CR7235A - Inhibidores beta- amino tetrahidroimidazol (1,2-a) pirazinas y tetrahidrotrioazolo (4,3-a) pirazinas como depetidil peptidasa para el tratamiento o prevencion de la diabetes - Google Patents

Inhibidores beta- amino tetrahidroimidazol (1,2-a) pirazinas y tetrahidrotrioazolo (4,3-a) pirazinas como depetidil peptidasa para el tratamiento o prevencion de la diabetes

Info

Publication number
CR7235A
CR7235A CR7235A CR7235A CR7235A CR 7235 A CR7235 A CR 7235A CR 7235 A CR7235 A CR 7235A CR 7235 A CR7235 A CR 7235A CR 7235 A CR7235 A CR 7235A
Authority
CR
Costa Rica
Prior art keywords
diabetes
inhibitors
prevention
treatment
peptidase
Prior art date
Application number
CR7235A
Other languages
English (en)
Spanish (es)
Inventor
Scott D Edmondson
H Fisher Michael
Dooseop Kim
Maccos Malcom
Xu Jinyou
R Parmee Emma
E Weber Ann
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23172273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR7235(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CR7235A publication Critical patent/CR7235A/es

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P5/00—Drugs for disorders of the endocrine system
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    • A61P5/28—Antiandrogens
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
CR7235A 2001-07-06 2004-01-22 Inhibidores beta- amino tetrahidroimidazol (1,2-a) pirazinas y tetrahidrotrioazolo (4,3-a) pirazinas como depetidil peptidasa para el tratamiento o prevencion de la diabetes CR7235A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30347401P 2001-07-06 2001-07-06

Publications (1)

Publication Number Publication Date
CR7235A true CR7235A (es) 2006-05-31

Family

ID=23172273

Family Applications (1)

Application Number Title Priority Date Filing Date
CR7235A CR7235A (es) 2001-07-06 2004-01-22 Inhibidores beta- amino tetrahidroimidazol (1,2-a) pirazinas y tetrahidrotrioazolo (4,3-a) pirazinas como depetidil peptidasa para el tratamiento o prevencion de la diabetes

Country Status (45)

Country Link
US (9) US7125873B2 (OSRAM)
EP (4) EP2292232B1 (OSRAM)
JP (1) JP3762407B2 (OSRAM)
KR (1) KR100606871B1 (OSRAM)
CN (2) CN1861077A (OSRAM)
AR (1) AR036114A1 (OSRAM)
AT (2) ATE321048T1 (OSRAM)
AU (1) AU2002320303B2 (OSRAM)
BE (1) BE2007C047I2 (OSRAM)
BG (1) BG108493A (OSRAM)
BR (1) BRPI0210866B8 (OSRAM)
CA (1) CA2450740C (OSRAM)
CR (1) CR7235A (OSRAM)
CY (3) CY2007019I2 (OSRAM)
DE (4) DE60210093T2 (OSRAM)
DK (2) DK1412357T3 (OSRAM)
DO (1) DOP2002000438A (OSRAM)
EA (2) EA012701B1 (OSRAM)
EC (1) ECSP044935A (OSRAM)
ES (2) ES2259713T3 (OSRAM)
FR (2) FR07C0041I2 (OSRAM)
GE (2) GEP20063734B (OSRAM)
HR (1) HRP20031098B1 (OSRAM)
HU (2) HU225695B1 (OSRAM)
IL (3) IL159109A0 (OSRAM)
IS (2) IS2218B (OSRAM)
JO (1) JO2230B1 (OSRAM)
LT (1) LTC1412357I2 (OSRAM)
LU (2) LUC91360I2 (OSRAM)
MA (1) MA27053A1 (OSRAM)
ME (1) ME00439B (OSRAM)
MX (1) MXPA04000018A (OSRAM)
MY (1) MY127961A (OSRAM)
NL (2) NL300287I2 (OSRAM)
NO (4) NO321999B1 (OSRAM)
NZ (1) NZ529833A (OSRAM)
PE (1) PE20030654A1 (OSRAM)
PL (1) PL196278B6 (OSRAM)
PT (2) PT1412357E (OSRAM)
RS (1) RS50737B (OSRAM)
SI (1) SI1412357T1 (OSRAM)
TW (1) TWI226331B (OSRAM)
UA (1) UA74912C2 (OSRAM)
WO (1) WO2003004498A1 (OSRAM)
ZA (1) ZA200309294B (OSRAM)

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