DE69504808T2 - Corticotropin freisetzende rezeptoren des faktor 2 - Google Patents

Corticotropin freisetzende rezeptoren des faktor 2

Info

Publication number
DE69504808T2
DE69504808T2 DE69504808T DE69504808T DE69504808T2 DE 69504808 T2 DE69504808 T2 DE 69504808T2 DE 69504808 T DE69504808 T DE 69504808T DE 69504808 T DE69504808 T DE 69504808T DE 69504808 T2 DE69504808 T2 DE 69504808T2
Authority
DE
Germany
Prior art keywords
receptors
factor
corticotropin releasing
sub
releasing receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69504808T
Other languages
English (en)
Other versions
DE69504808T3 (de
DE69504808D1 (de
Inventor
Derek Chalmers
Timothy W Lovenberg
Tilman Oltersdorf
Chen Wang Liaw
Dimitri E Grigoriadis
Souza Errol B De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurocrine Biosciences Inc
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27401275&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69504808(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/381,433 external-priority patent/US5786203A/en
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Application granted granted Critical
Publication of DE69504808D1 publication Critical patent/DE69504808D1/de
Publication of DE69504808T2 publication Critical patent/DE69504808T2/de
Publication of DE69504808T3 publication Critical patent/DE69504808T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2228—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
DE69504808T 1994-06-14 1995-06-14 Corticotropin freisetzende rezeptoren des faktor 2 Expired - Lifetime DE69504808T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25995994A 1994-06-14 1994-06-14
US08/381,433 US5786203A (en) 1994-06-14 1995-01-31 Isolated nucleic acid encoding corticotropin-releasing factor2 receptors
US48598495A 1995-06-07 1995-06-07
PCT/US1995/007757 WO1995034651A2 (en) 1994-06-14 1995-06-14 Corticotropin-releasing factor2 receptors

Publications (3)

Publication Number Publication Date
DE69504808D1 DE69504808D1 (de) 1998-10-22
DE69504808T2 true DE69504808T2 (de) 1999-05-12
DE69504808T3 DE69504808T3 (de) 2002-12-12

Family

ID=27401275

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69504808T Expired - Lifetime DE69504808T3 (de) 1994-06-14 1995-06-14 Corticotropin freisetzende rezeptoren des faktor 2

Country Status (10)

Country Link
US (2) US6723841B2 (de)
EP (1) EP0724637B2 (de)
JP (1) JPH10501420A (de)
AT (1) ATE171212T1 (de)
AU (1) AU703140B2 (de)
CA (1) CA2193072A1 (de)
DE (1) DE69504808T3 (de)
DK (1) DK0724637T4 (de)
ES (1) ES2123269T5 (de)
WO (1) WO1995034651A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232329A1 (en) * 1994-06-10 2003-12-18 Jeffrey R. De Wet Novel human crh receptor-related receptor
US6214797B1 (en) 1995-06-13 2001-04-10 The Salk Institute For Biological Studies Urocortin peptides, nucleic acid encoding same methods for using same
EP0845035A2 (de) * 1995-06-13 1998-06-03 The Salk Institute For Biological Studies Urocortin peptiden
US6576441B1 (en) 1995-12-06 2003-06-10 Sumitomo Pharmaceuticals Company, Limited Semaphorin Z and gene encoding the same
BR9707783A (pt) * 1996-02-28 1999-07-27 Novartis Ag Promotores provenientes de genes para protoporfirnogênio oxidase em vegetais
US5888811A (en) * 1996-05-23 1999-03-30 Dupont Pharmaceuticals Company Corticotropin-releasing hormone receptor
AU7935098A (en) * 1997-06-30 1999-01-19 Taisho Pharmaceutical Co., Ltd. Proteins capable of binding to corticotropin-releasing factor
JP2002541840A (ja) * 1999-04-15 2002-12-10 ケンブリッジ・ユニヴァーシティ・テクニカル・サーヴィシズ・リミテッド 電位ゲート性ナトリウムチャネル由来のβサブユニットタンパク質の新規ファミリー、それらをコードする核酸、およびその治療的または診断的使用
US7674463B1 (en) * 1999-07-15 2010-03-09 Research Development Foundation Method of inhibiting angiogenesis by administration of a corticotropin releasing factor receptor 2 agonist
RU2251838C2 (ru) * 1999-07-15 2005-05-20 Рисерч Дивелопмент Фаундейшн Способ получения неприродной трансгенной мыши с дефицитом гена рецептора 2 кортиколиберина и ее использование
WO2001014888A1 (en) * 1999-08-24 2001-03-01 The Regents Of The University Of California Method of identifying urotensin ii receptor antagonists
KR20040014926A (ko) * 2000-07-19 2004-02-18 브리스톨-마이어스 스퀴브 파마 컴파니 조합 요법에서의 ｃｒｆ２ 리간드
JP4830079B2 (ja) * 2000-11-29 2011-12-07 国立感染症研究所長 プロテアーゼ活性の測定方法
US6670140B2 (en) * 2001-03-06 2003-12-30 The Procter & Gamble Company Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
WO2005103690A2 (en) * 2004-04-24 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with corticotropin releasing hormone receptor 2 (crhr2)
CN102272600A (zh) * 2008-12-31 2011-12-07 雅培医护站股份有限公司 用于使用核苷酸缀合物的免疫测定的方法和设备
JOP20170153A1 (ar) 2016-07-15 2019-01-30 Lilly Co Eli نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232329A1 (en) 1994-06-10 2003-12-18 Jeffrey R. De Wet Novel human crh receptor-related receptor
US5786203A (en) 1994-06-14 1998-07-28 Neurocrine Biosciences, Inc. Isolated nucleic acid encoding corticotropin-releasing factor2 receptors

Also Published As

Publication number Publication date
WO1995034651A3 (en) 1996-03-14
EP0724637B2 (de) 2002-06-05
ATE171212T1 (de) 1998-10-15
AU2945595A (en) 1996-01-05
DK0724637T3 (da) 1999-06-14
US20040185533A1 (en) 2004-09-23
AU703140B2 (en) 1999-03-18
DE69504808T3 (de) 2002-12-12
EP0724637A1 (de) 1996-08-07
EP0724637B1 (de) 1998-09-16
JPH10501420A (ja) 1998-02-10
US6723841B2 (en) 2004-04-20
US7034118B2 (en) 2006-04-25
DE69504808D1 (de) 1998-10-22
ES2123269T5 (es) 2002-11-01
ES2123269T3 (es) 1999-01-01
DK0724637T4 (da) 2002-09-16
CA2193072A1 (en) 1995-12-21
WO1995034651A2 (en) 1995-12-21
US20020077468A1 (en) 2002-06-20

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings