CY1111682T1 - Μεθοδοι και τροποι για την αποκτηση τροποποιημενων φαινοτυπων - Google Patents

Μεθοδοι και τροποι για την αποκτηση τροποποιημενων φαινοτυπων

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Publication number
CY1111682T1
CY1111682T1 CY20111100648T CY111100648T CY1111682T1 CY 1111682 T1 CY1111682 T1 CY 1111682T1 CY 20111100648 T CY20111100648 T CY 20111100648T CY 111100648 T CY111100648 T CY 111100648T CY 1111682 T1 CY1111682 T1 CY 1111682T1
Authority
CY
Cyprus
Prior art keywords
nucleotide sequence
consecutive nucleotides
methods
sequence
sense
Prior art date
Application number
CY20111100648T
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English (en)
Inventor
Peter Michael Waterhouse
Ming-Bo Wang
Michael Wayne Graham
Original Assignee
Commonwealth Scientific And Industrial Research Organisation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26735688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1111682(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Commonwealth Scientific And Industrial Research Organisation filed Critical Commonwealth Scientific And Industrial Research Organisation
Publication of CY1111682T1 publication Critical patent/CY1111682T1/el

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8283Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8282Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance

Abstract

Παρέχονται μέθοδοι και τρόποι για την ελάττωση της φαινοτυπικής έκφρασης ενός νουκλεϊκού οξέος του ενδιαφέροντος σε ευκαρυωτικά κύτταρα, συγκεκριμένα σε φυτικά κύτταρα, με την εισαγωγή χιμαιρικών γονιδίων που κωδικοποιούν μόρια RNA ορθής και αντίθετης φοράς που κατευθύνονται έναντι του νουκλεϊκού οξέος στόχου, τα οποία είναι ικανά να σχηματίζουν δίκλωνες περιοχές RNA με ζευγάρωμα βάσεων μεταξύ περιοχών των νουκλεοτιδικών αλληλουχιών ορθής και αντίθετης φοράς ή με την εισαγωγή των ίδιων των μορίων RNA. Κατά προτίμηση, τα μόρια RNA περιέχουν ταυτόχρονα νουκλεοτιδικές αλληλουχίες ορθής και αντίθετης φοράς.
CY20111100648T 1998-04-08 2011-07-05 Μεθοδοι και τροποι για την αποκτηση τροποποιημενων φαινοτυπων CY1111682T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5676798A 1998-04-08 1998-04-08
US12773598A 1998-08-03 1998-08-03
EP99910592.7A EP1068311B2 (en) 1998-04-08 1999-04-07 Methods and means for obtaining modified phenotypes

Publications (1)

Publication Number Publication Date
CY1111682T1 true CY1111682T1 (el) 2015-10-07

Family

ID=26735688

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100648T CY1111682T1 (el) 1998-04-08 2011-07-05 Μεθοδοι και τροποι για την αποκτηση τροποποιημενων φαινοτυπων

Country Status (14)

Country Link
EP (4) EP2267138B1 (el)
JP (1) JP5015373B2 (el)
CN (1) CN1202246C (el)
AT (1) ATE507299T1 (el)
AU (1) AU760041B2 (el)
CA (1) CA2325344C (el)
CY (1) CY1111682T1 (el)
DE (1) DE69943389D1 (el)
DK (1) DK1068311T3 (el)
ES (1) ES2624549T3 (el)
NZ (1) NZ507093A (el)
PT (1) PT1068311E (el)
SI (1) SI1068311T1 (el)
WO (1) WO1999053050A1 (el)

Families Citing this family (513)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
KR101085210B1 (ko) 1998-03-20 2011-11-21 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 유전자 발현 조절방법
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
US7019195B1 (en) 1998-05-26 2006-03-28 Syngenta Participations Ag Method for conferring resistance or tolerance aganist furovirus, potyvirus, tospovirus, and cucomovirus to plant cells
AR020078A1 (es) * 1998-05-26 2002-04-10 Syngenta Participations Ag Metodo para alterar la expresion de un gen objetivo en una celula de planta
US7005423B1 (en) 1999-07-02 2006-02-28 Devgen Nv Characterization of gene function using double stranded RNA inhibition
GB9827152D0 (en) * 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
US6759574B1 (en) 1998-11-05 2004-07-06 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Plants having enhanced gall resistance and methods and compositions for producing same
AU2008202208C1 (en) * 1999-01-30 2014-04-24 Alnylam Pharmaceuticals, Inc. Method and medicament for inhibiting the expression of a defined gene
DE19956568A1 (de) * 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
US6987025B1 (en) 1999-02-11 2006-01-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Dwf4 polynucleotides, polypeptides and uses thereof
WO2000063364A2 (en) 1999-04-21 2000-10-26 American Home Products Corporation Methods and compositions for inhibiting the function of polynucleotide sequences
TR200103088T2 (tr) * 1999-05-10 2002-05-21 Syngenta Participations Ag Viral gen ekspresyonunun düzenlenmesi.
GB9918061D0 (en) 1999-07-30 1999-10-06 Univ Bath Modified plants
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US7531718B2 (en) 1999-08-26 2009-05-12 Monsanto Technology, L.L.C. Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
BR0013607A (pt) 1999-08-26 2002-04-30 Calgene Llc Sequências de ácidos nucléicos e processos de uso para a produção de plantas com ácidos graxos poliinsaturados modificados
US7067722B2 (en) 1999-08-26 2006-06-27 Monsanto Technology Llc Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
AU1086501A (en) 1999-10-15 2001-04-30 Carnegie Institution Of Washington Rna interference pathway genes as tools for targeted genetic interference
US7829693B2 (en) 1999-11-24 2010-11-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a target gene
DE10100586C1 (de) 2001-01-09 2002-04-11 Ribopharma Ag Verfahren zur Hemmung der Expression eines Ziegens
US20050229272A1 (en) * 1999-12-30 2005-10-13 Monica Driscoll Compositions and methods for gene silencing
US8273866B2 (en) 2002-02-20 2012-09-25 Merck Sharp & Dohme Corp. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
US7833992B2 (en) 2001-05-18 2010-11-16 Merck Sharpe & Dohme Conjugates and compositions for cellular delivery
US8202979B2 (en) 2002-02-20 2012-06-19 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
US20070026394A1 (en) 2000-02-11 2007-02-01 Lawrence Blatt Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies
US7491805B2 (en) 2001-05-18 2009-02-17 Sirna Therapeutics, Inc. Conjugates and compositions for cellular delivery
AU2001240375A1 (en) * 2000-03-17 2001-10-03 Benitec Australia Limited Genetic silencing
CA2404890C (en) 2000-03-30 2013-11-19 Whitehead Institute For Biomedical Research Rna sequence-specific mediators of rna interference
AU5016301A (en) 2000-04-18 2001-10-30 Commw Scient Ind Res Org Method of modifying the content of cottonseed oil
JP2004512020A (ja) 2000-06-23 2004-04-22 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 組換え構築物ならびにこれを遺伝子発現を減少させる際に用いる方法
CN1330753C (zh) 2000-08-30 2007-08-08 北卡罗莱纳州立大学 含有可改变蛋白含量的分子诱导物的转基因植物
US7517975B2 (en) 2000-09-26 2009-04-14 Pioneer Hi-Bred International, Inc. Nucleotide sequences mediating male fertility and method of using same
CA2427347C (en) 2000-10-31 2011-01-18 Commonwealth Scientific And Industrial Research Organisation Method and means for producing barley yellow dwarf virus resistant cereal plants
US7122719B2 (en) * 2000-11-03 2006-10-17 Monsanto Technology Llc Method of imparting disease resistance to plants by reducing polyphenol oxidase activities
US7888499B2 (en) 2000-11-09 2011-02-15 Commonwealth Scientific And Industrial Research Organization Barley with reduced SSII activity and starch containing products with a reduced amylopectin content
BRPI0115814B8 (pt) 2000-12-01 2021-05-25 Europaeisches Laboratorium Fuer Molekularbiologie Embl moléculas de rna de filamento duplo, seu método de preparação e composição farmacêutica compreendendo as mesmas
BR0115782A (pt) 2000-12-08 2004-01-20 Commonwealh Scient And Ind Res Modificação de expressão de gene de sacarose sintase em tecido de planta e usos
JP2004532616A (ja) * 2000-12-28 2004-10-28 ジョンソン・アンド・ジョンソン・リサーチ・ピー・ティー・ワイ・リミテッド 二本鎖rna仲介遺伝子抑制
US7423142B2 (en) 2001-01-09 2008-09-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of anti-apoptotic genes
US8546143B2 (en) 2001-01-09 2013-10-01 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a target gene
US7767802B2 (en) 2001-01-09 2010-08-03 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of anti-apoptotic genes
CA2429397C (en) 2001-01-26 2014-06-03 Commonwealth Scientific And Industrial Research Organisation Methods and means for producing efficient silencing construct using recombinational cloning
EP1229134A3 (en) 2001-01-31 2004-01-28 Nucleonics, Inc Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
US7109165B2 (en) 2001-05-18 2006-09-19 Sirna Therapeutics, Inc. Conjugates and compositions for cellular delivery
WO2003070912A2 (en) * 2001-06-06 2003-08-28 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
US20050148530A1 (en) 2002-02-20 2005-07-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US9994853B2 (en) 2001-05-18 2018-06-12 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
CA2451654A1 (en) 2001-06-22 2003-01-03 Ceres, Inc. Chimeric histone acetyltransferase polypeptides
AUPR621501A0 (en) 2001-07-06 2001-08-02 Commonwealth Scientific And Industrial Research Organisation Delivery of ds rna
BR0211111A (pt) 2001-07-12 2004-06-22 Univ Massachusetts Molécula de ácido nucleico isolada, vetor, célula hospedeira, transgene, precursor de rna engenheirado, animal transgênico não humano, e, método de induzir a interferência de ácido ribonucleico de um gene alvo em uma célula
US8022272B2 (en) 2001-07-13 2011-09-20 Sungene Gmbh & Co. Kgaa Expression cassettes for transgenic expression of nucleic acids
US7612194B2 (en) 2001-07-24 2009-11-03 Monsanto Technology Llc Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof
EP1279737A1 (en) 2001-07-27 2003-01-29 Coöperatieve Verkoop- en Productievereniging, van Aardappelmeel en Derivaten AVEBE B.A. Transformation method for obtaining marker-free plants
US20030198627A1 (en) 2001-09-01 2003-10-23 Gert-Jan Arts siRNA knockout assay method and constructs
US7456335B2 (en) 2001-09-03 2008-11-25 Basf Plant Science Gmbh Nucleic acid sequences and their use in methods for achieving pathogen resistance in plants
EP1437936A4 (en) 2001-09-27 2005-10-12 Pioneer Hi Bred Int PHYTATE POLYNUCLEOTIDES AND METHOD FOR THEIR USE
WO2003031632A1 (en) * 2001-10-05 2003-04-17 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw An efficient system for rna silencing
DE10163098B4 (de) 2001-10-12 2005-06-02 Alnylam Europe Ag Verfahren zur Hemmung der Replikation von Viren
US7745418B2 (en) 2001-10-12 2010-06-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting viral replication
US7294504B1 (en) 2001-12-27 2007-11-13 Allele Biotechnology & Pharmaceuticals, Inc. Methods and compositions for DNA mediated gene silencing
DE10202419A1 (de) 2002-01-22 2003-08-07 Ribopharma Ag Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens
EP3415625A1 (en) 2002-02-01 2018-12-19 Life Technologies Corporation Double-stranded oligonucleotides
US20060009409A1 (en) 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
AU2003207708A1 (en) 2002-02-20 2003-09-09 Sirna Therapeutics, Inc. Rna interference mediated inhibition of map kinase genes
US9657294B2 (en) 2002-02-20 2017-05-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US7534934B2 (en) 2002-02-20 2009-05-19 J.R. Simplot Company Precise breeding
BRPI0307791B1 (pt) 2002-02-20 2020-08-11 J.R. Simplot Company Métodos para modificar característica de planta selecionada
US9181551B2 (en) 2002-02-20 2015-11-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
DE10212892A1 (de) * 2002-03-20 2003-10-09 Basf Plant Science Gmbh Konstrukte und Verfahren zur Regulation der Genexpression
DE10212893A1 (de) * 2002-03-20 2003-10-16 Basf Plant Science Gmbh Verfahren zum Erhöhen des Ölgehaltes in Pflanzen
US7566813B2 (en) 2002-03-21 2009-07-28 Monsanto Technology, L.L.C. Nucleic acid constructs and methods for producing altered seed oil compositions
EP1484959A4 (en) 2002-03-21 2005-08-31 Monsanto Technology Llc NUCLEIC ACID CONSTRUCTS AND METHODS FOR PRODUCING MODIFIED SEED OIL COMPOSITIONS
US7166771B2 (en) 2002-06-21 2007-01-23 Monsanto Technology Llc Coordinated decrease and increase of gene expression of more than one gene using transgenic constructs
EP1352960A1 (en) * 2002-04-12 2003-10-15 Viruvation B.V. Antiviral therapy on the basis of RNA interference
US20040180438A1 (en) 2002-04-26 2004-09-16 Pachuk Catherine J. Methods and compositions for silencing genes without inducing toxicity
CA2524569C (en) 2002-05-03 2013-10-22 Duke University A method of regulating gene expression
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
US20040029283A1 (en) * 2002-06-21 2004-02-12 Fillatti Joanne J. Intron double stranded RNA constructs and uses thereof
ATE405658T1 (de) 2002-07-26 2008-09-15 Basf Plant Science Gmbh Neue selektionsverfahren
US7205454B2 (en) 2002-07-31 2007-04-17 Bayer Bioscience N.V. Corn root preferential promoters and uses thereof
SI3222724T1 (sl) 2002-08-05 2019-03-29 Silence Therapeutics Gmbh Nadaljnje nove oblike molekul interferenčne RNA
US20060211637A1 (en) * 2002-08-06 2006-09-21 Intradigm Corporation Methods of down regulating target gene expression in vivo by introduction of interfering rna
AU2003246349B2 (en) 2002-08-07 2011-02-03 Basf Plant Science Gmbh Nucleic acid sequences encoding proteins associated with abiotic stress response
US7956176B2 (en) 2002-09-05 2011-06-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US7476777B2 (en) 2002-09-17 2009-01-13 Ceres, Inc. Biological containment system
US7078234B2 (en) 2002-12-18 2006-07-18 Monsanto Technology Llc Maize embryo-specific promoter compositions and methods for use thereof
CA2505776C (en) 2002-12-19 2013-04-02 Bayer Cropscience Gmbh Plant cells and plants which synthesize a starch with an increased final viscosity
AU2003300394A1 (en) * 2002-12-24 2004-07-22 Genpath Pharmaceuticals, Incorporated In vivo methods for validating the role of a tumor maintenance gene
BR0317754A (pt) 2002-12-24 2005-11-22 Cropdesign Nv Plantas tendo caracterìsticas de crescimento modificadas e método para produzi-las
EP2078753A3 (en) 2002-12-26 2010-12-15 Syngenta Participations AG Cell proliferation-related polypeptides and uses therefor
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US7129089B2 (en) 2003-02-12 2006-10-31 E. I. Du Pont De Nemours And Company Annexin and P34 promoters and use in expression of transgenic genes in plants
CN1750752A (zh) * 2003-02-19 2006-03-22 联邦科学和工业研究组织 使用短dsRNA序列在植物中进行有效的基因沉默
