JP2017529395A5 - - Google Patents
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- Publication number
- JP2017529395A5 JP2017529395A5 JP2017534525A JP2017534525A JP2017529395A5 JP 2017529395 A5 JP2017529395 A5 JP 2017529395A5 JP 2017534525 A JP2017534525 A JP 2017534525A JP 2017534525 A JP2017534525 A JP 2017534525A JP 2017529395 A5 JP2017529395 A5 JP 2017529395A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seq
- myoc
- aav2
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051299P | 2014-09-16 | 2014-09-16 | |
| US62/051,299 | 2014-09-16 | ||
| PCT/US2015/050515 WO2016044478A1 (en) | 2014-09-16 | 2015-09-16 | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036344A Division JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529395A JP2017529395A (ja) | 2017-10-05 |
| JP2017529395A5 true JP2017529395A5 (enExample) | 2018-10-25 |
| JP6673923B2 JP6673923B2 (ja) | 2020-03-25 |
Family
ID=58640637
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534525A Active JP6673923B2 (ja) | 2014-09-16 | 2015-09-16 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
| JP2020036344A Active JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036344A Active JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10821193B2 (enExample) |
| EP (1) | EP3194601B1 (enExample) |
| JP (2) | JP6673923B2 (enExample) |
| KR (3) | KR20260019013A (enExample) |
| CN (2) | CN116585492A (enExample) |
| AU (2) | AU2015317756B2 (enExample) |
| BR (1) | BR112017005235B1 (enExample) |
| CA (1) | CA2961523C (enExample) |
| IL (1) | IL251178B (enExample) |
| MX (2) | MX2017003426A (enExample) |
| RU (2) | RU2718047C2 (enExample) |
| SG (3) | SG10201913430VA (enExample) |
| ZA (1) | ZA201701881B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL251178B (en) | 2014-09-16 | 2022-07-01 | Genzyme Corp | Adeno-associated viral vector for the treatment of glaucoma myocilin (myoc) |
| US11845952B2 (en) * | 2018-02-07 | 2023-12-19 | Nippon Medical School Foundation | Adeno-associated virus vector |
| US20210030719A1 (en) * | 2018-02-22 | 2021-02-04 | University Of South Florida | Grp94 inhibitors to treat steroid-induced ocular hypertensions and glaucomas |
| WO2020176747A1 (en) | 2019-02-28 | 2020-09-03 | Regeneron Pharmaceuticals, Inc. | Adeno-associated virus vectors for the delivery of therapeutics |
| US11674154B2 (en) * | 2020-12-03 | 2023-06-13 | University Of Massachusetts | Gene therapeutics for fibrodysplasia ossificans progressiva |
| CN113032010B (zh) * | 2021-03-12 | 2022-09-20 | 歌尔科技有限公司 | 命令的传输控制方法、终端及计算机可读存储介质 |
| WO2023278406A1 (en) * | 2021-06-28 | 2023-01-05 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for silencing myoc expression |
| KR20240117571A (ko) * | 2021-12-08 | 2024-08-01 | 리제너론 파마슈티칼스 인코포레이티드 | 돌연변이 마이오실린 질환 모델 및 이의 용도 |
| WO2023114446A2 (en) * | 2021-12-16 | 2023-06-22 | Peter Koulen | A machine learning-based framework using electroretinography for detecting early-stage glaucoma |
| CN117343152B (zh) * | 2023-04-18 | 2024-06-04 | 上海本导基因技术有限公司 | 一种用于治疗青光眼疾病的慢病毒样颗粒 |
| CN118546217B (zh) * | 2024-07-25 | 2024-10-29 | 广州译码基因科技有限公司 | 靶向小梁网、角膜缘及rpe的aav衣壳蛋白及其应用 |
| CN121449764A (zh) * | 2026-01-07 | 2026-02-03 | 山东伯桢生物科技有限公司 | 抑制Wnt信号通路的融合蛋白及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2462795A1 (en) | 2001-10-03 | 2003-04-10 | Incyte Genomics, Inc. | Secreted proteins |
| GB0403600D0 (en) * | 2004-02-18 | 2004-03-24 | Trinity College Dublin | Methods and reagents for treating disease |
| WO2005117938A2 (en) * | 2004-04-13 | 2005-12-15 | Regents Of The University Of Minnesota | Methods of treating ocular conditions |
| WO2008075796A1 (ja) * | 2006-12-21 | 2008-06-26 | Kyowa Hakko Kirin Co., Ltd. | 血球回復促進剤 |
| KR20100061792A (ko) * | 2007-10-01 | 2010-06-09 | 알콘 리서치, 리미티드 | 안 질환을 치료 또는 예방하기 위한 간섭 ｒｎａ 분자의 자기-상보적 ａａｖ 매개 전달 |
| GB201106395D0 (en) * | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| DK4005603T3 (da) * | 2011-04-22 | 2024-11-25 | Univ California | Adeno-associerede virus-virioner med variant kapsid og fremgangsmåder til anvendelse heraf |
| EP2554662A1 (en) * | 2011-08-05 | 2013-02-06 | M Maria Pia Cosma | Methods of treatment of retinal degeneration diseases |
| MX366804B (es) * | 2012-02-11 | 2019-07-25 | Genentech Inc | Translocaciones de la r-espondina y sus metodos de uso. |
| WO2013170078A1 (en) * | 2012-05-09 | 2013-11-14 | Oregon Health & Science University | Adeno associated virus plasmids and vectors |
| IL251178B (en) | 2014-09-16 | 2022-07-01 | Genzyme Corp | Adeno-associated viral vector for the treatment of glaucoma myocilin (myoc) |
-
2015
- 2015-09-16 IL IL251178A patent/IL251178B/en unknown
- 2015-09-16 KR KR1020267001828A patent/KR20260019013A/ko active Pending
- 2015-09-16 JP JP2017534525A patent/JP6673923B2/ja active Active
- 2015-09-16 SG SG10201913430VA patent/SG10201913430VA/en unknown
- 2015-09-16 CA CA2961523A patent/CA2961523C/en active Active
- 2015-09-16 AU AU2015317756A patent/AU2015317756B2/en active Active
- 2015-09-16 BR BR112017005235-0A patent/BR112017005235B1/pt active IP Right Grant
- 2015-09-16 CN CN202211533202.3A patent/CN116585492A/zh active Pending
- 2015-09-16 RU RU2017112972A patent/RU2718047C2/ru active
- 2015-09-16 CN CN201580061882.5A patent/CN107001436B/zh active Active
- 2015-09-16 RU RU2020111038A patent/RU2746991C2/ru active
- 2015-09-16 SG SG11201702055PA patent/SG11201702055PA/en unknown
- 2015-09-16 SG SG10201902285SA patent/SG10201902285SA/en unknown
- 2015-09-16 KR KR1020177010012A patent/KR102612871B1/ko active Active
- 2015-09-16 KR KR1020237042363A patent/KR102916865B1/ko active Active
- 2015-09-16 MX MX2017003426A patent/MX2017003426A/es unknown
- 2015-09-16 US US15/511,595 patent/US10821193B2/en active Active
- 2015-09-16 EP EP15772133.3A patent/EP3194601B1/en active Active
-
2017
- 2017-03-15 MX MX2023005998A patent/MX2023005998A/es unknown
- 2017-03-16 ZA ZA2017/01881A patent/ZA201701881B/en unknown
-
2020
- 2020-03-04 JP JP2020036344A patent/JP7097398B2/ja active Active
-
2022
- 2022-04-12 AU AU2022202413A patent/AU2022202413A1/en not_active Abandoned
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