ATE286126T1 - Glialmitogene faktoren, ihre herstellung und verwendung - Google Patents

Glialmitogene faktoren, ihre herstellung und verwendung

Info

Publication number
ATE286126T1
ATE286126T1 AT93918139T AT93918139T ATE286126T1 AT E286126 T1 ATE286126 T1 AT E286126T1 AT 93918139 T AT93918139 T AT 93918139T AT 93918139 T AT93918139 T AT 93918139T AT E286126 T1 ATE286126 T1 AT E286126T1
Authority
AT
Austria
Prior art keywords
glialmitogenic
factors
production
molecules
encode
Prior art date
Application number
AT93918139T
Other languages
English (en)
Inventor
Andrew Goodearl
Paul Stroobant
Luisa Minghetti
Michael Waterfield
Mark Marchioni
Maio Su Chen
Ian Hiles
Original Assignee
Ludwig Inst Cancer Res
Cambridge Neuroscience Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res, Cambridge Neuroscience Res filed Critical Ludwig Inst Cancer Res
Application granted granted Critical
Publication of ATE286126T1 publication Critical patent/ATE286126T1/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/4756Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT93918139T 1992-06-30 1993-06-29 Glialmitogene faktoren, ihre herstellung und verwendung ATE286126T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90713892A 1992-06-30 1992-06-30
US94038992A 1992-09-03 1992-09-03
US96517392A 1992-10-23 1992-10-23
US08/036,555 US5530109A (en) 1991-04-10 1993-03-24 DNA encoding glial mitogenic factors
PCT/US1993/006228 WO1994000140A1 (en) 1992-06-30 1993-06-29 Glial mitogenic factors, their preparation and use

Publications (1)

Publication Number Publication Date
ATE286126T1 true ATE286126T1 (de) 2005-01-15

Family

ID=27488375

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93918139T ATE286126T1 (de) 1992-06-30 1993-06-29 Glialmitogene faktoren, ihre herstellung und verwendung

Country Status (11)

Country Link
US (8) US5530109A (de)
EP (1) EP0653940B1 (de)
JP (1) JP4127567B2 (de)
KR (2) KR100344006B1 (de)
AT (1) ATE286126T1 (de)
AU (2) AU688270B2 (de)
CA (1) CA2139136A1 (de)
DE (1) DE69333731T2 (de)
ES (1) ES2236686T3 (de)
PT (1) PT101297B (de)
WO (1) WO1994000140A1 (de)

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US7319019B1 (en) * 1991-04-10 2008-01-15 Acorda Therapeutics, Inc. Glial mitogenic factors lacking an N-terminal signal sequence
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US20050106666A1 (en) * 1991-04-10 2005-05-19 Cambridge Neuroscience Glial mitogenic factors, their preparation and use
US6087323A (en) * 1992-04-03 2000-07-11 Cambridge Neuroscience, Inc. Use of neuregulins as modulators of cellular communication
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Also Published As

Publication number Publication date
PT101297A (pt) 1994-06-30
US5530109A (en) 1996-06-25
EP0653940A1 (de) 1995-05-24
US5792849A (en) 1998-08-11
JPH08509357A (ja) 1996-10-08
ES2236686T3 (es) 2005-07-16
EP0653940A4 (de) 1997-02-26
US6232286B1 (en) 2001-05-15
EP0653940B1 (de) 2004-12-29
WO1994000140A1 (en) 1994-01-06
KR100344006B1 (ko) 2002-12-11
JP4127567B2 (ja) 2008-07-30
PT101297B (pt) 1999-10-29
DE69333731T2 (de) 2006-03-09
DE69333731D1 (de) 2005-02-03
CA2139136A1 (en) 1994-01-06
US5602096A (en) 1997-02-11
US5854220A (en) 1998-12-29
US5621081A (en) 1997-04-15
US5606032A (en) 1997-02-25
US6147190A (en) 2000-11-14
KR100307943B1 (ko) 2001-12-01
AU4833897A (en) 1998-04-23
AU688270B2 (en) 1998-03-12
AU4769493A (en) 1994-01-24

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