|
FR2640638B1
(fr)
|
1988-12-20 |
1991-02-15 |
Commissariat Energie Atomique |
Bioreacteur et dispositif pour la culture de cellules animales
|
|
WO1991018088A1
(en)
|
1990-05-23 |
1991-11-28 |
The United States Of America, Represented By The Secretary, United States Department Of Commerce |
Adeno-associated virus (aav)-based eucaryotic vectors
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
GB9027917D0
(en)
|
1990-12-21 |
1991-02-13 |
Ici Plc |
Expression systems
|
|
US5252479A
(en)
|
1991-11-08 |
1993-10-12 |
Research Corporation Technologies, Inc. |
Safe vector for gene therapy
|
|
US5587308A
(en)
|
1992-06-02 |
1996-12-24 |
The United States Of America As Represented By The Department Of Health & Human Services |
Modified adeno-associated virus vector capable of expression from a novel promoter
|
|
US6268213B1
(en)
|
1992-06-03 |
2001-07-31 |
Richard Jude Samulski |
Adeno-associated virus vector and cis-acting regulatory and promoter elements capable of expressing at least one gene and method of using same for gene therapy
|
|
US5693531A
(en)
|
1993-11-24 |
1997-12-02 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vector systems for the generation of adeno-associated virus particles
|
|
EP0755454B1
(en)
|
1994-04-13 |
2008-02-13 |
The Rockefeller University |
Aav-mediated delivery of dna to cells of the nervous system
|
|
US20020159979A1
(en)
|
1994-06-06 |
2002-10-31 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
|
US5658785A
(en)
|
1994-06-06 |
1997-08-19 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
KR100364470B1
(ko)
|
1994-07-15 |
2003-02-05 |
이데미쓰세끼유가가꾸가부시끼가이샤 |
고강성 폴리프로필렌계수지 및 그것을 이용한 블로우성형체
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5652224A
(en)
|
1995-02-24 |
1997-07-29 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for gene therapy for the treatment of defects in lipoprotein metabolism
|
|
US5741657A
(en)
|
1995-03-20 |
1998-04-21 |
The Regents Of The University Of California |
Fluorogenic substrates for β-lactamase and methods of use
|
|
US5756283A
(en)
|
1995-06-05 |
1998-05-26 |
The Trustees Of The University Of Pennsylvania |
Method for improved production of recombinant adeno-associated viruses for gene therapy
|
|
US6281010B1
(en)
|
1995-06-05 |
2001-08-28 |
The Trustees Of The University Of Pennsylvania |
Adenovirus gene therapy vehicle and cell line
|
|
US5741683A
(en)
|
1995-06-07 |
1998-04-21 |
The Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US5688676A
(en)
|
1995-06-07 |
1997-11-18 |
Research Foundation Of State University Of New York |
In vitro packaging of adeno-associated virus DNA
|
|
US6197293B1
(en)
|
1997-03-03 |
2001-03-06 |
Calydon, Inc. |
Adenovirus vectors specific for cells expressing androgen receptor and methods of use thereof
|
|
US6676935B2
(en)
|
1995-06-27 |
2004-01-13 |
Cell Genesys, Inc. |
Tissue specific adenoviral vectors
|
|
JPH11511326A
(ja)
|
1995-08-30 |
1999-10-05 |
ジエンザイム コーポレイション |
アデノウィルスおよびａａｖの精製
|
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
|
US5846528A
(en)
|
1996-01-18 |
1998-12-08 |
Avigen, Inc. |
Treating anemia using recombinant adeno-associated virus virions comprising an EPO DNA sequence
|
|
US5858351A
(en)
|
1996-01-18 |
1999-01-12 |
Avigen, Inc. |
Methods for delivering DNA to muscle cells using recombinant adeno-associated virus vectors
|
|
US5962313A
(en)
|
1996-01-18 |
1999-10-05 |
Avigen, Inc. |
Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme
|
|
US5952221A
(en)
|
1996-03-06 |
1999-09-14 |
Avigen, Inc. |
Adeno-associated virus vectors comprising a first and second nucleic acid sequence
|
|
US7026468B2
(en)
|
1996-07-19 |
2006-04-11 |
Valentis, Inc. |
Process and equipment for plasmid purification
|
|
ATE465267T1
(de)
|
1996-09-06 |
2010-05-15 |
Univ Pennsylvania |
Rekombinante aav zur herstellung eines medikaments für die gentherapie von muskelzellen
|
|
US5866552A
(en)
|
1996-09-06 |
1999-02-02 |
The Trustees Of The University Of Pennsylvania |
Method for expressing a gene in the absence of an immune response
|
|
AU722375B2
(en)
|
1996-09-06 |
2000-08-03 |
Trustees Of The University Of Pennsylvania, The |
Methods using cre-lox for production of recombinant adeno-associated viruses
|
|
EP0931158A1
(en)
|
1996-09-06 |
1999-07-28 |
The Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
|
WO1998010087A1
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
Chimpanzee adenovirus vectors
|
|
US20020037867A1
(en)
|
1999-02-26 |
2002-03-28 |
James M. Wilson |
Method for recombinant adeno-associated virus-directed gene therapy
|
|
EP0932694A2
(en)
|
1996-09-11 |
1999-08-04 |
THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Aav4 vector and uses thereof
|
|
AU732703B2
(en)
|
1996-11-20 |
2001-04-26 |
Crucell Holland B.V. |
An improved method for the production and purification of adenoviral vectors
|
|
US7732129B1
(en)
|
1998-12-01 |
2010-06-08 |
Crucell Holland B.V. |
Method for the production and purification of adenoviral vectors
|
|
CA2270285A1
(en)
|
1996-12-18 |
1998-06-25 |
Targeted Genetics Corporation |
Aav split-packaging genes and cell lines comprising such genes for use in the production of recombinant aav vectors
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6710036B2
(en)
|
1997-07-25 |
2004-03-23 |
Avigen, Inc. |
Induction of immune response to antigens expressed by recombinant adeno-associated virus
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
US6989264B2
(en)
|
1997-09-05 |
2006-01-24 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
AU9319198A
(en)
|
1997-09-19 |
1999-04-05 |
Trustees Of The University Of Pennsylvania, The |
Methods and vector constructs useful for production of recombinant aav
|
|
JP2001517454A
(ja)
|
1997-09-19 |
2001-10-09 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスの産生に有用な方法および細胞株
|
|
CA2304131A1
(en)
|
1997-09-19 |
1999-04-01 |
James M. Wilson |
Method for gene transfer using bcl2 and compositions useful therein
|
|
US6642051B1
(en)
|
1997-10-21 |
2003-11-04 |
Targeted Genetics Corporation |
Amplifiable adeno-associated virus(AAV) packaging cassettes for the production of recombinant AAV vectors
|
|
IT1297074B1
(it)
|
1997-11-21 |
1999-08-03 |
Angeletti P Ist Richerche Bio |
Forme ormone-dipendenti delle proteine rep del virus adeno-associato (aav-2), sequenze di dna codificanti per esse, vettori che le
|
|
JP2001526900A
(ja)
|
1997-12-23 |
2001-12-25 |
イントロヘーネ ベスローテン フェンノートシャップ |
標的細胞の染色体ｄｎａへの外来遺伝子情報の組み込みに有用な、アデノ随伴ウイルスおよびアデノウイルスのキメラ組換えウイルス
|
|
US6410300B1
(en)
|
1998-01-12 |
2002-06-25 |
The University Of North Carolina At Chapel Hill |
Methods and formulations for mediating adeno-associated virus (AAV) attachment and infection and methods for purifying AAV
|
|
WO1999043360A1
(en)
|
1998-02-26 |
1999-09-02 |
The Trustees Of The University Of Pennsylvania |
Stable protection from dystrophic sarcolemmal degeneration and restoration of the sarcoglycan complex
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US6521426B1
(en)
|
1998-04-08 |
2003-02-18 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Preparation of recombinant adenovirus carrying a rep gene of adeno-associated virus
|
|
FR2778413B1
(fr)
|
1998-05-07 |
2000-08-04 |
Immunotech Sa |
Nouveaux reactifs et methode de lyse des erythrocytes
|
|
EP1078096A1
(en)
|
1998-05-11 |
2001-02-28 |
Ariad Gene Therapeutics, Inc. |
Multiviral compositions and uses thereof
|
|
US6436392B1
(en)
|
1998-05-20 |
2002-08-20 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors
|
|
EP1849872A1
(en)
|
1998-05-20 |
2007-10-31 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors and uses thereof
|
|
EP1621626B1
(en)
|
1998-05-27 |
2009-07-08 |
Genzyme Corporation |
AAV Vectors for the manufacture of medicaments for convection enhanced delivery
|
|
US6146874A
(en)
|
1998-05-27 |
2000-11-14 |
University Of Florida |
Method of preparing recombinant adeno-associated virus compositions
|
|
ES2326893T3
(es)
|
1998-05-27 |
2009-10-21 |
Genzyme Corporation |
Vectores aav para la fabricacion de medicamentos para administracion potenciada por conveccion.
|
|
JP2002516345A
(ja)
|
1998-05-27 |
2002-06-04 |
セル ジェネシス インコーポレイテッド |
第ｖｉｉｉ因子活性のアデノ随伴ウイルスベクター媒介性発現
|
|
US6984517B1
(en)
|
1998-05-28 |
2006-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector and uses thereof
|
|
ES2313784T3
(es)
|
1998-05-28 |
2009-03-01 |
The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services |
Vector aav5 y usos del mismo.
