TW509674B - N-(substituted glycyl)-2-cyanopyrrolidine derivatives - Google Patents

N-(substituted glycyl)-2-cyanopyrrolidine derivatives Download PDF

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Publication number
TW509674B
TW509674B TW088121371A TW88121371A TW509674B TW 509674 B TW509674 B TW 509674B TW 088121371 A TW088121371 A TW 088121371A TW 88121371 A TW88121371 A TW 88121371A TW 509674 B TW509674 B TW 509674B
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TW
Taiwan
Prior art keywords
amino
patent application
scope
cyano
adamantyl
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Application number
TW088121371A
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English (en)
Chinese (zh)
Inventor
Edwin Bernard Villhauer
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Novartis Ag
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW088121371A 1998-12-10 1999-12-07 N-(substituted glycyl)-2-cyanopyrrolidine derivatives TW509674B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20906898A 1998-12-10 1998-12-10

Publications (1)

Publication Number Publication Date
TW509674B true TW509674B (en) 2002-11-11

Family

ID=22777194

Family Applications (1)

Application Number Title Priority Date Filing Date
TW088121371A TW509674B (en) 1998-12-10 1999-12-07 N-(substituted glycyl)-2-cyanopyrrolidine derivatives

Country Status (34)

Country Link
US (1) US6166063A (show.php)
EP (1) EP1137635B1 (show.php)
JP (2) JP3681110B2 (show.php)
KR (2) KR100509311B1 (show.php)
CN (1) CN1160330C (show.php)
AR (1) AR023719A1 (show.php)
AT (1) ATE307112T1 (show.php)
BR (1) BRPI9915985B8 (show.php)
CA (1) CA2350609C (show.php)
CO (1) CO5150173A1 (show.php)
CY (3) CY1105355T1 (show.php)
CZ (1) CZ299151B6 (show.php)
DE (3) DE69927844T2 (show.php)
DK (1) DK1137635T3 (show.php)
ES (1) ES2251847T3 (show.php)
FR (1) FR08C0005I2 (show.php)
HK (1) HK1040394B (show.php)
HU (1) HU226769B1 (show.php)
ID (1) ID28796A (show.php)
IL (2) IL143091A0 (show.php)
LU (2) LU91409I2 (show.php)
MY (1) MY123244A (show.php)
NL (2) NL300333I2 (show.php)
NO (3) NO318741B1 (show.php)
NZ (1) NZ511935A (show.php)
PE (1) PE20001317A1 (show.php)
PL (1) PL199443B1 (show.php)
RU (1) RU2251544C2 (show.php)
SK (1) SK286635B6 (show.php)
TR (1) TR200101478T2 (show.php)
TW (1) TW509674B (show.php)
UY (1) UY25843A1 (show.php)
WO (1) WO2000034241A1 (show.php)
ZA (1) ZA200104581B (show.php)

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