JP2009500052A - アブレーションカテーテル - Google Patents

アブレーションカテーテル Download PDF

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Publication number
JP2009500052A
JP2009500052A JP2008517213A JP2008517213A JP2009500052A JP 2009500052 A JP2009500052 A JP 2009500052A JP 2008517213 A JP2008517213 A JP 2008517213A JP 2008517213 A JP2008517213 A JP 2008517213A JP 2009500052 A JP2009500052 A JP 2009500052A
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JP
Japan
Prior art keywords
ablation
carrier assembly
carrier
catheter
control shaft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008517213A
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English (en)
Japanese (ja)
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JP2009500052A5 (enExample
Inventor
ロマン,リチャード,ディー.
アスコンデガイ,アレクサンダー,ジェイ.
クニス,クリストファー,ジー.
フラハーティ,ジェイ.クリストファー
ワーネス,ランデル,エル.
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Medtronic Ablation Frontiers LLC
Original Assignee
Ablation Frontiers Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ablation Frontiers Inc filed Critical Ablation Frontiers Inc
Publication of JP2009500052A publication Critical patent/JP2009500052A/ja
Publication of JP2009500052A5 publication Critical patent/JP2009500052A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A61B2018/00029Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/0016Energy applicators arranged in a two- or three dimensional array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00214Expandable means emitting energy, e.g. by elements carried thereon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00214Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/00267Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • A61B2018/00351Heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • A61B2018/00351Heart
    • A61B2018/00375Ostium, e.g. ostium of pulmonary vein or artery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00821Temperature measured by a thermocouple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00839Bioelectrical parameters, e.g. ECG, EEG
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1435Spiral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1475Electrodes retractable in or deployable from a housing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1861Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument inserted into a body lumen or cavity, e.g. a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N7/02Localised ultrasound hyperthermia
    • A61N7/022Localised ultrasound hyperthermia intracavitary

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Otolaryngology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Plasma & Fusion (AREA)
  • Electromagnetism (AREA)
  • Surgical Instruments (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
JP2008517213A 2005-06-20 2006-06-20 アブレーションカテーテル Pending JP2009500052A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69241605P 2005-06-20 2005-06-20
PCT/US2006/023808 WO2007001981A2 (en) 2005-06-20 2006-06-20 Ablation catheter

Publications (2)

Publication Number Publication Date
JP2009500052A true JP2009500052A (ja) 2009-01-08
JP2009500052A5 JP2009500052A5 (enExample) 2009-08-06

Family

ID=37595714

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008517213A Pending JP2009500052A (ja) 2005-06-20 2006-06-20 アブレーションカテーテル

Country Status (8)

Country Link
US (6) US7850685B2 (enExample)
EP (2) EP2759276A1 (enExample)
JP (1) JP2009500052A (enExample)
CN (1) CN101309651B (enExample)
AU (1) AU2006262447A1 (enExample)
CA (1) CA2612679A1 (enExample)
IL (1) IL188882A0 (enExample)
WO (1) WO2007001981A2 (enExample)

Cited By (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013078587A (ja) * 2011-10-04 2013-05-02 Biosense Webster (Israel) Ltd 螺旋状の電極組立体を有するマッピングカテーテル
JP2013532552A (ja) * 2010-07-30 2013-08-19 ボストン サイエンティフィック サイムド,インコーポレイテッド 腎臓神経切除用の複数の可撓性を備えたワイヤの高周波電極
JP2013540563A (ja) * 2010-10-25 2013-11-07 メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ 腎臓神経調節のための多電極アレイを有するカテーテル装置、ならびに関連するシステムおよび方法
JP2014501551A (ja) * 2010-10-28 2014-01-23 クック メディカル テクノロジーズ エルエルシー アブレーションデバイス
WO2014083698A1 (ja) * 2012-11-30 2014-06-05 株式会社グツドマン アブレーションカテーテル
JP2014522702A (ja) * 2011-07-22 2014-09-08 ボストン サイエンティフィック サイムド,インコーポレイテッド ヘリカル・ガイド内に配置可能な神経調節要素を有する神経調節システム
KR101450041B1 (ko) * 2012-06-21 2014-10-15 주식회사 두배시스템 의료용 카테터의 센터링기구
JP2015524310A (ja) * 2012-08-02 2015-08-24 エシコン・エンド−サージェリィ・インコーポレイテッドEthicon Endo−Surgery,Inc. 可撓性のある拡張可能な電極及びパルスパワーを管腔内送達する方法
JP2016507349A (ja) * 2013-03-08 2016-03-10 セント・ジュード・メディカル・エイトリアル・フィブリレーション・ディヴィジョン・インコーポレーテッド マルチ電極アレイ・カテーテル用バスケット
JP2016508820A (ja) * 2013-03-04 2016-03-24 シーエスエー メディカル, インコーポレイテッド 低温スプレーカテーテル
JP2016168214A (ja) * 2015-03-13 2016-09-23 テルモ株式会社 医療デバイス
JP2016529982A (ja) * 2013-08-09 2016-09-29 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 拡張式カテーテルならびに関連する製造方法及び使用方法
JP2016195826A (ja) * 2010-04-26 2016-11-24 メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ 腎神経調節のためのカテーテル装置
JP2017029727A (ja) * 2015-07-29 2017-02-09 バイオセンス・ウエブスター・(イスラエル)・リミテッドBiosense Webster (Israel), Ltd. 二重バスケットカテーテル
JP2017077479A (ja) * 2013-01-16 2017-04-27 セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド 可撓性の高密度マッピング・カテーテル・チップおよびオンボード高密度マッピング電極を備える可撓性のアブレーション・カテーテル・チップ
JP2017148524A (ja) * 2013-02-25 2017-08-31 インター・ノバ株式会社 生体環境を監視するためのカテーテル
US9855096B2 (en) 2012-05-11 2018-01-02 Medtronic Ardian Luxembourg S.A.R.L. Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods
JP2018503490A (ja) * 2015-02-03 2018-02-08 上▲海▼魅▲麗▼▲緯▼叶医▲療▼科技有限公司 螺旋構造の高周波アブレーションカテーテル及びその機器
JP2018515226A (ja) * 2015-05-13 2018-06-14 上▲海▼魅▲麗▼▲緯▼叶医▲療▼科技有限公司 密着調節ワイヤを有する波紋型高周波アブレーションカテーテル及びその機器
JP2018126564A (ja) * 2010-05-12 2018-08-16 シファメド・ホールディングス・エルエルシー 低い外形の電極組立体
CN109199578A (zh) * 2017-07-06 2019-01-15 韦伯斯特生物官能(以色列)有限公司 利用多个电极的温度控制的短持续时间消融
JP2019510588A (ja) * 2016-04-08 2019-04-18 セント・ジュード・メディカル,カーディオロジー・ディヴィジョン,インコーポレイテッド マッピング可変ループ・カテーテル・ハンドル
JP2019093148A (ja) * 2018-12-25 2019-06-20 清明 本間 カテーテルおよびカテーテルシステム
JP2019527121A (ja) * 2016-07-29 2019-09-26 アクソン セラピーズ, インク.Axon Therapies, Inc. 内臓神経アブレーションによる心不全の治療の為のデバイス、システム及び方法
US10492729B2 (en) 2007-05-23 2019-12-03 St. Jude Medical, Cardiology Division, Inc. Flexible high-density mapping catheter tips and flexible ablation catheter tips with onboard high-density mapping electrodes
JP2020513202A (ja) * 2017-04-05 2020-05-07 ナショナル・ユニバーシティ・オブ・アイルランド・ガルウェイ 植え込み型医療装置
JPWO2020196141A1 (enExample) * 2019-03-26 2020-10-01
JPWO2021065875A1 (enExample) * 2019-09-30 2021-04-08
JP2021062210A (ja) * 2019-10-10 2021-04-22 バイオセンス・ウエブスター・(イスラエル)・リミテッドBiosense Webster (Israel), Ltd. バルーン表面の温度測定によるバルーンカテーテルアブレーション電極のタッチ表示
JP2021511103A (ja) * 2018-01-18 2021-05-06 ファラパルス,インコーポレイテッド フォーカルアブレーションのためのシステム、デバイス、および方法
JP2021522021A (ja) * 2018-05-01 2021-08-30 マゼラン・バイオメディカル インコーポレーテッド 介入手術のための装置の操縦、追跡および誘導のためのシステムおよび方法
JP2022501112A (ja) * 2018-09-20 2022-01-06 ファラパルス,インコーポレイテッド 心内膜組織へのパルス電界アブレーションエネルギーの送達のためのシステム、装置、および方法
JP2022017223A (ja) * 2015-12-01 2022-01-25 サイマップ メディカル (スーチョウ),エルティーディー 動脈の壁を支配する機能的な神経をマッピングするためのシステムと方法、そのための3dマッピング、およびカテーテル
JP2022512378A (ja) * 2018-12-11 2022-02-03 ニューレント メディカル リミテッド 療法的鼻神経変調のためのシステムおよび方法
JP2022046452A (ja) * 2020-09-10 2022-03-23 バイオセンス・ウエブスター・(イスラエル)・リミテッド フレックス回路及び表面装着型電極カテーテル
JP2022070836A (ja) * 2020-09-10 2022-05-13 バイオセンス・ウエブスター・(イスラエル)・リミテッド 表面装着型電極カテーテル
US11413090B2 (en) 2020-01-17 2022-08-16 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
US11433220B2 (en) 2017-07-07 2022-09-06 St. Jude Medical, Cardiology Division, Inc. Layered high density electrode mapping catheter
JP2022539155A (ja) * 2019-06-28 2022-09-07 ニューレント メディカル リミテッド 標的化療法的鼻神経変調のためのシステムおよび方法
US11446075B2 (en) 2014-06-04 2022-09-20 Csa Medical, Inc. Method and system for consistent, repeatable, and safe cryospray treatment of airway tissue
WO2023276080A1 (ja) * 2021-06-30 2023-01-05 日本ライフライン株式会社 カテーテル
US11642063B2 (en) 2018-08-23 2023-05-09 St. Jude Medical, Cardiology Division, Inc. Curved high density electrode mapping catheter
US11712296B2 (en) 2017-12-17 2023-08-01 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
US11751939B2 (en) 2018-01-26 2023-09-12 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
US11806073B2 (en) 2019-06-20 2023-11-07 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
US11864826B2 (en) 2015-02-05 2024-01-09 Axon Therapies, Inc. Devices and methods for treatment of heart failure by splanchnic nerve ablation
JP2024517666A (ja) * 2021-04-26 2024-04-23 パルス バイオサイエンシズ インコーポレイテッド 周方向アブレーションデバイス及び方法
US12121357B2 (en) 2015-10-21 2024-10-22 St. Jude Medical, Cardiology Division, Inc. High density electrode mapping catheter

