ATE198350T1 - Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns - Google Patents

Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns

Info

Publication number
ATE198350T1
ATE198350T1 AT91111983T AT91111983T ATE198350T1 AT E198350 T1 ATE198350 T1 AT E198350T1 AT 91111983 T AT91111983 T AT 91111983T AT 91111983 T AT91111983 T AT 91111983T AT E198350 T1 ATE198350 T1 AT E198350T1
Authority
AT
Austria
Prior art keywords
regulation
gene expression
gene
rns
disabled
Prior art date
Application number
AT91111983T
Other languages
English (en)
Inventor
Masayori Inouye
Takeshi Mizuno
Mei-Yin Chou
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27067361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE198350(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of ATE198350T1 publication Critical patent/ATE198350T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Saccharide Compounds (AREA)
AT91111983T 1983-10-20 1984-10-19 Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns ATE198350T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54352883A 1983-10-20 1983-10-20
US58528284A 1984-03-01 1984-03-01

Publications (1)

Publication Number Publication Date
ATE198350T1 true ATE198350T1 (de) 2001-01-15

Family

ID=27067361

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91111983T ATE198350T1 (de) 1983-10-20 1984-10-19 Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns

Country Status (5)

Country Link
EP (2) EP0140308B2 (de)
JP (2) JP2651442B2 (de)
AT (1) ATE198350T1 (de)
CA (1) CA1341091C (de)
DE (2) DE3486479T2 (de)

