A1
(de)
|
1986-01-09 |
1987-07-16 |
Hoechst Ag |
Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel
|
|
EP0264883A3
(en)
|
1986-10-21 |
1990-04-04 |
Banyu Pharmaceutical Co., Ltd. |
Substituted pyridine derivatives
|
|
JPS63165376A
(ja)
|
1986-12-27 |
1988-07-08 |
Nippon Soda Co Ltd |
オキサ(チア)ジアゾ−ル誘導体その製造方法及び殺ダニ剤
|
|
JPH01108006A
(ja)
|
1987-10-21 |
1989-04-25 |
Nagasaki Pref Gov |
脆性材料の割断加工方法
|
|
JPH01110376A
(ja)
|
1987-10-24 |
1989-04-27 |
Mizuno Corp |
繊維強化プラスチックス製バットの製造方法
|
|
KR910001238B1
(ko)
|
1988-02-26 |
1991-02-26 |
재단법인 한국화학연구소 |
O-아실아미드옥심 유도체
|
|
EP0338372A3
(en)
|
1988-04-22 |
1991-10-09 |
American Cyanamid Company |
Solubilized pro-drugs
|
|
CA1340821C
(en)
|
1988-10-06 |
1999-11-16 |
Nobuyuki Fukazawa |
Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components
|
|
US5180719A
(en)
|
1988-10-24 |
1993-01-19 |
Norwich Eaton Pharmaceuticals, Inc. |
Antimicrobial quinolonyl lactam esters
|
|
GB8900382D0
(en)
|
1989-01-09 |
1989-03-08 |
Janssen Pharmaceutica Nv |
2-aminopyrimidinone derivatives
|
|
DE69025418T2
(de)
|
1989-04-19 |
1996-11-14 |
Otsuka Pharma Co Ltd |
Phenylcarbonsäurederivate mit einem Heterocyclus
|
|
GB8908875D0
(en)
|
1989-04-19 |
1989-06-07 |
Ici Plc |
Fungicides
|
|
JPH0313040A
(ja)
|
1989-06-09 |
1991-01-22 |
Sharp Corp |
コードレス電話機
|
|
KR910009331B1
(ko)
|
1989-10-23 |
1991-11-11 |
재단법인 한국화학연구소 |
디아자비시클로아민 화합물과 그의 제조방법
|
|
KR910009330B1
(ko)
|
1989-10-23 |
1991-11-11 |
재단법인 한국화학연구소 |
항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
|
|
KR910009333B1
(ko)
|
1989-10-23 |
1991-11-11 |
재단법인 한국화학연구소 |
항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
|
|
US5030631A
(en)
|
1989-11-27 |
1991-07-09 |
Schering Corporation |
Tricylclic arylsulfonamides
|
|
US5747502A
(en)
|
1989-12-13 |
1998-05-05 |
Nippon Kayaku Kabushiki Kaisha |
Process for preparing benzo c!phenanthridinium derivatives, novel compounds prepared by said process, and antitumor agents
|
|
JP3036789B2
(ja)
|
1990-06-22 |
2000-04-24 |
三井化学株式会社 |
新規な複素環式化合物及び医薬組成物
|
|
FR2664592B1
(fr)
|
1990-07-10 |
1994-09-02 |
Adir |
Nouveaux derives de la piperidine, de la tetrahydropyridine et de la pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
US5262565A
(en)
|
1990-11-16 |
1993-11-16 |
Eisai Co., Ltd. |
Naphthalene derivatives
|
|
JP2859451B2
(ja)
|
1991-01-11 |
1999-02-17 |
太平洋セメント株式会社 |
N−フルオロピリジニウム塩の製造方法
|
|
DE4121214A1
(de)
|
1991-06-27 |
1993-01-14 |
Bayer Ag |
7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
|
|
JP3038065B2
(ja)
|
1991-11-07 |
2000-05-08 |
太平洋セメント株式会社 |
N−フルオロピリジニウム塩の製造方法
|
|
JPH05196976A
(ja)
|
1991-11-18 |
1993-08-06 |
Toshiba Corp |
有機非線形光学材料
|
|
BR9206810A
(pt)
|
1991-11-25 |
1995-10-31 |
Pfizer |
Derivados de indol
|
|
HU220601B1
(hu)
|
1992-04-30 |
2002-03-28 |
Taiho Pharmaceutical Co. Ltd. |
Fenoxi-alkil-oxazolidin-származékok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények
|
|
DE4232418A1
(de)
|
1992-09-28 |
1994-03-31 |
Bayer Ag |
Verwendung von substituierten 1,2,4-Oxadiazolderivaten zur Bekämpfung von Endoparasiten, neue substituierte 1,2,4-Oxadiazolderivate und Verfahren zu ihrer Herstellung
|
|
JP3130400B2
(ja)
|
1993-01-13 |
2001-01-31 |
信越化学工業株式会社 |
重合体スケール付着防止剤、及びそれを利用する重合体の製造方法
|
|
JPH07164400A
(ja)
|
1993-12-15 |
1995-06-27 |
Nec Corp |
ガラス基板の切断装置
|
|
DE4401108A1
(de)
|
1994-01-17 |
1995-07-20 |
Bayer Ag |
1,2,4-Oxadiazol-Derivate
|
|
US6878715B1
(en)
|
1994-02-18 |
2005-04-12 |
Cell Therapeutics, Inc. |
Therapeutic compounds for inhibiting interleukin-12 signals and method for using same
|
|
IT1274018B
(it)
|
1994-02-23 |
1997-07-14 |
Riace Ets |
Derivati del 3,8-diazabiciclo(3.2.1.)ottano ad attivita' analgesica
|
|
FR2732964B1
(fr)
|
1995-04-14 |
1997-05-16 |
Adir |
Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
|
|
JP3830183B2
(ja)
|
1995-09-29 |
2006-10-04 |
東京応化工業株式会社 |
オキシムスルホネート化合物及びレジスト用酸発生剤
|
|
DE19608316C2
(de)
|
1996-02-22 |
2000-11-09 |
Ivoclar Ag Schaan |
Funktionalisierte bicyclische (Meth)acrylate, Verfahren zu deren Herstellung und deren Verwendung ####
|
|
KR20000075833A
(ko)
|
1997-02-28 |
2000-12-26 |
캔디센트 테크날러지스 코퍼레이션 |
폴리카보네이트-함유 액상 화학배합물 및 폴리카보네이트 막의제조방법
|
|
US6500885B1
(en)
|
1997-02-28 |
2002-12-31 |
Candescent Technologies Corporation |
Polycarbonate-containing liquid chemical formulation and methods for making and using polycarbonate film
|
|
WO1998050364A1
(en)
|
1997-05-03 |
1998-11-12 |
Smithkline Beecham Plc |
Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors
|
|
JPH1110376A
(ja)
|
1997-06-25 |
1999-01-19 |
Souei Tsusho Kk |
割断加工方法
|
|
WO1999001442A1
(en)
|
1997-07-02 |
1999-01-14 |
Zeneca Limited |
Triazine derivatives and their use as antibacterial agents
|
|
GB9714383D0
(en)
|
1997-07-08 |
1997-09-10 |
Pfizer Ltd |
Improved process
|
|
US6100291A
(en)
|
1998-03-16 |
2000-08-08 |
Allelix Biopharmaceuticals Inc. |
Pyrrolidine-indole compounds having 5-HT6 affinity
|
|
US6020525A
(en)
|
1998-03-19 |
2000-02-01 |
Hoffmann-La Roche Inc. |
(2S,2'R,3'R)-2-(2,3-dicarboxyl-cyclopropyl)-glycine (DCG-1/4) and 3 H-DCG-1/4 and to process for the preparation thereof
|
|
US6214879B1
(en)
|
1998-03-24 |
2001-04-10 |
Virginia Commonwealth University |
Allosteric inhibitors of pyruvate kinase
|
|
JP2002507557A
(ja)
|
1998-03-26 |
2002-03-12 |
デパートメント オブ ジ アーミー, ユー.エス. ガバメント |
抗生物質抵抗性感染の処置のための置換芳香族化合物
|
|
DE19826671A1
(de)
|
1998-06-16 |
1999-12-23 |
Hoechst Schering Agrevo Gmbh |
1,3-Oxazolin- und 1,3-Thiazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
|
|
FR2780057B1
(fr)
|
1998-06-18 |
2002-09-13 |
Sanofi Sa |
Phenoxypropanolamines, procede pour leur preparation et compositions pharmaceutiques les contenant
|
|
AUPP466598A0
(en)
|
1998-07-14 |
1998-08-06 |
University Of Newcastle Research Associates Limited, The |
Product and process
|
|
TWI250152B
(en)
|
1998-07-21 |
2006-03-01 |
Eisai Co Ltd |
N,N-substituted cyclic amine compounds used as calcium antagonizer
|
|
CO5140073A1
(es)
|
1998-10-08 |
2002-03-22 |
Smithkline Beecham Plc |
Derivados de 2,3,4,5-tetrahidro-1h-3-benzapina
|
|
WO2000053591A1
(de)
|
1999-03-08 |
2000-09-14 |
Bayer Aktiengesellschaft |
Thiazolylharnstoff-derivate und ihre verwendung als antivirale mittel
|
|
MXPA02001160A
(es)
|
1999-08-04 |
2002-07-02 |
Millennium Pharm Inc |
Compuestos que se unen a los receptores para melanocortina-4, y metodo de uso de estos.
