TW200500338A - Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes - Google Patents

Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes

Info

Publication number
TW200500338A
TW200500338A TW092136707A TW92136707A TW200500338A TW 200500338 A TW200500338 A TW 200500338A TW 092136707 A TW092136707 A TW 092136707A TW 92136707 A TW92136707 A TW 92136707A TW 200500338 A TW200500338 A TW 200500338A
Authority
TW
Taiwan
Prior art keywords
diabetes
dipeptidyl peptidase
prevention
treatment
phenylalanine derivatives
Prior art date
Application number
TW092136707A
Other languages
Chinese (zh)
Inventor
Vincent J Colandrea
Scott D Edmondson
Robert J Mathvink
Anthony Mastracchio
Ann E Weber
Jinyou Xu
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of TW200500338A publication Critical patent/TW200500338A/en

Links

Abstract

The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
TW092136707A 2003-06-19 2003-12-24 Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes TW200500338A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50123203P 2003-06-19 2003-06-19

Publications (1)

Publication Number Publication Date
TW200500338A true TW200500338A (en) 2005-01-01

Family

ID=40261513

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092136707A TW200500338A (en) 2003-06-19 2003-12-24 Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes

Country Status (4)

Country Link
AR (1) AR042654A1 (en)
CL (1) CL2003002751A1 (en)
PE (1) PE20041058A1 (en)
TW (1) TW200500338A (en)

Also Published As

Publication number Publication date
AR042654A1 (en) 2005-06-29
CL2003002751A1 (en) 2005-04-08
PE20041058A1 (en) 2005-02-07

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