JP2017529395A5 - - Google Patents
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- Publication number
- JP2017529395A5 JP2017529395A5 JP2017534525A JP2017534525A JP2017529395A5 JP 2017529395 A5 JP2017529395 A5 JP 2017529395A5 JP 2017534525 A JP2017534525 A JP 2017534525A JP 2017534525 A JP2017534525 A JP 2017534525A JP 2017529395 A5 JP2017529395 A5 JP 2017529395A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seq
- myoc
- aav2
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051299P | 2014-09-16 | 2014-09-16 | |
| US62/051,299 | 2014-09-16 | ||
| PCT/US2015/050515 WO2016044478A1 (en) | 2014-09-16 | 2015-09-16 | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036344A Division JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529395A JP2017529395A (ja) | 2017-10-05 |
| JP2017529395A5 true JP2017529395A5 (enExample) | 2018-10-25 |
| JP6673923B2 JP6673923B2 (ja) | 2020-03-25 |
Family
ID=58640637
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534525A Active JP6673923B2 (ja) | 2014-09-16 | 2015-09-16 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
| JP2020036344A Active JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036344A Active JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10821193B2 (enExample) |
| EP (1) | EP3194601B1 (enExample) |
| JP (2) | JP6673923B2 (enExample) |
| KR (3) | KR20260019013A (enExample) |
| CN (2) | CN116585492A (enExample) |
| AU (2) | AU2015317756B2 (enExample) |
| BR (1) | BR112017005235B1 (enExample) |
| CA (2) | CA3280614A1 (enExample) |
| IL (1) | IL251178B (enExample) |
| MX (2) | MX2017003426A (enExample) |
| RU (2) | RU2718047C2 (enExample) |
| SG (3) | SG10201913430VA (enExample) |
| ZA (1) | ZA201701881B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3280614A1 (en) | 2014-09-16 | 2026-03-02 | Genzyme Corporation | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
| JP7287611B2 (ja) * | 2018-02-07 | 2023-06-06 | 学校法人日本医科大学 | 改良型アデノ随伴ウイルスベクター |
| WO2019165241A1 (en) * | 2018-02-22 | 2019-08-29 | University Of South Florida | Grp94 inhibitors to treat steroid-induced ocular hypertensions and glaucomas |
| US20220047618A1 (en) | 2019-02-28 | 2022-02-17 | Regeneron Pharmaceuticals, Inc. | Adeno-associated virus vectors for the delivery of therapeutics |
| EP4255457A4 (en) * | 2020-12-03 | 2025-05-21 | University of Massachusetts | DEVELOPMENT OF NEW GENE THERAPEUTIC AGENTS FOR FIBRODYSPLASIA OSSIFICANS PROGRESSIVA |
| CN113032010B (zh) * | 2021-03-12 | 2022-09-20 | 歌尔科技有限公司 | 命令的传输控制方法、终端及计算机可读存储介质 |
| EP4363587A4 (en) * | 2021-06-28 | 2025-08-06 | Alnylam Pharmaceuticals Inc | COMPOSITIONS AND METHODS FOR SILENCING MYOC EXPRESSION |
| US12582104B2 (en) | 2021-12-08 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Mutant myocilin disease model and uses thereof |
| EP4447806A4 (en) * | 2021-12-16 | 2025-10-01 | Peter Koulen | Machine learning-based framework using electroretinography to detect early-stage glaucoma |
| CN117343152B (zh) * | 2023-04-18 | 2024-06-04 | 上海本导基因技术有限公司 | 一种用于治疗青光眼疾病的慢病毒样颗粒 |
| CN118546217B (zh) * | 2024-07-25 | 2024-10-29 | 广州译码基因科技有限公司 | 靶向小梁网、角膜缘及rpe的aav衣壳蛋白及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005514917A (ja) | 2001-10-03 | 2005-05-26 | インサイト・ゲノミックス・インコーポレイテッド | 分泌タンパク質 |
| GB0403600D0 (en) * | 2004-02-18 | 2004-03-24 | Trinity College Dublin | Methods and reagents for treating disease |
| WO2005117938A2 (en) * | 2004-04-13 | 2005-12-15 | Regents Of The University Of Minnesota | Methods of treating ocular conditions |
| WO2008075796A1 (ja) * | 2006-12-21 | 2008-06-26 | Kyowa Hakko Kirin Co., Ltd. | 血球回復促進剤 |
| BRPI0817937A2 (pt) * | 2007-10-01 | 2015-04-07 | Alcon Res Ltd | Entrega mediada por aav autocomplementar de moléculas de rna de interferência para tratar ou prevenir distúrbios oculares |
| GB201106395D0 (en) * | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| CN107012171B (zh) * | 2011-04-22 | 2021-07-13 | 加利福尼亚大学董事会 | 具有变异衣壳的腺相关病毒病毒体及其使用方法 |
| EP2554662A1 (en) * | 2011-08-05 | 2013-02-06 | M Maria Pia Cosma | Methods of treatment of retinal degeneration diseases |
| HK1211037A1 (en) * | 2012-02-11 | 2016-05-13 | 霍夫曼-拉罗奇有限公司 | R-spondin translocations and methods using the same |
| EP3470523A1 (en) * | 2012-05-09 | 2019-04-17 | Oregon Health & Science University | Adeno associated virus plasmids and vectors |
| CA3280614A1 (en) | 2014-09-16 | 2026-03-02 | Genzyme Corporation | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
-
2015
- 2015-09-16 CA CA3280614A patent/CA3280614A1/en active Pending
- 2015-09-16 KR KR1020267001828A patent/KR20260019013A/ko active Pending
- 2015-09-16 BR BR112017005235-0A patent/BR112017005235B1/pt active IP Right Grant
- 2015-09-16 IL IL251178A patent/IL251178B/en unknown
- 2015-09-16 JP JP2017534525A patent/JP6673923B2/ja active Active
- 2015-09-16 SG SG10201913430VA patent/SG10201913430VA/en unknown
- 2015-09-16 CA CA2961523A patent/CA2961523C/en active Active
- 2015-09-16 RU RU2017112972A patent/RU2718047C2/ru active
- 2015-09-16 CN CN202211533202.3A patent/CN116585492A/zh active Pending
- 2015-09-16 KR KR1020177010012A patent/KR102612871B1/ko active Active
- 2015-09-16 SG SG10201902285SA patent/SG10201902285SA/en unknown
- 2015-09-16 EP EP15772133.3A patent/EP3194601B1/en active Active
- 2015-09-16 US US15/511,595 patent/US10821193B2/en active Active
- 2015-09-16 RU RU2020111038A patent/RU2746991C2/ru active
- 2015-09-16 AU AU2015317756A patent/AU2015317756B2/en active Active
- 2015-09-16 SG SG11201702055PA patent/SG11201702055PA/en unknown
- 2015-09-16 CN CN201580061882.5A patent/CN107001436B/zh active Active
- 2015-09-16 MX MX2017003426A patent/MX2017003426A/es unknown
- 2015-09-16 KR KR1020237042363A patent/KR102916865B1/ko active Active
-
2017
- 2017-03-15 MX MX2023005998A patent/MX2023005998A/es unknown
- 2017-03-16 ZA ZA2017/01881A patent/ZA201701881B/en unknown
-
2020
- 2020-03-04 JP JP2020036344A patent/JP7097398B2/ja active Active
-
2022
- 2022-04-12 AU AU2022202413A patent/AU2022202413A1/en not_active Abandoned
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