|
|
CN1177258C
(zh)
|
1999-10-26 |
2004-11-24 |
富士胶片株式会社 |
光热敏成像材料
|
|
DE19955824A1
(de)
|
1999-11-20 |
2001-06-13 |
Schott Spezialglas Gmbh |
Verfahren und Vorrichtung zum Schneiden eines Werkstückes aus sprödbrüchigem Werkstoff
|
|
CA2389681C
(en)
|
1999-11-26 |
2010-11-02 |
Shionogi & Co., Ltd. |
Npy y5 antagonist
|
|
JP4782342B2
(ja)
|
1999-12-17 |
2011-09-28 |
サノフィ−アベンティス |
フェノキシプロパノールアミン類、それらの製造方法およびそれらを含む医薬組成物
|
|
IL150650A0
(en)
|
2000-01-20 |
2003-02-12 |
Eisai Co Ltd |
Piperidine derivatives and pharmaceutical compositions containing the same
|
|
DK1257550T3
(da)
|
2000-02-04 |
2006-03-27 |
Portola Pharm Inc |
Blodplade-ADP-receptor-inhibitor
|
|
GB0004886D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
JP2001261653A
(ja)
|
2000-03-17 |
2001-09-26 |
Sankio Chemical Co Ltd |
ピリジン誘導体の合成法
|
|
AU7866701A
(en)
|
2000-05-08 |
2001-11-20 |
Shiv Kumar Agarwal |
Antibacterial chiral 8-(substituted piperidino)-benzo (i, j) quinolizines, processes, compositions and methods of treatment
|
|
EP1578341A2
(en)
|
2000-10-11 |
2005-09-28 |
Tularik Inc. |
Modulation of ccr4 function
|
|
ES2280417T3
(es)
|
2000-10-26 |
2007-09-16 |
Smithkline Beecham Plc |
Derivados de benzoxazinona, su preparacion y uso.
|
|
JP2005519848A
(ja)
|
2000-11-02 |
2005-07-07 |
スローン−ケッタリング・インスティテュート・フォー・キャンサー・リサーチ |
Hsp90に結合するための小分子組成物
|
|
SE0100326D0
(sv)
|
2001-02-02 |
2001-02-02 |
Astrazeneca Ab |
New compounds
|
|
AUPR392301A0
(en)
|
2001-03-23 |
2001-04-26 |
University Of Newcastle Research Associates Limited, The |
Protein phosphatase inhibitors
|
|
WO2002095063A1
(en)
|
2001-05-23 |
2002-11-28 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Pyruvate-kinase as a novel target molecule
|
|
DE10139416A1
(de)
|
2001-08-17 |
2003-03-06 |
Aventis Pharma Gmbh |
Aminoalkyl substituierte aromatische Bicyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US7173032B2
(en)
|
2001-09-21 |
2007-02-06 |
Reddy Us Therapeutics, Inc. |
Methods and compositions of novel triazine compounds
|
|
US7241890B2
(en)
|
2001-10-30 |
2007-07-10 |
Conforma Therapeutics Corporation |
Purine analogs having HSP90-inhibiting activity
|
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
AU2003206787A1
(en)
|
2002-02-06 |
2003-09-02 |
Ciba Specialty Chemicals Holding Inc. |
Sulfonate derivatives and the use therof as latent acids
|
|
US6995144B2
(en)
|
2002-03-14 |
2006-02-07 |
Eisai Co., Ltd. |
Nitrogen containing heterocyclic compounds and medicines containing the same
|
|
AR040336A1
(es)
|
2002-06-26 |
2005-03-30 |
Glaxo Group Ltd |
Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
|
|
JP2005532077A
(ja)
|
2002-07-10 |
2005-10-27 |
オンコセラピー・サイエンス株式会社 |
腸型胃腫瘍の診断法
|
|
TW200403243A
(en)
|
2002-07-18 |
2004-03-01 |
Wyeth Corp |
1-Heterocyclylalkyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
|
|
CA2493625A1
(en)
|
2002-07-25 |
2004-02-19 |
Pharmacia Italia S.P.A. |
Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
|
|
JP2005537290A
(ja)
|
2002-07-25 |
2005-12-08 |
ファルマシア・イタリア・エス・ピー・エー |
キナーゼ阻害剤として活性なビシクロピラゾール類、その製造方法、およびそれを含有する薬学的組成物
|
|
ES2445208T3
(es)
|
2002-07-29 |
2014-02-28 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidindiamina para uso en métodos para tratar o prevenir enfermedades autoinmunitarias
|
|
WO2004024676A1
(de)
|
2002-09-06 |
2004-03-25 |
Schebo®Biotech Ag |
Verbindungen zur modulation des glykolyse-enzym-und/oder transaminase-komplexes
|
|
JP2004175674A
(ja)
|
2002-11-25 |
2004-06-24 |
Toyo Ink Mfg Co Ltd |
有機エレクトロルミネッセンス素子材料およびそれを使用した有機エレクトロルミネッセンス素子
|
|
EP1437145A1
(en)
|
2003-01-07 |
2004-07-14 |
Schering AG |
Enhanced scintigraphic imaging agents for imaging of infection and inflammation
|
|
WO2004072081A1
(en)
|
2003-02-10 |
2004-08-26 |
Cellular Genomics, Inc. |
Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity
|
|
MXPA05009719A
(es)
|
2003-03-11 |
2005-10-18 |
Pharmacia Italia Spa |
Derivados de biciclo-pirazol activos como inhibidores de cinasa, procedimiento para su preparacion y composiciones farmaceuticas que los comprenden.
