KR100848429B1 - 치환된 알킬아민 유도체 및 그의 사용 방법 - Google Patents

치환된 알킬아민 유도체 및 그의 사용 방법 Download PDF

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KR100848429B1
KR100848429B1 KR1020037009274A KR20037009274A KR100848429B1 KR 100848429 B1 KR100848429 B1 KR 100848429B1 KR 1020037009274 A KR1020037009274 A KR 1020037009274A KR 20037009274 A KR20037009274 A KR 20037009274A KR 100848429 B1 KR100848429 B1 KR 100848429B1
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South Korea
Prior art keywords
amino
substituted
ylmethyl
boc
alkoxy
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KR1020037009274A
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Korean (ko)
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KR20030078067A (ko
Inventor
구오킹 첸
제프리 아담스
진 베미스
숀 부커
구올린 카이
마이클 크로간
루시안 디피에트로
셀리아 도밍궤즈
다니엘 엘바움
줄리 저메인
스테파니 쥔스-마이어
마이클 핸들리
키 후앙
조세프 엘. 킴
태-성 김
알렉산더 키젤료브
샤오후 오우양
비노드에프. 파텔
레온 엠. 스미스
마르키안 스텍
앤드류 태스커
닝 시
쉬민 슈
체스터 첸구앙 유안
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암겐 인코포레이티드
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Publication of KR20030078067A publication Critical patent/KR20030078067A/ko
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Publication of KR100848429B1 publication Critical patent/KR100848429B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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