CN1836045B (zh) 2003-03-28 2012-05-09 孟山都技术有限公司 用于早期种子发育的新型植物启动子
WO2004087755A2 (en) 2003-04-01 2004-10-14 Cropdesign N.V. Plant haemoglobin
US7786349B2 (en) 2003-04-09 2010-08-31 Bayer Bioscience N.V. Methods and means for increasing the tolerance of plants to stress conditions
BRPI0409363A (pt) * 2003-04-09 2006-04-25 Bayer Bioscience Nv métodos e meios para o aumento da toleráncia de plantas a condições de tensão
WO2006032707A2 (en) 2004-09-24 2006-03-30 Basf Plant Science Gmbh Plant cells and plants with increased tolerance to environmental stress
IL155783A (en) 2003-05-05 2010-11-30 Technion Res & Dev Foundation Multicellular systems of multi-potential embryonic human stem cells and cancer cells and their use
NZ544391A (en) 2003-06-06 2009-06-26 Arborgen Llc Plant transformation and selection
AU2004249889B2 (en) 2003-06-23 2011-04-21 BASF Agricultural Solutions Seed US LLC Methods and means for delaying seed shattering in plants
JP4923171B2 (ja) 2003-06-30 2012-04-25 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガニゼイション 分枝酵素の活性を改変した小麦、ならびにそれから得たデンプンおよびデンプン含有品
CN1852985A (zh) 2003-08-01 2006-10-25 巴斯福植物科学有限公司 产生精细化学品的方法
WO2005017157A1 (en) 2003-08-15 2005-02-24 Commonwealth Scientific And Industrial Research Organisation (Csiro) Methods and means for altering fiber characteristics in fiber-producing plants
IL157538A0 (en) 2003-08-21 2004-03-28 Bar Ilan Res & Dev Company Ltd Plant resistant to cytoplasm-feeding parasites
WO2005035769A2 (en) 2003-10-09 2005-04-21 E. I. Du Pont De Nemours And Company Gene silencing by using micro-rna molecules
EP2302062A1 (en) 2003-10-20 2011-03-30 CropDesign N.V. Identification of E2F target genes and uses thereof
CN101128475B (zh) 2003-11-12 2012-06-20 纳幕尔杜邦公司 适用于改变产油植物及酵母中多不饱和脂肪酸水平的△15脂肪酸去饱和酶
AU2004304665B2 (en) 2003-12-24 2009-03-12 Novo Nordisk A/S Transgenic non-human mammal comprising a polynucleotide encoding human or humanized C5aR
US7855323B2 (en) 2004-02-10 2010-12-21 Monsanto Technology Llc Recombinant DNA for gene suppression
US20060075515A1 (en) 2004-08-11 2006-04-06 Luethy Michael H Enhanced zein reduction in transgenic corn seed
AR047598A1 (es) 2004-02-10 2006-01-25 Monsanto Technology Llc Semilla de maiz transgenica con mayor contenido de aminoacidos
US7683237B2 (en) 2004-02-10 2010-03-23 Monsanto Technology Llc Maize seed with synergistically enhanced lysine content
CA2554212A1 (en) 2004-02-10 2005-08-25 Sirna Therapeutics, Inc. Rna interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional sina)
ZA200607843B (en) * 2004-02-23 2008-06-25 Israel State Engrafted plants resistant to viral diseases and methods of producing same
US7622301B2 (en) 2004-02-24 2009-11-24 Basf Plant Science Gmbh Compositions and methods using RNA interference for control of nematodes
EP1735009A4 (en) 2004-03-12 2011-03-30 Alnylam Pharmaceuticals Inc RNAI AGENTS TARGETING THE VASCULAR ENDOTHELIUM GROWTH FACTOR (VEGF)
US20060041961A1 (en) 2004-03-25 2006-02-23 Abad Mark S Genes and uses for pant improvement
US8049069B2 (en) 2004-03-31 2011-11-01 Commonwealth Scientific And Industrial Research Organisation Genes involved in plant fibre development
US20060021087A1 (en) 2004-04-09 2006-01-26 Baum James A Compositions and methods for control of insect infestations in plants
WO2005100575A2 (en) 2004-04-14 2005-10-27 Bayer Bioscience N.V. Rice pollen-specific promoters and uses thereof
CA2884237C (en) 2004-04-22 2020-09-08 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CA2557532A1 (en) 2004-04-23 2005-11-10 Angela M. Christiano Inhibition of hairless protein mrna
CN102102106B (zh) 2004-04-23 2013-05-29 塞雷斯公司 改良植物特征的方法
US10508277B2 (en) 2004-05-24 2019-12-17 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
EP2080769A3 (en) 2004-07-02 2010-12-01 Metanomics GmbH Process for the production of fine chemicals
US8680062B2 (en) 2004-07-06 2014-03-25 Deliversir Ltd. System for delivering therapeutic agents into living cells and cells nuclei
US20060075522A1 (en) 2004-07-31 2006-04-06 Jaclyn Cleveland Genes and uses for plant improvement
CA2573986C (en) 2004-08-02 2013-11-26 Basf Plant Science Gmbh Transcription termination sequence and use thereof
US7659444B2 (en) 2004-08-13 2010-02-09 Basf Plant Science Gmbh Compositions and methods using RNA interference for control of nematodes
CN100395334C (zh) * 2004-08-24 2008-06-18 暨南大学 抑制bcl-2基因表达的siRNA双链
FI20041204A0 (fi) 2004-09-16 2004-09-16 Riikka Lund Menetelmät immuunivälitteisiin sairauksiin liittyvien uusien kohdegeenien hyödyntämiseksi
CA2940718C (en) 2004-09-24 2019-06-18 J.R. Simplot Company Gene silencing
US20060247197A1 (en) 2004-10-04 2006-11-02 Van De Craen Marc Method for down-regulating gene expression in fungi
EP2163632A1 (en) 2004-10-05 2010-03-17 SunGene GmbH Constitutive expression cassettes for regulation of plant expression
AU2005295948A1 (en) 2004-10-12 2006-04-27 The Rockefeller University MicroRNAs
US7429692B2 (en) 2004-10-14 2008-09-30 Ceres, Inc. Sucrose synthase 3 promoter from rice and uses thereof
WO2006047495A2 (en) 2004-10-21 2006-05-04 Venganza Inc Methods and materials for conferring resistance to pests and pathogens of plants
WO2006046148A2 (en) 2004-10-25 2006-05-04 Devgen Nv Rna constructs
EP1655364A3 (en) 2004-11-05 2006-08-02 BASF Plant Science GmbH Expression cassettes for seed-preferential expression in plants
EP2163631B1 (en) 2004-11-25 2013-05-22 SunGene GmbH Expression cassettes for guard cell-preferential expression in plants
EP1666599A3 (en) 2004-12-04 2006-07-12 SunGene GmbH Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants
EP2072620B1 (en) 2004-12-08 2013-05-08 SunGene GmbH Expression casstettes for vascular tissue-preferential expression in plants
EP1669456A3 (en) 2004-12-11 2006-07-12 SunGene GmbH Expression cassettes for meristem-preferential expression in plants
EP2199304A1 (en) 2004-12-17 2010-06-23 Metanomics GmbH Process for the control of production of fine chemicals
US7335760B2 (en) 2004-12-22 2008-02-26 Ceres, Inc. Nucleic acid sequences encoding zinc finger proteins
EP1831376A1 (en) 2004-12-28 2007-09-12 Pioneer Hi-Bred International, Inc. Improved grain quality through altered expression of seed proteins
EP2489726A3 (en) 2005-01-12 2012-11-28 Monsanto Technology LLC Genes and uses for plant improvement
EP1841870B1 (en) 2005-01-14 2013-09-04 University Of Guelph Nitrogen-regulated sugar sensing gene and protein and modulation thereof
FR2881143B1 (fr) 2005-01-27 2010-12-17 Librophyt Systeme de production de terpenoides dans les plantes
CA2596600A1 (en) 2005-02-09 2006-08-17 Basf Plant Science Gmbh Expression cassettes for regulation of expression in monocotyledonous plants
ATE526421T1 (de) 2005-02-14 2011-10-15 Univ Iowa Res Found Verfahren und reagenzien zur behandlung und diagnose von altersbedingter makuladegeneration
EP1851317B1 (en) 2005-02-23 2011-10-26 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes
BRPI0607378A2 (pt) 2005-02-26 2010-03-23 Basf Plant Science Gmbh cassetes de expressço, seqÜÊncia nucleotÍdica isolada, vetor, cÉlula hospedeira transgÊnica ou organismo nço humano, cÉlula de planta ou planta transgÊnica, mÉtodos para identificar e/ou isolar uma seqÜÊncia nucleotÍdica reguladora da transcriÇço, para prover ou produzir um cassete de expressço transgÊnica, e para prover uma seqÜÊncia nucleotÍdica reguladora de transcriÇço sintÉtica, e, seqÜÊncia reguladora de transcriÇço sintÉtica
EP2045327B8 (en) 2005-03-08 2012-03-14 BASF Plant Science GmbH Expression enhancing intron sequences
EP1707632A1 (de) 2005-04-01 2006-10-04 Bayer CropScience GmbH Phosphorylierte waxy-Kartoffelstärke
ATE552343T1 (de) 2005-04-19 2012-04-15 Basf Plant Science Gmbh Endosperm-spezifische expression und/oder expression in keimenden embryos monokotyledoner pflanzen
US7790873B2 (en) 2005-05-10 2010-09-07 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
AR053269A1 (es) 2005-05-16 2007-04-25 Monsanto Technology Llc Plantas y semillas de maiz con mejoramiento de asparagina y proteina
US20060272057A1 (en) 2005-05-25 2006-11-30 Pioneer Hi-Bred International, Inc. Methods for improving crop plant architecture and yield
EP1907546A2 (en) 2005-05-31 2008-04-09 Devgen N.V. Rnai for control of insects and arachnids
EP1731037A1 (en) 2005-06-04 2006-12-13 Bayer CropScience AG Increase of stress tolerance by application of neonicotinoids on plants engineered to be stress tolerant
DE602006008459D1 (de) 2005-06-15 2009-09-24 Bayer Bioscience Nv Pflanzen gegen hypoxische bedingungen
ATE495265T1 (de) 2005-06-23 2011-01-15 Basf Plant Science Gmbh Verbesserte verfahren zur herstellung stabil transformierter und fruchtbarer buntmais-pflanzen
CA2621874C (en) 2005-09-08 2014-12-16 Chromatin Inc. Plants modified with mini-chromosomes
CA2622660C (en) 2005-09-16 2017-11-07 Devgen Nv Transgenic plant-based methods for plant pests using rnai
PL2431473T3 (pl) 2005-09-16 2017-05-31 Monsanto Technology Llc Sposoby genetycznej kontroli inwazji owadów u roślin i kompozycje do tego przeznaczone
CA2620387C (en) 2005-09-20 2018-09-18 Basf Plant Science Gmbh Methods for controlling gene expression using ta-sirna
CA2626304C (en) 2005-10-20 2015-07-14 Commonwealth Scientific And Industrial Research Organisation Cereals with altered dormancy
EP1941059A4 (en) 2005-10-28 2010-11-03 Alnylam Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR INHIBITING THE EXPRESSION OF THE HUNTINGTIN GENE
WO2007056326A2 (en) 2005-11-04 2007-05-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of nav1.8 gene
WO2007054522A1 (en) 2005-11-08 2007-05-18 Cropdesign N.V. Plants having improved growth characteristics and a method for making the same
WO2007054441A2 (de) 2005-11-08 2007-05-18 Basf Plant Science Gmbh Verwendung von armadillo-repeat (arm1)-polynukleotiden zum erreichen einer pathogenresistenz in pflanzen
US20100069461A1 (en) 2005-11-09 2010-03-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of factor v leiden mutant gene
CN101356279A (zh) 2005-11-10 2009-01-28 先锋高级育种国际公司 Dof(具有一指的dna结合)序列和使用方法
AU2006320596B2 (en) 2005-12-01 2013-02-07 Cropdesign N.V. Plants having improved growth characteristics and methods for making the same
EP2377939A3 (en) 2006-01-12 2012-01-18 deVGen N.V. Transgenic plant-based methods for plant pests using RNAi
US8906876B2 (en) 2006-01-12 2014-12-09 Devgen Nv Methods for controlling pests using RNAi
JP5474356B2 (ja) 2006-01-12 2014-04-16 デブジェン エヌブイ RNAiを使用する害虫を制御する方法
US8178751B2 (en) 2006-01-12 2012-05-15 Basf Plant Science Gmbh Use of stomatin (STM1) polynucleotides for achieving a pathogen resistance in plants
CA2637254A1 (en) 2006-01-17 2007-07-26 Biolex Therapeutics, Inc. Compositions and methods for humanization and optimization of n-glycans in plants
EP1991568A2 (en) 2006-02-09 2008-11-19 Pioneer Hi-Bred International Inc. Genes for enhancing nitrogen utilization efficiency in crop plants
BRPI0707626A2 (pt) 2006-02-10 2011-05-10 Monsanto Technology Llc identificaÇço e uso de genes alvos para o controle de nematàides parasitas de plantas
CA2836368C (en) 2006-02-13 2020-04-07 Monsanto Technology Llc Method for managing crop pest resistance
CN101421406B (zh) 2006-02-13 2016-08-31 孟山都技术有限公司 用于产生改变的种子油组成的核酸构建体和方法
WO2007115168A2 (en) 2006-03-31 2007-10-11 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of eg5 gene
US8642838B2 (en) 2006-03-31 2014-02-04 Basf Plant Science Gmbh Plants having enhanced yield-related traits and a method for making the same