|
|
GB2338236B
(en)
|
1998-06-13 |
2003-04-09 |
Aea Technology Plc |
Microbiological cell processing
|
|
US6900049B2
(en)
|
1998-09-10 |
2005-05-31 |
Cell Genesys, Inc. |
Adenovirus vectors containing cell status-specific response elements and methods of use thereof
|
|
WO2000022152A1
(en)
|
1998-10-13 |
2000-04-20 |
Avigen, Inc. |
Compositions and methods for producing recombinant adeno-associated virus
|
|
US6200560B1
(en)
|
1998-10-20 |
2001-03-13 |
Avigen, Inc. |
Adeno-associated virus vectors for expression of factor VIII by target cells
|
|
US6221349B1
(en)
|
1998-10-20 |
2001-04-24 |
Avigen, Inc. |
Adeno-associated vectors for expression of factor VIII by target cells
|
|
EP1124976A1
(en)
|
1998-10-27 |
2001-08-22 |
Crucell Holland B.V. |
Improved aav vector production
|
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
US6689600B1
(en)
|
1998-11-16 |
2004-02-10 |
Introgen Therapeutics, Inc. |
Formulation of adenovirus for gene therapy
|
|
US6759050B1
(en)
|
1998-12-03 |
2004-07-06 |
Avigen, Inc. |
Excipients for use in adeno-associated virus pharmaceutical formulations, and pharmaceutical formulations made therewith
|
|
US6225113B1
(en)
|
1998-12-04 |
2001-05-01 |
Genvec, Inc. |
Use of trans-activation and cis-activation to modulate the persistence of expression of a transgene in an at least E4-deficient adenovirus
|
|
US6387368B1
(en)
|
1999-02-08 |
2002-05-14 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
DE19905501B4
(de)
|
1999-02-10 |
2005-05-19 |
MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie |
Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
|
|
US6509150B1
(en)
|
1999-03-05 |
2003-01-21 |
Universite De Nantes |
Compositions and methods for recombinant Adeno-Associated Virus production
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
JP2002542805A
(ja)
|
1999-04-30 |
2002-12-17 |
ユニバーシティ オブ フロリダ |
アデノ随伴ウイルス送達リボザイム組成物および使用方法
|
|
JP2003501067A
(ja)
|
1999-06-02 |
2003-01-14 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ヘルパーウイルスを要求する組み換えウイルス産生のために有用な組成物及び方法
|
|
CA2382483A1
(en)
|
1999-08-20 |
2001-03-01 |
Johns Hopkins University School Of Medicine |
Methods and compositions for the construction and use of fusion libraries
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
EP1218035A2
(en)
|
1999-09-29 |
2002-07-03 |
The Trustees Of The University Of Pennsylvania |
Rapid peg-modification of viral vectors
|
|
WO2001025465A1
(en)
|
1999-10-07 |
2001-04-12 |
University Of Iowa Research Foundation |
Adeno-associated viruses and uses thereof
|
|
US7241447B1
(en)
|
1999-10-07 |
2007-07-10 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors and uses thereof
|
|
WO2001032711A2
(en)
|
1999-10-21 |
2001-05-10 |
Board Of Trustees Of The University Of Arkansas |
Adeno-associated virus aav rep78 major regulatory protein, mutants thereof and uses thereof
|
|
WO2001036623A2
(en)
|
1999-11-05 |
2001-05-25 |
Avigen, Inc. |
Ecdysone-inducible adeno-associated virus expression vectors
|
|
US6582692B1
(en)
|
1999-11-17 |
2003-06-24 |
Avigen, Inc. |
Recombinant adeno-associated virus virions for the treatment of lysosomal disorders
|
|
EP1240345A2
(en)
|
1999-12-10 |
2002-09-18 |
Ariad Gene Therapeutics, Inc. |
Methods for expression of genes in primates
|
|
EP1228234A2
(en)
|
2000-03-14 |
2002-08-07 |
Neurologix, Inc. |
Production of chimeric capsid vectors
|
|
US7638120B2
(en)
|
2000-03-14 |
2009-12-29 |
Thomas Jefferson University |
High transgene expression of a pseudotyped adeno-associated virus type
|
|
US6468524B1
(en)
|
2000-03-22 |
2002-10-22 |
The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
AAV4 vector and uses thereof
|
|
US6855314B1
(en)
|
2000-03-22 |
2005-02-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector for transducing brain cells and lung cells
|
|
US7048920B2
(en)
|
2000-03-24 |
2006-05-23 |
Cell Genesys, Inc. |
Recombinant oncolytic adenovirus for human melanoma
|
|
GB0009887D0
(en)
|
2000-04-20 |
2000-06-07 |
Btg Int Ltd |
Cytotoxic agents
|
|
US20030013189A1
(en)
|
2000-04-28 |
2003-01-16 |
Wilson James M. |
Compositions and methods useful for non-invasive delivery of therapeutic molecules to the bloodstream
|
|
WO2001083797A2
(en)
|
2000-04-28 |
2001-11-08 |
Avigen, Inc. |
Polynucleotides for use in recombinant adeno-associated virus virion production
|
|
CA2406743A1
(en)
|
2000-04-28 |
2001-11-08 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
|
|
ATE280590T1
(de)
|
2000-05-23 |
2004-11-15 |
Neurologix Inc |
Glutaminsäure decarboxylase (gad) abgabesystem zur behandlung neurodegeneraliver erkrankungen
|
|
AU2001268373A1
(en)
|
2000-06-13 |
2001-12-24 |
The Children's Hospital Of Philadelphia |
Methods for administering recombinant adeno-associated virus virions to humans previously exposed to adeno-associated virus
|
|
WO2002006483A1
(fr)
|
2000-07-18 |
2002-01-24 |
Takeda Chemical Industries, Ltd. |
Nouveau peptide actif sur le plan physiologique et utilisation associee
|
|
US6593123B1
(en)
|
2000-08-07 |
2003-07-15 |
Avigen, Inc. |
Large-scale recombinant adeno-associated virus (rAAV) production and purification
|
|
US6329181B1
(en)
|
2000-08-07 |
2001-12-11 |
Neurologix, Inc. |
Helper functions for recombinant vector production
|
|
WO2002014487A2
(en)
|
2000-08-17 |
2002-02-21 |
Keiya Ozawa |
Adeno-associated virus-mediated delivery of angiogenic factors
|
|
DE10044384A1
(de)
|
2000-09-08 |
2002-04-18 |
Medigene Ag |
Wirtszellen zur Verpackung von rekombinantem Adeno-assoziiertem Virus (rAAV), Verfahren zu ihrer Herstellung und deren Verwendung
|
|
FR2813891B1
(fr)
|
2000-09-14 |
2005-01-14 |
Immunotech Sa |
Reactif multifonctionnel pour erythrocytes mettant en jeu des carbamates et applications
|
|
GB0024550D0
(enExample)
|
2000-10-06 |
2000-11-22 |
Oxford Biomedica Ltd |
|
|
JP2002153278A
(ja)
|
2000-11-22 |
2002-05-28 |
Hisamitsu Pharmaceut Co Inc |
ウイルスベクターの製造に用いられる細胞、その製法およびその細胞を用いたウイルスベクターの製造方法
|
|
WO2002070719A2
(en)
|
2001-01-19 |
2002-09-12 |
Trustees Of The University Of Pennsylvania |
Regulatable gene expression system
|
|
US7588757B2
(en)
|
2001-03-14 |
2009-09-15 |
Genzyme Corporation |
Methods of treating Parkinson's disease using recombinant adeno-associated virus virions
|
|
JP2004532822A
(ja)
|
2001-03-14 |
2004-10-28 |
アビジェン， インコーポレイテッド |
ビリオンの管逆行感染による組換えアデノ随伴ウイルス媒介遺伝子移入
|
|
US6841357B1
(en)
|
2001-03-30 |
2005-01-11 |
Stratagene California |
Method and kits for titering adeno-associated virus vectors
|
|
US7182944B2
(en)
|
2001-04-25 |
2007-02-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Methods of increasing distribution of nucleic acids
|
|
US20030096264A1
(en)
|
2001-06-18 |
2003-05-22 |
Psychiatric Genomics, Inc. |
Multi-parameter high throughput screening assays (MPHTS)
|
|
ES2375557T3
(es)
|
2001-06-22 |
2012-03-02 |
The Trustees Of The University Of Pennsylvania |
Adenovirus recombinantes que comprenden prote�?nas de adenovirus de simios y usos de los mismos.
