TW200500338A - Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes - Google Patents

Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes

Info

Publication number
TW200500338A
TW200500338A TW092136707A TW92136707A TW200500338A TW 200500338 A TW200500338 A TW 200500338A TW 092136707 A TW092136707 A TW 092136707A TW 92136707 A TW92136707 A TW 92136707A TW 200500338 A TW200500338 A TW 200500338A
Authority
TW
Taiwan
Prior art keywords
diabetes
dipeptidyl peptidase
prevention
treatment
phenylalanine derivatives
Prior art date
Application number
TW092136707A
Other languages
Chinese (zh)
Inventor
Vincent J Colandrea
Scott D Edmondson
Robert J Mathvink
Anthony Mastracchio
Ann E Weber
Jinyou Xu
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of TW200500338A publication Critical patent/TW200500338A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
TW092136707A 2003-06-19 2003-12-24 Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes TW200500338A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50123203P 2003-06-19 2003-06-19

Publications (1)

Publication Number Publication Date
TW200500338A true TW200500338A (en) 2005-01-01

Family

ID=40261513

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092136707A TW200500338A (en) 2003-06-19 2003-12-24 Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes

Country Status (4)

Country Link
AR (1) AR042654A1 (en)
CL (1) CL2003002751A1 (en)
PE (1) PE20041058A1 (en)
TW (1) TW200500338A (en)

Also Published As

Publication number Publication date
AR042654A1 (en) 2005-06-29
PE20041058A1 (en) 2005-02-07
CL2003002751A1 (en) 2005-04-08

Similar Documents

Publication Publication Date Title
PL376822A1 (en) Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2004050022A3 (en) Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
EP1624874A4 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2004112701A3 (en) Cyclohexylglycine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
HK1086265A1 (en) Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
EP1651623A4 (en) Hexahydrodiazepinones as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1385508A4 (en) Dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
EP1554256A4 (en) Piperidino pyrimidine dipeptidyl peptidase inhibitors for the treatment of diabetes
WO2004069162A3 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2004064778A3 (en) 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2003082817A3 (en) Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2005044195A3 (en) Fused phenylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1784188A4 (en) Fused triazole derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1635818A4 (en) Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
JO2230B1 (en) Beta amino heterocyclic dipeptidyl peptidase inhibitors for the treatmetn or prevention of diabetes
EP1796669A4 (en) Aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1554280A4 (en) Antidiabetic beta-amino heterocyclic dipeptidyl peptidase inhibitors
EP1819674A4 (en) Fused aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1888066A4 (en) Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
EP1921917A4 (en) Fused aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
TW200500338A (en) Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
MY138965A (en) Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
JO2396B1 (en) bata-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes