JP2023553835A5 - - Google Patents
Info
- Publication number
- JP2023553835A5 JP2023553835A5 JP2023532465A JP2023532465A JP2023553835A5 JP 2023553835 A5 JP2023553835 A5 JP 2023553835A5 JP 2023532465 A JP2023532465 A JP 2023532465A JP 2023532465 A JP2023532465 A JP 2023532465A JP 2023553835 A5 JP2023553835 A5 JP 2023553835A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkylene
- membered
- independently
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063126722P | 2020-12-17 | 2020-12-17 | |
| US63/126,722 | 2020-12-17 | ||
| US202163279850P | 2021-11-16 | 2021-11-16 | |
| US63/279,850 | 2021-11-16 | ||
| US202163284789P | 2021-12-01 | 2021-12-01 | |
| US63/284,789 | 2021-12-01 | ||
| US202163289014P | 2021-12-13 | 2021-12-13 | |
| US63/289,014 | 2021-12-13 | ||
| PCT/US2021/063721 WO2022133037A1 (en) | 2020-12-17 | 2021-12-16 | Macrocycles and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023553835A JP2023553835A (ja) | 2023-12-26 |
| JP2023553835A5 true JP2023553835A5 (https=) | 2024-12-24 |
Family
ID=82058646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023532465A Pending JP2023553835A (ja) | 2020-12-17 | 2021-12-16 | 大環状化合物およびそれらの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240182487A1 (https=) |
| EP (1) | EP4262796A4 (https=) |
| JP (1) | JP2023553835A (https=) |
| KR (1) | KR20230121773A (https=) |
| AU (1) | AU2021401741A1 (https=) |
| CA (1) | CA3202770A1 (https=) |
| IL (1) | IL303419A (https=) |
| MX (1) | MX2023007162A (https=) |
| PY (1) | PY21110949A (https=) |
| UY (1) | UY39574A (https=) |
| WO (1) | WO2022133037A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2023283476A1 (en) * | 2022-06-08 | 2024-11-14 | Blossomhill Therapeutics, Inc. | Indazole macrocycles and their use |
| CA3258157A1 (en) * | 2022-06-08 | 2023-12-14 | Blossomhill Therapeutics, Inc. | Indazole-Containing Macrocycles and Their Use |
| JP2025524038A (ja) * | 2022-07-27 | 2025-07-25 | 上海和誉生物医薬科技有限公司 | 大環状ｅｇｆｒ阻害剤、その製造方法及び薬学における応用 |
| EP4655304A1 (en) * | 2023-02-22 | 2025-12-03 | Yuhan Corporation | Macrocyclic aminopyridine compounds as egfr inhibitors |
| JP2026507654A (ja) * | 2023-02-22 | 2026-03-04 | ユーハン・コーポレイション | Ｅｇｆｒ阻害剤としての大環状アミノピリジン化合物 |
| KR20250142978A (ko) * | 2023-02-22 | 2025-09-30 | 주식회사유한양행 | Egfr 억제제로서의 마크로시클릭 아미노피리딘 화합물 |
| EP4688750A1 (en) | 2023-04-06 | 2026-02-11 | Pfizer Inc. | Substituted indazole propionic acid derivative compounds and uses thereof as ampk activators |
| AU2024266587A1 (en) * | 2023-05-02 | 2025-09-11 | Blossomhill Therapeutics, Inc. | Egfr inhibitors for treating disease |
| EP4731213A2 (en) * | 2023-06-23 | 2026-04-29 | Blossomhill Therapeutics, Inc. | Combination therapy involving macrocyclic indazole compounds |
| WO2025122911A1 (en) * | 2023-12-07 | 2025-06-12 | Blossomhill Therapeutics, Inc. | Indazole macrocycle polymorphs |
| WO2025122859A1 (en) * | 2023-12-08 | 2025-06-12 | Blossomhill Therapeutics, Inc. | Indazole-based macrocyclic compounds |
| WO2025199438A1 (en) * | 2024-03-22 | 2025-09-25 | Blossomhill Therapeutics, Inc. | 7-azaindazole macrocycles and their use |
| WO2025245175A1 (en) * | 2024-05-22 | 2025-11-27 | Ajax Therapeutics, Inc. | Macrocyclic heteroaromatic inhibitors of jak2 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3062B1 (ar) * | 2010-10-05 | 2017-03-15 | Lilly Co Eli | R)-(e)-2-(4-(2-(5-(1-(3، 5-داي كلورو بيريدين-4-يل)إيثوكسي)-1h-إندازول-3-يل)?ينيل)-1h-بيرازول-1-يل)إيثانول بلوري |
| DK2822953T5 (en) * | 2012-03-06 | 2017-09-11 | Pfizer | Macrocyclic derivatives for the treatment of proliferative diseases |
| EP3333157B1 (en) * | 2015-08-07 | 2020-12-23 | Harbin Zhenbao Pharmaceutical Co., Ltd. | Vinyl compounds as fgfr and vegfr inhibitors |
| CN111269245B (zh) * | 2018-12-04 | 2021-08-27 | 杭州百新生物医药科技有限公司 | 一种环状氨基嘧啶衍生物及其抑制激酶的活性和用途 |
| BR112021012057A2 (pt) * | 2018-12-21 | 2021-10-19 | Revolution Medicines, Inc. | Compostos que participam de ligação cooperativa e usos dos mesmos |
-
2021
- 2021-12-16 WO PCT/US2021/063721 patent/WO2022133037A1/en not_active Ceased
- 2021-12-16 US US18/257,166 patent/US20240182487A1/en active Pending
- 2021-12-16 AU AU2021401741A patent/AU2021401741A1/en active Pending
- 2021-12-16 KR KR1020237021826A patent/KR20230121773A/ko active Pending
- 2021-12-16 MX MX2023007162A patent/MX2023007162A/es unknown
- 2021-12-16 EP EP21907788.0A patent/EP4262796A4/en active Pending
- 2021-12-16 JP JP2023532465A patent/JP2023553835A/ja active Pending
- 2021-12-16 CA CA3202770A patent/CA3202770A1/en active Pending
- 2021-12-16 IL IL303419A patent/IL303419A/en unknown
- 2021-12-17 UY UY0001039574A patent/UY39574A/es unknown
- 2021-12-17 PY PY202121110949A patent/PY21110949A/es unknown
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