|
|
US20040136963A1
(en)
|
2001-06-22 |
2004-07-15 |
The Trustees Of The University Of Pennsylvania |
Simian adenovirus vectors and methods of use
|
|
US8241622B2
(en)
|
2001-07-13 |
2012-08-14 |
University Of Iowa Research Foundation |
Adeno-associated virus vectors with intravector heterologous terminal palindromic sequences
|
|
EP1279740A1
(en)
|
2001-07-26 |
2003-01-29 |
Vrije Universiteit Brussel |
Recombinant vector derived from adeno-associated virus for gene therapy
|
|
CA2455499C
(en)
|
2001-08-08 |
2011-06-21 |
The Trustees Of The University Of Pennsylvania |
Method for purification of viral vectors having proteins which bind sialic acid
|
|
US20030092161A1
(en)
|
2001-09-19 |
2003-05-15 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for production of recombinant viruses, and uses therefor
|
|
US6723551B2
(en)
|
2001-11-09 |
2004-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
|
AU2002360355B2
(en)
|
2001-11-09 |
2005-07-07 |
Government Of The United States Of America, Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
|
CA2915124C
(en)
|
2001-11-13 |
2018-08-14 |
The Trustees Of The University Of Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
|
|
KR100987360B1
(ko)
|
2001-11-21 |
2010-10-12 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
원숭이 아데노바이러스 핵산과 아미노산 서열, 이를함유하는 벡터 및 사용방법
|
|
EP1944043A1
(en)
|
2001-11-21 |
2008-07-16 |
The Trustees of the University of Pennsylvania |
Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use
|
|
WO2003049763A1
(en)
|
2001-12-12 |
2003-06-19 |
Fh Faulding & Co Limited |
Composition for the preservation of viruses
|
|
ES2602352T3
(es)
|
2001-12-17 |
2017-02-20 |
The Trustees Of The University Of Pennsylvania |
Secuencias de serotipo 8 de virus adenoasociado (VAA), vectores que las contienen y usos de las mismas
|
|
JP4769417B2
(ja)
|
2001-12-17 |
2011-09-07 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
アデノ随伴ウイルス（ａａｖ）血清型９の配列、それを含むベクターおよびその使用
|
|
EP1463530A4
(en)
|
2001-12-19 |
2006-09-06 |
Lijun Wang |
ADENO-ASSOCIATED VIRUS-RELATED DELIVERY OF GDNF TO SKELETAL MUSCLES
|
|
US8110351B2
(en)
|
2002-01-16 |
2012-02-07 |
Invitrogen Dynal As |
Method for isolating nucleic acids and protein from a single sample
|
|
JP4598398B2
(ja)
|
2002-02-01 |
2010-12-15 |
オックスフォード バイオメディカ （ユーケー） リミテッド |
ウイルスベクター
|
|
GB0208390D0
(en)
|
2002-04-11 |
2002-05-22 |
Univ London |
Adeno-associated virus producer system
|
|
US20030198620A1
(en)
|
2002-04-16 |
2003-10-23 |
Keiya Ozawa |
Method of treating amino acid metabolic disorders using recombinant adeno-associated virus virions
|
|
ES2280694T3
(es)
|
2002-04-29 |
2007-09-16 |
The Trustees Of The University Of Pennsylvania |
Metodo para la extraccion directa y la amplificacion de virus integrados del adn celular de tejidos.
|
|
ATE427990T1
(de)
|
2002-04-30 |
2009-04-15 |
Oncolytics Biotech Inc |
Verbesserte reinigungsmethode fur viren
|
|
DK1496944T3
(da)
|
2002-05-01 |
2008-12-01 |
Univ Florida |
Forbedrede rAAV-ekspressionssystemer til genetisk modificering af specifikke sapsid-proteiner
|
|
WO2003097797A2
(en)
|
2002-05-14 |
2003-11-27 |
Merck & Co., Inc. |
Methods of adenovirus purification
|
|
US7419817B2
(en)
|
2002-05-17 |
2008-09-02 |
The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
|
|
WO2003104413A2
(en)
|
2002-06-05 |
2003-12-18 |
University Of Florida |
Production of pseudotyped recombinant aav virions
|
|
WO2004020605A2
(en)
|
2002-08-29 |
2004-03-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Circular nucleic acid vectors, and methods for making and using the same
|
|
TW200509968A
(en)
|
2002-11-01 |
2005-03-16 |
Elan Pharm Inc |
Prevention and treatment of synucleinopathic disease
|
|
EP1418185A1
(en)
|
2002-11-11 |
2004-05-12 |
Aventis Pharma Deutschland GmbH |
Use of EDG2 receptor in an animal model of heart failure
|
|
US7169612B2
(en)
|
2002-11-11 |
2007-01-30 |
Sanofi-Aventis Deutschland Gmbh |
Use of EDG2 receptor in an animal model of heart failure
|
|
US7510872B2
(en)
|
2003-02-26 |
2009-03-31 |
Nationwide Children's Hospital |
Recombinant adeno-associated virus production
|
|
US20070172460A1
(en)
|
2003-03-19 |
2007-07-26 |
Jurgen Kleinschmidt |
Random peptide library displayed on aav vectors
|
|
WO2004108922A2
(en)
|
2003-04-25 |
2004-12-16 |
The Trustees Of The University Of Pennsylvania |
Use of aav comprising a capsid protein from aav7 or aav8 for the delivery of genes encoding apoprotein a or e genes to the liver
|
|
WO2005017101A2
(en)
|
2003-05-19 |
2005-02-24 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH |
Avian adenoassociated virus (aaav) and uses thereof
|
|
PT1625210E
(pt)
|
2003-05-21 |
2011-03-15 |
Genzyme Corp |
Métodos para produzir preparações de vírions de aav recombinantes substancialmente livres de capsídeos vazios
|
|
EP1486567A1
(en)
|
2003-06-11 |
2004-12-15 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Improved adeno-associated virus (AAV) vector for gene therapy
|
|
JP4888876B2
(ja)
|
2003-06-13 |
2012-02-29 |
田平 武 |
アルツハイマー病の治療のための組換えアデノ随伴ウィルスベクター
|
|
PL3235827T3
(pl)
|
2003-06-19 |
2021-07-05 |
Genzyme Corporation |
Wiriony AAV o zmniejszonej immunoreaktywności i ich zastosowania
|
|
US7291498B2
(en)
|
2003-06-20 |
2007-11-06 |
The Trustees Of The University Of Pennsylvania |
Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
|
|
US7491508B2
(en)
|
2003-06-20 |
2009-02-17 |
The Trustees Of The University Of Pennsylvania |
Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
ES2391975T3
(es)
|
2003-07-25 |
2012-12-03 |
Genvec, Inc. |
Vacunas a base de vector adenovírico
|
|
EP1648914A4
(en)
|
2003-07-31 |
2009-12-16 |
Regulus Therapeutics Inc |
OLIGOMERIC COMPOUNDS AND COMPOSITIONS USEFUL FOR MODULATING SMALL NON-CODING RNA
|
|
US20070073264A1
(en)
|
2003-09-26 |
2007-03-29 |
The Trustees Of The University Of Pennsylvania |
Methods, compositions and apparatus for delivering heterologous molecules to cells
|
|
EP2298926A1
(en)
|
2003-09-30 |
2011-03-23 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
|
|
WO2006078279A2
(en)
|
2004-04-28 |
2006-07-27 |
The Trustees Of The University Of Pennsylvania |
Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations
|
|
WO2005116224A2
(en)
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
|
EP4170024A1
(en)
|
2004-06-01 |
2023-04-26 |
Genzyme Corporation |
Compositions and methods to prevent aav vector aggregation
|
|
CA2581714C
(en)
|
2004-10-05 |
2017-09-12 |
Avigen, Inc. |
Stepped cannula
|
|
US7901921B2
(en)
|
2004-10-22 |
2011-03-08 |
Oncolytics Biotech Inc. |
Viral purification methods
|
|
CN1286981C
(zh)
|
2004-11-30 |
2006-11-29 |
华中科技大学同济医学院附属同济医院 |
表达人类cyp2j2反义基因的重组腺相关病毒及其制备方法
|
|
CN101213305A
(zh)
|
2004-12-09 |
2008-07-02 |
建新公司 |
转基因在哺乳动物中枢神经系统中的可调控型表达
|
|
US8614101B2
(en)
|
2008-05-20 |
2013-12-24 |
Rapid Pathogen Screening, Inc. |
In situ lysis of cells in lateral flow immunoassays
|
|
US7625570B1
(en)
|
2005-03-10 |
2009-12-01 |
The Regents Of The University Of California |
Methods for purifying adeno-associated virus
|
|
WO2006102072A2
(en)
|
2005-03-23 |
2006-09-28 |
The Trustees Of The University Of Pennsylvania |
Use of a pa131 polypeptide in treatment of atherosclerosis
|
|
EP2357010B1
(en)
|
2005-04-07 |
2013-06-12 |
The Trustees of The University of Pennsylvania |
Method of increasing the function of an AAV vector
|
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
|
CN107007842A
(zh)
|
2005-05-02 |
2017-08-04 |
建新公司 |
神经代谢疾病的基因治疗
|
|
HUE043492T2
(hu)
|
2005-08-23 |
2019-08-28 |
Univ Pennsylvania |
Módosított nukleozidokat tartalmazó RNS és eljárások az alkalmazására
|
|
WO2007024841A2
(en)
|
2005-08-23 |
2007-03-01 |
The Regents Of The University Of California |
Reflux resistant cannula and system for chronic delivery of therapeutic agents using convection-enhanced delivery
