ATE198350T1 - Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns - Google Patents

Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns

Info

Publication number
ATE198350T1
ATE198350T1 AT91111983T AT91111983T ATE198350T1 AT E198350 T1 ATE198350 T1 AT E198350T1 AT 91111983 T AT91111983 T AT 91111983T AT 91111983 T AT91111983 T AT 91111983T AT E198350 T1 ATE198350 T1 AT E198350T1
Authority
AT
Austria
Prior art keywords
regulation
gene expression
gene
rns
disabled
Prior art date
Application number
AT91111983T
Other languages
English (en)
Inventor
Masayori Inouye
Takeshi Mizuno
Mei-Yin Chou
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27067361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE198350(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of ATE198350T1 publication Critical patent/ATE198350T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
AT91111983T 1983-10-20 1984-10-19 Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns ATE198350T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54352883A 1983-10-20 1983-10-20
US58528284A 1984-03-01 1984-03-01

Publications (1)

Publication Number Publication Date
ATE198350T1 true ATE198350T1 (de) 2001-01-15

Family

ID=27067361

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91111983T ATE198350T1 (de) 1983-10-20 1984-10-19 Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns

Country Status (5)

Country Link
EP (2) EP0467349B1 (de)
JP (2) JP2651442B2 (de)
AT (1) ATE198350T1 (de)
CA (1) CA1341091C (de)
DE (2) DE3486053T3 (de)