|
|
US7449464B2
(en)
|
2003-03-12 |
2008-11-11 |
Kudos Pharmaceuticals Limited |
Phthalazinone derivatives
|
|
DE10316081A1
(de)
|
2003-04-08 |
2004-10-21 |
Morphochem AG Aktiengesellschaft für kombinatorische Chemie |
Neue Verbindungen mit antibakterieller Aktivität
|
|
ATE467616T1
(de)
|
2003-04-11 |
2010-05-15 |
High Point Pharmaceuticals Llc |
Verbindungen mit aktivität an der 11beta- hydroxasteroiddehydrogenase
|
|
WO2004104000A1
(ja)
|
2003-05-23 |
2004-12-02 |
Japan Tobacco Inc. |
トリサイクリック縮合環化合物およびその医薬用途
|
|
EP3305919A1
(en)
|
2003-06-10 |
2018-04-11 |
The Trustees of Boston University |
Detection methods for disorders of the lung
|
|
SI1643998T1
(sl)
|
2003-07-03 |
2007-12-31 |
Hoffmann La Roche |
Dvojni nk1/nk3 antagonisti za zdravljenje shizofrenije
|
|
GB0317484D0
(en)
|
2003-07-25 |
2003-08-27 |
Pfizer Ltd |
Nicotinamide derivatives useful as pde4 inhibitors
|
|
CN101712653A
(zh)
|
2003-07-30 |
2010-05-26 |
泽农医药公司 |
哒嗪衍生物和它们作为治疗剂的用途
|
|
KR20060036106A
(ko)
|
2003-07-30 |
2006-04-27 |
제논 파마슈티칼스 인크. |
피리딜 유도체 및 그의 치료제로서의 용도
|
|
GB0319150D0
(en)
|
2003-08-14 |
2003-09-17 |
Glaxo Group Ltd |
Novel compounds
|
|
US7749999B2
(en)
|
2003-09-11 |
2010-07-06 |
Itherx Pharmaceuticals, Inc. |
Alpha-ketoamides and derivatives thereof
|
|
KR20060070572A
(ko)
|
2003-09-18 |
2006-06-23 |
콘포마 세러퓨틱스 코포레이션 |
Hsp90-저해제로서의 신규 헤테로시클릭 화합물
|
|
DE10353910A1
(de)
|
2003-11-18 |
2005-06-09 |
Studiengesellschaft Kohle Mbh |
Verfahren zur Synthese optisch aktiver Piperidine
|
|
AR046959A1
(es)
|
2003-12-18 |
2006-01-04 |
Tibotec Pharm Ltd |
Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
|
|
DE602004021135D1
(de)
|
2003-12-18 |
2009-06-25 |
Tibotec Pharm Ltd |
Aminobenzimidazolderivate als inhibitoren der replikation des respiratory syncytial virus
|
|
RU2369606C2
(ru)
|
2003-12-18 |
2009-10-10 |
Тиботек Фармасьютикалз Лтд. |
Производные 5- или 6-замещенных бензимидазолов в качестве ингибиторов репликации респираторного синцитиального вируса
|
|
EP1697343B1
(en)
|
2003-12-18 |
2009-07-01 |
Tibotec Pharmaceuticals Ltd. |
Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication
|
|
ATE501135T1
(de)
|
2003-12-18 |
2011-03-15 |
Tibotec Pharm Ltd |
Piperidinamino-benzimidazol-derivate al respiratorisches syncytialvirus replikation inhibitoren
|
|
US7422837B2
(en)
|
2004-02-16 |
2008-09-09 |
Fujifilm Corporation |
Photosensitive composition
|
|
US7435830B2
(en)
|
2004-03-03 |
2008-10-14 |
Chemocentryx, Inc. |
Bicyclic and bridged nitrogen heterocycles
|
|
US7435831B2
(en)
|
2004-03-03 |
2008-10-14 |
Chemocentryx, Inc. |
Bicyclic and bridged nitrogen heterocycles
|
|
EP1725238A4
(en)
|
2004-03-17 |
2009-04-01 |
Glaxo Group Ltd |
M 3 MUSCARINACETYLCHOLINE RECEPTOR ANTAGONISTS
|
|
US20070185090A1
(en)
|
2004-03-17 |
2007-08-09 |
Jakob Busch-Petersen |
Muscarinic acetylchoine receptor antagonists
|
|
US7335770B2
(en)
|
2004-03-24 |
2008-02-26 |
Reddy U5 Therapeutics, Inc. |
Triazine compounds and their analogs, compositions, and methods
|
|
TWI391387B
(zh)
|
2004-05-12 |
2013-04-01 |
Eisai R&D Man Co Ltd |
具有哌啶環之吲哚衍生物
|
|
AU2005265148B2
(en)
|
2004-06-21 |
2011-01-20 |
Merck Sharp & Dohme Corp. |
Aminocyclohexanes as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
EP1792181B1
(en)
|
2004-06-21 |
2010-11-17 |
Progenra Inc. |
Diagnostic and screening methods and kits associated with proteolytic activity
|
|
DE102004039789A1
(de)
|
2004-08-16 |
2006-03-02 |
Sanofi-Aventis Deutschland Gmbh |
Arylsubstituierte polycyclische Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2006023608A2
(en)
|
2004-08-18 |
2006-03-02 |
Elixir Pharmaceuticals, Inc. |
Growth-hormone secretagogues
|
|
DE102004041163A1
(de)
|
2004-08-25 |
2006-03-02 |
Morphochem Aktiengesellschaft für kombinatorische Chemie |
Neue Verbindungen mit antibakterieller Aktivität
|
|
CA2580857A1
(en)
|
2004-09-20 |
2006-09-28 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
|
|
EP2289510A1
(en)
|
2004-09-20 |
2011-03-02 |
Xenon Pharmaceuticals Inc. |
Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
|
|
WO2006038172A1
(en)
|
2004-10-05 |
2006-04-13 |
Actelion Pharmaceuticals Ltd |
New piperidine antibiotics
|
|
US20080255134A1
(en)
|
2004-11-30 |
2008-10-16 |
Artesian Therapeutics, Inc. |
Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase
|
|
US7968574B2
(en)
|
2004-12-28 |
2011-06-28 |
Kinex Pharmaceuticals, Llc |
Biaryl compositions and methods for modulating a kinase cascade
|
|
US7834181B2
(en)
|
2005-02-01 |
2010-11-16 |
Slaon-Kettering Institute For Cancer Research |
Small-molecule Hsp90 inhibitors
|
|
GT200600046A
(es)
|
2005-02-09 |
2006-09-25 |
|
Terapia de combinacion
|
|
MX2007010227A
(es)
|
2005-02-25 |
2007-11-07 |
Serenex Inc |
Derivados de tetrahidroindolona y tetrahidroindazolona.
|
|
WO2006099884A1
(en)
|
2005-03-24 |
2006-09-28 |
Actelion Percurex Ag |
Beta-aminoalcohol antibiotics
|
|
EP1868601A4
(en)
|
2005-04-07 |
2008-12-10 |
Merck & Co Inc |
MITOTIC KINESINE HEMMER
|
|
GB0510204D0
(en)
|
2005-05-19 |
2005-06-22 |
Chroma Therapeutics Ltd |
Enzyme inhibitors
|
|
WO2006130469A1
(en)
|
2005-05-27 |
2006-12-07 |
Oregon Health & Science University |
Stimulation of neurite outgrowth by small molecules
|
|
WO2006137485A1
(ja)
|
2005-06-24 |
2006-12-28 |
Toyama Chemical Co., Ltd. |
新規な含窒素複素環化合物およびその塩
|
|
GB0514018D0
(en)
|
2005-07-07 |
2005-08-17 |
Ionix Pharmaceuticals Ltd |
Chemical compounds
|
|
MX2008000574A
(es)
|
2005-07-11 |
2008-03-14 |
Sanofi Aventis |
Nuevos derivados de 2,4-dianilinopirimidinas, la preparacion de los mismos, su uso como medicamentos, composiciones farmaceuticas y, en particular, como inhibidores ikk.
