HUE038854T2 - Cisztás fibrózis transzmembrán konduktancia regulátor modulátorai - Google Patents

Cisztás fibrózis transzmembrán konduktancia regulátor modulátorai

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Publication number
HUE038854T2
HUE038854T2 HUE10710748A HUE10710748A HUE038854T2 HU E038854 T2 HUE038854 T2 HU E038854T2 HU E10710748 A HUE10710748 A HU E10710748A HU E10710748 A HUE10710748 A HU E10710748A HU E038854 T2 HUE038854 T2 HU E038854T2
Authority
HU
Hungary
Prior art keywords
modulators
cystic fibrosis
fibrosis transmembrane
conductance regulator
transmembrane conductance
Prior art date
Application number
HUE10710748A
Other languages
English (en)
Inventor
Xiaoqing Yang
Ruah Sara Hadida
Peter Grootenhuis
Goor Fredrick Van
Martyn Botfield
Gregor Zlokarnik
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of HUE038854T2 publication Critical patent/HUE038854T2/hu

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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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HUE10710748A 2009-03-20 2010-03-19 Cisztás fibrózis transzmembrán konduktancia regulátor modulátorai HUE038854T2 (hu)

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US16213009P 2009-03-20 2009-03-20

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HUE038854T2 true HUE038854T2 (hu) 2018-12-28

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US (4) US8614325B2 (hu)
EP (1) EP2408749B1 (hu)
JP (3) JP5636418B2 (hu)
CN (1) CN102361856A (hu)
AU (1) AU2010226393B2 (hu)
BR (1) BRPI1012549B8 (hu)
CA (1) CA2755969C (hu)
CY (1) CY1120593T1 (hu)
DK (1) DK2408749T3 (hu)
ES (1) ES2683633T3 (hu)
HR (1) HRP20181261T1 (hu)
HU (1) HUE038854T2 (hu)
IL (1) IL215261A (hu)
LT (1) LT2408749T (hu)
MX (1) MX2011009868A (hu)
NZ (1) NZ595151A (hu)
PL (1) PL2408749T3 (hu)
PT (1) PT2408749T (hu)
RU (1) RU2518897C2 (hu)
SI (1) SI2408749T1 (hu)
WO (1) WO2010108155A1 (hu)
ZA (1) ZA201106618B (hu)

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US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
CA2537841A1 (en) 2003-09-06 2005-03-24 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
PL1773816T3 (pl) 2004-06-24 2015-06-30 Vertex Pharma Modulatory transporterów posiadających kasetę wiążącą ATP
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