DK0740668T3 - Tetracykliske derivater, fremgangsmåde til deres fremstilling og deres anvendelse - Google Patents

Tetracykliske derivater, fremgangsmåde til deres fremstilling og deres anvendelse

Info

Publication number
DK0740668T3
DK0740668T3 DK95907565T DK95907565T DK0740668T3 DK 0740668 T3 DK0740668 T3 DK 0740668T3 DK 95907565 T DK95907565 T DK 95907565T DK 95907565 T DK95907565 T DK 95907565T DK 0740668 T3 DK0740668 T3 DK 0740668T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
tetracyclic derivatives
tetracyclic
derivatives
Prior art date
Application number
DK95907565T
Other languages
Danish (da)
English (en)
Inventor
Alain Claude-Marie Daugan
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10749089&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0740668(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of DK0740668T3 publication Critical patent/DK0740668T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK95907565T 1994-01-21 1995-01-19 Tetracykliske derivater, fremgangsmåde til deres fremstilling og deres anvendelse DK0740668T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9401090A GB9401090D0 (en) 1994-01-21 1994-01-21 Chemical compounds
PCT/EP1995/000183 WO1995019978A1 (en) 1994-01-21 1995-01-19 Tetracyclic derivatives, process of preparation and use

Publications (1)

Publication Number Publication Date
DK0740668T3 true DK0740668T3 (da) 1999-05-03

Family

ID=10749089

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95907565T DK0740668T3 (da) 1994-01-21 1995-01-19 Tetracykliske derivater, fremgangsmåde til deres fremstilling og deres anvendelse

Country Status (48)

Country Link
US (5) US5859006A (cs)
EP (1) EP0740668B1 (cs)
JP (3) JP3808095B2 (cs)
KR (1) KR100357411B1 (cs)
CN (2) CN1045777C (cs)
AP (1) AP556A (cs)
AT (1) ATE169018T1 (cs)
AU (2) AU689205B2 (cs)
BG (1) BG62733B1 (cs)
BR (1) BR9506559C8 (cs)
CA (1) CA2181377C (cs)
CO (1) CO4340684A1 (cs)
CZ (1) CZ286566B6 (cs)
DE (2) DE69503753T2 (cs)
DK (1) DK0740668T3 (cs)
EE (1) EE03231B1 (cs)
EG (1) EG25852A (cs)
ES (1) ES2122543T3 (cs)
FI (1) FI113176B (cs)
GB (1) GB9401090D0 (cs)
HR (1) HRP950023B1 (cs)
HU (1) HU222494B1 (cs)
IL (1) IL112384A (cs)
IN (1) IN183942B (cs)
IS (1) IS1888B (cs)
LU (1) LU91017I2 (cs)
LV (1) LV11690B (cs)
MA (1) MA23433A1 (cs)
MX (1) MX9602904A (cs)
MY (1) MY114663A (cs)
NL (1) NL300124I2 (cs)
NO (2) NO306465B1 (cs)
NZ (1) NZ279199A (cs)
OA (1) OA10584A (cs)
PE (1) PE49495A1 (cs)
PL (1) PL179744B1 (cs)
RO (1) RO117794B1 (cs)
RU (1) RU2142463C1 (cs)
SA (1) SA95150475B1 (cs)
SG (1) SG49184A1 (cs)
SI (1) SI0740668T1 (cs)
SK (1) SK280879B6 (cs)
SV (1) SV1995000002A (cs)
TN (1) TNSN95004A1 (cs)
TW (1) TW378210B (cs)
UY (1) UY23893A1 (cs)
WO (1) WO1995019978A1 (cs)
ZA (1) ZA95424B (cs)

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SG49184A1 (en) 1998-05-18
ATE169018T1 (de) 1998-08-15
LU91017I2 (fr) 2003-05-26
AU707055B2 (en) 1999-07-01
RO117794B1 (ro) 2002-07-30
MY114663A (en) 2002-12-31
PE49495A1 (es) 1996-01-10
MX9602904A (es) 1997-12-31
NL300124I2 (nl) 2003-11-03
US6784179B2 (en) 2004-08-31
AP9500712A0 (en) 1995-01-31
US5859006A (en) 1999-01-12
EP0740668B1 (en) 1998-07-29
FI962927A7 (fi) 1996-07-19
AU7391298A (en) 1998-08-20
AP556A (en) 1996-11-07
IS4252A (is) 1995-07-22
CO4340684A1 (es) 1996-07-30
LV11690A (lv) 1997-02-20
BG100727A (bg) 1997-02-28
NO2003002I2 (no) 2005-03-21
NO963015D0 (no) 1996-07-19
HRP950023A2 (en) 1998-04-30
GB9401090D0 (en) 1994-03-16
IL112384A0 (en) 1995-03-30
JP2009102386A (ja) 2009-05-14
CN1224720A (zh) 1999-08-04
CZ211696A3 (en) 1997-06-11
US6127542A (en) 2000-10-03
MA23433A1 (fr) 1995-10-01
AU1574895A (en) 1995-08-08
JP4347125B2 (ja) 2009-10-21
DE69503753T2 (de) 1999-01-21
EP0740668A1 (en) 1996-11-06
CN1045777C (zh) 1999-10-20
IN183942B (cs) 2000-05-20
JP3808095B2 (ja) 2006-08-09
EG25852A (en) 2012-09-10
AU689205B2 (en) 1998-03-26
US20020119976A1 (en) 2002-08-29
SV1995000002A (es) 1995-10-04
HK1013286A1 (en) 1999-08-20
CZ286566B6 (cs) 2000-05-17
SI0740668T1 (en) 1999-02-28
NO2003002I1 (no) 2003-01-22
IS1888B (is) 2003-09-01
DE69503753D1 (de) 1998-09-03

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