JP2017529395A5 - - Google Patents
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- Publication number
- JP2017529395A5 JP2017529395A5 JP2017534525A JP2017534525A JP2017529395A5 JP 2017529395 A5 JP2017529395 A5 JP 2017529395A5 JP 2017534525 A JP2017534525 A JP 2017534525A JP 2017534525 A JP2017534525 A JP 2017534525A JP 2017529395 A5 JP2017529395 A5 JP 2017529395A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seq
- myoc
- aav2
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051299P | 2014-09-16 | 2014-09-16 | |
| US62/051,299 | 2014-09-16 | ||
| PCT/US2015/050515 WO2016044478A1 (en) | 2014-09-16 | 2015-09-16 | Adeno-associated viral vectors for treating myocilin (myoc) glaucoma |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036344A Division JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529395A JP2017529395A (ja) | 2017-10-05 |
| JP2017529395A5 true JP2017529395A5 (enExample) | 2018-10-25 |
| JP6673923B2 JP6673923B2 (ja) | 2020-03-25 |
Family
ID=58640637
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534525A Active JP6673923B2 (ja) | 2014-09-16 | 2015-09-16 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
| JP2020036344A Active JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020036344A Active JP7097398B2 (ja) | 2014-09-16 | 2020-03-04 | ミオシリン（ｍｙｏｃ）緑内障を処置するためのアデノ随伴ウイルスベクター |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10821193B2 (enExample) |
| EP (1) | EP3194601B1 (enExample) |
| JP (2) | JP6673923B2 (enExample) |
| KR (3) | KR20260019013A (enExample) |
| CN (2) | CN116585492A (enExample) |
| AU (2) | AU2015317756B2 (enExample) |
| BR (1) | BR112017005235B1 (enExample) |
| CA (2) | CA3280614A1 (enExample) |
| IL (1) | IL251178B (enExample) |
| MX (2) | MX2017003426A (enExample) |
| RU (2) | RU2718047C2 (enExample) |
| SG (3) | SG10201913430VA (enExample) |
| ZA (1) | ZA201701881B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL251178B (en) | 2014-09-16 | 2022-07-01 | Genzyme Corp | Adeno-associated viral vector for the treatment of glaucoma myocilin (myoc) |
| JP7287611B2 (ja) * | 2018-02-07 | 2023-06-06 | 学校法人日本医科大学 | 改良型アデノ随伴ウイルスベクター |
| US20210030719A1 (en) * | 2018-02-22 | 2021-02-04 | University Of South Florida | Grp94 inhibitors to treat steroid-induced ocular hypertensions and glaucomas |
| EP3930694A1 (en) | 2019-02-28 | 2022-01-05 | Regeneron Pharmaceuticals, Inc. | Adeno-associated virus vectors for the delivery of therapeutics |
| EP4255457A4 (en) * | 2020-12-03 | 2025-05-21 | University of Massachusetts | DEVELOPMENT OF NEW GENE THERAPEUTIC AGENTS FOR FIBRODYSPLASIA OSSIFICANS PROGRESSIVA |
| CN113032010B (zh) * | 2021-03-12 | 2022-09-20 | 歌尔科技有限公司 | 命令的传输控制方法、终端及计算机可读存储介质 |
| CA3224868A1 (en) * | 2021-06-28 | 2023-01-05 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for silencing myoc expression |
| AU2022408167A1 (en) | 2021-12-08 | 2024-06-06 | Regeneron Pharmaceuticals, Inc. | Mutant myocilin disease model and uses thereof |
| WO2023114446A2 (en) * | 2021-12-16 | 2023-06-22 | Peter Koulen | A machine learning-based framework using electroretinography for detecting early-stage glaucoma |
| CN117343152B (zh) * | 2023-04-18 | 2024-06-04 | 上海本导基因技术有限公司 | 一种用于治疗青光眼疾病的慢病毒样颗粒 |
| CN118546217B (zh) * | 2024-07-25 | 2024-10-29 | 广州译码基因科技有限公司 | 靶向小梁网、角膜缘及rpe的aav衣壳蛋白及其应用 |
