MA27053A1 - Beta-amino tetrahydroimidazo(1,2-a)pyrazines et tetrahydrotriazolo (4,3-a)pyrazines comme inhibiteurs de la dipeptidyl peptidase pour le traitement ou la prevention du diabete - Google Patents

Beta-amino tetrahydroimidazo(1,2-a)pyrazines et tetrahydrotriazolo (4,3-a)pyrazines comme inhibiteurs de la dipeptidyl peptidase pour le traitement ou la prevention du diabete

Info

Publication number
MA27053A1
MA27053A1 MA27501A MA27501A MA27053A1 MA 27053 A1 MA27053 A1 MA 27053A1 MA 27501 A MA27501 A MA 27501A MA 27501 A MA27501 A MA 27501A MA 27053 A1 MA27053 A1 MA 27053A1
Authority
MA
Morocco
Prior art keywords
pyrazines
diabetes
prevention
treatment
tetrahydrotriazolo
Prior art date
Application number
MA27501A
Other languages
English (en)
French (fr)
Inventor
D Edmondson Scott
H Fisher Michael
Kim Dooseop
Maccoss Malcolm
R Parmee Emma
E Weber Ann
Xu Jinyou
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23172273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA27053(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of MA27053A1 publication Critical patent/MA27053A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/28—Insulins
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
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  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
MA27501A 2001-07-06 2004-01-26 Beta-amino tetrahydroimidazo(1,2-a)pyrazines et tetrahydrotriazolo (4,3-a)pyrazines comme inhibiteurs de la dipeptidyl peptidase pour le traitement ou la prevention du diabete MA27053A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30347401P 2001-07-06 2001-07-06

Publications (1)

Publication Number Publication Date
MA27053A1 true MA27053A1 (fr) 2004-12-20

Family

ID=23172273

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27501A MA27053A1 (fr) 2001-07-06 2004-01-26 Beta-amino tetrahydroimidazo(1,2-a)pyrazines et tetrahydrotriazolo (4,3-a)pyrazines comme inhibiteurs de la dipeptidyl peptidase pour le traitement ou la prevention du diabete

Country Status (45)

Country Link
US (9) US7125873B2 (enExample)
EP (4) EP2226324A1 (enExample)
JP (1) JP3762407B2 (enExample)
KR (1) KR100606871B1 (enExample)
CN (2) CN1861077A (enExample)
AR (1) AR036114A1 (enExample)
AT (2) ATE321048T1 (enExample)
AU (1) AU2002320303B2 (enExample)
BE (1) BE2007C047I2 (enExample)
BG (1) BG108493A (enExample)
BR (1) BRPI0210866B8 (enExample)
CA (1) CA2450740C (enExample)
CR (1) CR7235A (enExample)
CY (3) CY2007019I2 (enExample)
DE (4) DE60236767D1 (enExample)
DK (2) DK1412357T3 (enExample)
DO (1) DOP2002000438A (enExample)
EA (2) EA012701B1 (enExample)
EC (1) ECSP044935A (enExample)
ES (2) ES2259713T3 (enExample)
FR (2) FR07C0041I2 (enExample)
GE (2) GEP20053734B (enExample)
HR (1) HRP20031098B1 (enExample)
HU (2) HU225695B1 (enExample)
IL (3) IL159109A0 (enExample)
IS (2) IS2218B (enExample)
JO (1) JO2230B1 (enExample)
LT (1) LTC1412357I2 (enExample)
LU (2) LUC91360I2 (enExample)
MA (1) MA27053A1 (enExample)
ME (1) ME00439B (enExample)
MX (1) MXPA04000018A (enExample)
MY (1) MY127961A (enExample)
NL (2) NL300287I2 (enExample)
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PL (1) PL196278B6 (enExample)
PT (2) PT1412357E (enExample)
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UA (1) UA74912C2 (enExample)
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ZA (1) ZA200309294B (enExample)

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