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US5107065A (en) * 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US5453566A (en) * 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US5276019A (en) * 1987-03-25 1994-01-04 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
CA2105595A1 (en) * 1992-09-23 1994-03-24 Ramaswamy Narayanan Antisense polynucleotides
FR2730637B1 (fr) 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
AU4672097A (en) * 1996-10-01 1998-04-24 Advanced Research And Technology Institute, Inc. Methods and compositions for inhibiting bacterial growth
EP0837142A1 (de) * 1996-10-15 1998-04-22 Smithkline Beecham Corporation Verfahren zum Nachweis essentieller Gene eines Erregers
US6139817A (en) * 1996-10-15 2000-10-31 Smithkline Beecham Corporation Method for determining gene essentiality in a pathogen
DE69737327T2 (de) * 1996-11-06 2007-11-08 Smithkline Beecham Corp. Verfahren zur identifizierung von essentiellen genen für das wachstum eines organismus
US7008776B1 (en) 1996-12-06 2006-03-07 Aventis Pharmaceuticals Inc. Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol
US6884430B1 (en) 1997-02-10 2005-04-26 Aventis Pharma S.A. Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
WO1998037213A1 (en) 1997-02-21 1998-08-27 Danisco A/S Antisense intron inhibition of starch branching enzyme expression
EP0921195A1 (de) * 1997-03-10 1999-06-09 Japan Tobacco Inc. Antisens-sequenzen
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
CA2294793A1 (fr) 1997-06-30 1999-01-14 Rhone-Poulenc Rorer S.A. Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede
CA2316808C (en) 1998-01-08 2007-04-10 Aventis Pharmaceuticals Products Inc. Transgenic rabbit that expresses a functional human lipoprotein (a)
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
US8598332B1 (en) 1998-04-08 2013-12-03 Bayer Cropscience N.V. Methods and means for obtaining modified phenotypes
US20040214330A1 (en) 1999-04-07 2004-10-28 Waterhouse Peter Michael Methods and means for obtaining modified phenotypes
DK1068311T3 (da) 1998-04-08 2011-08-08 Commw Scient Ind Res Org Fremgangsmåder og midler til opnåelse af modificerede fænotyper
US7148400B1 (en) 1999-04-20 2006-12-12 Bayer Bioscience N.V. Methods and means for delivering inhibitory RNA to plants and applications thereof
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
FR2799472B1 (fr) 1999-10-07 2004-07-16 Aventis Pharma Sa Preparation d'adenovirus recombinants et de banques adenovirales
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DK1301213T3 (en) 2000-07-21 2017-03-27 Revance Therapeutics Inc MULTI-COMPONENT SYSTEMS FOR BIOLOGICAL TRANSPORT
WO2002018607A2 (en) 2000-08-30 2002-03-07 North Carolina State University Transgenic plants containing molecular decoys that alter protein content therein
EP1368467B1 (de) 2000-11-07 2007-04-25 North Carolina State University Putrescin-n-methyltransferasepromotor
PT1331845E (pt) 2000-11-09 2012-04-12 Commw Scient Ind Res Org Cevada com reduzida atividade ssii e produtos contendo amido com um conteúdo de amilopectina reduzido
SG132542A1 (en) 2001-06-08 2007-06-28 Vector Tobacco Ltd Modifying nicotine and nitrosamine levels in tobacco
US7491506B2 (en) 2001-06-21 2009-02-17 The Regents Of The University Of California Inhibition of B-cell maturation and antibody production
FR2829136B1 (fr) 2001-08-29 2006-11-17 Aventis Pharma Sa Derives lipidiques d'aminoglycosides
EP1479985B1 (de) 2002-01-17 2017-06-14 Alfa Laval Corporate AB Getauchter Verdampfer umfassend einen Plattenwärmetauscher und ein zylindrisches Gehäuse in dem der Plattenwärmetauscher angeordnet ist
EP1481268A4 (de) 2002-02-07 2005-06-29 Covalent Partners Llc Nanofilm und membranzusammensetzungen
CN1646687A (zh) 2002-03-14 2005-07-27 联邦科学和工业研究组织 修饰的基因沉默rna及其用途
DE10212892A1 (de) 2002-03-20 2003-10-09 Basf Plant Science Gmbh Konstrukte und Verfahren zur Regulation der Genexpression
ATE517994T1 (de) 2003-06-30 2011-08-15 Commw Scient Ind Res Org Weizen mit veränderter verzweigungsenzymaktivität sowie daraus erhaltene stärke und stärkehaltige produkte
AU2004278748B2 (en) 2003-09-29 2008-09-11 The Regents Of The University Of California Methods for altering hematopoietic progenitor cell adhesion, differentiation, and migration
US7129042B2 (en) 2003-11-03 2006-10-31 Diagnostic Hybrids, Inc. Compositions and methods for detecting severe acute respiratory syndrome coronavirus
CA2594155C (en) 2004-12-30 2016-08-30 Commonwealth Scientific And Industrial Research Organisation A process for producing a food or beverage
FR2881143B1 (fr) 2005-01-27 2010-12-17 Librophyt Systeme de production de terpenoides dans les plantes
US8808698B2 (en) 2006-02-03 2014-08-19 The Regents Of The University Of California Methods for inhibition of lymphangiogenesis and tumor metastasis
EP2044204B1 (de) 2006-06-07 2014-04-30 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Pflanzliche expressionskonstrukte und verfahren zu deren nutzung
MY151438A (en) 2006-07-28 2014-05-30 Sanofi Aventis Compositions and method for treatment of tumors
EP2554674B1 (de) 2007-12-21 2014-11-05 Keygene N.V. Trichomenspezifische Promotoren
EP2100962A1 (de) 2008-03-12 2009-09-16 Biogemma Pflanzen mit verbesserter Widerstandsfähigkeit gegen Pathogene
EP2331071A1 (de) 2008-09-05 2011-06-15 Institut National De La Sante Et De La Recherche Medicale Neue multimodulare anordnung zur intrazellulären abgabe
EP2249160A1 (de) 2009-04-27 2010-11-10 Centre National de la Recherche Scientifique VDAC3-S als ein Zellmarker
BRPI1010843A2 (pt) 2009-06-08 2015-09-08 Nunhems Bv plantas tolerantes à seca
EA030460B1 (ru) 2010-05-28 2018-08-31 Нунхемс Б.Ф. Растения с увеличенным размером плода
EP2525224A1 (de) 2011-05-19 2012-11-21 Centre National de la Recherche Scientifique VDAC1-S als ein Zellmarker
FR2986803A1 (fr) 2012-02-13 2013-08-16 Apex Biosolutions Cytomegalovirus humain oncogenique
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016075314A1 (fr) 2014-11-13 2016-05-19 Institut National De La Recherche Agronomique Identification de facteurs de transcription de yarrowia lipolytica affectant la production de proteines
FR3028527A1 (fr) 2014-11-13 2016-05-20 Pivert Identification de facteurs de transcription de yarrowia lipolytica
CA2996806A1 (en) 2015-09-04 2017-03-09 Keygene N.V. Diplospory gene
FR3081169B1 (fr) 2018-05-15 2020-06-19 Messenger Biopharma Substitution de la coiffe des arn messagers par deux sequences d'arn introduites a leur extremite 5'

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
JPS581451Y2 (ja) * 1979-11-13 1983-01-11 浜野 純一 自動充填機における袋供給送り装置

Also Published As

Publication number Publication date
DE3486053D1 (de) 1993-03-11
EP0467349B1 (de) 2000-12-27
JP2694924B2 (ja) 1997-12-24
CA1341091C (en) 2000-09-05
EP0140308A2 (de) 1985-05-08
JP2651442B2 (ja) 1997-09-10
EP0140308A3 (en) 1987-05-27
EP0467349A1 (de) 1992-01-22
JPH09135686A (ja) 1997-05-27
DE3486479D1 (de) 2001-02-01
EP0140308B1 (de) 1993-01-27
EP0140308B2 (de) 2001-10-17
DE3486053T3 (de) 2004-01-08
DE3486053T2 (de) 1993-05-19
DE3486479T2 (de) 2001-09-20
JPS60232092A (ja) 1985-11-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time