|
|
EP1910385B1
(en)
|
2005-08-04 |
2013-07-24 |
Sirtris Pharmaceuticals, Inc. |
Benzothiazoles and thiazolopyridines as sirtuin modulators
|
|
JP2009511530A
(ja)
|
2005-10-13 |
2009-03-19 |
モルフォケム アクチェンゲゼルシャフト フュア コンビナトリシェ ヘミー |
抗菌活性を有する5−キノリン誘導体
|
|
GB0600967D0
(en)
|
2006-01-18 |
2006-03-01 |
Imp Innovations Ltd |
Methods
|
|
CA2636757A1
(en)
|
2006-01-25 |
2007-08-02 |
Tesfaye Biftu |
Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
EP2786749A1
(en)
|
2006-02-03 |
2014-10-08 |
Nicox S.A. |
Use of nitrooxyderivative of drug for the treatment of muscular dystrophies
|
|
WO2007097931A2
(en)
|
2006-02-15 |
2007-08-30 |
Merck & Co., Inc. |
Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
CA2637531A1
(en)
|
2006-02-17 |
2007-08-30 |
Memory Pharmaceuticals Corporation |
Compounds having 5-ht6 receptor affinity
|
|
JP2007246885A
(ja)
|
2006-02-20 |
2007-09-27 |
Toyo Ink Mfg Co Ltd |
光機能材料
|
|
TW200806669A
(en)
|
2006-03-28 |
2008-02-01 |
Merck & Co Inc |
Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
NZ572367A
(en)
|
2006-05-16 |
2011-09-30 |
Gilead Sciences Inc |
Fused cyclic compounds as integrase inhibitors
|
|
AU2007254357B2
(en)
|
2006-05-16 |
2011-07-21 |
Merck Sharp & Dohme Corp. |
Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
|
JP5026511B2
(ja)
|
2006-05-18 |
2012-09-12 |
エフ.ホフマン−ラ ロシュ アーゲー |
アデノシンa2bレセプターアンタゴニストとしてのチアゾロ−ピラミジン/ピリジン尿素誘導体
|
|
CN101454338A
(zh)
|
2006-05-26 |
2009-06-10 |
卡拉治疗学股份有限公司 |
κ阿片样受体肽的N-氧化物
|
|
GB0610680D0
(en)
|
2006-05-31 |
2006-07-12 |
Istituto Di Ricerche D Biolog |
Therapeutic compounds
|
|
JP2007328090A
(ja)
|
2006-06-07 |
2007-12-20 |
Fujifilm Corp |
感光性組成物、感光性フィルム、パターン形成方法、及びプリント基板
|
|
US10336757B2
(en)
|
2006-06-30 |
2019-07-02 |
Sloan-Kettering Institute For Cancer Research |
Treatment of neurodegenerative diseases through inhibition of HSP90
|
|
JP2008031064A
(ja)
|
2006-07-27 |
2008-02-14 |
Astellas Pharma Inc |
ジアシルピペラジン誘導体
|
|
WO2008094203A2
(en)
|
2006-08-03 |
2008-08-07 |
Microbiotix, Inc. |
Polar ester prodrugs of heterocyclic hybrid antibacterial compounds and salts thereof
|
|
ES2614931T3
(es)
|
2006-08-04 |
2017-06-02 |
Beth Israel Deaconess Medical Center |
Inhibidores de la piruvato cinasa y métodos de tratamiento de enfermedad
|
|
JP2008063256A
(ja)
|
2006-09-06 |
2008-03-21 |
Astellas Pharma Inc |
β‐アミノ酸誘導体
|
|
WO2008032905A1
(en)
|
2006-09-13 |
2008-03-20 |
Hurim Biocell Co., Ltd. |
Genes involved in differentiation of human stem cell lines and the microarray kit containing these genes
|
|
US7875603B2
(en)
|
2006-09-21 |
2011-01-25 |
Nova Southeastern University |
Specific inhibitors for vascular endothelial growth factor receptors
|
|
TWI405763B
(zh)
|
2006-11-02 |
2013-08-21 |
Targacept Inc |
菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
|
|
MX2009005000A
(es)
|
2006-11-10 |
2009-10-12 |
Cara Therapeutics Inc |
Amidas de peptidos sinteticos.
|
|
FR2910298A1
(fr)
|
2006-12-20 |
2008-06-27 |
Oreal |
Composition tinctoriale contenant une silicone reactive, un colorant fluorescent ou azurant optique, procede de coloration utilisant la composition
|
|
US8466150B2
(en)
|
2006-12-28 |
2013-06-18 |
Abbott Laboratories |
Inhibitors of poly(ADP-ribose)polymerase
|
|
DK2120579T3
(da)
|
2006-12-28 |
2014-02-03 |
Abbvie Inc |
Inhibitorer af poly(ADP-ripose)polymerase
|
|
JP5401329B2
(ja)
|
2007-03-20 |
2014-01-29 |
キュリス,インコーポレイテッド |
Hsp90インヒビターとしての縮合アミノピリジン
|
|
WO2008120003A1
(en)
|
2007-04-03 |
2008-10-09 |
Astrazeneca Ab |
Substituted piperidines for use in the treatment of bacterial infections
|
|
AU2008248996A1
(en)
|
2007-04-27 |
2008-11-13 |
Sanofi-Aventis |
2 -heteroaryl- pyrrolo [3, 4-C] pyrrole derivatives and their use as SCD inhibitors
|
|
WO2008139585A1
(ja)
|
2007-05-10 |
2008-11-20 |
Toray Engineering Co., Ltd. |
初期亀裂形成機構
|
|
WO2009001126A1
(en)
|
2007-06-27 |
2008-12-31 |
Astrazeneca Ab |
Substituted piperidine derivatives and their use as antibaterial agents
|
|
FR2918061B1
(fr)
|
2007-06-28 |
2010-10-22 |
Sanofi Aventis |
Derives de 6-cycloamino-3-(pyridin-4-yl)imidazo°1,2-b!- pyridazine,leur preparation et leur application en therapeutique.
|
|
US20090023727A1
(en)
|
2007-07-05 |
2009-01-22 |
Muhammad Hashim Javaid |
Phthalazinone derivatives
|
|
FR2918986B1
(fr)
|
2007-07-19 |
2009-09-04 |
Sanofi Aventis Sa |
Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique
|
|
EP2019318A1
(en)
|
2007-07-27 |
2009-01-28 |
Erasmus University Medical Center Rotterdam |
Protein markers for cardiovascular events
|
|
WO2009025781A1
(en)
|
2007-08-16 |
2009-02-26 |
Beth Israel Deaconess Medical Center |
Activators of pyruvate kinase m2 and methods of treating disease
|
|
CA2696211C
(en)
|
2007-08-21 |
2015-05-26 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
ES2524787T3
(es)
|
2007-11-15 |
2014-12-12 |
Msd Italia S.R.L. |
Derivados de piridazinona como inhibidores de PARP
|
|
US20090291921A1
(en)
|
2007-11-20 |
2009-11-26 |
Gilead Sciences, Inc. |
Integrase inhibitors
|
|
TW200938203A
(en)
|
2007-12-17 |
2009-09-16 |
Intervet Int Bv |
Anthelmintic agents and their use
|
|
JP5258280B2
(ja)
|
2007-12-18 |
2013-08-07 |
富士フイルム株式会社 |
顔料分散組成物、感光性樹脂組成物、カラーフィルタおよびその製造方法
|
|
CA2709784A1
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
FR2926555B1
(fr)
|
2008-01-22 |
2010-02-19 |
Sanofi Aventis |
Derives bicycliques de carboxamides azabicycliques, leur preparation et leur application en therapeutique
|
|
AR070221A1
(es)
|
2008-01-23 |
2010-03-25 |
Astrazeneca Ab |
Derivados de ftalazinona inhibidores de polimerasas, composiciones farmaceuticas que los contienen y usos de los mismos para prevenir y/o tratar tumores cancerigenos,lesiones isquemicas y otras enfermedades asociadas.
