TW585857B - Prodrugs of COX-2 inhibitors - Google Patents

Prodrugs of COX-2 inhibitors Download PDF

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Publication number
TW585857B
TW585857B TW086107093A TW86107093A TW585857B TW 585857 B TW585857 B TW 585857B TW 086107093 A TW086107093 A TW 086107093A TW 86107093 A TW86107093 A TW 86107093A TW 585857 B TW585857 B TW 585857B
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Taiwan
Prior art keywords
phenyl
methyl
sulfonyl
sodium salt
phenylisoxazol
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TW086107093A
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English (en)
Chinese (zh)
Inventor
James W Malecha
Stephen Bertenshaw
Matthew J Graneto
Jeffrey Carter
Jinglin Li
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Searle & Co
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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TW086107093A 1996-04-12 1997-05-26 Prodrugs of COX-2 inhibitors TW585857B (en)

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