JP6417419B2 - 免疫調節剤として有用な化合物 - Google Patents
免疫調節剤として有用な化合物 Download PDFInfo
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- JP6417419B2 JP6417419B2 JP2016540311A JP2016540311A JP6417419B2 JP 6417419 B2 JP6417419 B2 JP 6417419B2 JP 2016540311 A JP2016540311 A JP 2016540311A JP 2016540311 A JP2016540311 A JP 2016540311A JP 6417419 B2 JP6417419 B2 JP 6417419B2
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- methyl
- methoxy
- phenylphenyl
- phenyl
- amino
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- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A61K31/396—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
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- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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| RU2726206C2 (ru) | 2015-05-21 | 2020-07-09 | Кемосентрикс, Инк. | Модуляторы ccr2 |
| CN107709314A (zh) | 2015-06-11 | 2018-02-16 | 巴斯利尔药物国际股份公司 | 外排泵抑制剂及其治疗性用途 |
| US10745382B2 (en) * | 2015-10-15 | 2020-08-18 | Bristol-Myers Squibb Company | Compounds useful as immunomodulators |
| US20170107216A1 (en) | 2015-10-19 | 2017-04-20 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| MD3377488T2 (ro) * | 2015-11-19 | 2023-02-28 | Incyte Corp | Compuși heterociclici ca imunomodulatori |
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| ES2916874T3 (es) | 2015-12-17 | 2022-07-06 | Incyte Corp | Derivados de N-fenil-piridina-2-carboxamida y su uso como moduladores de la interacción proteína/proteína PD-1/PD-L1 |
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| TW200815377A (en) | 2006-04-24 | 2008-04-01 | Astellas Pharma Inc | Oxadiazolidinedione compound |
| US9321730B2 (en) * | 2007-08-21 | 2016-04-26 | The Hong Kong Polytechnic University | Method of making and administering quinoline derivatives as anti-cancer agents |
| TW200932219A (en) | 2007-10-24 | 2009-08-01 | Astellas Pharma Inc | Oxadiazolidinedione compound |
| WO2010059838A2 (en) * | 2008-11-20 | 2010-05-27 | Decode Genetics Ehf | Pde4 inhibitors selective for the long form of pde4 for treating inflammation and avoiding side effects |
| US20130022629A1 (en) * | 2010-01-04 | 2013-01-24 | Sharpe Arlene H | Modulators of Immunoinhibitory Receptor PD-1, and Methods of Use Thereof |
| US9850225B2 (en) | 2014-04-14 | 2017-12-26 | Bristol-Myers Squibb Company | Compounds useful as immunomodulators |
| US10745382B2 (en) | 2015-10-15 | 2020-08-18 | Bristol-Myers Squibb Company | Compounds useful as immunomodulators |
-
2014
- 2014-09-02 MX MX2016002544A patent/MX2016002544A/es unknown
- 2014-09-02 PE PE2016000338A patent/PE20160432A1/es not_active Application Discontinuation
- 2014-09-02 JP JP2016540311A patent/JP6417419B2/ja not_active Expired - Fee Related
- 2014-09-02 BR BR112016004194A patent/BR112016004194A8/pt not_active Application Discontinuation
- 2014-09-02 KR KR1020167008405A patent/KR102276644B1/ko not_active Expired - Fee Related
- 2014-09-02 CA CA2923184A patent/CA2923184A1/en not_active Abandoned
- 2014-09-02 WO PCT/US2014/053695 patent/WO2015034820A1/en not_active Ceased
- 2014-09-02 AU AU2014315457A patent/AU2014315457B2/en not_active Ceased
- 2014-09-02 ES ES14766086.4T patent/ES2642074T3/es active Active
- 2014-09-02 EA EA201690316A patent/EA029901B1/ru not_active IP Right Cessation
- 2014-09-02 EP EP14766086.4A patent/EP3041822B1/en not_active Not-in-force
- 2014-09-02 CN CN201480060895.6A patent/CN105705489B/zh not_active Expired - Fee Related
- 2014-09-02 US US14/915,782 patent/US9872852B2/en active Active
- 2014-09-02 SG SG11201601225RA patent/SG11201601225RA/en unknown
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2016
- 2016-02-29 IL IL24434616A patent/IL244346B/en not_active IP Right Cessation
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017518961A (ja) * | 2014-04-14 | 2017-07-13 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 免疫調節剤として有用な化合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016536333A (ja) | 2016-11-24 |
| ES2642074T3 (es) | 2017-11-15 |
| EP3041822B1 (en) | 2017-08-09 |
| CL2018000150A1 (es) | 2018-05-11 |
| MX2016002544A (es) | 2016-06-17 |
| SG11201601225RA (en) | 2016-03-30 |
| CN105705489A (zh) | 2016-06-22 |
| CA2923184A1 (en) | 2015-03-12 |
| US20160194307A1 (en) | 2016-07-07 |
| PE20160432A1 (es) | 2016-05-11 |
| EP3041822A1 (en) | 2016-07-13 |
| HK1223366A1 (en) | 2017-07-28 |
| AU2014315457B2 (en) | 2018-05-10 |
| CN105705489B (zh) | 2019-04-26 |
| AU2014315457A1 (en) | 2016-04-28 |
| KR102276644B1 (ko) | 2021-07-13 |
| US9872852B2 (en) | 2018-01-23 |
| WO2015034820A1 (en) | 2015-03-12 |
| EA029901B1 (ru) | 2018-05-31 |
| EA201690316A1 (ru) | 2016-07-29 |
| BR112016004194A8 (pt) | 2020-02-11 |
| IL244346B (en) | 2019-10-31 |
| KR20160048946A (ko) | 2016-05-04 |
| IL244346A0 (en) | 2016-04-21 |
| CL2016000508A1 (es) | 2016-11-04 |
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