EP2090662A3 (en) 2006-04-05 2012-10-31 Metanomics GmbH Process for the production of a fine chemical
EP2007799A2 (en) 2006-04-19 2008-12-31 Pioneer Hi-Bred International, Inc. Isolated polynucleotide molecules corresponding to mutant and wild-type alleles of the maize d9 gene and methods of use
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7691824B2 (en) 2006-04-28 2010-04-06 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a gene from the JC virus
NZ572666A (en) 2006-05-11 2010-11-26 Alnylam Pharmaceuticals Inc Compositions comprising double stranded rna and methods for inhibiting expression of the pcsk9 gene
US20070271629A1 (en) 2006-05-17 2007-11-22 Pioneer Hi-Bred International, Inc. Artificial plant minichromosomes
EP2023937B1 (en) 2006-05-19 2011-10-12 Alnylam Pharmaceuticals Inc. Rnai modulation of aha and therapeutic uses thereof
WO2007137220A2 (en) 2006-05-22 2007-11-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of ikk-b gene
US20090241218A1 (en) 2006-05-30 2009-09-24 Cropdesign N.V. Plants having enhanced yield-related traits and a method for making the same
US9315818B2 (en) 2006-06-07 2016-04-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Plant expression constructs and methods of utilizing same
US8536429B2 (en) 2006-07-12 2013-09-17 Commonwealth Scientific And Industrial Research Organisation Polynucleotides encoding a NAX2 polypeptide and methods for enhancing salinity tolerance in plants
NZ574046A (en) 2006-07-13 2012-09-28 Univ Iowa Res Found Methods and reagents for treatment and diagnosis of vascular disorders and age-related macular degeneration
EP2054516B1 (en) 2006-08-02 2014-01-08 CropDesign N.V. Plants having improved characteristics and a method for making the same
ES2558133T3 (es) 2006-08-02 2016-02-02 Cropdesign N.V. Plantas transformadas con el polipéptido SYT que tienen el rendimiento aumentado en estrés abiótico y procedimiento de producción de las mismas
CN101600798A (zh) * 2006-08-31 2009-12-09 孟山都技术有限公司 相位型小rna
CA2666821C (en) 2006-08-31 2015-05-26 Monsanto Technology Llc Method for producing transgenic corn plants in a single container
EP2069380B1 (en) 2006-09-18 2014-11-12 Alnylam Pharmaceuticals Inc. Rnai modulation of scap and therapeutic uses thereof
US20090209478A1 (en) 2006-09-21 2009-08-20 Tomoko Nakayama Compositions and methods for inhibiting expression of the hamp gene
EP2390339B1 (en) 2006-10-23 2013-07-31 E. I. du Pont de Nemours and Company Delta-8 desaturases and their use in making polyunsaturated fatty acids
US8350119B2 (en) 2006-11-24 2013-01-08 Cropdesign N.V. Transgenic plants comprising as transgene A class I TCP or Clavata 1 (CLV1) or CAH3 polypeptide having increased seed yield and a method for making the same
CN101195821A (zh) 2006-12-04 2008-06-11 中国科学院上海生命科学研究院 利用RNAi技术改良植物抗虫性的方法
WO2008067840A1 (en) 2006-12-08 2008-06-12 Swetree Technologies Ab Plants having improved growth characteristics and method for making the same
CN101578371B (zh) 2007-01-11 2014-04-16 拜尔作物科学公司 亚基因组特异性等位基因在棉花中的差异表达及其用途
EP2057273A2 (en) 2007-01-15 2009-05-13 BASF Plant Science GmbH Use of subtilisin (rnr9) polynucleotides for achieving a pathogen resistance in plants
DE112008000275T5 (de) 2007-01-31 2009-12-31 Basf Plant Science Gmbh Pflanzen mit verbesserten Ertragsmerkmalen und/oder erhöhter Resistenz gegen abiotischen Stress und Verfahren zu ihrer Herstellung
CN101686641B (zh) 2007-02-05 2014-05-07 新加坡国立大学 推定的细胞激动素受体和其应用方法
CA2674494A1 (en) 2007-02-06 2008-08-14 Basf Plant Science Gmbh Compositions and methods using rna interference for control of nematodes
CA2675207A1 (en) 2007-02-12 2008-07-21 E. I. Du Pont De Nemours And Company Production of arachidonic acid in oilseed plants
CA2675926A1 (en) 2007-02-16 2008-08-21 Basf Plant Science Gmbh Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants
DK2129680T3 (en) 2007-03-21 2015-08-10 Brookhaven Science Ass Llc COMBINED hairpin ANTISENSE COMPOSITIONS AND METHODS FOR MODULATING EXPRESSION OF
PE20090064A1 (es) 2007-03-26 2009-03-02 Novartis Ag Acido ribonucleico de doble cadena para inhibir la expresion del gen e6ap humano y composicion farmaceutica que lo comprende
WO2008121604A2 (en) 2007-03-29 2008-10-09 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a gene from the ebola
US8158858B2 (en) 2007-04-04 2012-04-17 E I Du Pont De Nemours And Company Soybean promoters and flower-preferred expression thereof in transgenic plants
US7642436B2 (en) 2007-04-13 2010-01-05 Ball Horticultural Company Petunia mutant allele
CA2584934A1 (en) 2007-04-17 2008-10-17 University Of Guelph Nitrogen-regulated sugar sensing gene and protein and modulation thereof
EP2137302B1 (en) 2007-04-19 2014-06-25 Monsanto Technology, LLC Corn plants and seed enhanced for asparagine and protein
EP2069509B1 (en) 2007-05-03 2013-09-18 BASF Plant Science GmbH Plants having enhanced yield-related traits and a method for making the same
US8957280B2 (en) 2007-05-03 2015-02-17 E. I. Du Pont De Nemours And Company Delta-5 desaturases and their use in making polyunsaturated fatty acids
US8759612B2 (en) 2007-05-17 2014-06-24 E. I. Du Pont De Nemours And Company Soybean promoters LTP2 and flower-preferred expression thereof in transgenic plants
US20080295202A1 (en) 2007-05-17 2008-11-27 Zhongsen Li Soybean promoters SC194 and flower-preferred expression thereof in transgenic plants
DE112008001453T5 (de) 2007-05-22 2010-04-29 Basf Plant Science Gmbh Pflanzenzellen und Pflanzen mit erhöhter Toleranz und/oder Resistenz gegenüber Umweltstress und erhöhter Biomasseproduktion-KO
CN101772575B (zh) 2007-05-23 2015-03-11 先正达参股股份有限公司 多核苷酸标志物
MX2009012596A (es) 2007-05-24 2009-12-08 Du Pont Genes de diacilglicerol aciltransferasa de yarrowia lipolytica para la produccion mejorada de lipidos de almacenamiento de semillas y para los perfiles alterados de acidos grasos en el frijol de soya.
CA2687211A1 (en) 2007-05-25 2008-12-04 Cropdesign N.V. Yield enhancement in plants by modulation of maize alfins
US20100240597A1 (en) 2007-06-15 2010-09-23 Arkansas State University Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same
US8710206B2 (en) 2007-06-15 2014-04-29 E. I. Du Pont De Nemours And Company Soybean EF1A promoter and its use in constitutive expression of transgenic genes in plants
WO2009003977A2 (en) 2007-06-29 2009-01-08 Basf Plant Science Gmbh Plants having enhanced yield-related traits and a method for making the same
EP2164966A2 (en) 2007-07-05 2010-03-24 Novartis Ag Dsrna for treating viral infection
ES2440265T3 (es) 2007-07-20 2014-01-28 Basf Plant Science Gmbh Plantas que tienen un aumento de características relacionadas con el rendimiento y un método para elaboración de las mismas
AR067748A1 (es) 2007-07-31 2009-10-21 Basf Plant Science Gmbh Plantas que tienen rasgos mejorados relacionados con el rendimiento y un metodo para obtenerlas
CA2697186A1 (en) 2007-07-31 2009-02-05 Basf Plant Science Gmbh Plants having enhanced yield-related traits and a method for making the same
MX2010001347A (es) 2007-08-03 2010-03-01 Pioneer Hi Bred Int Secuencias de nucleotidos msca1 que afectan la fertilidad vegetal masculina y metodo para usar las mismas.
CN101821375B (zh) 2007-08-13 2013-07-10 联邦科学技术研究组织 具有低水平大麦醇溶蛋白的大麦
AU2008286701B2 (en) 2007-08-14 2015-02-12 Commonwealth Scientific And Industrial Research Organisation Improved gene silencing methods
CN101815432A (zh) 2007-08-29 2010-08-25 纳幕尔杜邦公司 涉及编码核苷二磷酸激酶(ndk)多肽及其同源物的基因的用于修改植物根构造的方法
JP2010536388A (ja) 2007-08-30 2010-12-02 ザ ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ 樹状細胞マーカーおよびその使用法
WO2009034188A1 (en) 2007-09-14 2009-03-19 Basf Plant Science Gmbh Plants having increased yield-related traits and a method for making the same
CA2703827A1 (en) 2007-10-29 2009-05-07 Basf Plant Science Gmbh Plants having enhanced yield-related traits and a method for making the same
BRPI0820042B1 (pt) 2007-11-12 2020-05-19 North Carolina State University método de obtenção de uma planta de tabaco, ou célula ou parte desta, tendo níveis reduzidos de nornicotina, produto de tabaco, método para fabricar um produto de tabaco, polinucleotídeo isolado, cassete de expressão, polipetpídeo isolado e método de obtenção de uma planta, ou parte de planta desta, do gênero nicotiana
US8129586B2 (en) 2007-11-20 2012-03-06 Pioneer Hi-Bred International, Inc. Maize ethylene signaling genes and modulation of same for improved stress tolerance in plants
MX2010005578A (es) 2007-11-20 2010-06-02 Du Pont Plantas con alteraciones en la arquitectura radicular, constructos y metodos relacionados que requieren genes que codifican polipeptidos de cinasa rica en repeticiones de leucina y homologos de estos.
AR071545A1 (es) 2007-11-26 2010-06-30 Basf Plant Science Gmbh Plantas con rasgos aumentados relacionados con el rendimiento y un metodo para desarrollarlas
UA113829C2 (uk) 2007-11-27 2017-03-27 Коммонвелс Сайнтіфік Енд Індастріал Рісерч Організейшн Генетично модифікована рослина зі збільшеним потенціалом продуктивності
EP2245159A2 (en) 2007-12-10 2010-11-03 Alnylam Pharmaceuticals Inc. Compositions and methods for inhibiting expression of factor vii gene
AU2008339968A1 (en) 2007-12-20 2009-07-02 Basf Plant Science Gmbh Plants having enhanced yield-related traits and a method for making the same
US8809626B2 (en) 2007-12-21 2014-08-19 Keygene N.V. Trichome specific promoters
EP2240587A2 (en) 2007-12-21 2010-10-20 BASF Plant Science GmbH Plants with increased yield (ko nue)
AU2008344053B2 (en) 2007-12-28 2014-03-27 Swetree Technologies Ab Woody plants having improved growth charateristics and method for making the same using transcription factors
CN101965405B (zh) 2008-01-25 2014-03-05 巴斯夫植物科学有限公司 具有增强的产量相关性状的植物和用于制备该植物的方法
AU2009208640B2 (en) 2008-01-31 2014-11-20 National Institute For Biological Sciences Plants having altered growth and/or development and a method for making the same
AU2009221899B2 (en) 2008-03-04 2015-09-03 Washington State University Compositions and methods for differential regulation of fatty acid unsaturation in membrane lipids and seed oil
WO2009111658A2 (en) 2008-03-05 2009-09-11 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of eg5 and vegf genes
EP2100962A1 (en) 2008-03-12 2009-09-16 Biogemma Plants having improved resistance to pathogens
BRPI0910576A2 (pt) 2008-04-16 2015-08-04 Basf Plant Science Gmbh Métodos para intensificar e/ou aumentar características relacionadas com rendimento em plantas, e para a produção de uma planta transgênica apresentando rendimento aumentado, construção, usos de uma construção e de um ácido nucleico que codifica um polipeptídeo de ornitina descarboxilase, planta, parte de planta ou célula de planta, planta transgênica, partes colhíveis de uma planta, e, produtos.
EP2274431A1 (en) 2008-05-05 2011-01-19 BASF Plant Science GmbH Plants having enhanced yield-related traits and a method for making the same
US7964774B2 (en) 2008-05-14 2011-06-21 Monsanto Technology Llc Plants and seeds of spring canola variety SCV384196
EP2620501A3 (en) 2008-05-23 2013-10-02 E. I. du Pont de Nemours and Company DGAT genes from oleaginous organisms for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
CA2990650C (en) 2008-05-23 2021-02-09 Pioneer Hi-Bred International, Inc. Novel dgat genes for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
