DE3864585D1 - Dns-molekule, codierend fuer non-a-non-b-hepatitis-antigene und ihre verwendung zur herstellung dieser antigene. - Google Patents

Dns-molekule, codierend fuer non-a-non-b-hepatitis-antigene und ihre verwendung zur herstellung dieser antigene.

Info

Publication number
DE3864585D1
DE3864585D1 DE8888400790T DE3864585T DE3864585D1 DE 3864585 D1 DE3864585 D1 DE 3864585D1 DE 8888400790 T DE8888400790 T DE 8888400790T DE 3864585 T DE3864585 T DE 3864585T DE 3864585 D1 DE3864585 D1 DE 3864585D1
Authority
DE
Germany
Prior art keywords
antigens
coding
production
dna molecules
hepatitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888400790T
Other languages
English (en)
Inventor
Kazuhiro Corpo Omoda Takahashi
Tatsurou Shibui
Michiru Kamizono
Rie Matsui
Yutaka Teranishi
Shigetada Nakanishi
Naomi Kitamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP62140586A external-priority patent/JP2590885B2/ja
Priority claimed from JP28399087A external-priority patent/JPH01124387A/ja
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Application granted granted Critical
Publication of DE3864585D1 publication Critical patent/DE3864585D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8888400790T 1987-03-31 1988-03-31 Dns-molekule, codierend fuer non-a-non-b-hepatitis-antigene und ihre verwendung zur herstellung dieser antigene. Expired - Fee Related DE3864585D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7831387 1987-03-31
JP62140586A JP2590885B2 (ja) 1987-03-31 1987-06-04 Ｄｎａ断片
JP28399087A JPH01124387A (ja) 1987-11-10 1987-11-10 非ａ非ｂ型肝炎特異抗原をコードするｄｎａを有する発現ベクター、形質転換体および該抗原の産生方法

Publications (1)

Publication Number Publication Date
DE3864585D1 true DE3864585D1 (de) 1991-10-10

Family

ID=27302677

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888400790T Expired - Fee Related DE3864585D1 (de) 1987-03-31 1988-03-31 Dns-molekule, codierend fuer non-a-non-b-hepatitis-antigene und ihre verwendung zur herstellung dieser antigene.

Country Status (5)