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US5276019A (en) * 1987-03-25 1994-01-04 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
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FR2730637B1 (fr) 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
WO1998014567A2 (en) * 1996-10-01 1998-04-09 Advanced Research & Technology Institute Methods and compositions for inhibiting bacterial growth
US6139817A (en) * 1996-10-15 2000-10-31 Smithkline Beecham Corporation Method for determining gene essentiality in a pathogen
JPH10191990A (ja) * 1996-10-15 1998-07-28 Smithkline Beecham Corp 病原体に必須の遺伝子の測定法
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US7008776B1 (en) 1996-12-06 2006-03-07 Aventis Pharmaceuticals Inc. Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol
US6884430B1 (en) 1997-02-10 2005-04-26 Aventis Pharma S.A. Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
JP2001514491A (ja) 1997-02-21 2001-09-11 ダニスコ エイ／エス デンプン分枝酵素発現のアンチセンスイントロン阻害
WO1998040489A1 (en) * 1997-03-10 1998-09-17 Japan Tobacco Inc. Antisense base sequences
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
DE69826124T3 (de) 1997-06-30 2007-10-11 Institut Gustave Roussy Verabreichung der nukleinsäure in den quergestreiften muskel
JP2002500039A (ja) 1998-01-08 2002-01-08 アベンティス ファーマスーティカルズ プロダクツ インコーポレイテッド 機能あるヒトリポタンパク質（ａ）を発現するトランスジェニックウサギ
BRPI9908967B1 (pt) 1998-03-20 2017-05-30 Benitec Australia Ltd processos para reprimir, retardar ou de outro modo reduzir a expressão de um gene alvo em uma célula de planta
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US20040214330A1 (en) 1999-04-07 2004-10-28 Waterhouse Peter Michael Methods and means for obtaining modified phenotypes
US8598332B1 (en) 1998-04-08 2013-12-03 Bayer Cropscience N.V. Methods and means for obtaining modified phenotypes
AU760041B2 (en) 1998-04-08 2003-05-08 Commonwealth Scientific And Industrial Research Organisation Methods and means for obtaining modified phenotypes
US7148400B1 (en) 1999-04-20 2006-12-12 Bayer Bioscience N.V. Methods and means for delivering inhibitory RNA to plants and applications thereof
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
FR2799472B1 (fr) 1999-10-07 2004-07-16 Aventis Pharma Sa Preparation d'adenovirus recombinants et de banques adenovirales
GB0018307D0 (en) 2000-07-26 2000-09-13 Aventis Pharm Prod Inc Polypeptides
NZ521786A (en) 2000-03-31 2004-07-30 Aventis Pharma Inc NFIF-14b and NFIF-7a (nuclear factor kappa B inducing factor) polypeptides and nulciec acids and their use in compositions for inhibiting inflammation
JP5610659B2 (ja) 2000-07-21 2014-10-22 ルバンス セラピュティックス インク．Ｒｅｖａｎｃｅ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 多成分生物学的輸送システム
CN1330753C (zh) 2000-08-30 2007-08-08 北卡罗莱纳州立大学 含有可改变蛋白含量的分子诱导物的转基因植物
WO2002038588A2 (en) 2000-11-07 2002-05-16 North Carolina State University Putrescine-n-methyltransferase promoter
CN1482856A (zh) 2000-11-09 2004-03-17 ����Ƽ���ҵ�о���֯ 降低了ssii活性的大麦和降低了支链淀粉含量的淀粉和淀粉制品
EP1406518A4 (de) 2001-06-08 2006-03-29 Vector Tobacco Ltd Modifikation von nicotin- und nitrosaminkonzentrationen in tabak
US7491506B2 (en) 2001-06-21 2009-02-17 The Regents Of The University Of California Inhibition of B-cell maturation and antibody production
FR2829136B1 (fr) 2001-08-29 2006-11-17 Aventis Pharma Sa Derives lipidiques d'aminoglycosides
AU2003205545A1 (en) 2002-01-17 2003-07-30 York Refrigeration Aps Submerged evaporator with integrated heat exchanger
US7432371B2 (en) 2002-02-07 2008-10-07 Covalent Partners, Llc Nanofilm and membrane compositions
CN1646687A (zh) 2002-03-14 2005-07-27 联邦科学和工业研究组织 修饰的基因沉默rna及其用途
DE10212892A1 (de) 2002-03-20 2003-10-09 Basf Plant Science Gmbh Konstrukte und Verfahren zur Regulation der Genexpression
WO2005001098A1 (en) 2003-06-30 2005-01-06 Commonwealth Scientific And Industrial Research Organisation Wheat with altered branching enzyme activity and starch and starch containing products derived thereform
EP1685236A4 (de) 2003-09-29 2008-01-23 Univ California Verfahren zur änderung der adhäsion, differenzierung und migration hämatopoetischer vorläuferzellen
US7129042B2 (en) 2003-11-03 2006-10-31 Diagnostic Hybrids, Inc. Compositions and methods for detecting severe acute respiratory syndrome coronavirus
WO2006069422A1 (en) 2004-12-30 2006-07-06 Commonwealth Scientific And Industrial Research Organisation Method and means for improving bowel health
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WO2007092471A2 (en) 2006-02-03 2007-08-16 The Regents Of The University Of California Methods for inhibition of lymphangiogenesis and tumor metastasis
EP2436769B1 (de) 2006-06-07 2015-04-01 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Pflanzenexpressionskonstrukte und Verfahren zu deren Verwendung
AU2007276793B2 (en) 2006-07-28 2014-01-16 Sanofi Composition and method for treatment of tumors
US8809626B2 (en) 2007-12-21 2014-08-19 Keygene N.V. Trichome specific promoters
EP2100962A1 (de) 2008-03-12 2009-09-16 Biogemma Pflanzen mit verbesserter Widerstandsfähigkeit gegen Pathogene
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EP2249160A1 (de) 2009-04-27 2010-11-10 Centre National de la Recherche Scientifique VDAC3-S als ein Zellmarker
ES2879599T3 (es) 2009-06-08 2021-11-22 Nunhems Bv Plantas tolerantes a la sequía
MX344585B (es) 2010-05-28 2016-12-20 Nunhems Bv Platas con un tamaño de fruto incrementado.
EP2525224A1 (de) 2011-05-19 2012-11-21 Centre National de la Recherche Scientifique VDAC1-S als ein Zellmarker
FR2986803A1 (fr) 2012-02-13 2013-08-16 Apex Biosolutions Cytomegalovirus humain oncogenique
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
FR3028527A1 (fr) 2014-11-13 2016-05-20 Pivert Identification de facteurs de transcription de yarrowia lipolytica
WO2016075314A1 (fr) 2014-11-13 2016-05-19 Institut National De La Recherche Agronomique Identification de facteurs de transcription de yarrowia lipolytica affectant la production de proteines
CN108291234B (zh) 2015-09-04 2026-04-21 主基因有限公司 倍数孢子体形成基因
FR3081169B1 (fr) 2018-05-15 2020-06-19 Messenger Biopharma Substitution de la coiffe des arn messagers par deux sequences d'arn introduites a leur extremite 5'

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
JPS581451Y2 (ja) * 1979-11-13 1983-01-11 浜野 純一 自動充填機における袋供給送り装置

Also Published As

Publication number Publication date
CA1341091C (en) 2000-09-05
DE3486053D1 (de) 1993-03-11
DE3486053T2 (de) 1993-05-19
DE3486479T2 (de) 2001-09-20
JP2651442B2 (ja) 1997-09-10
JPH09135686A (ja) 1997-05-27
DE3486479D1 (de) 2001-02-01
JPS60232092A (ja) 1985-11-18
EP0140308B1 (de) 1993-01-27
EP0140308B2 (de) 2001-10-17
EP0467349B1 (de) 2000-12-27
EP0140308A2 (de) 1985-05-08
DE3486053T3 (de) 2004-01-08
EP0140308A3 (en) 1987-05-27
JP2694924B2 (ja) 1997-12-24
EP0467349A1 (de) 1992-01-22

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Legal Events

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UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time