TW202523682A - 共有之gata3相關之腫瘤特異性新抗原 - Google Patents

共有之gata3相關之腫瘤特異性新抗原

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Publication number
TW202523682A
TW202523682A TW114108178A TW114108178A TW202523682A TW 202523682 A TW202523682 A TW 202523682A TW 114108178 A TW114108178 A TW 114108178A TW 114108178 A TW114108178 A TW 114108178A TW 202523682 A TW202523682 A TW 202523682A
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Taiwan
Prior art keywords
seq
tumor
composition
cell
specific
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TW114108178A
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English (en)
Chinese (zh)
Inventor
愛德華 F 弗里奇
尼爾 哈可漢
麥可 史帝芬 魯尼
沙奇 艾司霍克 蘇可拉
凱瑟琳 Ｊ 吳
帕汎 巴奇瑞迪
孫津
Original Assignee
美商博德研究所有限公司
美商達納 法伯癌症協會
美商通用醫院公司
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Application filed by 美商博德研究所有限公司, 美商達納 法伯癌症協會, 美商通用醫院公司 filed Critical 美商博德研究所有限公司
Publication of TW202523682A publication Critical patent/TW202523682A/zh

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    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001104—Epidermal growth factor receptors [EGFR]
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    • A61K39/0005—Vertebrate antigens
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    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/001148—Regulators of development
    • A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
    • A61K39/001151—Apoptosis related proteins, e.g. survivin or livin p53
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    • A61K39/0005—Vertebrate antigens
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    • A61K39/0005—Vertebrate antigens
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    • A61K39/001154—Enzymes
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    • A—HUMAN NECESSITIES
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    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001196—Fusion proteins originating from gene translocation in cancer cells
    • A61K39/001197—Breakpoint cluster region-abelson tyrosine kinase [BCR-ABL]
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation
    • G01N2800/7028—Cancer
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
TW114108178A 2015-05-20 2016-05-20 共有之gata3相關之腫瘤特異性新抗原 TW202523682A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562179877P 2015-05-20 2015-05-20
US62/179,877 2015-05-20
US201662389377P 2016-02-23 2016-02-23
US62/389,377 2016-02-23

Publications (1)

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TW202523682A true TW202523682A (zh) 2025-06-16

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TW114108178A TW202523682A (zh) 2015-05-20 2016-05-20 共有之gata3相關之腫瘤特異性新抗原
TW112105056A TWI878795B (zh) 2015-05-20 2016-05-20 共有之gata3相關之腫瘤特異性新抗原
TW105115840A TWI806815B (zh) 2015-05-20 2016-05-20 共有之ｇａｔａ３相關之腫瘤特異性新抗原

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TW112105056A TWI878795B (zh) 2015-05-20 2016-05-20 共有之gata3相關之腫瘤特異性新抗原
TW105115840A TWI806815B (zh) 2015-05-20 2016-05-20 共有之ｇａｔａ３相關之腫瘤特異性新抗原

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US (2) US10835585B2 (enExample)
EP (1) EP3297660A2 (enExample)
JP (3) JP6913032B2 (enExample)
KR (2) KR20240166604A (enExample)
CN (1) CN108025048B (enExample)
AU (3) AU2016264623B2 (enExample)
BR (1) BR112017024797A2 (enExample)
CA (1) CA2986235A1 (enExample)
CL (2) CL2017002945A1 (enExample)
CO (1) CO2017012835A2 (enExample)
CR (3) CR20200476A (enExample)
EC (1) ECSP17084137A (enExample)
HK (1) HK1252267A1 (enExample)
IL (3) IL294183B2 (enExample)
MX (3) MX2017014700A (enExample)
MY (1) MY190974A (enExample)
PE (1) PE20180670A1 (enExample)
PH (1) PH12017502321A1 (enExample)
RU (1) RU2733754C2 (enExample)
TW (3) TW202523682A (enExample)
WO (1) WO2016187508A2 (enExample)

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