|
|
EP1857552A1
(en)
|
2006-05-20 |
2007-11-21 |
Cargill Incorporated |
Thermostable xylose isomerase enzyme
|
|
WO2007046703A2
(en)
|
2005-10-20 |
2007-04-26 |
Amsterdam Molecular Therapeutics B.V. |
Improved aav vectors produced in insect cells
|
|
EP1979485A2
(en)
|
2006-01-31 |
2008-10-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
|
EP2007795B1
(en)
|
2006-03-30 |
2016-11-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Aav capsid proteins
|
|
SI2019683T2
(sl)
|
2006-04-25 |
2022-10-28 |
The Regents Of The University Of California |
Dajanje rastnih faktorjev za zdravljenje motenj CŽS
|
|
EP2018421B1
(en)
|
2006-04-28 |
2012-12-19 |
The Trustees of the University of Pennsylvania |
Scalable production method for aav
|
|
US20090317417A1
(en)
|
2006-04-28 |
2009-12-24 |
The Trustees Of The University Of Pennsylvania |
Modified AAV Vectors Having Reduced Capsid Immunogenicity and Use Thereof
|
|
US20090074810A1
(en)
|
2006-04-28 |
2009-03-19 |
The Trustees Of The University Of Pennsylvania |
Modified Adenovirus Hexon Protein and Uses Thereof
|
|
US20080003565A1
(en)
|
2006-05-02 |
2008-01-03 |
Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services |
Viral nucleic acid microarray and method of use
|
|
EP2447279B1
(en)
|
2006-05-25 |
2014-04-09 |
Sangamo BioSciences, Inc. |
Methods and compositions for gene inactivation
|
|
EP2037948B1
(en)
|
2006-05-30 |
2016-04-13 |
Mayo Foundation For Medical Education And Research |
Detecting and treating dementia
|
|
ES2596885T3
(es)
|
2006-06-07 |
2017-01-12 |
Genzyme Corporation |
Terapia génica para esclerosis lateral amiotrófica y otros trastornos de la medula espinal
|
|
ES2535877T3
(es)
|
2006-06-19 |
2015-05-18 |
Asklepios Biopharmaceutical, Inc. |
Genes de Factor VIII y Factor IX modificados y vectores para la terapia génica
|
|
US8512981B2
(en)
|
2006-06-21 |
2013-08-20 |
Amsterdam Molecular Therapeutics B.V. |
Vectors with modified initiation codon for the translation of AAV-Rep78 useful for production of AAV
|
|
SG173337A1
(en)
|
2006-07-21 |
2011-08-29 |
California Inst Of Techn |
Targeted gene delivery for dendritic cell vaccination
|
|
DK2061891T3
(da)
|
2006-08-24 |
2012-07-23 |
Virovek Inc |
Ekspression i insektceller af gener med overlappende åbne læserammer, fremgangsmåder og sammensætninger hertil
|
|
ES2569365T3
(es)
|
2006-11-29 |
2016-05-10 |
Nationwide Children's Hospital |
Inhibición de miostatina para la potenciación de músculo y/o la mejora de la función muscular
|
|
WO2008097503A2
(en)
|
2007-02-02 |
2008-08-14 |
Biogen Idec Ma Inc. |
Use of semaphorin 6a for promoting myelination and oligodendrocyte differentiation
|
|
US20120322861A1
(en)
|
2007-02-23 |
2012-12-20 |
Barry John Byrne |
Compositions and Methods for Treating Diseases
|
|
US9611302B2
(en)
|
2007-04-09 |
2017-04-04 |
University Of Florida Research Foundation, Inc. |
High-transduction-efficiency RAAV vectors, compositions, and methods of use
|
|
HUE030719T2
(en)
|
2007-04-09 |
2017-05-29 |
Univ Florida |
RAAV vector formulations and methods comprising tyrosine-modified capsid proteins for their use
|
|
US9725485B2
(en)
|
2012-05-15 |
2017-08-08 |
University Of Florida Research Foundation, Inc. |
AAV vectors with high transduction efficiency and uses thereof for gene therapy
|
|
WO2008128251A1
(en)
|
2007-04-17 |
2008-10-23 |
The Children's Hospital Of Philadelphia |
Humanized viral vectors and methods of use thereof
|
|
EP2158211B1
(en)
|
2007-05-31 |
2016-08-10 |
Medigene AG |
Mutated structural protein of a parvovirus
|
|
EP2012122A1
(en)
|
2007-07-06 |
2009-01-07 |
Medigene AG |
Mutated parvovirus structural proteins as vaccines
|
|
PT3252161T
(pt)
|
2007-06-06 |
2022-02-01 |
Genzyme Corp |
Terapia genética para doenças do armazenamento lisossomal
|
|
RU2491344C2
(ru)
|
2007-06-29 |
2013-08-27 |
Ф.Хоффманн-Ля Рош Аг |
Промотор
|
|
ES2615180T3
(es)
|
2007-07-14 |
2017-06-05 |
University Of Iowa Research Foundation |
Métodos y composiciones para el tratamiento de enfermedades cerebrales
|
|
KR101597695B1
(ko)
|
2007-07-26 |
2016-02-25 |
유니큐어 아이피 비.브이. |
차등 코돈 바이어스를 갖는 반복 암호 서열을 포함하는 배큘로바이러스 벡터
|
|
US8420372B2
(en)
|
2007-09-04 |
2013-04-16 |
Alexander Bello |
Porcine adeno-associated viruses
|
|
US9115373B2
(en)
|
2007-09-19 |
2015-08-25 |
Uniqure Ip B.V. |
Use of AAV replication machinery for improved protein production
|
|
WO2009051421A2
(en)
|
2007-10-18 |
2009-04-23 |
Lg Electronics Inc. |
Method and system for transmitting and receiving signals
|
|
US8642341B2
(en)
|
2007-11-02 |
2014-02-04 |
Cornell University |
Materials and methods for gene mediated therapy of psychiatric disorders
|
|
CN101883858B
(zh)
|
2007-11-28 |
2015-07-22 |
宾夕法尼亚大学托管会 |
猿猴亚家族E腺病毒SAdV-39、-25.2、-26、-30、-37和-38及其应用
|
|
EP2220217A2
(en)
|
2007-11-28 |
2010-08-25 |
The Trustees of the University of Pennsylvania |
Simian subfamily c adenoviruses sadv-40, -31, and-34 and uses thereof
|
|
CA2706257C
(en)
|
2007-11-28 |
2017-06-06 |
The Trustees Of The University Of Pennsylvania |
Simian subfamily b adenovirus sadv-28, -27, -29, -32, -33 and -35 and uses thereof
|
|
JP5523345B2
(ja)
|
2008-01-18 |
2014-06-18 |
ジェネンテック， インコーポレイテッド |
Ｋ６３結合型ポリユビキチンを標的とする方法と組成物
|
|
WO2009097129A1
(en)
|
2008-01-29 |
2009-08-06 |
Applied Genetic Technologies Corporation |
Recombinant virus production using mammalian cells in suspension
|
|
WO2009104964A1
(en)
|
2008-02-19 |
2009-08-27 |
Amsterdam Molecular Therapeutics B.V. |
Optimisation of expression of parvoviral rep and cap proteins in insect cells
|
|
CN102016011B
(zh)
|
2008-03-04 |
2013-12-11 |
宾夕法尼亚大学托管会 |
猿猴腺病毒sadv-36、-42.1、-42.2和-44及其应用
|
|
US9265843B2
(en)
|
2008-03-27 |
2016-02-23 |
The Ohio State University |
Treatment of metabolic-related disorders using hypothalamic gene transfer of BDNF and compositions therefor
|
|
WO2009134681A2
(en)
|
2008-04-30 |
2009-11-05 |
The Trustees Of The University Of Pennsylvania |
Aav7 viral vectors for targeted delivery of rpe cells
|
|
US8632764B2
(en)
|
2008-04-30 |
2014-01-21 |
University Of North Carolina At Chapel Hill |
Directed evolution and in vivo panning of virus vectors
|
|
MX2010012592A
(es)
|
2008-05-20 |
2011-05-05 |
Eos Neuroscience Inc |
Vectores para la administracion de proteinas sensibles a la luz y metodos de uso de las mismas.
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
EP2297185A1
(en)
|
2008-06-17 |
2011-03-23 |
Amsterdam Molecular Therapeutics (AMT) B.V. |
Parvoviral capsid with incorporated gly-ala repeat region
|
|
US8945885B2
(en)
|
2008-07-03 |
2015-02-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Minicircle DNA vector preparations and methods of making and using the same
|
|
MX2011003229A
(es)
|
2008-09-29 |
2011-09-06 |
Proyecto Biomedicina Cima Sl |
Terapia genica con porfobilinogeno desaminasa.
|
|
DK2350269T3
(en)
|
2008-10-31 |
2015-12-07 |
Univ Pennsylvania |
ABE ADENOVIRUS WITH SADV-46 HEXONCAPSIDE PROTEINS AND APPLICATIONS THEREOF
|
|
WO2011071476A2
(en)
|
2008-11-14 |
2011-06-16 |
Life Technologies Corporation |
Compositions and methods for engineering cells
|
|
US9415121B2
(en)
|
2008-12-19 |
2016-08-16 |
Nationwide Children's Hospital |
Delivery of MECP2 polynucleotide using recombinant AAV9
|
|
ES2634118T3
(es)
|
2009-02-11 |
2017-09-26 |
The University Of North Carolina At Chapel Hill |
Vectores de virus modificados y métodos para fabricar y utilizar los mismos
|
|
MX2011009193A
(es)
|
2009-03-04 |
2011-12-16 |
Deutsches Krebsforsch |
Proteina activadora del ensamblaje (aap) y su uso para la fabricacion de particulas de parvovirus que consisten esencialmente de vp3.
|
|
MX2011010097A
(es)
|
2009-03-27 |
2011-10-19 |
Proyecto Biomedicina Cima Sl |
Metodos y composiciones para el tratamiento de cirrosis y fibrosis hepatica.