|
|
DE102008010661A1
(de)
|
2008-02-22 |
2009-09-03 |
Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG |
Verfahren zur Herstellung von Pyridin-2-Boronsäure und Derivaten davon
|
|
JP2009212473A
(ja)
|
2008-03-06 |
2009-09-17 |
Fujifilm Corp |
金属用研磨液、及び化学的機械的研磨方法
|
|
EP2257340A2
(en)
|
2008-04-04 |
2010-12-08 |
BioMarin IGA Limited |
Compounds for treating muscular dystrophy
|
|
WO2009136889A1
(en)
|
2008-05-08 |
2009-11-12 |
Nova Southeastern University |
Specific inhibitors for vascular endothelial growth factor receptors
|
|
GB0811304D0
(en)
|
2008-06-19 |
2008-07-30 |
Ucb Pharma Sa |
Therapeutic agents
|
|
US20100022581A1
(en)
|
2008-07-02 |
2010-01-28 |
Memory Pharmaceuticals Corporation |
Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity
|
|
CA2734744A1
(en)
|
2008-08-20 |
2010-02-25 |
Michael Eissenstat |
Hcv protease inhibitors
|
|
WO2010028179A1
(en)
|
2008-09-03 |
2010-03-11 |
Dr. Reddy's Laboratories Ltd. |
Heterocyclic compounds as gata modulators
|
|
WO2010028761A1
(de)
|
2008-09-09 |
2010-03-18 |
Sanofi-Aventis |
2-heteroaryl-pyrrolo[3, 4-c]pyrrol-derivate und ihre verwendung als scd inhibitoren
|
|
AU2009303335B2
(en)
|
2008-10-09 |
2016-05-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Activators of human pyruvate kinase
|
|
JO2870B1
(en)
|
2008-11-13 |
2015-03-15 |
ميرك شارب اند دوهم كورب |
Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes
|
|
US20110230493A1
(en)
|
2008-11-21 |
2011-09-22 |
Pfizer Inc. |
1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors
|
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
|
JP2010192782A
(ja)
|
2009-02-20 |
2010-09-02 |
Toyo Ink Mfg Co Ltd |
光電変換素子用材料及び光電変換素子
|
|
US8143244B2
(en)
|
2009-02-26 |
2012-03-27 |
Bristol-Myers Squibb Company |
Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
|
|
AU2010223919B2
(en)
|
2009-03-13 |
2016-03-31 |
Les Laboratoires Servier |
Methods and compositions for cell-proliferation-related disorders
|
|
TW201041868A
(en)
|
2009-03-20 |
2010-12-01 |
Intervet Int Bv |
Anthelmintic agents and their use
|
|
WO2010108268A1
(en)
|
2009-03-23 |
2010-09-30 |
Merck Frosst Canada Ltd. |
Heterocyclic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
|
WO2010118063A2
(en)
|
2009-04-06 |
2010-10-14 |
Agios Pharmaceuticals, Inc. |
Therapeutic compositions and related methods of use
|
|
WO2010129596A1
(en)
|
2009-05-04 |
2010-11-11 |
Agios Pharmaceuticals, Inc. |
Pmk2 modulators for use in the treatment of cancer
|
|
CN102459251B
(zh)
|
2009-05-14 |
2015-05-20 |
詹森药业有限公司 |
作为白三烯a4水解酶的调节剂的具有两个稠合双环杂芳基部分的化合物
|
|
BRPI1010974A2
(pt)
|
2009-05-22 |
2019-09-24 |
Exelixis Inc |
benzoxazepinas baseada em inibidores p13k/ m tor contra doenças proliferativas
|
|
US8377639B2
(en)
|
2009-06-26 |
2013-02-19 |
University Of Massachusetts |
Compounds for modulating RNA binding proteins and uses therefor
|
|
ES2618630T3
(es)
|
2009-06-29 |
2017-06-21 |
Agios Pharmaceuticals, Inc. |
Composiciones terapéuticas y métodos de uso relacionados
|
|
RU2561132C2
(ru)
|
2009-06-29 |
2015-08-20 |
Аджиос Фармасьютикалз, Инк. |
Производные хинолинсульфонамидов и их применение для модулирования пкм2 активности
|
|
WO2012174126A1
(en)
|
2011-06-13 |
2012-12-20 |
Universyty Of Medicine And Dentistry Of New Jesey |
METHOD OF INHIBITING NONSENSE-MEDIATED mRNA DECAY
|
|
KR101906146B1
(ko)
|
2009-08-17 |
2018-10-10 |
메모리얼 슬로안-케터링 캔서 센터 |
열 충격 단백질 결합 화합물, 조성물, 및 이의 제조 방법 및 사용 방법
|
|
US8354403B2
(en)
|
2009-08-27 |
2013-01-15 |
Merck Sharp & Dohme Corp. |
Pyrrolidine derived beta 3 adrenergic receptor agonists
|
|
WO2011037793A1
(en)
|
2009-09-25 |
2011-03-31 |
Merck Sharp & Dohme Corp. |
Substituted aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
|
WO2011044377A2
(en)
|
2009-10-09 |
2011-04-14 |
Cell Point, Llc |
Chelator-targeting ligand conjugates for cardiovascular imaging
|
|
EP3561077B1
(en)
|
2009-10-21 |
2022-12-21 |
Les Laboratoires Servier |
Methods for cell-proliferation-related disorders
|
|
WO2011050211A2
(en)
|
2009-10-21 |
2011-04-28 |
Agios Pharmaceuticals, Inc. |
Methods and compositions for cell-proliferation-related disorders
|
|
WO2011060321A1
(en)
|
2009-11-16 |
2011-05-19 |
Chdi, Inc. |
Transglutaminase tg2 inhibitors, pharmaceutical compositions, and methods of use thereof
|
|
EP2501797A4
(en)
|
2009-11-18 |
2013-04-17 |
Myriant Corp |
TECHNIQUES OF MICROBES FOR THE EFFECTIVE MANUFACTURE OF CHEMICALS
|
|
KR20110096442A
(ko)
|
2010-02-22 |
2011-08-30 |
주식회사 이엔에프테크놀로지 |
칼라필터용 착색 감광성 수지 조성물
|
|
US8853212B2
(en)
|
2010-02-22 |
2014-10-07 |
Merck Sharp & Dohme Corp |
Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes
|
|
CN101812063B
(zh)
|
2010-03-18 |
2012-04-25 |
中国医学科学院医药生物技术研究所 |
α-萘磺酰胺基五元杂环类化合物及其抑瘤活性
|
|
US9018227B2
(en)
|
2010-03-19 |
2015-04-28 |
Indiana State University |
Nicotinic acetylcholine receptor agonists
|
|
US20130109672A1
(en)
|
2010-04-29 |
2013-05-02 |
The United States Of America,As Represented By The Secretary, Department Of Health And Human Service |
Activators of human pyruvate kinase
|
|
WO2011146358A1
(en)
|
2010-05-21 |
2011-11-24 |
Merck Sharp & Dohme Corp. |
Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
|
JP2011246649A
(ja)
|
2010-05-28 |
2011-12-08 |
Mitsubishi Chemicals Corp |
顔料分散液、着色樹脂組成物、カラーフィルタ、並びに液晶表示装置及び有機elディスプレイ
|
|
WO2012002577A1
(ja)
|
2010-06-30 |
2012-01-05 |
富士フイルム株式会社 |
新規なニコチンアミド誘導体またはその塩
|
|
JP2013532184A
(ja)
|
2010-07-12 |
2013-08-15 |
ファイザー・リミテッド |
電位開口型ナトリウムチャネル阻害剤として有用なn−スルホニルベンズアミド誘導体
|
|
JP2013532185A
(ja)
|
2010-07-12 |
2013-08-15 |
ファイザー・リミテッド |
化合物
|
|
EP2593433B1
(en)
|
2010-07-12 |
2014-11-26 |
Pfizer Limited |
N-sulfonylbenzamides as inhibitors of voltage-gated sodium channels
|
|
CN102372716A
(zh)
|
2010-08-09 |
2012-03-14 |
江苏恒瑞医药股份有限公司 |
酞嗪酮类衍生物、其制备方法及其在医药上的应用
|
|
CN102372706A
(zh)
|
2010-08-09 |
2012-03-14 |
江苏恒瑞医药股份有限公司 |
酞嗪酮类衍生物、其制备方法及其在医药上的应用
|
|
EP2632920A1
(en)
|
2010-10-27 |
2013-09-04 |
Dynamix Pharmaceuticals Ltd. |
Sulfonamides for the modulation of pkm2
|
|
US20140080810A1
(en)
|
2010-11-15 |
2014-03-20 |
Exelixis, Inc. |
Benzoxazepines as Inhibitors of PI3K/mTOR and Methods of Their Use and Manufacture
|
|
US20140107100A1
(en)
|
2010-11-24 |
2014-04-17 |
Exelixis, Inc. |
Benzoxazepines as Inhibitors of PI3K/mTOR and Methods of Their Use and Manufacture
|
|
KR101528688B1
(ko)
|
2010-12-02 |
2015-06-12 |
상하이 드 노보 파마테크 컴퍼니 리미티드 |
헤테로사이클릭 유도체, 이의 제조 방법 및 이의 의학적 용도
|
|
EP2651405A2
(en)
|
2010-12-14 |
2013-10-23 |
Electrophoretics Limited |
Casein kinase 1 (ck1 ) inhibitors
|
|
CA2821975A1
(en)
|
2010-12-17 |
2012-06-21 |
Shunqi Yan |
N-(4-(azetidine-1-carbonyl)phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase m2 pkm2 modulators
|
|
WO2012088314A1
(en)
|
2010-12-21 |
2012-06-28 |
Agios Pharmaceuticals, Inc. |
Bicyclic pkm2 activators
|
|
TWI549947B
(zh)
|
2010-12-29 |
2016-09-21 |
阿吉歐斯製藥公司 |
治療化合物及組成物
|
|
KR20190002733A
(ko)
|
2010-12-30 |
2019-01-08 |
파운데이션 메디신 인코포레이티드 |
종양 샘플의 다유전자 분석의 최적화
|
|
WO2012092485A1
(en)
|
2010-12-31 |
2012-07-05 |
Anthrogenesis Corporation |
Enhancement of placental stem cell potency using modulatory rna molecules
|
|
JP2012188475A
(ja)
|
2011-03-09 |
2012-10-04 |
Toyo Ink Sc Holdings Co Ltd |
顔料分散剤、それを用いた顔料組成物、着色組成物およびカラーフィルタ
|
|
JP2012188474A
(ja)
|
2011-03-09 |
2012-10-04 |
Toyo Ink Sc Holdings Co Ltd |
顔料分散剤、それを用いた顔料組成物、着色組成物およびカラーフィルタ
|
|
CN102206217A
(zh)
|
2011-03-17 |
2011-10-05 |
盛世泰科生物医药技术(苏州)有限公司 |
杂环化合物作为二肽基肽酶抑制剂用于治疗或预防糖尿病
|
|
WO2012139010A1
(en)
|
2011-04-08 |
2012-10-11 |
University Of Kansas |
Grp94 inhibitors
|
|
ES2746558T3
(es)
|
2011-05-03 |
2020-03-06 |
Agios Pharmaceuticals Inc |
Activadores de piruvato cinasa R para uso en terapia
|
|
EP3372230B1
(en)
*
|
2011-05-03 |
2020-08-12 |
Agios Pharmaceuticals, Inc. |
Pyruvate kinase activators for use for increasing lifetime of the red blood cells and treating anemia
|
|
WO2012151440A1
(en)
|
2011-05-03 |
2012-11-08 |
Agios Pharmaceuticals, Inc. |
Pyruvate kinase activators for use for increasing lifetime of the red blood cells and treating anemia
|
|
WO2012151448A1
(en)
|
2011-05-03 |
2012-11-08 |
Agios Pharmaceuticals, Inc. |
Pyruvate kinase activators for use in therapy
|
|
SG194697A1
(en)
|
2011-05-03 |
2013-12-30 |
Agios Pharmaceuticals Inc |
Pyruvate kinase activators for use in therapy
|
|
WO2012160447A1
(en)
|
2011-05-25 |
2012-11-29 |
Dynamix Pharmaceuticals Ltd. |
3, 5 -diphenyl- substituted pyrazolines for the treatment of cancer, proliferative, inflammatory or autoimmune diseases
|
|
GB201108825D0
(en)
|
2011-05-25 |
2011-07-06 |
Univ Dundee |
Morpholino compounds, uses and methods
|
|
RU2472794C1
(ru)
|
2011-05-25 |
2013-01-20 |
Федеральное государственное образовательное учреждение высшего профессионального образования Астраханский государственный технический университет (ФГОУ ВПО АГТУ) |
Новые бициклические производные пирролидинов, обладающие антиоксидантной активностью, и способ их получения
|
|
CA2838738A1
(en)
|
2011-06-29 |
2013-01-03 |
Merck Sharp & Dohme Corp. |
Novel crystalline forms of a dipeptidyl peptidase-iv inhibitor
|
|
DK2729806T3
(en)
|
2011-07-08 |
2017-05-15 |
Sloan-Kettering Inst For Cancer Res |
APPLICATIONS OF MARKED HSP90 INHIBITORS
|
|
JO3611B1
(ar)
|
2011-08-10 |
2020-08-27 |
Janssen Sciences Ireland Uc |
سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم
|
|
CN102952139B
(zh)
|
2011-08-30 |
2016-08-10 |
上海药明康德新药开发有限公司 |
反式-3a-氟吡咯烷[3,4-C]并环化合物及其制备方法
|
|
US9056867B2
(en)
|
2011-09-16 |
2015-06-16 |
Novartis Ag |
N-substituted heterocyclyl carboxamides
|
|
WO2013056153A1
(en)
|
2011-10-13 |
2013-04-18 |
Kung Charles |
Activators of pyruvate kinase m2 and methods of treating disease
|
|
JP5468056B2
(ja)
|
2011-12-15 |
2014-04-09 |
富士フイルム株式会社 |
電気泳動組成物、マイクロカプセル、及び、電気泳動表示素子
|
|
ES2643403T3
(es)
|
2011-12-28 |
2017-11-22 |
Global Blood Therapeutics, Inc. |
Compuestos de benzaldehído sustituidos y métodos para su uso en el aumento de la oxigenación tisular
|
|
HK1203412A1
(en)
|
2011-12-28 |
2015-10-30 |
Global Blood Therapeutics, Inc. |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
|
|
US20150291514A1
(en)
|
2012-01-04 |
2015-10-15 |
Pfizer Limted |
N-Aminosulfonyl Benzamides
|
|
JP2015083542A
(ja)
|
2012-02-08 |
2015-04-30 |
大日本住友製薬株式会社 |
3位置換プロリン誘導体
|
|
JP5895583B2
(ja)
|
2012-02-21 |
2016-03-30 |
コニカミノルタ株式会社 |
有機エレクトロルミネッセンス素子、照明装置および表示装置ならびに有機エレクトロルミネッセンス素子の製造方法
|
|
US9493481B2
(en)
|
2012-02-23 |
2016-11-15 |
Vanderbilt University |
Substituted 5-aminothieno[2,3—C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
|
|
WO2013127266A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Amido-benzyl sulfone and sulfoxide derivatives
|
|
EP2836482B1
(en)
|
2012-04-10 |
2019-12-25 |
The Regents of The University of California |
Compositions and methods for treating cancer
|
|
CN104718188B
(zh)
|
2012-05-22 |
2018-08-21 |
基因泰克公司 |
N-取代的苯甲酰胺类及其在治疗疼痛中的用途
|
|
US20150150935A1
(en)
|
2012-06-05 |
2015-06-04 |
Cara Therapeutics, Inc. |
Peripheral kappa receptor agonists for reducing pain and inflammation
|
|
KR101663436B1
(ko)
|
2012-07-06 |
2016-10-06 |
