NZ207659A - Production of expression plasmid:genes for expression of selectable characteristic and heterologous compound under direction of bacterial promoter - Google Patents

Production of expression plasmid:genes for expression of selectable characteristic and heterologous compound under direction of bacterial promoter

Info

Publication number
NZ207659A
NZ207659A NZ207659A NZ20765981A NZ207659A NZ 207659 A NZ207659 A NZ 207659A NZ 207659 A NZ207659 A NZ 207659A NZ 20765981 A NZ20765981 A NZ 20765981A NZ 207659 A NZ207659 A NZ 207659A
Authority
NZ
New Zealand
Prior art keywords
plasmid
expression
promoter
trp
gene
Prior art date
Application number
NZ207659A
Other languages
English (en)
Inventor
D G Kleid
D G Yansura
H L Heyneker
G F Miozzari
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NZ207659A publication Critical patent/NZ207659A/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ207659A 1980-03-24 1981-03-23 Production of expression plasmid:genes for expression of selectable characteristic and heterologous compound under direction of bacterial promoter NZ207659A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13329680A 1980-03-24 1980-03-24
NZ196584A NZ196584A (en) 1980-03-24 1981-03-23 Recombinant dna method for polypeptide production:plasmidic expression vehicle comprising bacterial trp promoter-operator system

Publications (1)

Publication Number Publication Date
NZ207659A true NZ207659A (en) 1985-12-13

Family

ID=22457906

Family Applications (3)

Application Number Title Priority Date Filing Date
NZ207659A NZ207659A (en) 1980-03-24 1981-03-23 Production of expression plasmid:genes for expression of selectable characteristic and heterologous compound under direction of bacterial promoter
NZ207660A NZ207660A (en) 1980-03-24 1981-03-23 Method of cleaving double-stranded dna at specific point;plasmid p thy alpha 7 delta 1 delta 4
NZ196584A NZ196584A (en) 1980-03-24 1981-03-23 Recombinant dna method for polypeptide production:plasmidic expression vehicle comprising bacterial trp promoter-operator system

Family Applications After (2)

Application Number Title Priority Date Filing Date
NZ207660A NZ207660A (en) 1980-03-24 1981-03-23 Method of cleaving double-stranded dna at specific point;plasmid p thy alpha 7 delta 1 delta 4
NZ196584A NZ196584A (en) 1980-03-24 1981-03-23 Recombinant dna method for polypeptide production:plasmidic expression vehicle comprising bacterial trp promoter-operator system

Country Status (35)

Country Link
US (2) US5888808A (mber)
EP (3) EP0086548B1 (mber)
JP (3) JPH0724582B2 (mber)
KR (2) KR830005351A (mber)
AR (1) AR248050A1 (mber)
AT (3) ATE34183T1 (mber)
AU (3) AU542640B2 (mber)
BG (3) BG46005A3 (mber)
BR (1) BR8101712A (mber)
CA (2) CA1198068A (mber)
CS (3) CS238645B2 (mber)
DD (3) DD204494A5 (mber)
DE (5) DE3176205D1 (mber)
DK (1) DK173085B1 (mber)
DZ (1) DZ278A1 (mber)
ES (3) ES500617A0 (mber)
FI (3) FI853488A7 (mber)
FR (2) FR2480781B1 (mber)
GB (1) GB2073203B (mber)
GR (1) GR74818B (mber)
HU (1) HU195534B (mber)
IE (3) IE51892B1 (mber)
IL (3) IL71885A (mber)
IT (1) IT1144324B (mber)
MX (1) MX7689E (mber)
MY (1) MY8500896A (mber)
NO (3) NO810986L (mber)
NZ (3) NZ207659A (mber)
OA (1) OA06774A (mber)
PH (4) PH17537A (mber)
PL (2) PL147727B1 (mber)
PT (1) PT72716B (mber)
YU (2) YU45534B (mber)
ZA (1) ZA811368B (mber)
ZW (1) ZW5481A1 (mber)

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