JP2022516469A5 - - Google Patents

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Publication number
JP2022516469A5
JP2022516469A5 JP2021537781A JP2021537781A JP2022516469A5 JP 2022516469 A5 JP2022516469 A5 JP 2022516469A5 JP 2021537781 A JP2021537781 A JP 2021537781A JP 2021537781 A JP2021537781 A JP 2021537781A JP 2022516469 A5 JP2022516469 A5 JP 2022516469A5
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JP
Japan
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JP2021537781A
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Japanese (ja)
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JP2022516469A (ja
JPWO2020139988A5 (https=
JP7553450B2 (ja
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JP2021537781A 2018-12-28 2019-12-27 ユビキチン特異的プロテアーゼ1を阻害するための組成物 Active JP7553450B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862785733P 2018-12-28 2018-12-28
US62/785,733 2018-12-28
PCT/US2019/068648 WO2020139988A1 (en) 2018-12-28 2019-12-27 Compositions for inhibiting ubiquitin specific protease 1

Publications (4)

Publication Number Publication Date
JP2022516469A JP2022516469A (ja) 2022-02-28
JP2022516469A5 true JP2022516469A5 (https=) 2022-12-22
JPWO2020139988A5 JPWO2020139988A5 (https=) 2022-12-22
JP7553450B2 JP7553450B2 (ja) 2024-09-18

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ID=71126375

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JP2021537781A Active JP7553450B2 (ja) 2018-12-28 2019-12-27 ユビキチン特異的プロテアーゼ1を阻害するための組成物

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Country Link
US (1) US20220073525A1 (https=)
EP (1) EP3902802A4 (https=)
JP (1) JP7553450B2 (https=)
CN (1) CN113474346B (https=)
WO (1) WO2020139988A1 (https=)

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Publication number Priority date Publication date Assignee Title
US10189841B2 (en) 2015-11-20 2019-01-29 Forma Therapeutics, Inc. Purinones as ubiquitin-specific protease 1 inhibitors
US20240182481A1 (en) * 2021-02-15 2024-06-06 Tango Therapeutics, Inc. Pyrrolo[3,2-d]pyrimidine compounds and methods of use in the treatment of cancer
MX2023011709A (es) * 2021-04-07 2023-10-12 Forma Therapeutics Inc Inhibidor de la proteasa 1 especifica de ubiquitina (usp1).
EP4321515A4 (en) * 2021-04-09 2025-06-25 Hainan Simcere Zaiming Pharmaceutical Co., Ltd. UBIQUITIN-SPECIFIC PROTEASE-1 INHIBITOR
KR102910851B1 (ko) * 2021-04-21 2026-01-09 장춘 진사이언스 파마슈티컬 씨오., 엘티디. 이미다졸 함유 축합고리계 유도체, 이의 제조방법 및 이의 의약적 용도
WO2022253188A1 (en) * 2021-05-31 2022-12-08 Impact Therapeutics (Shanghai) , Inc Nitrogen-containing fused heteroaromatic bicyclic compounds as usp1 inhibitors and the use thereof
JP2024540921A (ja) * 2021-10-19 2024-11-06 上海瑛派▲薬▼▲業▼有限公司 Usp1阻害剤としての置換トリアゾロヘテロアリール化合物及びその応用
CR20240191A (es) 2021-11-12 2024-09-13 Insilico Medicine Ip Ltd Inhibidores de molécula pequeña de proteasa 1 específica de ubiquitina (usp1) y usos de los mismos
US20250163049A1 (en) * 2022-02-03 2025-05-22 Exelixis, Inc. Fused bicyclic heterocyclyl compounds as usp1 inhibitors
AU2023261809A1 (en) * 2022-04-29 2024-12-05 Asieris Pharmaceuticals (Shanghai) Co., Ltd. Pyrimidine compound, method for preparing same, and pharmaceutical use thereof
WO2024006879A1 (en) * 2022-06-29 2024-01-04 Zentaur Therapeutics Usa Inc. Usp1 inhibitors and uses thereof
WO2024022519A1 (zh) * 2022-07-28 2024-02-01 先声再明医药有限公司 杂环并嘧啶类化合物及其应用
CN119790043A (zh) * 2022-08-26 2025-04-08 海南先声再明医药股份有限公司 三环类化合物及其应用
WO2024078436A1 (zh) * 2022-10-09 2024-04-18 海南先声再明医药股份有限公司 杂环并嘧啶类化合物、药物组合物及其应用
WO2024086790A1 (en) 2022-10-21 2024-04-25 Exelixis, Inc. 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-c]PYRIDINE COMPOUNDS AND DERIVATIVES AS USP1 INHIBITORS
CN120603835A (zh) * 2023-01-20 2025-09-05 杭州英创医药科技有限公司 作为usp1抑制剂的化合物
WO2024233665A1 (en) 2023-05-08 2024-11-14 Tango Therapeutics, Inc. Compounds and their use against cancer
WO2024233605A1 (en) 2023-05-08 2024-11-14 Tango Therapeutics, Inc. Compounds and their use against cancer
WO2024236528A1 (en) * 2023-05-18 2024-11-21 Insilico Medicine Ip Limited Small molecule inhibitors of ubiquitin specific protease 1 (usp1) and uses thereof
WO2025010245A1 (en) 2023-07-06 2025-01-09 Exelixis, Inc. Fused pyrazole derivatives as usp1 inhibitors
CN119930633B (zh) * 2023-11-06 2025-11-18 中国医学科学院药物研究所 一种吡咯并蝶啶酮类泛素特异性蛋白酶1抑制剂及其制备方法、用途和药物组合物
CN119930632B (zh) * 2023-11-06 2025-11-18 中国医学科学院药物研究所 一种三并环类泛素特异性蛋白酶1抑制剂及其制备方法、用途和药物组合物
WO2025102016A1 (en) 2023-11-10 2025-05-15 Vrise Therapeutics, Inc. Novel molecules as inhibitors of dna damage repair pathway
WO2025151705A1 (en) 2024-01-10 2025-07-17 Vrise Therapeutics, Inc. Novel inhibitors of dna damage repair pathway

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AU4035893A (en) * 1991-12-17 1993-07-19 Upjohn Company, The 3-substituted imidazo (1,5-a) and imidazo (1,5-a)-triazolo (1,5-c) quinoxalines and quinazolines with cns activity
EP2170350B1 (en) * 2007-06-21 2013-09-11 Cara Therapeutics, Inc. Substituted imidazoheterocycles
EP2334672B1 (en) * 2008-09-16 2013-11-20 Proximagen Limited 4,5,6,7-Tetrahydroimidazo[4,5-c]pyridine compounds as inhibitors of SSAO
CN101824036A (zh) * 2009-03-05 2010-09-08 上海恒瑞医药有限公司 四氢咪唑并[1,5-a]吡嗪衍生物的盐,其制备方法及其在医药上的应用
US10189841B2 (en) * 2015-11-20 2019-01-29 Forma Therapeutics, Inc. Purinones as ubiquitin-specific protease 1 inhibitors

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