DE69333731D1 - Glialmitogene faktoren, ihre herstellung und verwendung - Google Patents

Glialmitogene faktoren, ihre herstellung und verwendung

Info

Publication number
DE69333731D1
DE69333731D1 DE69333731T DE69333731T DE69333731D1 DE 69333731 D1 DE69333731 D1 DE 69333731D1 DE 69333731 T DE69333731 T DE 69333731T DE 69333731 T DE69333731 T DE 69333731T DE 69333731 D1 DE69333731 D1 DE 69333731D1
Authority
DE
Germany
Prior art keywords
glialmitogenic
factors
manufacture
molecules
encode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333731T
Other languages
English (en)
Other versions
DE69333731T2 (de
Inventor
Andrew Goodearl
Paul Stroobant
Luisa Minghetti
Michael Waterfield
Mark Marchioni
Su Chen
Ian Hiles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research New York
Acorda Therapeutics Inc
Original Assignee
Ludwig Institute for Cancer Research New York
Cambridge Neuroscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Institute for Cancer Research New York, Cambridge Neuroscience Inc filed Critical Ludwig Institute for Cancer Research New York
Application granted granted Critical
Publication of DE69333731D1 publication Critical patent/DE69333731D1/de
Publication of DE69333731T2 publication Critical patent/DE69333731T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE69333731T 1992-06-30 1993-06-29 Glialmitogene faktoren, ihre herstellung und verwendung Expired - Lifetime DE69333731T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US940389 1978-09-07
US907138 1986-09-12
US90713892A 1992-06-30 1992-06-30
US94038992A 1992-09-03 1992-09-03
US96517392A 1992-10-23 1992-10-23
US08/036,555 US5530109A (en) 1991-04-10 1993-03-24 DNA encoding glial mitogenic factors
US36555 1993-03-24
PCT/US1993/006228 WO1994000140A1 (en) 1992-06-30 1993-06-29 Glial mitogenic factors, their preparation and use
US965173 1997-11-06

Publications (2)

Publication Number Publication Date
DE69333731D1 true DE69333731D1 (de) 2005-02-03
DE69333731T2 DE69333731T2 (de) 2006-03-09

Family

ID=27488375

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333731T Expired - Lifetime DE69333731T2 (de) 1992-06-30 1993-06-29 Glialmitogene faktoren, ihre herstellung und verwendung

Country Status (11)

Country Link
US (8) US5530109A (de)
EP (1) EP0653940B1 (de)
JP (1) JP4127567B2 (de)
KR (2) KR100344006B1 (de)
AT (1) ATE286126T1 (de)
AU (2) AU688270B2 (de)
CA (1) CA2139136A1 (de)
DE (1) DE69333731T2 (de)
ES (1) ES2236686T3 (de)
PT (1) PT101297B (de)
WO (1) WO1994000140A1 (de)

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US20050106666A1 (en) * 1991-04-10 2005-05-19 Cambridge Neuroscience Glial mitogenic factors, their preparation and use
US5716930A (en) * 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
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US7115554B1 (en) * 1993-05-06 2006-10-03 Acorda Therapeutics, Inc. Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III
US7037888B1 (en) * 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
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Also Published As

Publication number Publication date
DE69333731T2 (de) 2006-03-09
JPH08509357A (ja) 1996-10-08
AU4769493A (en) 1994-01-24
US5792849A (en) 1998-08-11
US5621081A (en) 1997-04-15
KR100307943B1 (ko) 2001-12-01
EP0653940A1 (de) 1995-05-24
WO1994000140A1 (en) 1994-01-06
ES2236686T3 (es) 2005-07-16
US5606032A (en) 1997-02-25
US6147190A (en) 2000-11-14
US6232286B1 (en) 2001-05-15
AU4833897A (en) 1998-04-23
US5530109A (en) 1996-06-25
CA2139136A1 (en) 1994-01-06
PT101297A (pt) 1994-06-30
ATE286126T1 (de) 2005-01-15
EP0653940B1 (de) 2004-12-29
JP4127567B2 (ja) 2008-07-30
AU688270B2 (en) 1998-03-12
PT101297B (pt) 1999-10-29
US5602096A (en) 1997-02-11
KR100344006B1 (ko) 2002-12-11
EP0653940A4 (de) 1997-02-26
US5854220A (en) 1998-12-29

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