제넨테크, 인크. |
N-치환된 벤즈아미드 및 이의 사용 방법
|
|
CN103570722A
(zh)
|
2012-07-19 |
2014-02-12 |
中国科学院上海药物研究所 |
稠环哒嗪酮类化合物及其制备方法和用途
|
|
US9758480B2
(en)
|
2012-07-19 |
2017-09-12 |
Sumitomo Dainippon Pharma Co., Ltd. |
1-(cycloalkyl-carbonyl)proline derivative
|
|
US9156848B2
(en)
|
2012-07-23 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
Treating diabetes with dipeptidyl peptidase-IV inhibitors
|
|
CN104981466B
(zh)
|
2012-08-10 |
2019-06-14 |
爱尔兰詹森科学公司 |
抗细菌化合物
|
|
AR092211A1
(es)
|
2012-09-24 |
2015-04-08 |
Merck Patent Ges Mit Beschränkter Haftung |
Derivados de hidropirrolopirrol
|
|
KR102179599B1
(ko)
|
2012-09-25 |
2020-11-19 |
에프. 호프만-라 로슈 아게 |
이환형 유도체
|
|
DK2909181T3
(da)
|
2012-10-16 |
2017-11-20 |
Tolero Pharmaceuticals Inc |
PKM2-modulatorer og fremgangsmåder til anvendelse deraf
|
|
TWI500613B
(zh)
*
|
2012-10-17 |
2015-09-21 |
Cadila Healthcare Ltd |
新穎之雜環化合物
|
|
KR20150080619A
(ko)
|
2012-11-08 |
2015-07-09 |
아지오스 파마슈티컬스 아이엔씨. |
치료적 화합물 및 조성물
|
|
CA2894157A1
(en)
|
2012-12-21 |
2014-06-26 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
PL2938598T3
(pl)
|
2012-12-31 |
2017-05-31 |
Cadila Healthcare Limited |
Podstawione pochodne ftalazyn-1 (2H)-onu jako selektywne inhibitory polimerazy-1 poli(ADP-rybozy)
|
|
WO2014118634A1
(en)
|
2013-01-31 |
2014-08-07 |
Eustache Paramithiotis |
Type 2 diabetes biomarkers and uses thereof
|
|
CN105339507A
(zh)
|
2013-02-21 |
2016-02-17 |
托马生物科学公司 |
用于核酸分析的方法、组合物和试剂盒
|
|
AR095079A1
(es)
|
2013-03-12 |
2015-09-16 |
Hoffmann La Roche |
Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo
|
|
US9422279B2
(en)
|
2013-03-15 |
2016-08-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US10201623B2
(en)
|
2013-03-15 |
2019-02-12 |
Memorial Sloan Kettering Cancer Center |
HSP90-targeted cardiac imaging and therapy
|
|
US20140274961A1
(en)
|
2013-03-15 |
2014-09-18 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US9458139B2
(en)
|
2013-03-15 |
2016-10-04 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US9604999B2
(en)
|
2013-03-15 |
2017-03-28 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US10100043B2
(en)
|
2013-03-15 |
2018-10-16 |
Global Blood Therapeutics, Inc. |
Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
|
|
MX379235B
(es)
|
2013-03-15 |
2025-03-11 |
Global Blood Therapeutics Inc |
Compuestos y sus usos para modular la hemoglobina.
|
|
US8952171B2
(en)
|
2013-03-15 |
2015-02-10 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
US10266551B2
(en)
|
2013-03-15 |
2019-04-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
|
JP6473133B2
(ja)
|
2013-03-15 |
2019-02-20 |
アラクセス ファーマ エルエルシー |
Krasg12cの共有結合性阻害剤
|
|
WO2014139144A1
(en)
|
2013-03-15 |
2014-09-18 |
Agios Pharmaceuticals, Inc. |
Therapeutic compounds and compositions
|
|
US9802900B2
(en)
|
2013-03-15 |
2017-10-31 |
Global Blood Therapeutics, Inc. |
Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
|
|
WO2014172638A2
(en)
|
2013-04-18 |
2014-10-23 |
Brandeis University |
Inhibitors of deubiquitinating proteases
|
|
CN107417616A
(zh)
|
2013-05-01 |
2017-12-01 |
中央研究院 |
治疗β‑地中海贫血和镰状细胞病的方法和组合物
|
|
KR102084185B1
(ko)
|
2013-08-29 |
2020-03-04 |
주식회사 대웅제약 |
테트라히드로사이클로펜타피롤 유도체 및 이의 제조방법
|
|
JP6576929B2
(ja)
|
2013-09-11 |
2019-09-18 |
メルク パテント ゲーエムベーハー |
ヘテロ環化合物
|
|
CN105745206B
(zh)
|
2013-09-20 |
2019-08-13 |
生物马林药物股份有限公司 |
用于治疗疾病的葡萄糖神经酰胺合成酶抑制剂
|
|
CA2924393A1
(en)
|
2013-09-25 |
2015-04-02 |
Institute For Systems Biology |
Markers for amyotrophic lateral sclerosis (als) and presymptomatic alzheimer's desease (psad)
|
|
US9920073B2
(en)
|
2013-10-04 |
2018-03-20 |
Drexel University |
Compositions useful for inhibiting HIV-1 infection and methods using same
|
|
US9868736B2
(en)
|
2013-10-10 |
2018-01-16 |
The Regents Of The University Of Michigan |
Deubiquitinase inhibitors and methods for use of the same
|
|
EA201992707A1
(ru)
|
2013-11-18 |
2020-06-30 |
Глобал Блад Терапьютикс, Инк. |
Соединения и их применения для модуляции гемоглобина
|
|
WO2015078374A1
(en)
|
2013-11-27 |
2015-06-04 |
Genentech, Inc. |
Substituted benzamides and methods of use thereof
|
|
US20160319367A1
(en)
|
2013-12-17 |
2016-11-03 |
Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis |
Means and methods for typing a breast cancer patient and assigning therapy based on the typing
|
|
WO2015116061A1
(en)
|
2014-01-29 |
2015-08-06 |
Global Blood Therapeutics, Inc. |
1:1 adducts of sickle hemoglobin
|
|
US9248199B2
(en)
|
2014-01-29 |
2016-02-02 |
Global Blood Therapeutics, Inc. |
1:1 adducts of sickle hemoglobin
|
|
JP6366728B2
(ja)
|
2014-02-28 |
2018-08-01 |
コーニング インコーポレイテッド |
ジケトピロロピロール半導体材料、その調製方法およびその使用
|
|
CN106103446B
(zh)
|
2014-03-26 |
2019-07-30 |
豪夫迈·罗氏有限公司 |
作为自分泌运动因子(atx)和溶血磷脂酸(lpa)生产抑制剂的二环化合物
|
|
CN105037367A
(zh)
|
2014-04-18 |
2015-11-11 |
四川海思科制药有限公司 |
氨基六元环类衍生物及其在医药上的应用
|
|
CN105085528A
(zh)
|
2014-05-15 |
2015-11-25 |
成都贝斯凯瑞生物科技有限公司 |
作为二肽基肽酶-iv抑制剂的氨基四氢吡喃衍生物
|
|
US10665323B2
(en)
|
2014-05-28 |
2020-05-26 |
Roland Grafstrom |
In vitro toxicogenomics for toxicity prediction using probabilistic component modeling and a compound-induced transcriptional response pattern
|
|
MY181641A
(en)
|
2014-06-17 |
2020-12-30 |
Sichuan Haisco Pharmaceutical Co Ltd |
Amino pyran ring derivative and composition and use thereof
|
|
CN105294694B
(zh)
|
2014-06-18 |
2019-01-04 |
四川海思科制药有限公司 |
氨基六元环类衍生物及其在医药上的应用
|
|
BR112017000398A2
(pt)
|
2014-07-11 |
2018-01-23 |
Intervet Int Bv |
composto ou sal do mesmo, método de tratamento de uma infecção causada por dirofilaria immitis, e, kit.
|
|
EP3166605A1
(en)
|
2014-07-11 |
2017-05-17 |
Intervet International B.V. |
Use of anthelmintic agents against dirofilaria immitis
|
|
WO2016014522A1
(en)
|
2014-07-21 |
2016-01-28 |
Brandeis University |
Inhibitors of deubiquitinating proteases
|
|
US9862725B2
(en)
|
2014-07-21 |
2018-01-09 |
Merck Sharp & Dohme Corp. |
Process for preparing chiral dipeptidyl peptidase-IV inhibitors
|
|
WO2016022656A1
(en)
|
2014-08-05 |
2016-02-11 |
Wayne State University |
Compositions and methods for treatment of sickle cell disease
|
|
KR101837565B1
(ko)
|
2014-08-06 |
2018-03-12 |
삼성에스디아이 주식회사 |
유기 화합물, 유기 광전자 소자 및 표시 장치
|
|
CN113521314A
(zh)
|
2014-09-17 |
2021-10-22 |
纪念斯隆-凯特琳癌症中心 |
Hsp90-靶向炎症和感染成像及治疗
|
|
WO2016044650A1
(en)
|
2014-09-17 |
2016-03-24 |
Epizyme, Inc. |
Carm1 inhibitors and uses thereof
|
|
WO2016044604A1
(en)
|
2014-09-17 |
2016-03-24 |
Epizyme, Inc. |
Carm1 inhibitors and uses thereof
|
|
EP3199181B1
(en)
|
2014-09-22 |
2020-05-06 |
Japan Science and Technology Agency |
Anti-influenza virus agent, and screening method for anti-influenza virus agent
|
|
WO2016046837A1
(en)
|
2014-09-22 |
2016-03-31 |
Cadila Healthcare Limited |
An improved process for preparation of pyrrolo[3,4- c] pyrrole compounds and intermediates thereof
|
|
MA41841A
(fr)
|
2015-03-30 |
2018-02-06 |
Global Blood Therapeutics Inc |
Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
|
|
US20160339022A1
(en)
|
2015-04-17 |
2016-11-24 |
Acetylon Pharmaceuticals Inc. |
Treatment of neuroblastoma with histone deacetylase inhibitors
|
|
US10550150B2
(en)
*
|
2015-05-11 |
2020-02-04 |
Cadila Healthcare Limited |
Short-chain peptides as Kappa (κ) opioid receptors (KOR) agonist
|
|
WO2016196816A1
(en)
|
2015-06-03 |
2016-12-08 |
The University Of North Carolina At Chapel Hill |
Photoredox-catalyzed direct c-h functionalization of arenes
|
|
FI3307271T3
(fi)
|
2015-06-11 |
2023-10-17 |
Agios Pharmaceuticals Inc |
Pyruvaattikinaasin aktivaattorien käyttämisen menetelmä
|
|
US10577321B2
(en)
|
2015-07-08 |
2020-03-03 |
University Of Southern California |
Deoxyuridine triphosphatase inhibitors
|
|
CN105153119B
(zh)
|
2015-09-11 |
2019-01-01 |
广州必贝特医药技术有限公司 |
吡啶嘧啶胺类化合物或吡啶吡啶胺类化合物及其应用
|
|
RU2018112230A
(ru)
|
2015-09-24 |
2019-10-30 |
Ф. Хоффманн-Ля Рош Аг |
Бициклические соединения в качестве ингибиторов atx
|
|
CR20180057A
(es)
*
|
2015-09-24 |
2018-04-02 |
Hoffmann La Roche |
Nuevos compuestos biciclicos como inhibidores duales de atx/ca.
|
|
CN105254628B
(zh)
|
2015-11-13 |
2017-06-23 |
南京华威医药科技开发有限公司 |
吡唑并吡啶类抗肿瘤化合物及其制备方法和应用
|
|
CN105348286B
(zh)
|
2015-11-25 |
2018-12-18 |
中山奕安泰医药科技有限公司 |
一种2-甲基磺酰基-2,4,5,6-四氢吡咯[3,4-c]吡唑苯磺酸盐的制备方法
|
|
EP3452101A2
(en)
|
2016-05-04 |
2019-03-13 |
CureVac AG |
Rna encoding a therapeutic protein
|
|
TWI663160B
(zh)
|
2016-05-12 |
2019-06-21 |
全球血液治療公司 |
用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
|
|
MA44037B1
(fr)
|
2016-06-06 |
2020-03-31 |
Arena Pharm Inc |
Modulateurs du récepteur adrénergique bêta 3 utile dans le traitement ou la prévention de troubles associés à ceux-ci
|
|
CN110191720A
(zh)
|
2016-09-09 |
2019-08-30 |
Tg治疗有限公司 |
用于治疗血液学癌症的抗-CD20抗体、PI 3激酶-δ抑制剂以及抗-PD-1或抗-PD-L1抗体的组合
|
|
TW202332423A
(zh)
|
2016-10-12 |
2023-08-16 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
|
WO2018109277A1
(en)
|
2016-12-14 |
2018-06-21 |
Åbo Akademi University |
Diagnosis of parkinson's disease on the basis of decreased overall translation
|
|
US9744145B1
(en)
|
2017-01-16 |
2017-08-29 |
Macau University Of Science And Technology |
Methods for treating lung cancer
|
|
ES2747768T3
(es)
|
2017-03-20 |
2020-03-11 |
Forma Therapeutics Inc |
Composiciones de pirrolopirrol como activadores de quinasa de piruvato (PKR)
|
|
CN106928222B
(zh)
|
2017-04-25 |
2019-08-23 |
淮阴师范学院 |
一种3-烷基中氮茚衍生物的制备方法
|
|
DK3668513T3
(da)
|
2017-08-15 |
2022-01-10 |
Agios Pharmaceuticals Inc |
Pyruvatkinase-aktiveringsmidler til anvendelse til behandling af blodsygdomme
|
|
WO2019099651A1
(en)
|
2017-11-16 |
2019-05-23 |
Agios Pharmaceuticals, Inc. |
Methods of using deuterated pyruvate kinase activators
|
|
JP7275130B2
(ja)
|
2017-11-22 |
2023-05-17 |
アジオス ファーマシューティカルズ, インコーポレイテッド |
N-(4-(4-(シクロプロピルメチル)ピペラジン-1-カルボニル)フェニル)キノリン-8-スルホンアミドの結晶性形態
|
|
CN111699189B
(zh)
|
2017-12-06 |
2025-02-18 |
艾尼纳制药公司 |
可用于治疗或预防与其相关的心力衰竭和障碍的β-3肾上腺素能受体的调节剂
|
|
SG11202102526QA
(en)
|
2018-09-19 |
2021-04-29 |
Forma Therapeutics Inc |
Inhibiting ubiquitin specific peptidase 9x
|
|
US12053458B2
(en)
|
2018-09-19 |
2024-08-06 |
Novo Nordisk Health Care Ag |
Treating sickle cell disease with a pyruvate kinase R activating compound
|
|
US20210346356A1
(en)
|
2018-09-19 |
2021-11-11 |
Forma Therapeutics, Inc. |
Inhibiting ubiquitin specific peptidase 9x
|
|
ES2989438T3
(es)
|
2018-09-19 |
2024-11-26 |
Novo Nordisk Healthcare Ag |
Activación de la piruvato cinasa R
|
|
PT3880654T
(pt)
|
2018-11-19 |
2022-04-08 |
Global Blood Therapeutics Inc |
Compostos de 2-formil-3-hidroxifeniloximetil capazes de modular hemoglobina
|
|
WO2020191022A1
(en)
|
2019-03-18 |
2020-09-24 |
Forma Therapeutics, Inc. |
Inhibiting ubiquitin specific peptidase 9x
|
|
CN109912610B
(zh)
|
2019-04-04 |
2020-06-23 |
石家庄诚志永华显示材料有限公司 |
有机化合物及其在制备有机电致发光元件中的应用
|