CY1110292T1 - Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης - Google Patents

Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης

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Publication number
CY1110292T1
CY1110292T1 CY20101100217T CY101100217T CY1110292T1 CY 1110292 T1 CY1110292 T1 CY 1110292T1 CY 20101100217 T CY20101100217 T CY 20101100217T CY 101100217 T CY101100217 T CY 101100217T CY 1110292 T1 CY1110292 T1 CY 1110292T1
Authority
CY
Cyprus
Prior art keywords
treatment
methods
compounds
pyrimidinodymine
immune diseases
Prior art date
Application number
CY20101100217T
Other languages
Greek (el)
English (en)
Inventor
Rajinder Singh
Ankush Argade
Donald G Payan
Jeffrey Clough
Holger Keim
Catherine Sylvain
Hui Li
Somasekhar Bhamidipati
Original Assignee
Rigel Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31721742&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1110292(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rigel Pharmaceuticals, Inc. filed Critical Rigel Pharmaceuticals, Inc.
Publication of CY1110292T1 publication Critical patent/CY1110292T1/el

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Transplantation (AREA)
CY20101100217T 2002-07-29 2010-03-09 Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης CY1110292T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39967302P 2002-07-29 2002-07-29
US44394903P 2003-01-31 2003-01-31
US45233903P 2003-03-06 2003-03-06
EP03784871A EP1534286B1 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
US10/631,029 US7517886B2 (en) 2002-07-29 2003-07-29 Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds

Publications (1)

Publication Number Publication Date
CY1110292T1 true CY1110292T1 (el) 2015-01-14

Family

ID=31721742

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100217T CY1110292T1 (el) 2002-07-29 2010-03-09 Μεθοδοι για τη θεραπευτικη αντιμετωπιση αυτοανοσων νοσων με ενωσεις 2,4-πυριμιδινοδιαμινης

Country Status (25)

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US (5) US7517886B2 (US07825116-20101102-C00007.png)
EP (1) EP1534286B1 (US07825116-20101102-C00007.png)
JP (2) JP2006514989A (US07825116-20101102-C00007.png)
CN (2) CN1678321A (US07825116-20101102-C00007.png)
AT (1) ATE451104T1 (US07825116-20101102-C00007.png)
AU (1) AU2003265336B8 (US07825116-20101102-C00007.png)
BR (1) BR0313059B8 (US07825116-20101102-C00007.png)
CA (1) CA2492325C (US07825116-20101102-C00007.png)
CY (1) CY1110292T1 (US07825116-20101102-C00007.png)
DE (1) DE60330466D1 (US07825116-20101102-C00007.png)
DK (1) DK1534286T3 (US07825116-20101102-C00007.png)
ES (2) ES2445208T3 (US07825116-20101102-C00007.png)
HK (2) HK1079978A1 (US07825116-20101102-C00007.png)
HR (1) HRP20050089B1 (US07825116-20101102-C00007.png)
IL (3) IL166241A0 (US07825116-20101102-C00007.png)
IS (1) IS2923B (US07825116-20101102-C00007.png)
MX (1) MXPA05001096A (US07825116-20101102-C00007.png)
NO (1) NO332550B1 (US07825116-20101102-C00007.png)
NZ (1) NZ537752A (US07825116-20101102-C00007.png)
PL (1) PL216744B1 (US07825116-20101102-C00007.png)
RS (1) RS51752B (US07825116-20101102-C00007.png)
RU (1) RU2659777C9 (US07825116-20101102-C00007.png)
SE (1) SE0500203L (US07825116-20101102-C00007.png)
SG (1) SG176311A1 (US07825116-20101102-C00007.png)
WO (1) WO2004014382A1 (US07825116-20101102-C00007.png)

Families Citing this family (177)

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Publication number Priority date Publication date Assignee Title
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
CN1678321A (zh) 2002-07-29 2005-10-05 里格尔药品股份有限公司 用2,4－嘧啶二胺化合物治疗或者预防自体免疫性疾病的方法
AU2003288198A1 (en) * 2002-11-28 2004-06-18 Schering Aktiengesellschaft CHK-,PDK- and AKT-inhibitory pyrimidines, their production and use as pharmaceutical agents
UA80767C2 (en) * 2002-12-20 2007-10-25 Pfizer Prod Inc Pyrimidine derivatives for the treatment of abnormal cell growth
CL2004000303A1 (es) * 2003-02-20 2005-04-08 Tibotec Pharm Ltd Compuestos derivados de pirimidinas y triazinas; proceso de preparacion; composicion farmaceutica; y su uso para inhibir la replicacion del vih.
AU2004261484A1 (en) * 2003-07-30 2005-02-10 Cyclacel Limited 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
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