Country Link
US (1) US5032511A (de)
EP (1) EP0293274B1 (de)
KR (1) KR880011342A (de)
CN (1) CN1031717A (de)
DE (1) DE3864585D1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5218099A (en) * 1986-04-01 1993-06-08 The United States Of America As Represented By The Department Of Health And Human Services Post-transfusion, non-A, non-B hepatitis virus polynucleotides
US5714596A (en) * 1987-11-18 1998-02-03 Chiron Corporation NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
US5698390A (en) * 1987-11-18 1997-12-16 Chiron Corporation Hepatitis C immunoassays
US6861212B1 (en) 1987-11-18 2005-03-01 Chiron Corporation NANBV diagnostics and vaccines
US5712088A (en) * 1987-11-18 1998-01-27 Chiron Corporation Methods for detecting Hepatitis C virus using polynucleotides specific for same
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US5322769A (en) * 1988-03-11 1994-06-21 Abbott Laboratories Methods for using CKS fusion proteins
AU4046489A (en) * 1988-07-06 1990-02-05 Genelabs Incorporated Post-transfusion, non-a, non-b hepatitis virus and antigens
US5191064A (en) * 1988-09-30 1993-03-02 The Research Foundation For Microbial Diseases (Osaka University) Non-a, non-b hepatitis virus antigen peptide
HU225068B1 (en) * 1989-03-17 2006-05-29 Chiron Corp Process for producing diagnostics and vaccine of nanbh
US6027729A (en) * 1989-04-20 2000-02-22 Chiron Corporation NANBV Diagnostics and vaccines
JPH0330676A (ja) * 1989-06-28 1991-02-08 Sanwa Kagaku Kenkyusho Co Ltd 非ａ非ｂ型肝炎ウイルスのｄｎａ、そのクローン及びこれらの調製法
CA2065287C (en) * 1989-09-15 1999-12-21 Tatsuo Miyamura New hcv isolates
NZ236491A (en) * 1989-12-18 1993-10-26 Wellcome Found Post-transfusional non-a non-b hepatitis viral polypeptides, dna, antigenic polypeptides and antibodies to the polypeptides
US7166287B1 (en) 1989-12-18 2007-01-23 Glaxo Wellcome Inc. Viral agent
EP0435229A1 (de) * 1989-12-27 1991-07-03 Sanwa Kagaku Kenkyusho Co., Ltd. DNS-Gen von einem Non-A Non-B Hepatitis-Virus, seine Klonierung und Verwendung
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
US5747239A (en) * 1990-02-16 1998-05-05 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and preventions thereof as vaccines
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
DK0527815T3 (da) * 1990-04-06 2000-11-06 Genelabs Tech Inc Hepatitis C-virus-epitop
JP3050395B2 (ja) * 1990-06-12 2000-06-12 国立感染症研究所長 Ｃ型肝炎ウイルス抗原ポリペプチド、その産生方法および抗体の検出方法
US5747339A (en) 1990-06-25 1998-05-05 Research Foundation For Microbial Diseases Of Osaka Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide
ES2069298T3 (es) * 1990-06-30 1995-05-01 Akzo Nobel Nv Secuencias no-a no-b.
DE69133552C5 (de) * 1990-08-25 2008-01-10 F. Hoffmann-La Roche Ltd. Nicht-A, nicht-B Hepatitis Virus Antigen, und diagnostische Verfahren.
AU667462B2 (en) * 1990-11-30 1996-03-28 Monoclonetics International Incorporated Methods for the diagnosis of chronic lower back and cervical pain
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
JPH05130874A (ja) * 1991-11-07 1993-05-28 Sanwa Kagaku Kenkyusho Co Ltd ヒトＣ型肝炎ウイルスのｃＤＮＡ、そのクローン及びこれらの利用法
WO1994018217A1 (en) * 1993-02-03 1994-08-18 Abbott Laboratories Non-a, non-b, non-c, non-d, non-e hepatitis reagents and methods for their use
US5859230A (en) * 1992-07-30 1999-01-12 Genelabs Technologies, Inc. Non-A/non-B/non-C/non-D/non-E hepatitis agents and molecular cloning thereof
ATE322547T1 (de) * 1993-06-10 2006-04-15 Genetic Therapy Inc Adenovirale vektoren für die behandlung der hämophilie
US5824507A (en) * 1994-05-20 1998-10-20 Genelabs Technologies, Inc. Hepatitis G virus and molecular cloning thereof
US5874563A (en) * 1994-05-20 1999-02-23 Genelabs Technologies, Inc. Hepatitis G virus and molecular cloning thereof
US5613577A (en) * 1994-12-09 1997-03-25 Ford Motor Company Automotive disc brake with improved caliper assembly
EP2042612B1 (de) * 2004-01-23 2010-12-15 bioMerieux, Inc. Neuartiges Nukleotidgemisch für eine verbesserte Nukleinsäurenamplifikationsleistung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57198867A (en) * 1981-06-02 1982-12-06 Eisai Co Ltd Non-a, non-b hepatitis related antigen and diagnostic therefor
JPS58183629A (ja) * 1982-04-21 1983-10-26 Eisai Co Ltd 非ａ非ｂ型肝炎関連モノクロナ−ル抗体および診断薬
ZA8410091B (en) * 1984-03-02 1985-08-28 Warner Lambert Co Detection of non-a,non-b hepatitis
JPS61176856A (ja) * 1985-02-01 1986-08-08 Mitsubishi Chem Ind Ltd 非ａ非ｂ型肝炎抗原
JPS6391328A (ja) * 1986-10-07 1988-04-22 Mitsubishi Kasei Corp 非ａ非ｂ型肝炎抗原

Also Published As

Publication number Publication date
EP0293274B1 (de) 1991-09-04
CN1031717A (zh) 1989-03-15
KR880011342A (ko) 1988-10-27
EP0293274A1 (de) 1988-11-30
US5032511A (en) 1991-07-16

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee