SI2736909T1 - Proces za pripravo sitagliptina in njegovih farmacevtsko sprejemljivih soli - Google Patents

Proces za pripravo sitagliptina in njegovih farmacevtsko sprejemljivih soli

Info

Publication number
SI2736909T1
SI2736909T1 SI201230989T SI201230989T SI2736909T1 SI 2736909 T1 SI2736909 T1 SI 2736909T1 SI 201230989 T SI201230989 T SI 201230989T SI 201230989 T SI201230989 T SI 201230989T SI 2736909 T1 SI2736909 T1 SI 2736909T1
Authority
SI
Slovenia
Prior art keywords
sitagliptin
preparation
pharmaceutically acceptable
acceptable salts
salts
Prior art date
Application number
SI201230989T
Other languages
English (en)
Inventor
Silvo Zupancic
Rok Zupet
Original Assignee
Farma Grs, D.O.O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farma Grs, D.O.O. filed Critical Farma Grs, D.O.O.
Publication of SI2736909T1 publication Critical patent/SI2736909T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
SI201230989T 2011-07-27 2012-07-27 Proces za pripravo sitagliptina in njegovih farmacevtsko sprejemljivih soli SI2736909T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI201100277 2011-07-27
EP12740505.8A EP2736909B1 (en) 2011-07-27 2012-07-27 Process for the preparation of sitagliptin and its pharmaceutically acceptable salts
PCT/EP2012/003214 WO2013013833A1 (en) 2011-07-27 2012-07-27 Process for the preparation of sitagliptin and its pharmaceutically acceptable salts

Publications (1)

Publication Number Publication Date
SI2736909T1 true SI2736909T1 (sl) 2017-08-31

Family

ID=46583953

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201230989T SI2736909T1 (sl) 2011-07-27 2012-07-27 Proces za pripravo sitagliptina in njegovih farmacevtsko sprejemljivih soli

Country Status (4)

Country Link
EP (1) EP2736909B1 (sl)
EA (1) EA024688B1 (sl)
SI (1) SI2736909T1 (sl)
WO (1) WO2013013833A1 (sl)

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IN2013MU00916A (sl) 2013-03-20 2015-06-26 Cadila Healthcare Ltd
WO2015001568A2 (en) * 2013-07-01 2015-01-08 Laurus Labs Private Limited Sitagliptin lipoate salt, process for the preparation and pharmaceutical composition thereof
WO2015145333A1 (en) 2014-03-26 2015-10-01 Sun Pharmaceutical Industries Limited Process for the preparation of sitagliptin and its intermediate
CN106124667B (zh) * 2016-08-29 2018-07-31 上海应用技术学院 一种分离测定西格列汀有关物质的方法
CN112209931A (zh) * 2019-07-10 2021-01-12 浙江昌海制药有限公司 一种提高西格列汀收率和纯度的工艺方法
CN113149991A (zh) * 2020-12-31 2021-07-23 浙江美诺华药物化学有限公司 西他列汀游离碱及西他列汀磷酸盐一水合物的合成方法

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Also Published As

Publication number Publication date
EA024688B1 (ru) 2016-10-31
EP2736909A1 (en) 2014-06-04
EP2736909B1 (en) 2017-03-29
EA201490383A1 (ru) 2014-06-30
WO2013013833A1 (en) 2013-01-31

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