MX379946B - Composiciones farmacéuticas de ácido 3-(6-(1-(2,2 difluorobenzo[d][1,3]dioxol-5-il) ciclopropancarboxamido)-3-metilpiridin-2-il)benzoico y su administración. - Google Patents

Composiciones farmacéuticas de ácido 3-(6-(1-(2,2 difluorobenzo[d][1,3]dioxol-5-il) ciclopropancarboxamido)-3-metilpiridin-2-il)benzoico y su administración.

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Publication number
MX379946B
MX379946B MX2018014775A MX2018014775A MX379946B MX 379946 B MX379946 B MX 379946B MX 2018014775 A MX2018014775 A MX 2018014775A MX 2018014775 A MX2018014775 A MX 2018014775A MX 379946 B MX379946 B MX 379946B
Authority
MX
Mexico
Prior art keywords
cyclopropanecarboxamido
difluorobenzo
dioxol
benzoic acid
administration
Prior art date
Application number
MX2018014775A
Other languages
English (en)
Inventor
Christopher Ryan Young
Irina Nikolaevna Kadiyala
Marinus Jacobus Verwijs
Ritu Rohit Kaushik
Rossitza Gueorguieva Alargova
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47075277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX379946(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of MX379946B publication Critical patent/MX379946B/es

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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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Abstract

Una composición farmacéutica que comprende el Compuesto 1, ácido (3-(6-(1-(2,2-difluorobenzo[d] [1,3]dioxol-5-il)ciclopropancarboxamido)-3-metilpiridin-2-il)benzoico), y al menos un excipiente seleccionado de: un relleno, un diluyente, un disgregante, un agente tensioactivo, un aglutinante, un deslizante y un lubricante, la composición siendo adecuada para administración oral a una paciente en la necesidad de esto para tratar una enfermedad mediada por CFTR tal como Fibrosis Cística. Métodos para tratar un paciente en a necesidad de esto incluyen la administración de una formulación farmacéutica oral del Compuesto 1 al paciente.
MX2018014775A 2010-04-07 2011-04-07 Composiciones farmacéuticas de ácido 3-(6-(1-(2,2 difluorobenzo[d][1,3]dioxol-5-il) ciclopropancarboxamido)-3-metilpiridin-2-il)benzoico y su administración. MX379946B (es)

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PCT/US2011/031519 WO2011127241A2 (en) 2010-04-07 2011-04-07 Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyriodin-2-yl)benzoic acid and administration thereof

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MX2012011656A MX364937B (es) 2010-04-07 2011-04-07 Composiciones farmaceuticas de acido 3-(6-(1-(2,2-difluorobenzo [d][1,3]dioxol-5-il)ciclopropancarboxamido)-3-metilpiridin-2-il) benzoico y su administracion.

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