AU2002327627B2 - Inhibitors of histone deacetylase - Google Patents

Inhibitors of histone deacetylase Download PDF

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Publication number
AU2002327627B2
AU2002327627B2 AU2002327627A AU2002327627A AU2002327627B2 AU 2002327627 B2 AU2002327627 B2 AU 2002327627B2 AU 2002327627 A AU2002327627 A AU 2002327627A AU 2002327627 A AU2002327627 A AU 2002327627A AU 2002327627 B2 AU2002327627 B2 AU 2002327627B2
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Prior art keywords
amino
nmr
phenyl
compound according
ppm
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AU2002327627A1 (en
Inventor
Giliane Bouchain
Daniel Delorme
Sylvie Frechette
Silvana Leit
Oscar Moradel
Stephane Raeppel
Arkadii Vaisburg
Soon Hyung Woo
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Methylgene Inc
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Methylgene Inc
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Priority to AU2006252047A priority Critical patent/AU2006252047B2/en
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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    • C07C237/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
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    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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KR20100107509A (ko) 2010-10-05
CN101851173A (zh) 2010-10-06
CA2465978C (en) 2015-04-07
CA2465978A1 (en) 2003-03-27
CN1578663B (zh) 2011-05-25

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