SI3222724T1 - Nadaljnje nove oblike molekul interferenčne RNA - Google Patents
Nadaljnje nove oblike molekul interferenčne RNAInfo
- Publication number
- SI3222724T1 SI3222724T1 SI200332582T SI200332582T SI3222724T1 SI 3222724 T1 SI3222724 T1 SI 3222724T1 SI 200332582 T SI200332582 T SI 200332582T SI 200332582 T SI200332582 T SI 200332582T SI 3222724 T1 SI3222724 T1 SI 3222724T1
- Authority
- SI
- Slovenia
- Prior art keywords
- rna molecules
- interfering rna
- stretch
- further novel
- novel forms
- Prior art date
Links
Classifications
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
- C12Y207/11001—Non-specific serine/threonine protein kinase (2.7.11.1), i.e. casein kinase or checkpoint kinase
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- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
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- C12N2310/321—2'-O-R Modification
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- C12N2310/32—Chemical structure of the sugar
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- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/343—Spatial arrangement of the modifications having patterns, e.g. ==--==--==--
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- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/35—Nature of the modification
- C12N2310/352—Nature of the modification linked to the nucleic acid via a carbon atom
- C12N2310/3521—Methyl
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- C12N2310/35—Nature of the modification
- C12N2310/352—Nature of the modification linked to the nucleic acid via a carbon atom
- C12N2310/3525—MOE, methoxyethoxy
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- C12N2310/531—Stem-loop; Hairpin
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Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02017601A EP1389637B1 (en) | 2002-08-05 | 2002-08-05 | Blunt-ended interfering RNA molecules |
US40254102P | 2002-08-12 | 2002-08-12 | |
EP03008383 | 2003-04-10 | ||
EP17160954.8A EP3222724B1 (en) | 2002-08-05 | 2003-08-05 | Further novel forms of interfering rna molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3222724T1 true SI3222724T1 (sl) | 2019-03-29 |
Family
ID=31720998
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200332582T SI3222724T1 (sl) | 2002-08-05 | 2003-08-05 | Nadaljnje nove oblike molekul interferenčne RNA |
SI200332565T SI1857547T1 (sl) | 2002-08-05 | 2003-08-05 | Nadaljnje nove oblike molekul interferenčne rna |
SI200332526T SI2258847T1 (sl) | 2002-08-05 | 2003-08-05 | Nadaljnje nove oblike molekul interferenčne RNA |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200332565T SI1857547T1 (sl) | 2002-08-05 | 2003-08-05 | Nadaljnje nove oblike molekul interferenčne rna |
SI200332526T SI2258847T1 (sl) | 2002-08-05 | 2003-08-05 | Nadaljnje nove oblike molekul interferenčne RNA |
Country Status (19)
Country | Link |
---|---|
US (15) | US7452987B2 (sl) |
EP (6) | EP2258847B2 (sl) |
JP (4) | JP5490655B2 (sl) |
KR (1) | KR101201664B1 (sl) |
CN (1) | CN100543137C (sl) |
AT (1) | ATE350473T2 (sl) |
AU (2) | AU2003260370B2 (sl) |
BR (1) | BRPI0313202A8 (sl) |
CA (1) | CA2494930C (sl) |
CY (4) | CY1106422T1 (sl) |
DE (1) | DE60310944T3 (sl) |
DK (4) | DK1857547T3 (sl) |
ES (1) | ES2280826T5 (sl) |
IL (2) | IL166546A0 (sl) |
MX (1) | MXPA05001355A (sl) |
PT (1) | PT1527176E (sl) |
SI (3) | SI3222724T1 (sl) |
WO (1) | WO2004015107A2 (sl) |
ZA (1) | ZA200500459B (sl) |
Families Citing this family (259)
Publication number | Priority date | Publication date | Assignee | Title |
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