US9121074B2 (en) 2008-05-26 2015-09-01 Bayer Cropscience N.V. Gossypium hirsutum plants with increased fiber strength comprising a fiber strength allele spanning the GLUC1.1A gene from Gossypium barbadense
CN103834683A (zh) 2008-06-20 2014-06-04 巴斯夫植物科学有限公司 具有增强的产量相关性状的植物和产生所述植物的方法
MX2010013622A (es) 2008-06-26 2011-02-15 Basf Plant Science Gmbh Plantas que tienen rasgos mejorados relacionados con el rendimiento y un metodo para obtenerlas.
CA2729303A1 (en) 2008-06-30 2010-01-14 Angioblast Systems, Inc. Treatment of eye diseases and excessive neovascularization using a combined therapy
AU2009265701A1 (en) 2008-07-04 2010-01-07 Basf Plant Science Gmbh Plants having enhanced yield-related traits and a method for making the same by overexpressing a polynucleotide encoding a TFL1-like protein
MX2011000483A (es) 2008-07-17 2011-02-24 Basf Plant Science Gmbh Plantas que tienen rasgos mejorados relacionados con el rendimiento y un metodo para producir las mismas.
ES2603530T3 (es) 2008-07-21 2017-02-28 Commonwealth Scientific And Industrial Research Organisation Aceite de semilla de algodón mejorado y usos
CN102144033A (zh) 2008-07-31 2011-08-03 巴斯夫植物科学有限公司 具有修饰的生长特征的植物及其制备方法
AU2009284263B2 (en) 2008-08-20 2015-04-09 Basf Plant Science Gmbh Plants having enhanced yield-related traits and a method for making the same
US8318693B2 (en) 2008-09-02 2012-11-27 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of mutant EGFR gene
CN102224247B (zh) 2008-09-24 2016-09-28 巴斯夫植物科学有限公司 具有改良的产量相关性状的植物和用于制备该植物的方法
EP3109321B1 (en) 2008-09-25 2019-05-01 Alnylam Pharmaceuticals, Inc. Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene
US8329989B2 (en) 2008-09-29 2012-12-11 Monsanto Technology Llc Soybean transgenic event MON87705 and methods for detection thereof
NO2937418T3 (el) 2008-10-20 2018-03-17
CN102197137A (zh) 2008-10-30 2011-09-21 先锋国际良种公司 对谷氨酰胺合成酶(gs)进行操作以改善高等植物中的氮利用效率和籽粒产量
US20120005770A1 (en) 2008-11-03 2012-01-05 Swetree Technologies Ab Vegetabile material, plants and a method of producing a plant having altered lignin properties
MX2011004785A (es) 2008-11-12 2011-06-16 Basf Plant Science Gmbh Plantas que tienen mejor tolerancia al estres abiotico y/o mejores rasgos relacionados con el rendimiento y un metodo para producirlas.
BRPI0922553A2 (pt) 2008-12-03 2013-05-07 Basf Plant Science Gmbh mÉtodo para aumentar a tolerÂncia a estresse abiàtico e/ou para aumentar uma caracterÍstica relacionada ao rendimento em uma planta, construto, planta, cÉlula de planta ou parte da mesma, incluindo sementes, partes cultivÁveis da dita planta, produtos derivados de dita planta e/ou de ditas partes cultivÁveis, mÉtodo para a produÇço de plantas transgÊnicas, uso de um construto ou de um Ácido nucleico, molÉcula de Ácido nucleico isolada, e, polipeptÍdeo isolado
CA2743707A1 (en) 2008-12-04 2010-06-10 Pioneer Hi-Bred International, Inc. Methods and compositions for enhanced yield by targeted expression of knotted1
US8497075B2 (en) 2008-12-09 2013-07-30 Novartis Ag Methods of identifying a modulator that inhibits the binding between Epstein-Barr virus induced receptor 2 and cholesterol derived ligands
CA2746514C (en) 2008-12-10 2018-11-27 Alnylam Pharmaceuticals, Inc. Gnaq targeted dsrna compositions and methods for inhibiting expression
AU2009328306A1 (en) 2008-12-17 2011-07-14 Basf Plant Science Gmbh Plants having enhanced yield-related traits and/or abiotic stress tolerance and a method for making the same
US8653080B2 (en) 2009-01-14 2014-02-18 Salk Institute For Biological Studies Methods for screening and compounds that protect against amyloid diseases
EP2845903A3 (en) 2009-01-28 2015-06-10 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
US8309530B2 (en) 2009-02-04 2012-11-13 Washington State University Compositions and methods for modulating ghrelin-mediated conditions
BRPI1008725A2 (pt) 2009-02-25 2016-03-08 Basf Plant Science Co Gmbh métodos para intensificar e melhorar características relacionadas ao rendimento em plantas com relação às plantas de controle, e para a produção de uma planta transgênica, construto, usos do construto, de um ácido nucleico, e de uma sequência de ácido nucleic, planta, parte da planta ou célula da planta, planta transgênica, partes colhíveis, produtos, molécula de ácido nucleico isolada, e, polipeptídeo isolado
WO2010099341A1 (en) 2009-02-26 2010-09-02 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of mig-12 gene
WO2010101818A1 (en) 2009-03-02 2010-09-10 Pioneer Hi-Bred International, Inc. Nac transcriptional activators involved in abiotic stress tolerance
NZ594995A (en) 2009-03-12 2013-06-28 Alnylam Pharmaceuticals Inc LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF HUMAN KINESIN FAMILY MEMBER 11 (Eg5) AND VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) GENES
BRPI1006273A2 (pt) 2009-03-20 2019-09-24 Basf Plant Science Gmbh " vetor de expressão isolado, vegetal transgênico, método para produção de um vegetal transgênico e método para conferir resistência contra nematoide a um vegetal "
AU2010225469B2 (en) 2009-03-20 2016-05-05 Mesoblast, Inc. Production of reprogrammed pluripotent cells
EP2419510B1 (en) 2009-04-14 2015-09-16 Pioneer Hi-Bred International Inc. Modulation of acc synthase improves plant yield under low nitrogen conditions
CA2758824A1 (en) 2009-04-17 2010-10-21 Basf Plant Science Company Gmbh Plant promoter operable in endosperm and uses thereof
MX2011011076A (es) 2009-04-20 2011-11-18 Monsanto Technology Llc Resistencia a multiples virus en plantas.
CA3020943A1 (en) 2009-04-22 2010-10-28 Basf Plant Science Company Gmbh Whole seed specific promoter
CN102459613A (zh) 2009-04-29 2012-05-16 巴斯夫植物科学有限公司 具有增强的产量相关性状的植物及其制备方法
EP2424994B1 (en) 2009-04-29 2015-08-12 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
CN102439032B (zh) 2009-05-04 2015-07-22 先锋国际良种公司 通过调节ap2转录因子增加植物中的产量
AU2010244546A1 (en) 2009-05-06 2011-12-01 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and/or enhanced abiotic stress tolerance and a method for making the same
EP2440664B1 (en) 2009-06-08 2021-04-21 Nunhems B.V. Drought tolerant plants
US20120047603A1 (en) 2009-06-09 2012-02-23 Allen Stephen M Drought tolerant plants and related constructs and methods involving genes encoding fatty acid desaturase family polypeptides
MX2011013421A (es) 2009-06-15 2012-03-16 Alnylam Pharmaceuticals Inc Arnds formulado con lipido de direccionamiento del gen pcsk9.
WO2010145846A1 (en) 2009-06-15 2010-12-23 Bayer Bioscience N.V. Nicotiana benthamiana plants deficient in xylosyltransferase activity
US9051567B2 (en) 2009-06-15 2015-06-09 Tekmira Pharmaceuticals Corporation Methods for increasing efficacy of lipid formulated siRNA
WO2011006717A2 (en) 2009-06-19 2011-01-20 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and a method for making the same
CA2764073A1 (en) 2009-06-30 2011-01-20 E. I. Du Pont De Nemours And Company Plant seeds with altered storage compound levels, related constructs and methods involving genes encoding cytosolic pyrophosphatase
EP2451958A1 (en) 2009-07-10 2012-05-16 BASF Plant Science Company GmbH Expression cassettes for endosperm-specific expression in plants
CA2768571A1 (en) 2009-07-24 2011-01-27 Pioneer Hi-Bred International, Inc. The use of dimerization domain component stacks to modulate plant architecture
AP3574A (en) 2009-08-14 2016-02-08 Alnylam Pharmaceuticals Inc Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus
CN102686604A (zh) 2009-08-19 2012-09-19 巴斯夫植物科学有限公司 具有增强的产量相关性状的植物和用于产生该植物的方法
US8440891B2 (en) 2009-09-22 2013-05-14 Board of Trustees of the University of Akransas, N.A. Rice cultivar CL 142-AR
EP3118320A1 (en) 2009-09-25 2017-01-18 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
CA2772983A1 (en) 2009-09-25 2011-03-31 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and a method for making the same
BR112012007516A2 (pt) 2009-10-02 2015-09-15 Pioneer Hi Bred Int ácido nucléico isolado, plantas , células vegetais, métodos de redução de produção de etileno em uma planta, de aumento de produtividade em uma planta e de aumento de tolerância à aridez, cassete de expressão e semente
US8440892B2 (en) 2009-10-15 2013-05-14 Board Of Trustees Of The University Of Arkansas, N.A. Rice cultivar CL 181-AR
BR112012009566A2 (pt) 2009-10-22 2017-05-09 Basf Plant Science Co Gmbh plantas que possuem caracteristicas relativas a rendimento aprimoradas e método de sua elaboração
AR078829A1 (es) 2009-10-30 2011-12-07 Du Pont Plantas y semillas con niveles alterados de compuesto de almacenamiento, construcciones relacionadas y metodos relacionados con genes que codifican proteinas similares a las aldolasas bacterianas de la clase ii del acido 2,4- dihidroxi-hept-2-eno-1,7-dioico
CN104651323A (zh) 2009-11-13 2015-05-27 巴斯夫植物科学有限公司 具有增强的产量相关性状的植物和用于产生该植物的方法
BR112012013156A2 (pt) 2009-12-03 2017-06-13 Basf Plant Science Co Gmbh cassete de expressão, vetor, célula horpedeira, tecido de planta transgênica e método para a produção de um tecido de planta transgênica
WO2011067745A2 (en) 2009-12-06 2011-06-09 Rosetta Green Ltd. Compositions and methods for enhancing plants resistance to abiotic stress
EP2510090A1 (en) 2009-12-09 2012-10-17 BASF Plant Science Company GmbH Methods for increasing the resistance of plants to fungi by silencing the fungal smt1-gene
US8293718B2 (en) 2009-12-18 2012-10-23 Novartis Ag Organic compositions to treat HSF1-related diseases
CA2784711A1 (en) 2009-12-24 2011-06-30 E.I. Du Pont De Nemours And Company Plant membrane bound o-acyl transferase (mboat) family protein sequences and their uses for altering fatty acid compositions
WO2011082318A2 (en) 2009-12-30 2011-07-07 Pioneer Hi-Bred International, Inc. Methods and compositions for the introduction and regulated expression of genes in plants
WO2011082310A2 (en) 2009-12-30 2011-07-07 Pioneer Hi-Bred International, Inc. Methods and compositions for targeted polynucleotide modification
MX2012007855A (es) 2010-01-06 2013-06-05 Du Pont Identificacion de ritmos diurnos en tejidos fotosinteticos del zea mays y uso en el mejoramiento de plantas de cultivo.
US20110191910A1 (en) 2010-02-02 2011-08-04 E. I. Du Pont De Nemours And Company Plants with altered root architecture, related constructs and methods involving genes encoding lectin protein kinase (lpk) polypeptides and homologs thereof
CN102770767A (zh) 2010-02-10 2012-11-07 诺瓦提斯公司 用于肌肉生长的方法和组合物
EP2539362A1 (en) 2010-02-23 2013-01-02 BASF Plant Science Company GmbH Nematode-resistant transgenic plants
US20120331585A1 (en) 2010-02-24 2012-12-27 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and a method for making the same
US9388423B2 (en) 2010-02-24 2016-07-12 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and a method for making the same
EP2361927A1 (en) 2010-02-26 2011-08-31 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
EP2361985A1 (en) 2010-02-26 2011-08-31 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
BR112012022045A8 (pt) 2010-03-03 2018-06-19 Du Pont ''planta transgênica,semente transgênica,método para produzir uma planta transgênica,método para produzir sementes transgênicas,produto e/ou subproduto,polinucleotídeo isolado e planta ou semente''.
BR112012022880A2 (pt) 2010-03-18 2015-09-15 Basf Plant Science Co Gmbh métodos para aumentar o rendimento e/ou traços relacionados ao rendimento em plantas em relação a plantas de controle, para a produção de uma planta transgênica e para a produção de um produto, planta, construção, uso de uma construção, planta transgênica, partes colhíveis de uma planta, produtos derivados de uma planta e uso de um ácido nucleíco
US20130036516A1 (en) 2010-03-18 2013-02-07 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and method for making the same
CA2793394A1 (en) 2010-03-19 2011-09-22 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and a method for making the same
AR083141A1 (es) 2010-03-19 2013-02-06 Basf Plant Science Co Gmbh Plantas que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas
EP2371845A1 (en) 2010-03-22 2011-10-05 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
AU2011235276B2 (en) 2010-03-29 2015-09-03 Alnylam Pharmaceuticals, Inc. SiRNA therapy for transthyretin (TTR) related ocular amyloidosis
AU2011237630B2 (en) 2010-04-06 2016-01-21 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of CD274/PD-L1 gene
US20110277182A1 (en) 2010-05-06 2011-11-10 E.I. Dupont De Nemours And Company Maize acc synthase 3 gene and protein and uses thereof
CN103119152B (zh) 2010-05-11 2015-05-20 陶氏益农公司 Spnk菌株
CN107974457A (zh) 2010-05-28 2018-05-01 纽海姆有限公司 果实大小增大的植物
EP2576579B1 (en) 2010-06-02 2018-08-08 Alnylam Pharmaceuticals, Inc. Compositions and methods directed to treating liver fibrosis
CN105063063A (zh) 2010-06-24 2015-11-18 巴斯夫植物科学有限公司 具有增强的产量相关性状的植物和用于制备该植物的方法
KR101429468B1 (ko) 2010-06-25 2014-08-27 바스프 플랜트 사이언스 컴퍼니 게엠베하 향상된 수확량 관련 형질을 갖는 식물 및 이의 제조 방법
CA2803609A1 (en) 2010-07-01 2012-01-05 E. I. Du Pont De Nemours And Company Plant seeds with altered storage compound levels, related constructs and methods involving genes encoding pae and pae-like polypeptides
WO2012004013A2 (en) 2010-07-08 2012-01-12 Bayer Bioscience N.V. Glucosinolate transporter protein and uses thereof
US9512188B2 (en) 2010-07-12 2016-12-06 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Isolated polynucleotides and methods and plants using same for regulating plant acidity
EP2592945B1 (en) 2010-07-14 2018-01-17 E. I. du Pont de Nemours and Company Blended soy protein products with a combined pufa content having altered characteristics
BR112013000992A2 (pt) 2010-07-16 2016-05-24 Basf Plant Science Co Gmbh métodos para intensificar traços relacionados ao rendimento em plantas, construtos, usos de um construto, plantas, parte de plantas, células de plantas transformadas, métodos para a produção de uma planta transgênica, plantas transgênicas, partes colhíveis e produtos derivados de uma planta, usos de um ácido nucleico, moléculas de ácido nucleico isolado, polipeptídeos isolados e uso de ácidos nucleicos de rna helicase dead-box
EP2835427A3 (en) 2010-08-24 2015-05-20 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
US9260471B2 (en) 2010-10-29 2016-02-16 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)
US9585413B2 (en) 2010-11-04 2017-03-07 Arista Cereal Technology Pty Limited Food ingredients produced from high amylose wheat
US20130224116A1 (en) 2010-11-05 2013-08-29 TransBio Ltd. Markers of Endothelial Progenitor Cells and Uses Thereof
CN110123830A (zh) 2010-11-09 2019-08-16 阿尔尼拉姆医药品有限公司 用于抑制Eg5和VEGF基因的表达的脂质配制的组合物和方法
CN103298943A (zh) 2010-11-10 2013-09-11 巴斯夫植物科学有限公司 产量相关性状增强的植物及其制备方法
AU2011347674B2 (en) 2010-12-24 2015-01-15 BASF Agricultural Solutions Seed US LLC Brassica plant comprising a mutant ALCATRAZ allele
BR112013018545A2 (pt) 2011-01-20 2019-02-05 Basf Plant Science Co Gmbh plantas com características melhoras relacionadas á produção e um método para produção das mesma
BR112013018531A2 (pt) 2011-01-24 2016-10-18 Bayer Cropscience Nv uso do promotor rd29 ou fragmentos do mesmo para expressão induzível por estresse de transgenes em algodão
EA201391243A1 (ru) 2011-02-28 2014-07-30 Басф Плант Сайенс Компани Гмбх Растения, обладающие повышенными связанными с урожайностью свойствами, и способ их получения
WO2012117330A1 (en) 2011-02-28 2012-09-07 Basf Plant Science Company Gmbh Plants having enhanced yield-related traits and producing methods thereof
CN103582702A (zh) 2011-03-01 2014-02-12 巴斯夫植物科学有限公司 具有增强的产量相关性状的植物和用于制备该植物的方法
GB201103569D0 (en) 2011-03-02 2011-04-13 Plant Bioscience Ltd Mutants
CN103842511A (zh) 2011-03-23 2014-06-04 先锋国际良种公司 产生复合转基因性状基因座的方法
WO2012136788A1 (en) 2011-04-07 2012-10-11 Bayer Cropscience Nv Seed - specific promoter in cotton
GB201106845D0 (en) 2011-04-26 2011-06-01 Vib Vzw Methods and means to produce abiotic stress tolerant plants
US9677084B2 (en) 2011-04-29 2017-06-13 Pioneer Hi-Bred International, Inc. Down-regulation of a homeodomain-leucine zipper I-class homeobox gene for improved plant performance
DK2520653T3 (en) 2011-05-03 2017-07-03 Dow Agrosciences Llc INTEGRATION OF GENES IN THE CHROMOSOME OF SACCHAROPOLYSPORA SPINOSA
WO2012174139A2 (en) 2011-06-14 2012-12-20 Synthon Biopharmaceuticals B.V. Compositions and methods for making and b ioc ont aining auxotrophic transgenic plants
EP2723756B1 (en) 2011-06-21 2020-03-11 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibition of expression of apolipoprotein c-iii (apoc3) genes
EP2723351B1 (en) 2011-06-21 2018-02-14 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibition of expression of protein c (proc) genes
US9574208B2 (en) 2011-06-21 2017-02-21 Ei Du Pont De Nemours And Company Methods and compositions for producing male sterile plants
AU2012272908A1 (en) 2011-06-21 2013-12-19 Alnylam Pharmaceuticals, Inc. Assays and methods for determining activity of a therapeutic agent in a subject
EP2723861A4 (en) 2011-06-21 2014-12-10 Alnylam Pharmaceuticals Inc COMPOSITIONS AND METHODS FOR INHIBITING HEPCIDINE ANTIMICROBIAL PEPTIDE (HAMP) OR THE ASSOCIATED GENE EXPRESSION
US20140235693A1 (en) 2011-06-23 2014-08-21 Alnylam Pharmaceuticals, Inc. Serpina1 sirnas: compositions of matter and methods of treatment
US9181532B2 (en) 2011-07-29 2015-11-10 Icon Genetics Gmbh Production of galactosylated N-glycans in plants
EP2742059A1 (en) 2011-08-12 2014-06-18 Bayer CropScience NV Guard cell-specific expression of transgenes in cotton
CA2845581A1 (en) 2011-09-13 2013-03-21 E. I. Du Pont De Nemours And Company Soybean atps promoter and its use in constitutive expression of transgenic genes in plants
WO2013040259A1 (en) 2011-09-13 2013-03-21 E. I. Du Pont De Nemours And Company Soybean bbi3 promoter and its use in embryo-specific expression of transgenic genes in plants
US10196664B2 (en) 2011-10-04 2019-02-05 Icon Genetics Gmbh Nicotiana benthamiana plants deficient in fucosyltransferase activity
US20140251317A1 (en) 2011-10-12 2014-09-11 Bayer Cropscience Ag Plants with decreased activity of a starch dephosphorylating enzyme
WO2013053730A1 (en) 2011-10-12 2013-04-18 Bayer Cropscience Ag Plants with decreased activity of a starch dephosphorylating enzyme
US20150159166A1 (en) 2011-10-31 2015-06-11 Pioneer Hi Bred International Inc Plant drought tolerance and nitrogen use efficiency by reducing plant sensitivity to ethylene
EP2773183A4 (en) 2011-11-04 2015-04-15 Arista Cereal Technologies Pty Ltd WHEAT WITH HIGH AMYLOSE CONTENT - II
UA116097C2 (uk) 2011-12-11 2018-02-12 Зе Стейт Оф Ізраел, Міністрі Оф Агрікалче Енд Руерал Девелопмент, Агрікалчерал Рісьоч Організейшн, (А.Р.О.), Волкані Сентре Спосіб модуляції провідності устячка рослини
WO2013096818A1 (en) 2011-12-21 2013-06-27 The Curators Of The University Of Missouri Soybean variety s05-11268
WO2013096810A1 (en) 2011-12-21 2013-06-27 The Curators Of The University Of Missouri Soybean variety s05-11482
AU2012327162A1 (en) 2011-12-27 2013-07-11 Commonwealth Scientific And Industrial Research Organisation Production of dihydrosterculic acid and derivatives thereof
JP6461604B2 (ja) 2011-12-27 2019-01-30 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション 脂質製造のための工程
EP2798065B1 (en) 2011-12-27 2019-06-05 Commonwealth Scientific and Industrial Research Organisation Simultaneous gene silencing and supressing gene silencing in the same cell
US20150353949A1 (en) 2012-01-11 2015-12-10 The Australian National University Method for modulating plant root architecture
US10184131B2 (en) 2012-02-06 2019-01-22 A.B. Seeds Ltd. Isolated polynucleotides expressing or modulating microRNAs or targets of same, transgenic plants comprising same and uses thereof
WO2013138309A1 (en) 2012-03-13 2013-09-19 Pioneer Hi-Bred International, Inc. Genetic reduction of male fertility in plants
CN104703998B (zh) 2012-03-13 2020-08-21 先锋国际良种公司 植物中雄性育性的遗传减少
US10155959B2 (en) 2012-04-20 2018-12-18 Futuragene Israel Ltd. Bronze bug control agents
BR112014026363A2 (pt) 2012-04-23 2017-06-27 Futuragene Israel Ltd molécula de ácido ribonucleico, dsrna, vetor, célula hospedeira, tecido vegetal, ácido nucleico isolado, método de produção de planta resistente a pragas e método de inibição de infestação de pragas
KR102208924B1 (ko) 2012-04-25 2021-01-29 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 고 올레산 오일
US8835720B2 (en) 2012-04-26 2014-09-16 Monsanto Technology Llc Plants and seeds of spring canola variety SCV967592
US8859857B2 (en) 2012-04-26 2014-10-14 Monsanto Technology Llc Plants and seeds of spring canola variety SCV259778
US8878009B2 (en) 2012-04-26 2014-11-04 Monsanto Technology, LLP Plants and seeds of spring canola variety SCV318181
IN2014DN09920A (el) 2012-05-18 2015-08-14 Pioneer Hi Bred Int
EP2677035A1 (en) 2012-06-22 2013-12-25 BASF Plant Science Company GmbH Plants having enhanced yield-related traits and a method for making the same
CA2878383A1 (en) 2012-07-03 2014-01-09 E. I. Du Pont De Nemours And Company Environmentally sustainable frying oils
WO2014006159A1 (en) 2012-07-06 2014-01-09 Bayer Cropscience Nv Soybean rod1 gene sequences and uses thereof
AU2013285456B2 (en) 2012-07-06 2018-08-02 BASF Agricultural Solutions Seed US LLC Brassica ROD1 gene sequences and uses thereof
EA201590164A1 (ru) 2012-07-06 2015-05-29 Байер Кропсайенс Нв Растения brassica с модифицированным составом масла семян
BR112015002689A2 (pt) 2012-08-10 2017-08-01 Du Pont polinucleotídeo isolado, construção de dna recombinante, vetor, célula, vegetal transgênico, semente transgênica, método de expressão de uma sequência de codificação, métodos para alterar de maneira transgênica um aspecto comercializável do vegetal, para alterar a expressão de pelo menos um fragmento heterólogo de ácido nucleico e para expressar uma proteína fluorescente e vegetal estavelmente transformado.
US9719100B2 (en) 2012-08-10 2017-08-01 E I Du Pont De Nemours And Company Soybean ADF1 promoter and its use in constitutive expression of transgenic genes in plants
WO2014027021A1 (en) 2012-08-16 2014-02-20 Vib Vzw Means and methods for altering the lignin pathway in plants
CA2884296A1 (en) * 2012-09-07 2014-03-13 The Rockefeller University Transcriptional gene silencing of endogenes in plants
UY35064A (es) 2012-10-03 2014-04-30 Futuragene Israel Ltd Agentes para el control de la avispa de las agallas
AU2014211570A1 (en) 2013-01-29 2015-07-23 The University Court Of The University Of Glasgow Methods and means for increasing stress tolerance and biomass in plants
US20160002648A1 (en) 2013-03-11 2016-01-07 Mei Guo Genes for improving nutrient uptake and abiotic stress tolerance in plants
US9803214B2 (en) 2013-03-12 2017-10-31 Pioneer Hi-Bred International, Inc. Breeding pair of wheat plants comprising an MS45 promoter inverted repeat that confers male sterility and a construct that restores fertility
US20160017360A1 (en) 2013-03-13 2016-01-21 Pioneer Hi-Bred International, Inc. Functional expression of bacterial major facilitator superfamily mfs gene in maize to improve agronomic traits and grain yield
WO2014164074A1 (en) 2013-03-13 2014-10-09 Pioneer Hi-Bred International, Inc. Enhanced nitrate uptake and nitrate translocation by over-expressing maize functional low-affinity nitrate transporters in transgenic maize
EP2968424B1 (en) 2013-03-13 2020-01-22 Geneweave Biosciences Inc. Non-replicative transduction particles and transduction particle-based reporter systems
WO2014159477A1 (en) 2013-03-14 2014-10-02 E. I. Du Pont De Nemours And Company Soybean hrp1 promoter and its use in tissue-specific expression of transgenic genes in plants
BR112015023304A2 (pt) 2013-03-14 2017-07-18 Pioneer Hi Bred Int método para melhorar a tolerância ao estresse abiótico de uma planta, planta e semente
EP2971000A4 (en) 2013-03-15 2016-11-23 Pioneer Hi Bred Int PHI-4 POLYPEPTIDES AND METHOD FOR THEIR USE
US20160017350A1 (en) 2013-03-15 2016-01-21 Pioneer Hi-Bred International, Inc. Compositions and methods of use of acc oxidase polynucleotides and polypeptides
WO2014150721A1 (en) 2013-03-15 2014-09-25 E. I. Du Pont De Nemours And Company Soybean agb1 promoter and its use in tissue-specific expression of transgenic genes in plants
AU2014234265B2 (en) 2013-03-21 2020-01-30 Universiteit Gent Means and methods for the reduction of photorespiration in crops
EP2810952A1 (en) 2013-06-03 2014-12-10 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Novel pest control methods
CA2911185C (en) 2013-06-11 2023-09-05 Syngenta Participations Ag Methods for generating transgenic plants
CN105492591B (zh) 2013-06-13 2019-09-13 联邦科学技术研究组织 具有极低水平的大麦醇溶蛋白的大麦
EP3013329B1 (en) 2013-06-25 2020-08-05 The Walter and Eliza Hall Institute of Medical Research Smac mimetics for the treatment of persistent intracellular hbv infection
CA2917105C (en) 2013-07-01 2023-09-26 Bayer Cropscience Nv Methods and means for modulating flowering time in monocot plants
EA030896B1 (ru) 2013-08-16 2018-10-31 Пайонир Хай-Бред Интернэшнл, Инк. Инсектицидные белки и способы их применения
BR122021005579B1 (pt) 2013-09-13 2022-11-29 Pioneer Hi-Bred International, Inc Construto de dna, método de obtenção de planta transgênica, proteína de fusão, método para controlar uma população de praga de inseto, método para inibir o crescimento ou matar uma praga de inseto
US10093907B2 (en) 2013-09-24 2018-10-09 Basf Se Hetero-transglycosylase and uses thereof
US10428336B2 (en) 2013-10-16 2019-10-01 The Australian National University Method for modulating plant growth
US20160237445A1 (en) 2013-10-21 2016-08-18 E. I. Du Pont De Nemours And Company Soybean pip1 promoter and its use in constitutive expression of transgenic genes in plants
US10203327B2 (en) 2013-11-05 2019-02-12 Novartis Ag Organic compounds
DK3074038T3 (en) 2013-11-28 2019-03-11 Csl Ltd METHOD OF TREATING DIABETIC NEPHROPATHY
KR20160096194A (ko) 2013-12-18 2016-08-12 씨에스엘 리미티드 상처 치료 방법
EP2896698A1 (en) 2014-01-17 2015-07-22 BASF Plant Science Company GmbH Plants having one or more enhanced yield-related traits and a method for making the same
US20170166920A1 (en) 2014-01-30 2017-06-15 Two Blades Foundation Plants with enhanced resistance to phytophthora
CN117903266A (zh) 2014-02-07 2024-04-19 先锋国际良种公司 杀昆虫蛋白及其使用方法
WO2015171603A1 (en) 2014-05-06 2015-11-12 Two Blades Foundation Methods for producing plants with enhanced resistance to oomycete pathogens
BR112016030971B1 (pt) 2014-07-07 2022-09-27 Commonwealth Scientific And Industrial Research Organisation Processo para produzir um produto de óleo e processo para produzir um produto de óleo a partir do óleo da planta
EP3166964A1 (en) 2014-07-08 2017-05-17 Vib Vzw Means and methods to increase plant yield
BR112017000376A2 (pt) 2014-07-10 2017-11-07 Benson Hill Biosystems Inc composições e métodos para aumentar o desenvolvimento vegetal e seu rendimento
WO2016044090A1 (en) 2014-09-19 2016-03-24 E. I. Du Pont De Nemours And Company Soybean if5a promoter and its use in constitutive expression of transgenic genes in plants
ES2568693B1 (es) * 2014-10-02 2017-02-13 Universitat Politècnica De València Método para incrementar la fertilidad de las plantas
WO2016050512A1 (en) 2014-10-03 2016-04-07 Bayer Cropscience Nv Methods and means for increasing stress tolerance and biomass in plants
BR112017007932A2 (pt) 2014-10-16 2018-01-23 Du Pont proteínas inseticidas e métodos para uso das mesmas
WO2016079527A1 (en) 2014-11-19 2016-05-26 Tetralogic Birinapant Uk Ltd Combination therapy
CN107208112A (zh) 2014-11-25 2017-09-26 弗罗里达大学研究基金会有限公司 用于预防或降低细菌和真菌病原体对作物植物的感染的方法和组合物
US20170369902A1 (en) 2014-12-16 2017-12-28 Pioneer Hi-Bred International, Inc. Restoration of male fertility in wheat
WO2016099916A1 (en) 2014-12-19 2016-06-23 E. I. Du Pont De Nemours And Company Polylactic acid compositions with accelerated degradation rate and increased heat stability
WO2016097773A1 (en) 2014-12-19 2016-06-23 Children's Cancer Institute Therapeutic iap antagonists for treating proliferative disorders
WO2016113333A1 (en) 2015-01-16 2016-07-21 Bayer Cropscience Nv Leaf-preferential promoters and uses thereof
WO2016128519A1 (en) 2015-02-12 2016-08-18 Bayer Cropscience Nv Shoot apex-preferential promoters and uses thereof
BR112017017260A2 (pt) 2015-03-27 2018-04-17 Du Pont construções de dna, vetor, célula, plantas, semente, método de expressão de rna e método de modificação de local alvo
CA2985198A1 (en) 2015-05-19 2016-11-24 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
US10750690B2 (en) 2015-05-29 2020-08-25 Arcadia Biosciences, Inc. Reduced gluten grains and compositions thereof
MX2018001523A (es) 2015-08-06 2018-03-15 Pioneer Hi Bred Int Proteinas insecticidas derivadas de plantas y metodos para su uso.
EP3332010A1 (en) 2015-08-07 2018-06-13 Bayer CropScience NV Root-preferential and stress inducible promoter and uses thereof
SG10202007937SA (en) 2015-09-02 2020-09-29 Alnylam Pharmaceuticals Inc PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
EP3344774A1 (en) 2015-09-04 2018-07-11 Keygene N.V. Diplospory gene
WO2017062790A1 (en) 2015-10-09 2017-04-13 Two Blades Foundation Cold shock protein receptors and methods of use
CN108135145A (zh) 2015-10-16 2018-06-08 拜尔作物科学公司 在种子生产中具有改变的性质的芸苔属植物
EP3365450A2 (en) 2015-10-23 2018-08-29 Donald Danforth Plant Science Center Genes encoding c4 transporter proteins for use in increasing crop plant yield
CA3001681A1 (en) 2015-10-30 2017-05-04 Ajith Anand Methods and compositions for rapid plant transformation
ES2843556T3 (es) 2015-11-06 2021-07-19 Pioneer Hi Bred Int Métodos y composiciones de transformación de plantas mejorada
SG11201804169QA (en) 2015-11-18 2018-06-28 Commw Scient Ind Res Org Rice grain with thickened aleurone
EP3375445A4 (en) 2015-11-30 2019-08-07 Xie, Yanhui USE OF AKT2 IN THE DIAGNOSIS AND TREATMENT OF A TUMOR
WO2017105987A1 (en) 2015-12-18 2017-06-22 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
MX2018011298A (es) 2016-03-18 2019-03-07 Pioneer Hi Bred Int Metodos y composiciones para producir gametos clonados, sin reducir, sin recombinar.
US20190127747A1 (en) 2016-04-11 2019-05-02 Bayer Cropscience Nv Seed-specific and endosperm-preferential promoters and uses thereof
US10975380B2 (en) 2016-04-11 2021-04-13 Basf Agricultural Solutions Seed, Us Llc Seed-specific and endosperm-preferental promoters and uses thereof
BR112018071095A2 (pt) 2016-04-13 2019-02-26 Bayer Cropscience Nv promotores preferenciais em semente e funículo e usos dos mesmos
BR112018071103A2 (pt) 2016-04-13 2019-02-26 Bayer Cropscience Nv promotores específicos de semente e preferenciais em embrião e usos dos mesmos
WO2017192560A1 (en) 2016-05-04 2017-11-09 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN109476715B (zh) 2016-05-26 2023-06-27 纽海姆有限公司 产无籽果实的植物
EP3954202A1 (en) 2016-07-01 2022-02-16 Pioneer Hi-Bred International, Inc. Insecticidal proteins from plants and methods for their use
US11021716B2 (en) 2016-11-01 2021-06-01 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
WO2018140214A1 (en) 2017-01-24 2018-08-02 Pioneer Hi-Bred International, Inc. Nematicidal protein from pseudomonas
WO2018172181A1 (en) 2017-03-23 2018-09-27 Bayer Cropscience Nv Anther-specific promoter and uses thereof
WO2018217474A1 (en) 2017-05-24 2018-11-29 Bayer Cropscience Lp Fungal rust-inducible promoter
WO2019047914A1 (zh) 2017-09-07 2019-03-14 北京泰德制药股份有限公司 靶向ckip-1的双链rna分子及其用途
BR112020004268A2 (pt) 2017-09-18 2020-09-29 Futuragene Israel Ltd. construto, célula hospedeira, tecido vegetal, método para produzir uma planta, planta transgênica, método para engenheirar uma planta, planta, e, célula vegetal
WO2019083808A1 (en) 2017-10-24 2019-05-02 Basf Se IMPROVING HERBICIDE TOLERANCE AGAINST HPPD INHIBITORS BY REGULATION OF PUTATIVE REDUCED 4-HYDROXYPHENYLPYRUVATE REDUCES IN SOYBEANS
US11279944B2 (en) 2017-10-24 2022-03-22 BASF Agricultural Solutions Seed US LLC Of herbicide tolerance to 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors by down-regulation of HPPD expression in soybean
CN110484535B (zh) * 2018-05-14 2023-12-15 中国科学院分子植物科学卓越创新中心 对蚜虫高效致死的RNAi靶标基因及其应用
US11291176B2 (en) 2018-06-15 2022-04-05 Nunhems B.V. Seedless watermelon plants comprising modifications in an ABC transporter gene
MX2021000087A (es) 2018-06-27 2021-05-31 Basf Se Rubisco activasa termoestable y usos de esta.
US20210277409A1 (en) 2018-06-28 2021-09-09 Pioneer Hi-Bred International, Inc. Methods for selecting transformed plants
JP2022512706A (ja) 2018-10-16 2022-02-07 エフ.ホフマン-ラ ロシュ アーゲー 眼科におけるAkt阻害剤の使用
BR112021008329A2 (pt) 2018-10-31 2021-08-03 Pioneer Hi-Bred International, Inc. composições e métodos para transformação de plantas mediada por ochrobactrum
US20220091137A1 (en) 2019-01-17 2022-03-24 Hoffmann-La Roche Inc. E3 ubiquitin ligase (ube3a) protein targets
EP3744849A1 (en) 2019-05-31 2020-12-02 Consejo Superior de Investigaciones Cientificas (CSIC) Method for modulating the gene silencing degree induced by trans-acting small interfering rnas
WO2021004838A2 (en) 2019-07-05 2021-01-14 BASF Agricultural Solutions Seed US LLC Rubisco activase with reduced adp inhibition and uses thereof
WO2021019536A1 (en) 2019-07-30 2021-02-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Methods of controlling cannabinoid synthesis in plants or cells and plants and cells produced thereby
US20220290156A1 (en) 2019-08-27 2022-09-15 Sanofi Compositions and methods for inhibiting pcsk9
AU2019474716A1 (en) 2019-11-19 2022-07-07 Protalix Ltd. Removal of constructs from transformed cells
EP3825408A1 (en) 2019-11-19 2021-05-26 FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. Methods of multi-species insect pest control
US20230235352A1 (en) 2020-07-14 2023-07-27 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
EP4284513A1 (en) 2021-01-26 2023-12-06 Universite Brest Bretagne Occidentale Novel stim1 splicing variants and uses thereof
AU2022324708A1 (en) 2021-08-06 2024-02-15 Kws Vegetables B.V. Durable downy mildew resistance in spinach
WO2023020980A1 (en) 2021-08-16 2023-02-23 F. Hoffmann-La Roche Ag E3 ubiquitin ligase (ube3a) protein targets
WO2023052562A1 (en) 2021-10-01 2023-04-06 Basf Se Wheat plants with an increased yield
CA3232731A1 (en) 2021-10-01 2023-04-06 Marie-Therese Scheirlinck Plants with improved properties

