MXPA05001355A - Formas nuevas adicionales de moleculas de arn de interferencia. - Google Patents
Formas nuevas adicionales de moleculas de arn de interferencia.Info
- Publication number
- MXPA05001355A MXPA05001355A MXPA05001355A MXPA05001355A MXPA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A MX PA05001355 A MXPA05001355 A MX PA05001355A
- Authority
- MX
- Mexico
- Prior art keywords
- rna molecules
- interfering rna
- stretch
- further novel
- novel forms
- Prior art date
Links
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
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- C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
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Abstract
La presente invencion esta relacionada con un acido ribonucleico que comprende una estructura de hebra doble en donde la estructura de hebra doble comprende una hebra y una segunda hebra, en donde la primera hebra comprende una primera extension de nucleotidos contiguos y en donde la primera extension es por lo menos parcialmente complementaria a un acido nucleico objetivo, y la segunda hebra comprende una segunda extension de nucleotidos contiguos en donde la segunda extension es por lo menos parcialmente identica al acido nucleico objetivo, y en donde la estructura de hebra doble tiene el extremo embotado.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02017601A EP1389637B1 (en) | 2002-08-05 | 2002-08-05 | Blunt-ended interfering RNA molecules |
US40254102P | 2002-08-12 | 2002-08-12 | |
EP03008383 | 2003-04-10 | ||
PCT/EP2003/008666 WO2004015107A2 (en) | 2002-08-05 | 2003-08-05 | Further novel forms of interfering rna molecules |
Publications (1)
Publication Number | Publication Date |
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MXPA05001355A true MXPA05001355A (es) | 2005-09-30 |
Family
ID=31720998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05001355A MXPA05001355A (es) | 2002-08-05 | 2003-08-05 | Formas nuevas adicionales de moleculas de arn de interferencia. |
Country Status (19)
Country | Link |
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US (15) | US7452987B2 (es) |
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