|
|
HUE044522T2
(hu)
|
2009-04-30 |
2019-10-28 |
Univ Pennsylvania |
Adeno-asszociált vírus konstrukciókat tartalmazó légúti vezetõ sejtek célzására szolgáló kompozíciók
|
|
AU2010243489A1
(en)
|
2009-05-01 |
2011-12-22 |
Redbiotec Ag |
Recombinant virus-like particles encoded by multi-gene vector
|
|
RS67077B1
(sr)
|
2009-05-02 |
2025-08-29 |
Genzyme Corp |
Genska terapija za neurodegenerativne poremećaje
|
|
US8476418B2
(en)
|
2009-05-28 |
2013-07-02 |
Deutsches Krebsforschungszentrum |
Modified AAV capsid polypeptides
|
|
US8734809B2
(en)
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
|
CA2762203A1
(en)
|
2009-05-29 |
2010-12-02 |
Soumitra Roy |
Simian adenovirus 41 and uses thereof
|
|
CN102803478B
(zh)
|
2009-06-16 |
2016-04-27 |
建新公司 |
用于纯化重组aav载体的改进方法
|
|
CA2767225A1
(en)
|
2009-07-06 |
2011-01-13 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for enhancing production of a biological product
|
|
EP2292781A1
(en)
|
2009-08-17 |
2011-03-09 |
Genethon |
Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions
|
|
WO2011038187A1
(en)
|
2009-09-25 |
2011-03-31 |
The Trustees Of The University Of Pennsylvania |
Controlled adeno-associated virus (aav) diversification and libraries prepared therefrom
|
|
US20120309816A1
(en)
|
2009-11-09 |
2012-12-06 |
Genepod Therapeutics Ab |
Novel viral vector construct for neuron specific optimized continuous DOPA synthesis in vivo
|
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
|
ES2683695T3
(es)
|
2010-01-12 |
2018-09-27 |
The University Of North Carolina At Chapel Hill |
Repeticiones terminales invertidas restrictivas para vectores virales
|
|
EP2528941A4
(en)
|
2010-01-25 |
2013-05-29 |
Univ New York |
FOR TRANSPORT STUDIES AND NEURONAL ADMINISTRATION, MANIPULATED RECOMBINANT DERIVATIVES FROM BOTULINUM NEUROTOXINES
|
|
CA2788682C
(en)
|
2010-02-05 |
2019-03-05 |
The University Of North Carolina At Chapel Hill |
Compositions and methods for enhanced parvovirus transduction
|
|
WO2011112089A2
(en)
|
2010-03-11 |
2011-09-15 |
Amsterdam Molecular Therapeutics (Amt) Ip B.V. |
Mutated rep encoding sequences for use in aav production
|
|
EP2550021A2
(en)
|
2010-03-22 |
2013-01-30 |
Association Institut de Myologie |
Methods of increasing efficiency of vector penetration of target tissue
|
|
SG10201502270TA
(en)
|
2010-03-29 |
2015-05-28 |
Univ Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
US9315825B2
(en)
|
2010-03-29 |
2016-04-19 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
WO2011122950A1
(en)
|
2010-04-01 |
2011-10-06 |
Amsterdam Molecular Therapeutics (Amt) Ip B.V. |
Monomeric duplex aav vectors
|
|
WO2011133874A1
(en)
|
2010-04-23 |
2011-10-27 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
JP2013533847A
(ja)
|
2010-04-23 |
2013-08-29 |
ユニバーシティ オブ マサチューセッツ |
コレステロール関連障害のａａｖベースの治療
|
|
EP3514232A1
(en)
|
2010-04-23 |
2019-07-24 |
University of Massachusetts |
Cns targeting aav vectors and methods of use thereof
|
|
US9839696B2
(en)
|
2010-04-30 |
2017-12-12 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
|
US8927514B2
(en)
|
2010-04-30 |
2015-01-06 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
|
US9309534B2
(en)
|
2010-07-12 |
2016-04-12 |
Universidad Autonoma De Barcelona |
Gene therapy composition for use in diabetes treatment
|
|
US8808684B2
(en)
|
2010-09-10 |
2014-08-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Epidermal growth factor receptor (EGFR) and methods of use in adenoviral-associated virus type 6 (AAV6) transduction
|
|
EP2612909B1
(en)
|
2010-10-05 |
2015-02-25 |
Takara Bio, Inc. |
Method for producing virus vector
|
|
US8663624B2
(en)
|
2010-10-06 |
2014-03-04 |
The Regents Of The University Of California |
Adeno-associated virus virions with variant capsid and methods of use thereof
|
|
WO2012051343A1
(en)
|
2010-10-12 |
2012-04-19 |
The Children's Hospital Of Philadelphia |
Methods and compositions for treating hemophilia b
|
|
CN107828820B
(zh)
*
|
2010-10-27 |
2022-06-07 |
学校法人自治医科大学 |
用于向神经系统细胞导入基因的腺相关病毒粒子
|
|
JP5980790B2
(ja)
|
2010-11-05 |
2016-08-31 |
ブランダイス ユニバーシティＢｒａｎｄｅｉｓ Ｕｎｉｖｅｒｓｉｔｙ |
バイオマーカーとしての、ｉｃｅ切断されたアルファ−シヌクレイン
|
|
EP2637702A4
(en)
|
2010-11-11 |
2014-11-26 |
Univ Miami |
METHODS, COMPOSITIONS, CELLS AND KITS FOR TREATING ISCHEMIC INJURIES
|
|
EP3075860A1
(en)
|
2010-11-23 |
2016-10-05 |
The Trustees of the University of Pennsylvania |
Subfamily e simian adenovirus a1295 and uses thereof
|
|
EP4234571A3
(en)
|
2011-02-10 |
2023-09-27 |
The University of North Carolina at Chapel Hill |
Viral vectors with modified transduction profiles and methods of making and using the same
|
|
JP6224459B2
(ja)
|
2011-02-17 |
2017-11-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組織特異性を改変し、ａａｖ９媒介遺伝子導入を改善するための組成物および方法
|
|
JP6091435B2
(ja)
|
2011-02-22 |
2017-03-08 |
カリフォルニア インスティチュート オブ テクノロジー |
アデノ随伴ウイルス（ａａｖ）ベクターを用いたタンパク質の送達
|
|
GB201103062D0
(en)
|
2011-02-22 |
2011-04-06 |
Isis Innovation |
Method
|
|
US20120220648A1
(en)
*
|
2011-02-24 |
2012-08-30 |
National Taiwan University Hospital |
Method of Treating Aromatic L-Amino Acid Decarboxylase (AADC) Deficiency Using Adeno-Associated Virus (AAV)-AADC Vector
|
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
|
EP2700399B1
(en)
|
2011-04-18 |
2017-05-31 |
National Center of Neurology and Psychiatry |
Drug delivery particles and method for producing same
|
|
WO2012145572A1
(en)
|
2011-04-20 |
2012-10-26 |
The Trustees Of The University Of Pennsylvania |
Regimens and compositions for aav-mediated passive immunization of airborne pathogens
|
|
WO2012145624A2
(en)
|
2011-04-21 |
2012-10-26 |
University Of Massachusetts |
Raav-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
|
|
RS66184B1
(sr)
|
2011-04-22 |
2024-12-31 |
Univ California |
Adeno-povezani virioni virusa sa varijantama kapsida i postupci za njihovu primenu
|
|
WO2012158757A1
(en)
|
2011-05-16 |
2012-11-22 |
The Trustees Of The University Of Pennsylvania |
Proviral plasmids for production of recombinant adeno-associated virus
|
|
WO2012159006A2
(en)
|
2011-05-18 |
2012-11-22 |
University Of Florida Research Foundation, Inc. |
Polypeptides and vectors for targeting her2/neu expressing cells and uses thereof
|
|
US20120295960A1
(en)
|
2011-05-20 |
2012-11-22 |
Oxford Biomedica (Uk) Ltd. |
Treatment regimen for parkinson's disease
|
|
CN103518132B
(zh)
|
2011-06-06 |
2015-11-25 |
拜奥卡蒂斯股份有限公司 |
通过离子型表面活性剂选择性裂解细胞
|
|
ES2623780T3
(es)
|
2011-07-27 |
2017-07-12 |
Genethon |
Sistemas de expresión de baculovirus mejorados
|
|
CA2847604A1
(en)
|
2011-09-08 |
2013-03-14 |
Uniqure Ip B.V. |
Removal of contaminating viruses from aav preparations
|
|
WO2013036889A1
(en)
|
2011-09-09 |
2013-03-14 |
University Of Washington |
Retrograde transport peptide and use of same for delivery to central nervous system
|
|
GB201118636D0
(en)
|
2011-10-28 |
2011-12-07 |
Oxford Biomedica Ltd |
Nucleotide sequence
|
|
JP6165752B2
(ja)
|
2011-10-28 |
2017-07-19 |
ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
アデノ随伴ウイルスの産生のための細胞株
|
|
JP6348064B2
(ja)
|
2011-11-22 |
2018-06-27 |
ザ チルドレンズ ホスピタル オブ フィラデルフィア |
効率の高いトランスジーン送達のためのウイルスベクター
|
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
|
WO2013078316A1
(en)
|
2011-11-23 |
2013-05-30 |
Nationwide Children's Hospital, Inc. |
Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides
|
|
US9611305B2
(en)
|
2012-01-06 |
2017-04-04 |
Mayo Foundation For Medical Education And Research |
Treating cardiovascular or renal diseases
|
|
EP2814513B1
(en)
|
2012-02-14 |
2017-12-20 |
The Regents of The University of California |
Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions
|
|
BR112014020325A2
(pt)
|
2012-02-17 |
2017-08-08 |
Childrens Hospital Philadelphia |
composições de vetor do aav e métodos para a transferência de gene para as células, órgãos e tecidos
|
|
SI2839014T1
(sl)
|
2012-04-18 |
2021-05-31 |
The Children's Hospital Of Philadelphia |
Sestavek in postopki za zelo učinkovit prenos genov z uporabo variant kapside AAV-JA
|
|
US20140162319A2
(en)
|
2012-05-02 |
2014-06-12 |
Sangeetha Hareendran |
Nucleotide sequences, methods, kit and a recombinant cell thereof
|
|
US9163259B2
(en)
|
2012-05-04 |
2015-10-20 |
Novartis Ag |
Viral vectors for the treatment of retinal dystrophy
|
|
CN104395323B
(zh)
|
2012-05-08 |
2017-08-01 |
默沙东公司 |
可透过性糖苷酶抑制剂及其用途
|
|
EP2847337A4
(en)
|
2012-05-09 |
2016-04-27 |
Univ Oregon Health & Science |
ADENO ASSOCIATED VIRUS PLASMIDS AND VECTORS
|
|
TWI775096B
(zh)
|
2012-05-15 |
2022-08-21 |
澳大利亞商艾佛蘭屈澳洲私營有限公司 |
使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
|
|
US10294281B2
(en)
|
2012-05-15 |
2019-05-21 |
University Of Florida Research Foundation, Incorporated |
High-transduction-efficiency rAAV vectors, compositions, and methods of use
|
|
JP6293738B2
(ja)
|
2012-05-18 |
2018-03-14 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
亜科ｅサルアデノウイルスａ１３０２、ａ１３２０、ａ１３３１及びａ１３３７ならびにそれらの使用
|
|
US9540659B2
(en)
|
2012-07-06 |
2017-01-10 |
University Of Iowa Research Foundation |
Modified adeno-associated virus vector compositions
|
|
WO2014007120A1
(ja)
|
2012-07-06 |
2014-01-09 |
タカラバイオ株式会社 |
アデノ随伴ウイルスベクターの産生細胞
|
|
EP3769789A1
(en)
|
2012-08-01 |
2021-01-27 |
Nationwide Children's Hospital |
Intrathecal delivery of recombinant adeno-associated virus 9
|
|
ES2729561T3
(es)
|
2012-08-31 |
2019-11-04 |
Us Health |
Transferencia del gen acuaporina mediada por un virus adenoasociado (aav) para el tratamiento del síndrome de Sjögren
|
|
JP6387350B2
(ja)
|
2012-09-28 |
2018-09-05 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
希突起神経膠細胞を標的とするアデノ随伴ウイルスベクター
|
|
WO2014071042A1
(en)
|
2012-10-31 |
2014-05-08 |
The Trustees Of Columbia University In The City Of New York |
Methods for identifying candidates for the treatment of neurodegenerative diseases
|
|
KR20150105956A
(ko)
|
2012-12-12 |
2015-09-18 |
더 브로드 인스티튜트, 인코퍼레이티드 |
서열 조작 및 치료적 적용을 위한 시스템, 방법 및 조성물의 전달, 유전자 조작 및 최적화
|
|
JP6363958B2
(ja)
|
2012-12-25 |
2018-07-25 |
タカラバイオ株式会社 |
Ａａｖ変異体
|
|
BR122020002822B1
(pt)
|
2013-01-08 |
2023-04-18 |
Genzyme Corporation |
Método para cultivar um vetor de hsv-1 d27.1
|
|
US9066966B2
(en)
|
2013-02-01 |
2015-06-30 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods and pharmaceutical compositions for the treatment of cardiomyopathy due to friedreich ataxia
|
|
US9567376B2
(en)
|
2013-02-08 |
2017-02-14 |
The Trustees Of The University Of Pennsylvania |
Enhanced AAV-mediated gene transfer for retinal therapies
|
|
EP2970946A4
(en)
|
2013-03-13 |
2016-09-07 |
Philadelphia Children Hospital |
ADENOASSOZED VIRUS VECTORS AND METHOD FOR USE THEREOF
|
|
EP2970943A4
(en)
|
2013-03-15 |
2017-04-19 |
The Children's Hospital of Philadelphia |
Vectors comprising stuffer/filler polynucleotide sequences and methods of use
|
|
EP3517612A1
(en)
|
2013-03-15 |
2019-07-31 |
The University of North Carolina At Chapel Hill |
Synthetic adeno-associated virus inverted terminal repeats
|
|
EP2983707B1
(en)
|
2013-04-08 |
2019-06-12 |
University of Iowa Research Foundation |
Chimeric adeno-associated virus/ bocavirus parvovirus vector
|
|
EP2792742A1
(en)
|
2013-04-17 |
2014-10-22 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
Gene-therapy vectors for treating cardiomyopathy
|
|
US10494645B2
(en)
|
2013-04-18 |
2019-12-03 |
Fondazione Telethon |
Effective delivery of large genes by dual AAV vectors
|
|
MX388221B
(es)
|
2013-04-20 |
2025-03-19 |
Res Institute At Nationwide Children´S Hospital |
ADMINISTRACIÓN DE VIRUS ADENO-ASOCIADO RECOMBINANTE DE CONSTRUCCIONES DE POLINUCLÉOTIDOS U7snRNA DIRIGIDA AL EXÓN 2.
|
|
WO2015012924A2
(en)
|
2013-04-29 |
2015-01-29 |
The Trustees Of The University Of Pennsylvania |
Tissue preferential codon modified expression cassettes, vectors containing same, and use thereof
|
|
RU2692251C2
(ru)
|
2013-05-15 |
2019-06-24 |
Риджентс Оф Зэ Юниверсити Оф Миннесота |
Опосредованный аденоассоциированным вирусом перенос генов в центральную нервную систему
|
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
|
ES2897508T3
(es)
|
2013-05-31 |
2022-03-01 |
Univ California |
Variantes de virus adenoasociados y métodos de uso de las mismas
|
|
WO2014201308A1
(en)
|
2013-06-12 |
2014-12-18 |
Washington University |
Endothelial-targeted adenoviral vectors, methods and uses therefor
|
|
WO2014201252A2
(en)
|
2013-06-13 |
2014-12-18 |
Shire Human Genetic Therapies, Inc. |
Messenger rna based viral production
|
|
HUE047996T2
(hu)
|
2013-07-22 |
2020-05-28 |
Childrens Hospital Philadelphia |
AAV variáns és készítmények, eljárások és alkalmazások sejtekbe, szervekbe és szövetekbe történõ géntranszferhez
|
|
MX373332B
(es)
|
2013-07-26 |
2020-05-21 |
Univ Iowa Res Found |
UNA PARTÍCULA rAAV Y UN AGENTE DE INMUNOSUPRESIÓN PARA USARSE EN EL TRATAMIENTO DE ENFERMEDADES.
|
|
ITTO20130669A1
(it)
|
2013-08-05 |
2015-02-06 |
Consiglio Nazionale Ricerche |
Vettore adeno-associato ricombinante muscolo-specifico e suo impiego nel trattamento di patologie muscolari
|
|
US11078464B2
(en)
|
2013-08-30 |
2021-08-03 |
Amgen Inc. |
High titer recombinant AAV vector production in adherent and suspension cells
|
|
EP3044231B1
(en)
|
2013-09-12 |
2020-08-05 |
BioMarin Pharmaceutical Inc. |
Aav vectors comprising a gene encoding factor viii
|
|
US9585971B2
(en)
|
2013-09-13 |
2017-03-07 |
California Institute Of Technology |
Recombinant AAV capsid protein
|
|
US20160354489A1
(en)
|
2013-09-26 |
2016-12-08 |
Universitat Autònome de Barcelona |
Gene therapy compositions for use in the prevention and/or treatment of non-alcoholic fatty liver disease
|
|
JP6985795B2
(ja)
|
2013-09-26 |
2021-12-22 |
ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド |
標的遺伝子治療のための合成コンビナトリアルａａｖカプシドライブラリー
|
|
JP6552511B2
(ja)
|
2013-10-11 |
2019-07-31 |
マサチューセッツ アイ アンド イヤー インファーマリー |
祖先ウイルス配列を予測する方法およびその使用
|
|
CA2927366A1
(en)
|
2013-10-24 |
2015-04-30 |
Uniqure Ip B.V. |
Aav-5 pseudotyped vector for gene therapy for neurological diseases
|
|
WO2015108610A1
(en)
|
2013-11-08 |
2015-07-23 |
The Board Of Trustees Of The University Of Arkansas |
Adeno-associated virus "x" oncogene
|
|
EP3074510B1
(en)
|
2013-11-26 |
2018-08-01 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Adeno-associated virus vectors for treatment of glycogen storage disease
|
|
US10161011B2
(en)
|
2013-11-29 |
2018-12-25 |
Takara Bio Inc. |
Method for quantifying adeno-associated virus
|
|
US9732345B2
(en)
|
2013-12-09 |
2017-08-15 |
Baylor College Of Medicine |
Hippo and dystrophin complex signaling in cardiomyocyte renewal
|
|
SG10201804973TA
(en)
|
2013-12-12 |
2018-07-30 |
Broad Inst Inc |
Compositions and Methods of Use of Crispr-Cas Systems in Nucleotide Repeat Disorders
|
|
GB201322798D0
(en)
|
2013-12-20 |
2014-02-05 |
Oxford Biomedica Ltd |
Production system
|
|
ES2732208T3
(es)
|
2014-01-09 |
2019-11-21 |
Genethon |
Métodos para el diagnóstico o el seguimiento de distrofias musculares
|
|
US20150197809A1
(en)
|
2014-01-13 |
2015-07-16 |
Trustees Of Boston University |
Methods and assays relating to huntingtons disease and parkinson's disease
|
|
GB201401707D0
(en)
|
2014-01-31 |
2014-03-19 |
Sec Dep For Health The |
Adeno-associated viral vectors
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
WO2015124540A1
(en)
|
2014-02-19 |
2015-08-27 |
F. Hoffmann-La Roche Ag |
Blood brain barrier shuttle
|
|
WO2015124546A1
(en)
|
2014-02-19 |
2015-08-27 |
Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii- Cnic |
Aav vectors for the treatment of ischemic and non-ischemic heart disease
|
|
WO2015127128A2
(en)
|
2014-02-19 |
2015-08-27 |
University Of Massachusetts |
Recombinant aavs having useful transcytosis properties
|
|
WO2015126972A1
(en)
|
2014-02-21 |
2015-08-27 |
University Of Florida Research Foundation, Inc. |
Methods and compositions for gene delivery to on bipolar cells
|
|
WO2015127351A1
(en)
|
2014-02-24 |
2015-08-27 |
Celgene Corporation |
Methods of using an activator of cereblon for neural cell expansion and the treatment of central nervous system disorders
|
|
WO2015131076A1
(en)
|
2014-02-27 |
2015-09-03 |
Yale University |
Nlrp6 inflammasome intestinal epithelium mucus secretion
|
|
CA2941640A1
(en)
|
2014-03-04 |
2015-09-11 |
University Of Florida Research Foundation, Inc. |
Improved raav vectors and methods for transduction of photoreceptors and rpe cells
|
|
MX2016011517A
(es)
|
2014-03-07 |
2017-04-13 |
Univ Arizona |
Peptidos de crmp2 no narcoticos que seleccionan como diana canales de sodio para el dolor cronico.
|
|
RS60902B1
(sr)
|
2014-03-09 |
2020-11-30 |
Univ Pennsylvania |
Kompozicije korisne u lečenju nedostatka ornitinske transkarbamilaze (otc)
|
|
PL3117005T3
(pl)
|
2014-03-10 |
2024-11-04 |
Uniqure Ip B.V. |
Dodatkowo ulepszone wektory aav produkowane w komórkach owadzich
|
|
US20170114346A1
(en)
|
2014-04-03 |
2017-04-27 |
Braingene Ab |
Gene expression system and regulation thereof
|
|
EP3556858A3
(en)
|
2014-04-09 |
2020-01-22 |
Editas Medicine, Inc. |
Crispr/cas-related methods and compositions for treating cystic fibrosis
|
|
EP2933335A1
(en)
|
2014-04-18 |
2015-10-21 |
Genethon |
A method of treating peripheral neuropathies and motor neuron diseases
|
|
US10975391B2
(en)
|
2014-04-25 |
2021-04-13 |
University Of Massachusetts |
Recombinant AAV vectors useful for reducing immunity against transgene products
|
|
WO2015164778A1
(en)
|
2014-04-25 |
2015-10-29 |
The Trustees Of The University Of Pennysylvania |
Ldlr variants and their use in compositions for reducing cholesterol levels
|
|
WO2015173436A1
(en)
|
2014-05-16 |
2015-11-19 |
Vrije Universiteit Brussel |
Genetic correction of myotonic dystrophy type 1
|
|
WO2015191508A1
(en)
|
2014-06-09 |
2015-12-17 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
EP3154560B1
(en)
|
2014-06-13 |
2019-03-13 |
University of Pittsburgh - Of the Commonwealth System of Higher Education |
Methods and materials for increasing viral vector infectivity
|
|
WO2015196179A1
(en)
|
2014-06-20 |
2015-12-23 |
University Of Florida Research Foundation, Inc. |
Methods of packaging multiple adeno-associated virus vectors
|
|
EP2960336A1
(en)
|
2014-06-27 |
2015-12-30 |
Genethon |
Efficient systemic treatment of dystrophic muscle pathologies
|
|
US10526583B2
(en)
|
2014-07-02 |
2020-01-07 |
University Of Florida Research Foundation, Incorporated |
Compositions and methods for purifying recombinant adeno-associated virus
|
|
WO2016006658A1
(ja)
|
2014-07-10 |
2016-01-14 |
タカラバイオ株式会社 |
非エンベロープウイルス粒子の製造方法
|
|
US9616090B2
(en)
|
2014-07-30 |
2017-04-11 |
Sangamo Biosciences, Inc. |
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
|
|
WO2016019364A1
(en)
|
2014-08-01 |
2016-02-04 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for self-regulated inducible gene expression
|
|
US10711270B2
(en)
|
2014-10-03 |
2020-07-14 |
University Of Massachusetts |
High efficiency library-identified AAV vectors
|
|
US10370432B2
(en)
|
2014-10-03 |
2019-08-06 |
University Of Massachusetts |
Heterologous targeting peptide grafted AAVS
|
|
WO2016057975A2
(en)
|
2014-10-10 |
2016-04-14 |
Research Institute At Nationwide Children's Hospital |
Guided injections for aav gene transfer to muscle
|
|
RU2020140209A
(ru)
|
2014-10-21 |
2021-01-25 |
Юниверсити Оф Массачусетс |
Варианты рекомбинантных aav и их применения
|
|
CN107106689A
(zh)
|
2014-11-05 |
2017-08-29 |
沃雅戈治疗公司 |
用于治疗帕金森病的aadc多核苷酸
|
|
WO2016073739A1
(en)
|
2014-11-05 |
2016-05-12 |
Research Institute At Nationwide Children's Hospital |
Methods and materials for producing recombinant viruses in eukaryotic microalgae
|
|
PT3221349T
(pt)
|
2014-11-19 |
2021-01-21 |
Axon Neuroscience Se |
Anticorpos tau humanizados na doença de alzheimer
|
|
RU2727015C2
(ru)
|
2014-11-21 |
2020-07-17 |
Дзе Юниверсити Оф Норт Каролина Эт Чепел Хилл |
Векторы aav, нацеленные на центральную нервную систему
|
|
US10900053B2
(en)
|
2014-11-21 |
2021-01-26 |
University Of Florida Research Foundation, Incorporated |
Genome-modified recombinant adeno-associated virus vectors
|
|
HK1244849B
(en)
|
2014-11-28 |
2020-04-09 |
Uniqure Ip B.V. |
Dna impurities in a composition comprising a parvoviral virion
|
|
US11697825B2
(en)
|
2014-12-12 |
2023-07-11 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scAAV
|
|
WO2016115382A1
(en)
|
2015-01-14 |
2016-07-21 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeted gene transfer
|
|
EP3250279B1
(en)
|
2015-01-30 |
2020-08-19 |
The Regents of the University of California |
Spinal subpial gene delivery system
|
|
US20180030096A1
(en)
|
2015-02-03 |
2018-02-01 |
University Of Florida Research Foundation, Inc. |
Recombinant aav1, aav5, and aav6 capsid mutants and uses thereof
|
|
AU2016219398A1
(en)
|
2015-02-10 |
2017-09-28 |
Genzyme Corporation |
Enhanced delivery of viral particles to the striatum and cortex
|
|
US20180245073A1
(en)
|
2015-02-23 |
2018-08-30 |
Voyager Therapeutics, Inc. |
Regulatable expression using adeno-associated virus (aav)
|
|
AU2016229000B2
(en)
|
2015-03-10 |
2021-11-04 |
The Trustees Of Columbia University In The City Of New York |
Recombinant Glut1 adeno-associated viral vector constructs and related methods for restoring Glut1 expression
|
|
CN107614008A
(zh)
|
2015-03-20 |
2018-01-19 |
蓝鸟生物公司 |
载体制剂
|
|
EP3277819B1
(en)
|
2015-03-24 |
2021-03-03 |
The Regents of The University of California |
Adeno-associated virus variants and methods of use thereof
|
|
WO2016161388A1
(en)
|
2015-04-03 |
2016-10-06 |
University Of Massachusetts |
Fully stabilized asymmetric sirna
|
|
US10081659B2
(en)
|
2015-04-06 |
2018-09-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Adeno-associated vectors for enhanced transduction and reduced immunogenicity
|
|
TWI707951B
(zh)
|
2015-04-08 |
2020-10-21 |
美商健臻公司 |
過大腺相關載體之製造
|
|
US10058624B2
(en)
|
2015-04-16 |
2018-08-28 |
Emory University |
Recombinant promoters and vectors for protein expression in liver and use thereof
|
|
US11020443B2
(en)
|
2015-04-23 |
2021-06-01 |
University Of Massachusetts |
Modulation of AAV vector transgene expression
|
|
WO2016172008A1
(en)
|
2015-04-24 |
2016-10-27 |
University Of Massachusetts |
Modified aav constructions and uses thereof
|
|
WO2016179038A1
(en)
|
2015-05-01 |
2016-11-10 |
Spark Therapeutics, Inc. |
ADENO-ASSOCIATED VIRUS-MEDIATED CRISPR-Cas9 TREATMENT OF OCULAR DISEASE
|
|
EP3291765A4
(en)
|
2015-05-07 |
2019-01-23 |
Massachusetts Eye & Ear Infirmary |
METHOD FOR THE DELIVERY OF AN ACTIVE SUBSTANCE TO THE EYE
|
|
WO2016183123A1
(en)
|
2015-05-11 |
2016-11-17 |
Alcyone Lifesciences, Inc. |
Drug delivery systems and methods
|
|
CA2985786A1
(en)
|
2015-05-12 |
2016-11-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Aav isolate and fusion protein comprising nerve growth factor signal peptide and parathyroid hormone
|
|
US20170067028A1
(en)
|
2015-05-15 |
2017-03-09 |
Douglas J. Ballon |
Radiolabeling of adeno associated virus
|
|
WO2016191418A1
(en)
|
2015-05-26 |
2016-12-01 |
Salk Institute For Biological Studies |
Motor neuron-specific expression vectors
|
|
SG10202012832VA
(en)
|
2015-05-28 |
2021-01-28 |
Univ Cornell |
Adeno-associated virus mediated delivery of c1ei as a therapy for angioedema
|
|
JP7011467B2
(ja)
|
2015-05-29 |
2022-02-10 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ミスフォールドタンパク質の分解のための組成物及び方法
|
|
WO2016196507A1
(en)
|
2015-05-29 |
2016-12-08 |
University Of Iowa Research Foundation |
Methods of delivery of transgenes for treating brain diseases
|
|
PT3313991T
(pt)
|
2015-06-23 |
2024-09-27 |
Childrens Hospital Philadelphia |
Fator ix modificado e composições, métodos e utilizações para transferência de genes para células, órgãos e tecidos
|
|
US11266748B2
(en)
|
2015-07-02 |
2022-03-08 |
University Of Florida Research Foundation, Incorporated |
Recombinant adeno-associated virus vectors to target medullary thyroid carcinoma
|
|
ES2895652T3
(es)
|
2015-07-07 |
2022-02-22 |
Inst Nat Sante Rech Med |
Métodos y composiciones farmacéuticas para expresar un polinucleótido de interés en el sistema nervioso periférico de un sujeto
|
|
US20170007669A1
(en)
|
2015-07-07 |
2017-01-12 |
Mayo Foundation For Medical Education And Research |
Peptide-mediated delivery of active agents across the blood-brain barrier
|
|
US20180216133A1
(en)
|
2015-07-17 |
2018-08-02 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for achieving high levels of transduction in human liver cells
|
|
US20180214576A1
(en)
|
2015-07-28 |
2018-08-02 |
