EA010508B1 - Способ прицельного воздействия на определенные популяции клеток с помощью конъюгатов из майтансиноида и агента клеточного связывания, соединенных через нерасщепляемый линкер, конъюгаты и способы получения таких конъюгатов - Google Patents

Способ прицельного воздействия на определенные популяции клеток с помощью конъюгатов из майтансиноида и агента клеточного связывания, соединенных через нерасщепляемый линкер, конъюгаты и способы получения таких конъюгатов Download PDF

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Publication number
EA010508B1
EA010508B1 EA200600752A EA200600752A EA010508B1 EA 010508 B1 EA010508 B1 EA 010508B1 EA 200600752 A EA200600752 A EA 200600752A EA 200600752 A EA200600752 A EA 200600752A EA 010508 B1 EA010508 B1 EA 010508B1
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EA
Eurasian Patent Office
Prior art keywords
binding agent
maytansinoid
cell binding
conjugate
antibody
Prior art date
Application number
EA200600752A
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English (en)
Russian (ru)
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EA200600752A1 (ru
Inventor
Рита Стивс
Роберт Лутц
Рави Чари
Хонгсхенг Ксие
Елена Ковтун
Original Assignee
Иммьюноджен, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34467962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA010508(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Иммьюноджен, Инк. filed Critical Иммьюноджен, Инк.
Publication of EA200600752A1 publication Critical patent/EA200600752A1/ru
Publication of EA010508B1 publication Critical patent/EA010508B1/ru

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
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EA200600752A 2003-10-10 2004-10-12 Способ прицельного воздействия на определенные популяции клеток с помощью конъюгатов из майтансиноида и агента клеточного связывания, соединенных через нерасщепляемый линкер, конъюгаты и способы получения таких конъюгатов EA010508B1 (ru)

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KR101476082B1 (ko) 2014-12-23
US8563509B2 (en) 2013-10-22
EP1689846B1 (en) 2013-03-27
US20080171865A1 (en) 2008-07-17
AU2004282491B2 (en) 2010-12-23
IL246605A (en) 2017-08-31
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AU2004282491A1 (en) 2005-04-28
JP2014177463A (ja) 2014-09-25
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HK1244452A1 (zh) 2018-08-10
CN103223174A (zh) 2013-07-31
CA2542128A1 (en) 2005-04-28
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KR20140033003A (ko) 2014-03-17
SI1689846T1 (en) 2013-06-28
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US8163888B2 (en) 2012-04-24
KR20060130552A (ko) 2006-12-19
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US20170226220A1 (en) 2017-08-10
KR101573124B1 (ko) 2015-12-01
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CN107198778A (zh) 2017-09-26
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US20140154804A1 (en) 2014-06-05
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AU2010212291A1 (en) 2010-09-02
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IL173625A (en) 2016-07-31
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