DK3205654T3 - MACROCYCLIC COMPOUNDS AS TRK-KINASE INHIBITORS - Google Patents
MACROCYCLIC COMPOUNDS AS TRK-KINASE INHIBITORS Download PDFInfo
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- DK3205654T3 DK3205654T3 DK17163978.4T DK17163978T DK3205654T3 DK 3205654 T3 DK3205654 T3 DK 3205654T3 DK 17163978 T DK17163978 T DK 17163978T DK 3205654 T3 DK3205654 T3 DK 3205654T3
- Authority
- DK
- Denmark
- Prior art keywords
- fluoro
- hexaazapentacyclo
- heptaen
- oxa
- compound
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- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
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- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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| US34676710P | 2010-05-20 | 2010-05-20 | |
| US201061426716P | 2010-12-23 | 2010-12-23 | |
| EP15150036.0A EP2918588B1 (en) | 2010-05-20 | 2011-05-13 | Macrocyclic compounds as TRK kinase inhibitors |
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| DK15150036.0T DK2918588T3 (en) | 2010-05-20 | 2011-05-13 | Macrocyclic compounds as TRK kinase inhibitors |
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| DK15150036.0T DK2918588T3 (en) | 2010-05-20 | 2011-05-13 | Macrocyclic compounds as TRK kinase inhibitors |
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| CA2863892C (en) * | 2012-03-06 | 2016-08-30 | Pfizer Inc. | Macrocyclic derivatives for the treatment of proliferative diseases |
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