University Of Massachusetts |
Transgenic expression of dnasei in vivo delivered by an adeno-associated virus vector
|
|
LT3872085T
(lt)
|
2015-07-30 |
2023-05-10 |
Massachusetts Eye & Ear Infirmary |
Viruso prototipo sekos ir jų panaudojimas
|
|
WO2017023724A1
(en)
|
2015-07-31 |
2017-02-09 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
EP3332012A4
(en)
|
2015-08-06 |
2019-01-16 |
The Trustees of The University of Pennsylvania |
GLP-1 AND USE THEREOF IN COMPOSITIONS FOR THE TREATMENT OF METABOLISM DISEASES
|
|
MA42934A
(fr)
|
2015-09-24 |
2018-08-01 |
Biomarin Pharm Inc |
Vecteurs de facteur viii à virus adéno-associé, particules virales associées et formulations thérapeutiques comprenant ceux-ci
|
|
EP3831842A1
(en)
|
2015-09-28 |
2021-06-09 |
The University of North Carolina at Chapel Hill |
Methods and compositions for antibody-evading virus vectors
|
|
IL258538B2
(en)
|
2015-10-09 |
2023-04-01 |
Genzyme Corp |
Early isolation after the infection of cells (epic) for the production of biological material
|
|
US10123969B2
(en)
|
2015-10-15 |
2018-11-13 |
Wisconsin Alumni Research Foundation |
Osmotic enhancement of drug/therapeutic delivery to the brain following infusion or injection into the cerebrospinal fluid
|
|
US11426469B2
(en)
|
2015-10-22 |
2022-08-30 |
University Of Massachusetts |
Prostate-targeting adeno-associated virus serotype vectors
|
|
US12188037B2
(en)
|
2015-10-22 |
2025-01-07 |
University Of Florida Research Foundation, Incorporated |
Synthetic combinatorial AAV3 capsid library
|
|
CA3002982A1
(en)
|
2015-10-22 |
2017-04-27 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance in neurodegenerative disease
|
|
WO2017070678A1
(en)
|
2015-10-23 |
2017-04-27 |
University Of Iowa Research Foundation |
Methods for treating neurodegenerative diseases using gene therapy to delay disease onset and progression while providing cognitive protection
|
|
WO2017075119A1
(en)
|
2015-10-28 |
2017-05-04 |
The Trustees Of The Univeresity Of Pennsylvania |
Intrathecal administration of adeno-associated-viral vectors for gene therapy
|
|
EP3368054A4
(en)
|
2015-10-28 |
2019-07-03 |
Voyager Therapeutics, Inc. |
REGULATORY EXPRESSION USING THE ADENO-ASSOCIATED VIRUS (AAV)
|
|
EP3371217B1
(en)
|
2015-11-08 |
2025-06-11 |
F. Hoffmann-La Roche AG |
Methods of screening for multispecific antibodies
|
|
US10633662B2
(en)
|
2015-11-10 |
2020-04-28 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for modulating AAV infection
|
|
KR20180091863A
(ko)
|
2015-12-01 |
2018-08-16 |
스파크 테라퓨틱스, 인코포레이티드 |
임상적 사용에 적합한 무혈청 현탁 세포 배양 시스템에서 재조합 아데노-관련 바이러스(aav) 벡터를 생성하기 위한 확장가능한 방법
|
|
WO2017095753A1
(en)
|
2015-12-01 |
2017-06-08 |
Invivo Therapeutics Corporation |
Compositions and methods for preparing an injectable medium for administration into the central nervous system
|
|
WO2017096164A1
(en)
|
2015-12-02 |
2017-06-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
Novel recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism
|
|
US10406244B2
(en)
|
2015-12-02 |
2019-09-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
AAV vectors with expanded packaging capacity
|
|
EP3383896A1
(en)
|
2015-12-03 |
2018-10-10 |
Genethon |
Compositions and methods for improving viral vector efficiency
|
|
AU2016366549B2
(en)
|
2015-12-11 |
2022-11-10 |
California Institute Of Technology |
Targeting peptides for directing adeno-associated viruses (AAVs)
|
|
WO2017160360A2
(en)
|
2015-12-11 |
2017-09-21 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav9
|
|
ES2934848T3
(es)
|
2015-12-11 |
2023-02-27 |
Univ Pennsylvania |
Método de purificación escalable para AAV8
|
|
WO2017100704A1
(en)
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aavrh10
|
|
WO2017100674A1
(en)
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav1
|
|
JP7406783B2
(ja)
|
2015-12-14 |
2023-12-28 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
パルボウイルスベクターの高められた送達のための改変キャプシドタンパク質
|
|
US11208630B2
(en)
|
2015-12-24 |
2021-12-28 |
University Of Florida Research Foundation, Incorporated |
AAV production using suspension adapted cells
|
|
RU2771490C2
(ru)
|
2016-01-13 |
2022-05-05 |
Мериал, Инк. |
Рекомбинантные aav векторы, экспрессирующие остеопротективные гены, включая has2 и лубрицин, пригодные при лечении остеоартрита и сходных заболеваний суставов у млекопитающих
|
|
WO2017122789A1
(ja)
|
2016-01-15 |
2017-07-20 |
学校法人自治医科大学 |
てんかん治療のためのアデノ随伴ウイルスビリオン
|
|
US11826433B2
(en)
|
2016-02-02 |
2023-11-28 |
University Of Massachusetts |
Method to enhance the efficiency of systemic AAV gene delivery to the central nervous system
|
|
IL300254B2
(en)
|
2016-02-05 |
2025-06-01 |
Univ Emory |
Administration of single stranded or self-complementary adeno-associated virus 9 by injection into the cerebrospinal fluid to target gene therapy to the central nervous system
|
|
US11702672B2
(en)
|
2016-02-08 |
2023-07-18 |
University Of Iowa Research Foundation |
Methods to produce chimeric adeno-associated virus/bocavirus parvovirus
|
|
AU2017219865B2
(en)
|
2016-02-16 |
2023-04-13 |
The Board Of Trustees Of The Leland Stanford Junior University |
Novel recombinant adeno-associated virus capsids resistant to pre-existing human neutralizing antibodies
|
|
US20190071681A1
(en)
|
2016-02-26 |
2019-03-07 |
University Of Florida Research Foundation, Incorporated |
Aav heparin mutants that display significantly improved eye and brain transduction
|
|
CA3016314A1
(en)
|
2016-03-02 |
2017-09-08 |
Julianne REIDERS |
Therapy for frontotemporal dementia
|
|
PT3423110T
(pt)
|
2016-03-03 |
2021-11-09 |
Univ Massachusetts |
Adn em dúplex linear de extremidades fechadas para transferência génica não viral
|
|
EP3426787A1
(en)
|
2016-03-07 |
2019-01-16 |
University of Iowa Research Foundation |
Aav-mediated expression using a synthetic promoter and enhancer
|
|
AU2017237912B2
(en)
|
2016-03-23 |
2022-03-10 |
The Regents Of The University Of California |
Methods of treating mitochondrial disorders
|
|
WO2017165859A1
(en)
|
2016-03-24 |
2017-09-28 |
Research Institute At Nationwide Children's Hospital |
Modified viral capsid proteins
|
|
WO2017172772A1
(en)
|
2016-03-28 |
2017-10-05 |
Dimension Therapeutics |
Methods of heat inactivation of adenovirus
|
|
CA3039910A1
(en)
|
2016-03-28 |
2017-10-05 |
The Regents Of The University Of California |
Anti-ryk antibodies and methods of using the same
|
|
MX2018011928A
(es)
|
2016-03-30 |
2019-03-28 |
Spark Therapeutics Inc |
Linea celular para produccion de proteina recombinante y/o vector viral.
|
|
PH12018502104B1
(en)
|
2016-03-31 |
2024-03-27 |
Spark Therapeutics Inc |
Column-based fully scalable raav manufacturing process
|
|
CN109661470A
(zh)
|
2016-04-15 |
2019-04-19 |
宾夕法尼亚州大学信托人 |
新型aav8突变衣壳和含有其的组合物
|
|
JP6975980B2
(ja)
|
2016-04-16 |
2021-12-01 |
ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド |
バキュロウイルス系で産生される組換えアデノ随伴ウイルスの生物学的力価を増強する方法
|
|
KR20180134846A
(ko)
|
2016-04-21 |
2018-12-19 |
바이로베크 인코포레이티드 |
곤충 세포에서의 aav 생산, 및 이를 위한 방법 및 조성물
|
|
EP3235516B1
(en)
|
2016-04-22 |
2019-06-26 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin |
Regulatable adeno-associated virus (aav) vector
|
|
EP3449250B1
(en)
|
2016-04-28 |
2020-11-04 |
Indiana University Research & Technology Corporation |
Methods and compositions for resolving components of a virus preparation
|
|
AU2017261249B2
(en)
|
2016-05-03 |
2021-05-06 |
Children's Medical Research Institute |
Adeno-associated virus polynucleotides, polypeptides and virions
|
|
WO2017192750A1
(en)
|
2016-05-04 |
2017-11-09 |
Oregon Health & Science University |
Recombinant adeno-associated viral vectors
|
|
US10898585B2
(en)
|
2017-04-14 |
2021-01-26 |
Ptc Therapeutics .Inc. |
Gene therapy for AADC deficiency
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
MX2020012077A
(es)
|
2018-05-15 |
2021-03-09 |
Voyager Therapeutics Inc |
Composiciones y metodos para el tratamiento de la enfermedad de parkinson.
|