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407956A (en) 1981-03-13 1983-10-04 The Regents Of The University Of California Cloned cauliflower mosaic virus DNA as a plant vehicle
CA1192510A (en) 1981-05-27 1985-08-27 Lawrence E. Pelcher Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
NL8200523A (nl) 1982-02-11 1983-09-01 Univ Leiden Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna.
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
EP0116718B2 (en) 1983-01-13 1996-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process for the introduction of expressible genes into plant cell genomes and agrobacterium strains carrying hybrid Ti plasmid vectors useful for this process
ATE198350T1 (de) 1983-10-20 2001-01-15 Univ New York State Res Found Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns
WO1985001856A1 (en) 1983-11-03 1985-05-09 Johannes Martenis Jacob De Wet Method for the transfer of exogenous genes in plants using pollen as a vector
US4615807A (en) 1985-07-23 1986-10-07 United States Environmental Resources, Corp. Method for wastewater treatment
US6617496B1 (en) 1985-10-16 2003-09-09 Monsanto Company Effecting virus resistance in plants through the use of negative strand RNAs
EP0242236B2 (en) 1986-03-11 1996-08-21 Plant Genetic Systems N.V. Plant cells resistant to glutamine synthetase inhibitors, made by genetic engineering
NZ219472A (en) 1986-03-28 1990-08-28 Calgene Inc Regulation of phenotype in plant cells using dsdna constructs
IL84459A (en) 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
AU2811889A (en) 1987-10-20 1989-05-23 Plant Genetic Systems N.V. A process for the production of biologically active peptide via the expression of modified storage seed protein genes in transgenic plants
US5638637A (en) 1987-12-31 1997-06-17 Pioneer Hi-Bred International, Inc. Production of improved rapeseed exhibiting an enhanced oleic acid content
US5922602A (en) 1988-02-26 1999-07-13 Biosource Technologies, Inc. Cytoplasmic inhibition of gene expression
IL89495A (en) 1988-03-08 1995-08-31 Ciba Geigy Ag The chemically controlled AND segment, which is used to control the replication of the AND segment related to plants or plant tissues and their production
GB8810120D0 (en) 1988-04-28 1988-06-02 Plant Genetic Systems Nv Transgenic nuclear male sterile plants
US5597718A (en) 1988-10-04 1997-01-28 Agracetus Genetically engineering cotton plants for altered fiber
GB8901673D0 (en) 1989-01-26 1989-03-15 Ici Plc Gene switch
US5034323A (en) 1989-03-30 1991-07-23 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5231020A (en) * 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
DE69034268D1 (de) 1989-08-10 2011-03-03 Bayer Bioscience Nv Pflanzen mit modifizierten Blüten
GB8923716D0 (en) 1989-10-20 1989-12-06 Ici Plc Dna,constructs,cells and plants derived therefrom
US5168064A (en) 1990-04-20 1992-12-01 The Regents Of The University Of California Endo-1,4-β-glucanase gene and its use in plants
GB9009307D0 (en) 1990-04-25 1990-06-20 Ici Plc Dna,constructs,cells and plant derived therefrom
MX9100993A (es) 1990-09-10 1992-05-04 Us Agriculture Secuencia de adn aislado y enzima acido 1-aminociclopropan-1-carboxilico sintasa,recombinante
WO1993003161A1 (en) 1990-10-22 1993-02-18 Biosource Genetics Corporation Recombinant plant viral nucleic acids
JP2576962Y2 (ja) 1990-11-09 1998-07-23 アイシン精機株式会社 粘性流体継手装置
JP3234598B2 (ja) 1990-11-23 2001-12-04 プラント・ジエネテイツク・システムズ・エヌ・ベー 単子葉植物の形質転換方法
SE9004095L (sv) 1990-12-21 1992-06-01 Amylogene Hb Genetisk foeraendring av potatis foer bildning av staerkelse av amylostyp
SE467358B (sv) 1990-12-21 1992-07-06 Amylogene Hb Genteknisk foeraendring av potatis foer bildning av staerkelse av amylopektintyp
CA2100251A1 (en) 1991-01-25 1992-07-26 Robert L. Lechner Regulation of nucleic acid translation
DE69233636D1 (de) 1991-02-08 2006-08-17 Bayer Bioscience Nv Staubblatt spezifische promotoren aus reis
GB9106713D0 (en) 1991-03-28 1991-05-15 Ici Plc Dna,dna constructs,cells and plants derived therefrom
CZ214593A3 (en) 1991-04-16 1994-07-13 Mogen Int Plants exhibiting male sterility, process of obtaining thereof and recombinant dna for application of such process
GB9109063D0 (en) 1991-04-26 1991-06-12 Ici Plc Modification of lignin synthesis in plants
CA2110169A1 (en) 1991-05-30 1992-12-10 Walter Van Der Eycken Nematode-responsive plant promoters
GB9112645D0 (en) 1991-06-12 1991-07-31 Cambridge Advanced Tech Modification of starch production
AU2273392A (en) 1991-07-11 1993-02-11 International Flower Developments Pty Ltd Genetic sequences encoding flavonoid pathway enzymes and uses therefor
WO1994001560A1 (en) 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
GB9119279D0 (en) 1991-09-10 1991-10-23 Ici Plc Modification of lignin synthesis in plants
GB9121074D0 (en) 1991-10-03 1991-11-13 Ici Plc Dna,dna constructs,cells and plants derived therefrom
RU2143000C1 (ru) 1991-11-20 1999-12-20 Моген Интернэшнл Н.В. Способ получения растения с пониженной восприимчивостью к растительным паразитическим нематодам (варианты), рекомбинантная днк (варианты), трансформирующий растение вектор, штамм agrobacterium и способ снижения ущерба урожаю
GB9210273D0 (en) 1992-05-13 1992-07-01 Ici Plc Dna
NZ255028A (en) 1992-07-02 1997-03-24 Hybridon Inc Antisense oligonucleotides resistant to nucleolytic degradation
EP0606454A1 (en) 1992-07-30 1994-07-20 Keygene N.V. Dna constructs, cells and plants derived therefrom
EP0665891A1 (en) 1992-10-15 1995-08-09 Mogen International N.V. Genetic moderation or restoration of plant phenotypes
ES2198408T3 (es) * 1992-11-17 2004-02-01 E.I. Du Pont De Nemours And Company Genes para delta 12 desaturasas de acidos grasos microsomales y enzimas afines de plantas.
ZA939767B (en) 1993-01-21 1994-09-14 Univ North Carolina State Nematode-resistant transgenic plants
CA2150133A1 (en) 1993-02-05 1994-08-18 Vincent Jean-Marie Armel Arondel Altered linolenic and linoleic acid content in plants
EP0620281A3 (en) 1993-03-31 1995-05-03 Mitsubishi Corp Oilseed plants producing valuable seeds with modified amino acid and fatty acid compositions.
WO1994029465A1 (en) 1993-06-08 1994-12-22 Nunhems Zaden B.V. Process for generating male sterile plants
DE69432796T2 (de) 1993-09-09 2004-04-29 Bayer Cropscience Gmbh Kombination von dna-sequenzen, die die bildung von modifizierter stärke in pflanzenzellen und pflanzen ermöglicht, verfahren zur herstellung dieser pflanzen
GB9318927D0 (en) 1993-09-13 1993-10-27 Zeneca Ltd Regulation of senescence
US5545366A (en) 1994-06-10 1996-08-13 Lust; Victor Molding arrangement to achieve short mold cycle time and method of molding
NZ291734A (en) 1994-08-30 1997-09-22 Commw Scient Ind Res Org Plant transcription regulators from circovirus; isolated nucleic acid molecules and transgenic plants
US5674683A (en) 1995-03-21 1997-10-07 Research Corporation Technologies, Inc. Stem-loop and circular oligonucleotides and method of using
CA2226088A1 (en) 1995-06-30 1997-01-23 Dna Plant Technology Corporation Delayed ripening tomato plants
CN1196091A (zh) * 1995-07-13 1998-10-14 里伯希姆药品公司 用于在植物中调节基因表达的组合物和方法
AU718082B2 (en) 1995-10-06 2000-04-06 Plant Genetic Systems N.V. Seed shattering
EP0771878A1 (en) 1995-10-31 1997-05-07 Plant Genetic Systems N.V. Plants with reduced glucosinolate content
US5773692A (en) 1995-12-12 1998-06-30 Her Majesty The Queen In Right Of Canada, As Represented By Agriculture And Agri-Food Canada Anti-sense RNA for CAB transcript to reduce chlorophyll content in plants
AU2089197A (en) * 1996-03-13 1997-10-01 National Research Council Of Canada Process of raising squalene levels in plants and dna sequences used therefor
US5850026A (en) 1996-07-03 1998-12-15 Cargill, Incorporated Canola oil having increased oleic acid and decreased linolenic acid content
DE19631919C2 (de) 1996-08-07 1998-07-16 Deutsches Krebsforsch Anti-Sinn-RNA mit Sekundärstruktur
GB9710475D0 (en) * 1997-05-21 1997-07-16 Zeneca Ltd Gene silencing
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
KR101085210B1 (ko) * 1998-03-20 2011-11-21 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 유전자 발현 조절방법

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