| CN121449764B (zh) * | 2026-01-07 | 2026-05-19 | 山东伯桢生物科技有限公司 | 抑制Wnt信号通路的融合蛋白及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050130145A1 (en) | 2001-10-03 | 2005-06-16 | Henry Yue | Secreted proteins |
| GB0403600D0 (en) * | 2004-02-18 | 2004-03-24 | Trinity College Dublin | Methods and reagents for treating disease |
| WO2005117938A2 (en) | 2004-04-13 | 2005-12-15 | Regents Of The University Of Minnesota | Methods of treating ocular conditions |
| WO2008075796A1 (ja) | 2006-12-21 | 2008-06-26 | Kyowa Hakko Kirin Co., Ltd. | 血球回復促進剤 |
| AU2008308784B2 (en) * | 2007-10-01 | 2013-07-18 | Arrowhead Research Corporation | Self complementary AAV-mediated delivery of interfering RNA molecules to treat or prevent ocular disorders |
| GB201106395D0 (en) * | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| DK3693025T3 (da) * | 2011-04-22 | 2022-01-10 | Univ California | Adenoassocierede virus-virioner med variant capsid og fremgangsmåder til anvendelse heraf |
| EP2554662A1 (en) * | 2011-08-05 | 2013-02-06 | M Maria Pia Cosma | Methods of treatment of retinal degeneration diseases |
| BR112014019741A2 (pt) * | 2012-02-11 | 2020-12-22 | Genentech, Inc | Usos de um antagonista da via wnt, uso de uma terapia anticâncer, método de identificação de um indivíduo com câncer, métodos para prever, método de inibição da proliferação de uma célula de câncer, uso de um antagonista da translocação de r-spondina e antagonista da translocação de r-spondina isolado |
| EP3470523A1 (en) * | 2012-05-09 | 2019-04-17 | Oregon Health & Science University | Adeno associated virus plasmids and vectors |
| IL251178B (en) | 2014-09-16 | 2022-07-01 | Genzyme Corp | Adeno-associated viral vector for the treatment of glaucoma myocilin (myoc) |
-
2015
- 2015-09-16 IL IL251178A patent/IL251178B/en unknown
- 2015-09-16 CA CA3280614A patent/CA3280614A1/en active Pending
- 2015-09-16 SG SG10201913430VA patent/SG10201913430VA/en unknown
- 2015-09-16 KR KR1020267001828A patent/KR20260019013A/ko active Pending
- 2015-09-16 AU AU2015317756A patent/AU2015317756B2/en active Active
- 2015-09-16 RU RU2017112972A patent/RU2718047C2/ru active
- 2015-09-16 RU RU2020111038A patent/RU2746991C2/ru active
- 2015-09-16 KR KR1020177010012A patent/KR102612871B1/ko active Active
- 2015-09-16 KR KR1020237042363A patent/KR102916865B1/ko active Active
- 2015-09-16 EP EP15772133.3A patent/EP3194601B1/en active Active
- 2015-09-16 MX MX2017003426A patent/MX2017003426A/es unknown
- 2015-09-16 US US15/511,595 patent/US10821193B2/en active Active
- 2015-09-16 SG SG11201702055PA patent/SG11201702055PA/en unknown
- 2015-09-16 BR BR112017005235-0A patent/BR112017005235B1/pt active IP Right Grant
- 2015-09-16 CA CA2961523A patent/CA2961523C/en active Active
- 2015-09-16 JP JP2017534525A patent/JP6673923B2/ja active Active
- 2015-09-16 SG SG10201902285SA patent/SG10201902285SA/en unknown
- 2015-09-16 CN CN202211533202.3A patent/CN116585492A/zh active Pending
- 2015-09-16 CN CN201580061882.5A patent/CN107001436B/zh active Active
-
2017
- 2017-03-15 MX MX2023005998A patent/MX2023005998A/es unknown
- 2017-03-16 ZA ZA2017/01881A patent/ZA201701881B/en unknown
-
2020
- 2020-03-04 JP JP2020036344A patent/JP7097398B2/ja active Active
-
2022
- 2022-04-12 AU AU2022202413A patent/AU2022202413A1/en not_active Abandoned
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