MX2019009841A - Compuestos y metodos para el tratamiento de la colangitis biliar primaria. - Google Patents

Compuestos y metodos para el tratamiento de la colangitis biliar primaria.

Info

Publication number
MX2019009841A
MX2019009841A MX2019009841A MX2019009841A MX2019009841A MX 2019009841 A MX2019009841 A MX 2019009841A MX 2019009841 A MX2019009841 A MX 2019009841A MX 2019009841 A MX2019009841 A MX 2019009841A MX 2019009841 A MX2019009841 A MX 2019009841A
Authority
MX
Mexico
Prior art keywords
treatment
primary biliary
methods
biliary cholangitis
compound
Prior art date
Application number
MX2019009841A
Other languages
English (en)
Spanish (es)
Inventor
Geraldine Lassen Cheryl
Mark Jones Robert
Liu Que
J Christopher Ronald
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of MX2019009841A publication Critical patent/MX2019009841A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2019009841A 2017-02-16 2018-02-16 Compuestos y metodos para el tratamiento de la colangitis biliar primaria. MX2019009841A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762459916P 2017-02-16 2017-02-16
US201762502129P 2017-05-05 2017-05-05
US201762506906P 2017-05-16 2017-05-16
PCT/US2018/000091 WO2018151873A1 (en) 2017-02-16 2018-02-16 Compounds and methods for treatment of primary biliary cholangitis

Publications (1)

Publication Number Publication Date
MX2019009841A true MX2019009841A (es) 2020-01-30

Family

ID=61873875

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019009841A MX2019009841A (es) 2017-02-16 2018-02-16 Compuestos y metodos para el tratamiento de la colangitis biliar primaria.

Country Status (10)

Country Link
US (2) US11534424B2 (OSRAM)
EP (1) EP3582772A1 (OSRAM)
JP (1) JP2020507611A (OSRAM)
KR (1) KR20190116416A (OSRAM)
CN (1) CN110520124A (OSRAM)
AU (1) AU2018220521A1 (OSRAM)
CA (1) CA3053418A1 (OSRAM)
MA (1) MA47504A (OSRAM)
MX (1) MX2019009841A (OSRAM)
WO (1) WO2018151873A1 (OSRAM)

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SG10201500639TA (en) 2010-01-27 2015-03-30 Arena Pharm Inc Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
ES2995737T3 (en) 2015-01-06 2025-02-11 Arena Pharm Inc Compound for use in treating conditions related to the s1p1 receptor
MA42807A (fr) 2015-06-22 2018-07-25 Arena Pharm Inc Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1
WO2018151873A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
CA3053416A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
EP3801459B1 (en) 2018-06-06 2024-08-07 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor
US20210386706A1 (en) * 2018-10-03 2021-12-16 Arena Pharmaceuticals, Inc. Methods for the treatment of scleroderma
KR102824401B1 (ko) * 2018-11-30 2025-06-25 아레나 파마슈티칼스, 인크. S1p1 수용체와 관련된 병태의 치료 방법
CN115066242A (zh) * 2020-01-06 2022-09-16 艾尼纳制药公司 治疗与s1p1受体相关的病症的方法
KR20220140762A (ko) * 2020-02-10 2022-10-18 장피트 엘라피브라노에 의한 원발 담즙성 담관염의 치료
WO2025177319A2 (en) * 2024-02-22 2025-08-28 Msn Laboratories Private Limited, R&D Center Solid state forms of L-Arginine, (3R)-7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydrocyclopent[b]indole-3-acetate and processes for preparation thereof

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WO2018151873A1 (en) 2018-08-23
EP3582772A1 (en) 2019-12-25
AU2018220521A1 (en) 2019-09-05
US20230149353A1 (en) 2023-05-18
JP2020507611A (ja) 2020-03-12
US11534424B2 (en) 2022-12-27
US20200000770A1 (en) 2020-01-02
MA47504A (fr) 2019-12-25
KR20190116416A (ko) 2019-10-14
CA3053418A1 (en) 2018-08-23

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