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US6634363B1 (en) 1997-04-07 2003-10-21 Broncus Technologies, Inc. Methods of treating lungs having reversible obstructive pulmonary disease
US7992572B2 (en) 1998-06-10 2011-08-09 Asthmatx, Inc. Methods of evaluating individuals having reversible obstructive pulmonary disease
US7921855B2 (en) 1998-01-07 2011-04-12 Asthmatx, Inc. Method for treating an asthma attack
US7198635B2 (en) 2000-10-17 2007-04-03 Asthmatx, Inc. Modification of airways by application of energy
US8181656B2 (en) 1998-06-10 2012-05-22 Asthmatx, Inc. Methods for treating airways
US6702811B2 (en) 1999-04-05 2004-03-09 Medtronic, Inc. Ablation catheter assembly with radially decreasing helix and method of use
US20060095032A1 (en) 1999-11-16 2006-05-04 Jerome Jackson Methods and systems for determining physiologic characteristics for treatment of the esophagus
US20040215235A1 (en) 1999-11-16 2004-10-28 Barrx, Inc. Methods and systems for determining physiologic characteristics for treatment of the esophagus
US8251070B2 (en) 2000-03-27 2012-08-28 Asthmatx, Inc. Methods for treating airways
US7104987B2 (en) 2000-10-17 2006-09-12 Asthmatx, Inc. Control system and process for application of energy to airway walls and other mediums
US8974446B2 (en) 2001-10-11 2015-03-10 St. Jude Medical, Inc. Ultrasound ablation apparatus with discrete staggered ablation zones
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
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JP7574442B2 (ja) 2021-06-30 2024-10-28 日本ライフライン株式会社 カテーテル
WO2023276080A1 (ja) * 2021-06-30 2023-01-05 日本ライフライン株式会社 カテーテル
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WO2007001981A2 (en) 2007-01-04
EP1895927A2 (en) 2008-03-12
US20140288552A1 (en) 2014-09-25
US9468495B2 (en) 2016-10-18
CA2612679A1 (en) 2007-01-04
EP2759276A1 (en) 2014-07-30
CN101309651A (zh) 2008-11-19
AU2006262447A1 (en) 2007-01-04
US20150157402A1 (en) 2015-06-11
US20130116688A1 (en) 2013-05-09
US20070083194A1 (en) 2007-04-12
US8979841B2 (en) 2015-03-17
US20110106074A1 (en) 2011-05-05
US8337492B2 (en) 2012-12-25
US20170027640A1 (en) 2017-02-02
EP1895927A4 (en) 2011-03-09
WO2007001981A3 (en) 2007-04-05
US8771267B2 (en) 2014-07-08
IL188882A0 (en) 2008-04-13
CN101309651B (zh) 2011-12-07
US7850685B2 (en) 2010-12-14

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